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68

抑制剂 & 化合物

6

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T1196	Iodixanol 碘克沙醇,Visipaque,Acupaque	Others	Others
	Iodixanol (Visipaque) 是含碘的非离子放射性造影剂。
T19368	Hypromellose Celacol HPM 5000,HPMC,羟丙甲纤维素,(Hydroxypropyl)methyl cellulose	Others	Others
	Hypromellose (HPMC) 是一种水溶性的亲水性非离子纤维素醚。
T7116	Sodium gualenate Guaiazulenesulfonate sodium,磺酸钠	Others	Others
	Sodium gualenate (Guaiazulenesulfonate sodium) 是一种桂皮烯的亲水性衍生物，具有良好的抗炎和愈伤活性，常用于十二指肠溃疡，胃溃疡和胃炎的研究。
T19506	PEG400	Others	Others
	PEG400 是一种强亲水性聚乙二醇，可作为多种物质的优良溶剂，广泛用于多种药物制剂中。
T8836	CY5-SE triethylamine salt Fluorolink Cy5 triethanolamine salt,Cy5-SE (triethylamine salt)	Others	Others
	CY5-SE triethylamine salt (Fluorolink Cy5 triethanolamine salt) 是一种用于标记肽, 蛋白质, 寡核苷酸的氨基基团的反应染料 (Ex=649 nm; Em=670 nm)。
T34268	Raxofelast IRFI016,IRFI-016,IRFI 016
	Raxofelast (IRFI-016) 具有治疗糖尿病并发症和动脉粥样硬化的潜力
T10208	A-69412 N-1-(Fur-3-ylethyl)-N-hydroxyurea	Lipoxygenase	Metabolism
	A-69412 (N-1-(Fur-3-ylethyl)-N-hydroxyurea) 是一种特异性的 5-脂氧合酶 (5-LO) 的可逆抑制剂。 A-69412 能用于哮喘和溃疡性结肠炎，以及其他炎症和过敏症状的研究。
T14589	Biotin-PEG3-acid 18-[(3AS,4S,6AR)-六氢-2-氧代-1H-噻吩并[3,4-D]咪唑-4-基]-14-氧代-4,7,10-三氧杂-13-氮杂十八烷酸	Others; PROTAC Linker	Others; PROTAC
	Biotin-PEG3-acid 是一种属于 PEG 类的、生物素标记的 PROTAC linker，可用于 PROTAC 分子的合成。
T19287	TPGS-750-M DL-alpha-Tocopherol methoxypolyethylene glycol succinate	Others	Others
	DL-α-tocopherol methoxypolyethylene glycol succinate solution (TPGS-750-M) is a hydrophilic lipid molecule that acts as a surfactant.
T25245	CHM-1-P-Na
	CHM-1-P-Na is used as a hydrophilic prodrug of CHM-1.
T27417	Glutathione arsenoxide GSAO
	Glutathione arsenoxide is a hydrophilic derivative of phenylarsine oxide (PAO), a protein tyrosine phosphatase inhibitor. Glutathione arsenoxide inhibits angiogenesis and tumour growth.
T71441	Glutathione palmitamide
	Glutathione palmitamide is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T70602	Glutathione glycylethyl ester
	Glutathione glycylethyl ester is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T24668	Propargyl-PEG4-CH2CO2-NHS
	Propargyl-PEG4-CH2CO2-NHS is a PEG derivative containing a propargyl group and an NHS group. The hydrophilic PEG spacer increases solubility in aqueous media.
T26255	Tei 6472 Tei6472,Tei-6472
	Tei 6472 is a more hydrophilic form of TEI-1338 which is a novel, selective lipoxygenase inhibitor.
T21141	Decylene glycol Decane-1,2-diol,AI3-16595,1,2-Decanediol
	Decylene glycol is used as an antimicrobial agent in cosmetics. It also suppresses the fluidity of the hydrophobic and hydrophilic groups in the phospholipid membrane of liposomes.
T27790	Labradimil RMP-7,ALK-01-040,Receptor-mediated permeabiliser-7,DRG0182,DRG 0182,DRG-0182
	Labradimil is a bradykinin B2 receptor agonist. Labradimil increases the permeability of human brain microvascular endothelial cell monolayers. Labradimil enhances delivery of hydrophilic chemotherapeutics and increases survival in rats with metastatic tu
T69992	Glutathione sodium
	Glutathione sodium is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T40861	Nerindocianine
	Nerindocianine is a hydrophilic, fluorescent diagnostic contrast agent that is predominantly metabolized by the kidneys, enabling non-invasive, intraoperative ureteral imaging.
