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Search Results for " isoflavonoid "

1

抑制剂 & 化合物

13

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T35403	(±)-Equol 4'-sulfate (sodium salt)
	(±)-Equol 4’-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol .[1] It has been used as a standard for the quantification of unconjugated equol in rat plasma.[2]

化合物

(±)-Equol 4'-sulfate (sodium salt)

Cat.No: T35403

Cat. No.	Product Name	Target	Signaling Pathways
TN1521	Colutehydroquinone	Antifection; Antifungal	Microbiology/Virology
	Colutehydroquinone 是一种从Colutea arborescens 的根皮中提取的异黄酮，具有抗真菌活性。
T3848	7,2′-Dihydroxy-3′,4′-dimethoxyisoflavan 7-O-β-D-glucoside Isomucronulatol 7-O-glucoside,7,2'-dihydroxy-3',4'-dimethoxyisoflavane-7-O-glucoside,黄芪异黄烷苷	Others	Others
	7,2′-Dihydroxy-3′,4′-dimethoxyisoflavan 7-O-β-D-glucoside (Isomucronulatol 7-O-glucoside) 是一种具有生物活性的异黄酮，分离自黄芪中。
T8212	Dichotomitin	Others	Others
	Dichotomitin 是一种提取自Belamcanda chinensis 根茎中的异黄酮。
T2815	Puerarin 葛根素,Kakonein	5-HT Receptor	GPCR/G Protein; Neuroscience
	Puerarin (Kakonein) 是从葛根中提取的一种异黄酮，是一种5-HT2C 受体拮抗剂。
T13768	(+)-Medicarpin	Estrogen/progestogen Receptor	Endocrinology/Hormones
	(+)-Medicarpin, a pterocarpan, is an isoflavonoid compound derived from multiple medicinal plant species such as Sophora japonica, Zollernia paraensis, Platymiscium yucatamun, Machaerium aristulatum, and Platymiscium floribundum. It exhibits potent inhibition of osteoclastogenesis and facilitates bone healing and increased bone mass through osteoblast differentiation, which is mediated by the estrogen receptor (ER) β.
T2882	Genistin 染料木甙,Genistoside,Genistein glucoside,Genistein 7-glucoside,Genistine,Genistein 7-O-β-D-glucopyranoside,染料木苷	Apoptosis; Estrogen Receptor/ERR; Others	Apoptosis; Endocrinology/Hormones; Others
	Genistin (Genistoside) 是一种植物雌激素家族的异黄酮，是一种抗脂肪生成剂。它通过调节ERalpha 信号通路抑制乳腺癌细胞生长和促进凋亡细胞死亡。
T1737	Genistein NPI 031L,三叶草,染料木素,金雀异黄酮	Apoptosis; EGFR; Endogenous Metabolite; Autophagy	Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Metabolism; Tyrosine Kinase/Adaptors
	Genistein (NPI 031L) 是一种大豆异黄酮，是一种多重的酪氨酸激酶抑制剂，通过改变细胞凋亡，细胞周期和血管生成以及抑制转移对多种癌症有化疗作用。
T6491	(-)-(S)-Equol (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol,雌马酚	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	(-)-(S)-Equol (4',7-Dihydroxyisoflavan) 是雌激素受体β的高亲和力配体。
T4000	(±)-Equol Equol,(±)-雌马酚,(R,S)-Equol	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Drug Metabolite	Endocrinology/Hormones; Metabolism
	(±)-Equol ((R,S)-Equol) 是 equol 的外消旋体。它对 ERα 和 ERβ 的 EC50s of 分别为 200 和 74 nM。Equol 是大豆异黄酮黄豆苷和大豆黄素的代谢产物。
TN4800	Pisatin	NADPH-oxidase; P450	Immunology/Inflammation; Metabolism
	Pisatin is an isoflavonoid phytoalexin synthesized by pea (Pisum sativum L.).
T81842	Mbamiloside A
	Mbamiloside A (compound 4)为从Lophira alata茎心材中分离得到的一种天然异黄酮衍生物。
T81454	Piscerygenin
	Piscerygenin (compound 4)，一种可从Piscidia erythrina根皮中分离得到的异黄酮天然产物。
TN2766	2'-Hydroxydaidzein	Cannabinoid Receptor; Antioxidant	GPCR/G Protein; oxidation-reduction
	2'-Hydroxydaidzein 是一种在植物中发现的异黄酮类植物素，是一种天然化合物。2'-Hydroxydaidzein 具有抗氧化活性，主要由o -氢键解离焓(BDE)和氢原子转移(HAT)机制驱动。2'-Hydroxydaidzein 抑制炎症细胞中的化学介质，可能对治疗和预防与化学介质产生过多有关的中枢和外周炎症性疾病有作用。2'-Hydroxydaidzein 对大鼠中性粒细胞和formyl-Met-Leu-Phe/cytochalasin B（fMLP/CB）的释放具有抑制作用，IC（50）值分别为2.8+/-0.1和5.9+/-1.4 microM。

天然产物

Colutehydroquinone

Cat.No: TN1521

Target: Antifection, Antifungal

7,2′-Dihydroxy-3′,4′-dimethoxyisoflavan 7-O-β-D-glucoside

Cat.No: T3848

Synonym: Isomucronulatol 7-O-glucoside,7,2'-dihydroxy-3',4'-dimethoxyisoflavane-7-O-glucoside,黄芪异黄烷苷

Target: Others

Cat.No: T8212

Target: Others

Cat.No: T2815

Synonym: 葛根素,Kakonein

Target: 5-HT Receptor

Cat.No: T13768

Target: Estrogen/progestogen Receptor

Cat.No: T2882

Synonym: 染料木甙,Genistoside,Genistein glucoside,Genistein 7-glucoside,Genistine,Genistein 7-O-β-D-glucopyranoside,染料木苷

Target: Apoptosis, Estrogen Receptor/ERR, Others

Cat.No: T1737

Synonym: NPI 031L,三叶草,染料木素,金雀异黄酮

Target: Apoptosis, EGFR, Endogenous Metabolite, Autophagy

Cat.No: T6491

Synonym: (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol,雌马酚

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

Cat.No: T4000

Synonym: Equol,(±)-雌马酚,(R,S)-Equol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Drug Metabolite

Cat.No: TN4800

Target: NADPH-oxidase, P450

Cat.No: T81842

Cat.No: T81454

2'-Hydroxydaidzein

Cat.No: TN2766

Target: Cannabinoid Receptor, Antioxidant

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