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Search Results for " peptic ulcers "

19

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T4981	Anisotropine Methylbromide	Prostaglandin Receptor; AChR	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Anisotropine Methylbromide 是一种抗胆碱能药物，已用于缓解胃肠道痉挛和抑制胃酸分泌。
T25737	Linetastine TMK 688,TMK-688,TMK688	Lipoxygenase; LTR; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Linetastine (TMK-688) 是一种 5-脂氧合酶抑制剂(5-LOX)，能抑制白三烯的产生，并能拮抗组胺的作用。Linetastine可用于研究哮喘、动脉粥样硬化和消化性溃疡。
T23667	AGN-201904 AGN201904,AGN 201904	ATPase	Membrane transporter/Ion channel
	AGN-201904 是质子泵抑制剂，是一种奥美拉唑前药，可延缓衰老，可用于预防和治疗消化性溃疡。
T5051	Isopropamide Iodide	AChR	Neuroscience
	Isopropamide iodide 是长效季铵盐抗胆碱能药物。它用于研究消化性溃疡和其他胃肠道疾病，尤其是胃酸过多和运动过度。
T10221	Abeprazan hydrochloride DWP14012 hydrochloride,Fexuprazan hydrochloride	Proton pump	Membrane transporter/Ion channel
	Abeprazan hydrochloride (Fexuprazan hydrochloride) 是一种有效的、可逆的、具有口服活性的potassium-competitive acid 阻滞剂，通过竞争性的与钾离子结合抑制 H+，K+- ATPase，而无需酸激活。Abeprazan hydrochloride 是一种质子泵抑制剂(PPI)，通过减少胃酸的产生而起作用，可用于治疗胃酸相关疾病，如胃食管反流病(GERD)和消化性溃疡。
T4195	Betahistine PT 9 base,倍他司汀,Vasomotal,Serc base	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Betahistine (Vasomotal) 是可口服的组胺 H1 受体激动剂和 H3 受体的拮抗剂，可用作血管扩张剂，用于类风湿性关节炎的研究。
T12914	Siltenzepine	Others	Others
	Siltenzepine is an agent of anti-acid agent,and used in the treatment of peptic ulcers.
T2138L	Oxyphencyclimine Oxiphencycliminum,Antulcus,Zamanil,Manir,Caridan,Naridan
	Oxyphencyclimine is a muscarinic receptor antagonist (MRA) anticholinergic drug used to treat peptic ulcers.
T27640	Itriglumide CR-2945,CR2945,CR 2945
	Itriglumide, a CCK2 receptor antagonist, is used potentially for the treatment of peptic ulcers, dyspepsia, and gastroesophageal reflux disease (GERD).
T78237	Urease-IN-6
	Urease-IN-6为一种高效Urease抑制剂，IC50值为14.2 μM，适用于消化性溃疡和胃溃疡研究。
T32224	Isopropamide Priazimide,Dipramide,Piaccamide,Chloroisopropamide,Dipramid
	Isopropamide (R5) is a long-acting anticholinergic drug. It is used to treat peptic ulcers and other gastrointestinal disorders involving excess gastric acid (gastrointestinal acidosis) and hyperactivity.
T25104	Aprofene aprophen,Aprofenum
	Aprofene (Aprophen) is an antagonist of muscarinic and nicotinic acetylcholine receptors. It may be used in the therapy of peptic ulcers, endarteritis (inflammation of the inner shell of the artery), cholecystitis (inflammation of the gallbladder), and sp
T68206	Arbortristoside A
	Arbortristoside A is an anti-inflammatory and antinociceptive. This activity may be due to the inhibiting effect of prostaglandin, histamine and serotonin. Arbortristoside A has also been shown to act on ulcerations and may facilitate healing of peptic ulcers.
T33314	Methantheline Bromide Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide
	Methantheline Bromide is a synthetic spasmolytic used to relieve cramps or spasms of the stomach, bowel, and bladder. It is also useful for intestinal or gastric ulcers (peptic ulcer disease), intestinal problems, pancreatitis, gastritis, biliary dysmotil
T61228	Pirenzepine
	Pirenzepine (LS 519 free base) is a selective antagonist of the M1 muscarinic acetylcholine receptor (mAChR). It effectively inhibits gastric acid secretion and reduces muscle spasm, making it a valuable compound for investigating peptic ulcers. Additionally, Pirenzepine exhibits anti-proliferative activity against cancer cells [1] [2].
T0246L	Betahistine mesylate Extovyl,甲磺酸倍他司汀,Melopat,Meginalisk	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Betahistine mesylate (Extovyl) 是可口服的组胺 H1 受体激动剂和 H3 受体的拮抗剂，可用作血管扩张剂，用于类风湿性关节炎的研究。
T71801	Arbaprostil
	Arbaprostil is a synthetic prostaglandin E analog that protects gastric mucosa, prevents ulceration, and promotes healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inhibitor of pancreatic function and can inhibit the growth of experimental tumors. Arbaprostil is a prodrug for the potent PGE2.
T79656	Urease-IN-8
	Urease-IN-8 (Compound 5e) 为一竞争性脲酶 (Urease) 抑制剂，具IC50值为3.51 μM，Ki值为3.11 μM，主要用于消化性溃疡与胃溃疡研究。
T79652	Urease-IN-7
	Urease-IN-7 (Compound 5k)，作为竞争性Urease抑制剂，具有IC50为3.33 μM和Ki值为3.62μM。该化合物可用于消化性溃疡和胃溃疡研究。