T70331	Glutathione sulfonate
	Glutathione sulfonate is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T68833	Glutathione sulfinanilide
	Glutathione sulfinanilide is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T70831	Glutathione maleimide
	Glutathione maleimide is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T30477	Bis-PEG5-thiol
	Bis-PEG5-thiol is a PEG derivative containing two thiol groups. The thiol groups react with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The hydrophilic PEG spacer increases solubility in aqueous media.
T68202	Glutathione diethyl ester
	Glutathione diethyl ester is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T20904	m-PEG11-Tos
	M-PEG11-Tos is a PEG derivative containing a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. For nucleophilic substitution reactions, the tosyl group is a good leaving group.
T18232	Mal-amido-(CH2COOH)2	Others	Others
	Mal-amido-(CH2COOH)2, also known as compound 7a, is an intermediate compound that contains maleimidoethyl for use in hydrophilic ADC linker synthesis[1].
TD0016	Sulfo-Cy5.5 cadaverine Cy5.5,尸胺
	Sulfo-Cyanine5.5 is a water soluble cyanine dye for far red / NIR applications such as in vivo imaging. The dye possesses four sulfonate groups that render it highly hydrophilic and water soluble. As well as other cyanines, sulfo-Cyanine5.6 has an outstan ' ( ' ( ' ( ' ( ' ( '
T32121	Hydroxy-PEG3-NHS
	Hydroxy-PEG3-NHS is a PEG derivative containing a hydroxyl group with an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. T
T30274	Azido-PEG4-Ala-Ala-Asn(Trt)-PAB
	Azido-PEG4-Ala-Ala-Asn(Trt)-PAB is a PEG derivative conjugated with a peptide via an amide bond. The azide group on the PEG end enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.
T20849	Hydroxy-PEG3-acid
	Hydroxy-PEG3-acid is a PEG derivative containing a hydroxyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functi
T20973	Thiol-C2-PEG2-OH Thiol-PEG3-alcohol,HS-PEG3-OH
	Thiol-PEG3-alcohol is a PEG derivative containing a hydroxyl group and a thiol group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
T31835	Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP
	Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP is a peptide reagent for ADC conjugation that possesses a cleavable peptide sequence. The hydrophilic PEG spacer increases solubility in aqueous media.
T20328	Biotin-PEG7-amine
	Biotin-PEG7-amine is a PEG derivative containing a biotin group and a terminal primary amine group. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound.
T20850	Hydroxy-PEG14-acid
	Hydroxy-PEG14-acid is a PEG derivative containing a hydroxyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive funct
T30273	Azido-PEG4-acrylate
	Azido-PEG4-acrylate is a crosslinker containing an azide group and an acrylate group. The azide group enables Click Chemistry and the acrylate group enables Michael addition. The hydrophilic PEG spacer increases solubility in aqueous media.
T82561	di-DTPA TL
	di-DTPA TL，作为一种亲水性的二价DTPA衍生物，主要用于肿瘤学研究中作为半抗原。
T17727	CCK2R Ligand-Linker Conjugates 1	Others	Others
