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Search Results for " mutans "

8

抑制剂 & 化合物

11

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T77521	HA5	Antibacterial	Microbiology/Virology
	HA5 具有抗菌活性，抑制变形链球菌 (Streptococcus mutans) 生物膜形成，IC50 值为 6.42 μM。HA5 抑制变形链球菌葡聚糖的产生和 eDNA 水平，但对链球菌的生长无抑制作用。
T77633	G43 G 43,G-43	Antibacterial; Transferase	Metabolism; Microbiology/Virology
	G43 是一种有效的选择性 glucosyltransferase 抑制剂，对 GtfB 和 GtfC 具有抑制作用，Kd 值分别为3.7 μM和46.9 nM。G43 在体内外具有抗变形链球菌 (S. mutans)活性，可用于研究龋齿。
T63252	Antibacterial agent 113
	Antibacterial agent 113 是有效的抗菌剂 (antibacterial)，对P.aeruginosa、S.mutans、B.subtilis、E.coli、E.faecalis、S.typhimuriumand 和S.aureus microorganisms 表现出抗菌作用，MIC 值均为 15625 μM。
T35487	Anacardic Acid Diene
	Anacardic acid diene is a polyunsaturated form of anacardic acid that has been found in cashew nut shell liquid. It has antibacterial activity against methicillin resistant S. aureus (MRSA) and S. mutans (MICs = 12.5 and 6.25 μg/ml, respectively). Anacardic acid diene has schistosomicidal activity against adult S. mansoni worms when used at a concentration of 100 μM. It also inhibits soybean lipoxygenase-1 in a time-dependent manner.
T80301	Aurein 3.1	Antibiotic	Microbiology/Virology
	Aurein 3.1为一种具备针对革兰氏阳性菌的抗菌活性的抗生素抗菌肽，MIC值显示对M. luteus、S. aureus、S. epidermis、S. mutans及B. subtilis的有效浓度分别为80, 50, 50, 50, 50 μM。
T80300	Aurein 2.6	Antibiotic	Microbiology/Virology
	Aurein 2.6为具有针对革兰氏阳性菌抗菌效力的抗生素肽。该化合物在抗菌活性上表现出对M. luteus、S. aureus、S. epidermis、S. mutans、B. subtilis的最小抑菌浓度（MIC）分别为25、25、30、25、30μM。
T35698	Octanoic Acid-13C
	Octanoic acid-13C is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.1 Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).2 Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA d...
T35452	β-Defensin-3 (human) (trifluoroacetate salt)
	β-Defensin-3 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It inhibits the growth of the periodontopathogenic and cariogenic bacteria F. nucleatum, S. mutans, S. sobrinus, S. salivarius, and L. casei (MICs = 12.5-100 mg/l). It also inhibits the growth of S. aureus, S. pyogenes, P. aeruginosa, E. coli, and C. albicans. β-Defensin-3 stimulates gene expression and production of IL-6, IL-10, CXC...

化合物

Cat.No: T77521

Target: Antibacterial

Cat.No: T77633

Synonym: G 43,G-43

Target: Antibacterial, Transferase

Antibacterial agent 113

Cat.No: T63252

Anacardic Acid Diene

Cat.No: T35487

Cat.No: T80301

Target: Antibiotic

Cat.No: T80300

Target: Antibiotic

Octanoic Acid-13C

Cat.No: T35698

β-Defensin-3 (human) (trifluoroacetate salt)