化合物

Anisotropine Methylbromide

Cat.No: T4981

Target: Prostaglandin Receptor, AChR

Cat.No: T25737

Synonym: TMK 688,TMK-688,TMK688

Target: Lipoxygenase, LTR, Histamine Receptor

Cat.No: T23667

Synonym: AGN201904,AGN 201904

Target: ATPase

Isopropamide Iodide

Cat.No: T5051

Target: AChR

Abeprazan hydrochloride

Cat.No: T10221

Synonym: DWP14012 hydrochloride,Fexuprazan hydrochloride

Target: Proton pump

Cat.No: T4195

Synonym: PT 9 base,倍他司汀,Vasomotal,Serc base

Target: Histamine Receptor

Cat.No: T12914

Target: Others

Oxyphencyclimine

Cat.No: T2138L

Synonym: Oxiphencycliminum,Antulcus,Zamanil,Manir,Caridan,Naridan

Cat.No: T27640

Synonym: CR-2945,CR2945,CR 2945

Cat.No: T78237

Cat.No: T32224

Synonym: Priazimide,Dipramide,Piaccamide,Chloroisopropamide,Dipramid

Cat.No: T25104

Synonym: aprophen,Aprofenum

Arbortristoside A

Cat.No: T68206

Methantheline Bromide

Cat.No: T33314

Synonym: Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide

Cat.No: T61228

Betahistine mesylate

Cat.No: T0246L

Synonym: Extovyl,甲磺酸倍他司汀,Melopat,Meginalisk

Target: Histamine Receptor

Cat.No: T71801

Cat.No: T79656

Cat.No: T79652

Cat. No.	Product Name	Target	Signaling Pathways
T7908	DL-Methionine Methylsulfonium Chloride DL-蛋氨酸甲基氯化锍,维生素U	Others	Others
	DL-methionine methylsulfonium chloride 是天然的蛋氨酸衍生物。它能够有效保护胃粘膜，避免其受到乙醇诱导的损伤。
TN4659	Nimbin	COX	Immunology/Inflammation; Neuroscience
	Nimbin is an anti-pyretic, can be used to treat arthritis, hypoglycaemia, peptic ulcers, anti-secretory activity, and it can also be used as an antibiotic. Nimbin requires to elicit a 50% inhibition of this steroid hydroxylase activity in the three insect

天然产物

DL-Methionine Methylsulfonium Chloride

Cat.No: T7908

Synonym: DL-蛋氨酸甲基氯化锍,维生素U

Target: Others

Cat.No: TN4659

Target: COX

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