	CCK2R Ligand-Linker Conjugate 1 is a hydrophilic peptide linker that conjugates to the cytotoxic antimicrotubule agents Desacetyl Vinblastine Hydrazide (DAVBH) and Tubulysin B Hydrazide (TubBH) as ligand-linker conjugates[1].
T30173	Aspartyllysine Asp-lys
	Aspartyllysine is a hydrophilic dipeptide widely distributed in nature. It is present in wheat, fish, and other nutrients. It is excreted by the kidney-specific high-affinity H+/peptide cotransport system.
T20915	Azido-PEG2-t-butyl ester
	Azido-PEG2-t-butyl ester is a PEG derivative containing a t-butyl ester and an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. Under acidic conditions, the t-butyl protected carboxyl group can be deprotected.
T32120	Hydroxy-PEG1-methylamine
	Hydroxy-PEG1-methylamine is a PEG derivative containing a hydroxyl group with a methylamine group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive funct
T20899	m-PEG1-acid
	M-PEG1-acid is a PEG derivative containing a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. In the presence of activators (e.g. EDC, DCC), the terminal carboxylic acid can be reacted with primary amine groups t
T20837	Fmoc-N-amido-PEG12-acid
	Fmoc-N-amido-PEG12-acid is a PEG derivative, it contains a Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. Under the basic conditions, the Fmoc group can be deprotected to obtain the f
T74566	Phospholipid-PEG-Biotin (MW 5000)
	Phospholipid-PEG-Biotin (MW 5000)为含有磷脂的PEG衍生物，适用于脂质体和细胞表面的修饰，及胰岛细胞移植。Phospholipid具亲水性“头部”与疏水性“尾部”结构，PEG为亲水性低毒聚合物，生物素则作为酶辅因子，用于蛋白质标记。
TP2174	3X (DYKDDDDK) Peptide	Others	Others
	The DYKDDDDK-tag system utilizes a short, hydrophilic 8- amino-acid peptide that is fused to the protein of interest1. The DYKDDDDK peptide binds to the antibody M1. To improve the detection of the DYKDDDDK tag the 3x (DYKDDDDK) system has been developed.
T33490	m-PEG12-aldehyde
	m-PEG12-aldehyde is a PEG derivative containing an aldehyde group. Aldehyde is reactive to hydrazide and aminooxy groups which are commonly used in biomolecular probes for labeling and crosslinking carbonyls (oxidized carbohydrates). The hydrophilic PEG s
T20903	m-PEG12-Mal
	M-PEG12-Mal is a PEG derivative containing a maleimide group. The hydrophilic PEG spacer increases solubility in aqueous media. The maleimide group could form a covalent bond with a thiol group , enabling the further connection of biomolecule with a thiol
T20901	m-PEG12-NHS ester
	M-PEG12-NHS ester is a PEG derivative containing an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label amine-modified oligonucleotides, the primary amines (-NH2) of proteins, and other amine-con
T77767L	GLF16 FA
	GLF16 FA 是一种亲水性荧光 SBB 类似物，可使用流式细胞术和活细胞分选来快速检测衰老细胞。
TD0015	Sulfo-Cy5.5 ethylenediamine Cy5.5,乙二胺
	Sulfo-Cyanine5.5 is a water soluble cyanine dye for far red / NIR applications such as in vivo imaging. The dye possesses four sulfonate groups that render it highly hydrophilic and water soluble. As well as other cyanines, sulfo-Cyanine5.5 has an outstanding extinction coefficient that makes it a bright fluorescent label for the far red region.
T71953	Thiol-PEG2-acid
	Thiol-PEG2-acid is a PEG derivative containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