Cat.No: T35452

Cat. No.	Product Name	Target	Signaling Pathways
TN1774	Isobavachromene	Others; Antibacterial	Microbiology/Virology; Others
	Isobavachromene 是一种抗菌剂。
T4S0578	Guaijaverin 番石榴苷,Guajaverin,Quercetin-3-Arabinoside	Others; Antioxidant; Antibacterial	Microbiology/Virology; Others; oxidation-reduction
	Guaijaverin (Quercetin-3-Arabinoside) 是一种尿素酶抑制剂，IC50值为 120 μM，有抗氧化和抗变形链球菌作用。
T3866	Macelignan 安五脂素,Anwuligan,(+)-Anwulignan	Others; COX	Immunology/Inflammation; Neuroscience; Others
	Macelignan (Anwuligan) 是一种从肉豆蔻中分离得到的木脂素，具有抗炎、抗癌、抗糖尿病和神经保护活性。
T10933	D-Cysteine	Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology
	D-Cysteine 是一种大肠杆菌生长的有力抑制剂，是半胱氨酸的 D 型异构体。它由 D-氨基酸氧化酶介导产生 H2S，是一种对抗小脑共济失调的神经保护剂。 D-半胱氨酸可以抑制由变形链球菌和链球菌血红蛋白形成的两种生物膜的生长和致龋性。
TN1409	Asimilobine	AChR; Antifection	Microbiology/Virology; Neuroscience
	(-)-Asimilobine shows antioxidative, anti-acetylcholinesterase (AChE), anti-α±-glucosidase, anti-leishmanial and anti-fungal activities; it displays weak inhibition against Streptococcus mutans (ATCC 25175), with a minimum inhibition concentration (MIC) o
TN4097	Gancaonin G	Antifection	Microbiology/Virology
	Gancaonin G shows antibacterial effects on the MRSA strains with MIC values of 16 microg/ml, it also shows more moderate antibacterial activity against Streptococcus mutans.
T79993	Oleanolic aldehyde
	Oleanolic aldehyde 是一种具有抗菌性质的化合物，能够抑制口腔内细菌生长。该化合物对变形链球菌和牙龈卟啉单胞菌——与龋齿和牙周病有关的细菌——显示出显著的抑制效果，其最低抑菌浓度(MICs)分别为488 μg/mL和250 μg/mL。
T38706	Erlose
	Erlose, a trisaccharide present in soybean aphid honeydew and composed of sucrose, acts as a sweetener substitute to inhibit dental caries formation by oral microorganisms, primarily Streptococcus mutans. Erlose can serve as a reference compound in high-performance liquid chromatography (HPLC) methods employed for the analysis of sugar content in various food samples.
TN4471	Lysicamine	IL Receptor; Antifection	Immunology/Inflammation; Microbiology/Virology
	Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 microg mL(-1). Lysicamine has antimicrobial and anti-inflammation activity, the mini
TN4399	Kushenol C	SGLT; NF-κB; ROS; BACE; Antifection	GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB
	Kushenol C is a good 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenger, and it exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2). Kushenol C shows antimicrobial activity against Staphylococcus aureus and Streptococcus mutan
TN4437	Licorisoflavan A	MMP; IL Receptor; NF-κB; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; NF-κB; Proteases/Proteasome
	Licorisoflavan A shows weak scavenging activity against superoxide anion radical, it and licoricidin have potential for the development of novel host-modulating strategies for the treatment of cytokine and/or MMP-mediated disorders such as periodontitis.L

天然产物

Isobavachromene

Cat.No: TN1774

Target: Others, Antibacterial

Cat.No: T4S0578

Synonym: 番石榴苷,Guajaverin,Quercetin-3-Arabinoside

Target: Others, Antioxidant, Antibacterial

Cat.No: T3866

Synonym: 安五脂素,Anwuligan,(+)-Anwulignan

Target: Others, COX

Cat.No: T10933

Target: Endogenous Metabolite, Antibacterial

Cat.No: TN1409

Target: AChR, Antifection

Cat.No: TN4097

Target: Antifection

Oleanolic aldehyde

Cat.No: T79993

Cat.No: T38706

Cat.No: TN4471

Target: IL Receptor, Antifection

Cat.No: TN4399

Target: SGLT, NF-κB, ROS, BACE, Antifection

Licorisoflavan A

Cat.No: TN4437

Target: MMP, IL Receptor, NF-κB, DNA/RNA Synthesis

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