化合物

Cat.No: T1196

Synonym: 碘克沙醇,Visipaque,Acupaque

Target: Others

Cat.No: T19368

Synonym: Celacol HPM 5000,HPMC,羟丙甲纤维素,(Hydroxypropyl)methyl cellulose

Target: Others

Sodium gualenate

Cat.No: T7116

Synonym: Guaiazulenesulfonate sodium,磺酸钠

Target: Others

Cat.No: T19506

Target: Others

CY5-SE triethylamine salt

Cat.No: T8836

Synonym: Fluorolink Cy5 triethanolamine salt,Cy5-SE (triethylamine salt)

Target: Others

Cat.No: T34268

Synonym: IRFI016,IRFI-016,IRFI 016

Cat.No: T10208

Synonym: N-1-(Fur-3-ylethyl)-N-hydroxyurea

Target: Lipoxygenase

Biotin-PEG3-acid

Cat.No: T14589

Synonym: 18-[(3AS,4S,6AR)-六氢-2-氧代-1H-噻吩并[3,4-D]咪唑-4-基]-14-氧代-4,7,10-三氧杂-13-氮杂十八烷酸

Target: Others, PROTAC Linker

Cat.No: T19287

Synonym: DL-alpha-Tocopherol methoxypolyethylene glycol succinate

Target: Others

Cat.No: T25245

Glutathione arsenoxide

Cat.No: T27417

Synonym: GSAO

Glutathione palmitamide

Cat.No: T71441

Glutathione glycylethyl ester

Cat.No: T70602

Propargyl-PEG4-CH2CO2-NHS

Cat.No: T24668

Cat.No: T26255

Synonym: Tei6472,Tei-6472

Decylene glycol

Cat.No: T21141

Synonym: Decane-1,2-diol,AI3-16595,1,2-Decanediol

Cat.No: T27790

Synonym: RMP-7,ALK-01-040,Receptor-mediated permeabiliser-7,DRG0182,DRG 0182,DRG-0182

Glutathione sodium

Cat.No: T69992

Cat.No: T40861

Glutathione sulfonate

Cat.No: T70331

Glutathione sulfinanilide

Cat.No: T68833

Glutathione maleimide

Cat.No: T70831

Cat.No: T30477

Glutathione diethyl ester

Cat.No: T68202

Cat.No: T20904

Mal-amido-(CH2COOH)2

Cat.No: T18232

Target: Others

Sulfo-Cy5.5 cadaverine

Cat.No: TD0016

Synonym: Cy5.5,尸胺

Hydroxy-PEG3-NHS

Cat.No: T32121

Azido-PEG4-Ala-Ala-Asn(Trt)-PAB

Cat.No: T30274

Hydroxy-PEG3-acid

Cat.No: T20849

Thiol-C2-PEG2-OH

Cat.No: T20973

Synonym: Thiol-PEG3-alcohol,HS-PEG3-OH

Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP

Cat.No: T31835

Biotin-PEG7-amine

Cat.No: T20328

Hydroxy-PEG14-acid

Cat.No: T20850

Azido-PEG4-acrylate

Cat.No: T30273

Cat.No: T82561

CCK2R Ligand-Linker Conjugates 1

Cat.No: T17727

Target: Others

Cat.No: T30173

Synonym: Asp-lys

Azido-PEG2-t-butyl ester

Cat.No: T20915

Hydroxy-PEG1-methylamine

Cat.No: T32120

Cat.No: T20899

Fmoc-N-amido-PEG12-acid

Cat.No: T20837

Phospholipid-PEG-Biotin (MW 5000)

Cat.No: T74566

3X (DYKDDDDK) Peptide

Cat.No: TP2174

Target: Others

m-PEG12-aldehyde

Cat.No: T33490

Cat.No: T20903

m-PEG12-NHS ester

Cat.No: T20901

Cat.No: T77767L

Sulfo-Cy5.5 ethylenediamine

Cat.No: TD0015

Synonym: Cy5.5,乙二胺

Thiol-PEG2-acid

Cat.No: T71953

Cat. No.	Product Name	Target	Signaling Pathways
T2A2509	Laurocapram 月桂氮酮,Tranzone,Azone,N-Lauryl caprolactam,N-0252,月桂氮卓酮,N-Dodecylcaprolactam	Others	Others
	Laurocapram (N-Lauryl caprolactam) 是吸收促进剂，对于亲脂性和亲水性物质都是一种最有效的吸收剂。
T2532	Tauroursodeoxycholate Taurolite,牛磺熊去氧胆酸,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA	Apoptosis; ERK; P450; Caspase; Endogenous Metabolite	Apoptosis; MAPK; Metabolism; Proteases/Proteasome
	Tauroursodeoxycholate (UR 906)，又称 ursodoxicoltaurine，是一种高度亲水性的三级胆汁酸，在人体内以低浓度产生。Tauroursodeoxycholate 是 ursodeoxycholic acid 更亲水的形式，而 ursodeoxycholic acid 是人类体内自然产生的更丰富的胆汁酸。Tauroursodeoxycholate 正在研究用于几种疾病，如原发性胆汁性肝硬化(PBC)、胰岛素抵抗、淀粉样变性、囊性纤维化、胆汁淤滞和肌萎缩性侧索硬化症。
TJA2398	Taurodeoxycholic acid sodium hydrate Sodium taurodeoxycholate monohydrate,Taurodeoxychloic Acid sodium hydrate,Taurohyodeoxycholic acid sodium salt,牛磺猪去氧胆酸	Apoptosis; Caspase	Apoptosis; Proteases/Proteasome
	Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate) 通过阻断钙介导的凋亡通路和 Caspase-12的活化来阻止细胞凋亡。它可用于原发性胆汁性肝硬化、胰岛素抵抗、淀粉样变性、囊性纤维化、胆汁淤积和肌萎缩侧索硬化症。
T13708	Glycol chitosan 羟乙基脱乙酰壳多糖,乙二醇壳聚糖	Antibacterial	Microbiology/Virology
	Glycol chitosan 是具有亲水性乙二醇支链的壳聚糖衍生物。它抑制大肠杆菌，金黄色葡萄球菌和肠炎链球菌的生长，MIC 值分别为 4 μg/mL，32 μg/m L 和 <0.5 μg/mL。它可增强 Glycine max Harosoy 63W 细胞的膜通透性和渗漏。
T4826	L-Histidine monohydrochloride monohydrat	Others; Endogenous Metabolite	Metabolism; Others
	L-Histidine monohydrochloride monohydrat 是一种 α-氨基酸。 L-异构体是 22 种蛋白质氨基酸之一，即蛋白质的组成部分。
T78465	H-γ-Glu-Gln-OH γ-Glutamylglutamine,γ-Glu-Gln
	H-γ-Glu-Gln-OH 是一种水溶性肽类化合物，用于药物结合。该载体特征为高溶解度、药物负载效能、优良生物相容性、低毒性，并能增强抗癌药物对肿瘤的靶向作用及疗效。

天然产物

Cat.No: T2A2509

Synonym: 月桂氮酮,Tranzone,Azone,N-Lauryl caprolactam,N-0252,月桂氮卓酮,N-Dodecylcaprolactam

Target: Others

Tauroursodeoxycholate

Cat.No: T2532

Synonym: Taurolite,牛磺熊去氧胆酸,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA

Target: Apoptosis, ERK, P450, Caspase, Endogenous Metabolite

Taurodeoxycholic acid sodium hydrate

Cat.No: TJA2398

Synonym: Sodium taurodeoxycholate monohydrate,Taurodeoxychloic Acid sodium hydrate,Taurohyodeoxycholic acid sodium salt,牛磺猪去氧胆酸

Target: Apoptosis, Caspase

Glycol chitosan

Cat.No: T13708

Synonym: 羟乙基脱乙酰壳多糖,乙二醇壳聚糖

Target: Antibacterial

L-Histidine monohydrochloride monohydrat

Cat.No: T4826

Target: Others, Endogenous Metabolite

H-γ-Glu-Gln-OH

Cat.No: T78465

Synonym: γ-Glutamylglutamine,γ-Glu-Gln

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