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Search Results for " copper "

89

抑制剂 & 化合物

10

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T31008	Copper probe CF4 Copper probe CF-4,Copper probe CF 4,Copper fluor CF4,CF4 prob
	Copper probe CF4 (Copper fluor CF4) 是一种荧光铜探针，可用于研究结肠癌。
T1254	Chlorophyllin sodium copper salt Chlorophyllin copper sodium complex,Chlorophyllin,叶绿素铜钠盐,Chlorophyllin coppered trisodium salt,Sodium-copper chlorin e6	Others	Others
	Chlorophyllin sodium copper salt (Chlorophyllin coppered trisodium salt) 是一种由 Chlorophyll 衍生的铜钠盐的半合成混合物，常用作食品添加剂。
T8422	DIETHYLDITHIOCARBAMIC ACID COPPER SALT	Others	Others
	DIETHYLDITHIOCARBAMIC ACID COPPER SALT 是一种应用广泛的工业化合物。它已被用作各种生化和生理实验中的螯合剂，包括涉及金属、蛋白质和酶的实验，也作为络合剂合成包括杂环化合物在内的各种有机化合物，以及用作纯化蛋白质的试剂。
TP1158	Copper tripeptide [N2-(N-甘氨酰-L-组氨酰)-L-赖氨酸]铜,GHK-Cu	Others; Endogenous Metabolite	Metabolism; Others
	Copper tripeptide (GHK-Cu) 是天然存在的三肽，首先从人血浆中分离，但也能够在唾液和尿液中发现。它能够提高成纤维细胞中胶原蛋白，弹性蛋白，蛋白多糖和糖胺聚糖中信使 RNA 的产生。在伤口愈合期间，它能够通过蛋白水解从现有的细胞外蛋白质中除去，并且用作炎性和内皮细胞的化学引诱物。它是皮肤再生中多种细胞途径的天然调节剂。
T12953	Sodium copper chlorophyllin B	Influenza Virus; HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Sodium copper chlorophyllin B 对流感病毒和HIV 有抗病毒活性，IC50s 值都是 50 到 100 μM。
T81404	Prezatide copper Bisprezatide copper,PC 1020,Iamin
	Prezatide Copper（亦称Iamin）具有促进伤口愈合的多重特性，且用于抑制脱发。
T60191	Cuprous iodide Iodocopper,Copper (I) iodide	Antibiotic	Microbiology/Virology
	Cuprous iodide (Iodocopper) 是一种抗菌化合物。
T65090	Copper(II) gluconate
	Copper(II) gluconate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65090，CAS号为 527-09-3。
T67981	Copper histidine
	Copper histidine 抑制了Ctr1介导的奥沙利铂在体外的细胞摄取，而不会改变奥沙利铂在体内DRG 组织中的铂或神经毒性的积累。Copper histidine 通过口服治疗 Menkes 疾病。
T20213	Copper oxychloride Blitox,Basic copper chloride,Blitox 50,Agrizan,Areecop
	Copper oxychloride is an agent of fungicide.
T65167	EDTA copper(II) disodium salt	Antibiotic	Microbiology/Virology
	EDTA copper(II) disodium salt 是一种金属螯合剂，具有抗菌、抗炎、抗氧化活性，可减缓金属离子造成的损伤，可维持蛋白纯化过程中的渗透压，可用于研究神经系统疾病。
T82681	Copper tripeptide-3 AHK-Cu
	AHK-Cu 是一种生物活性肽，具促进毛发生长功能，已作为化妆品成分使用。
T6170	Elesclomol 伊利司莫,STA-4783	Apoptosis; HSP; Reactive Oxygen Species	Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB
	Elesclomol (STA-4783) 是一种氧化应激诱导剂，也是一种高度亲脂性的铜离子载体。Elesclomol 可以诱导肿瘤细胞凋亡，用于铜死亡相关研究。Elesclomol 还可以抑制 FDX1 介导的 Fe-S 簇生物合成。
T21876	DC_AC50	Apoptosis; Others	Apoptosis; Others
	DC_AC50 是一种 Atox 和 CCS 的双抑制剂，是一种抑制细胞内铜伴侣作为减少/预防获得性化疗耐药性的手段。它与 Atox1 和 CCS 结合并减少癌细胞增殖和肿瘤生长。
T14667	BLT-1	Others; HCV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	BLT-1 是一种氨基硫脲铜螯合剂，是一种选择性清除受体 B1 型 (SR-BI) 抑制剂，抑制高密度脂蛋白 (HDL) 和 SR-BI 介导的细胞之间的脂质转移。
T40996	Coppersensor 1 Coppersensor 1,CS1	Others	Others
	Coppersensor 1 (CS1) 是一种基于硼二吡咯亚甲基的荧光传感器，用于选择性和灵敏地检测生物样品中的铜 (I) 离子 (Cu + )。 Coppersensor 1 可以使用任何类型的荧光显微镜进行成像，包括落射荧光、共焦和多光子。
T5965	Ditiocarb sodium Sodium diethyldithiocarbamate,二乙基二硫代氨基甲酸钠	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Ditiocarb sodium (Sodium diethyldithiocarbamate) 是一种铜胶结率的促进剂。它可降低HIV 感染。
T31907	Gamma-Methylleucine L-Neopentylglycine,gamma-Methyl-L-leucine,3-叔丁基-L-丙氨酸,2-Amino-3-tert-butylpropionic acid	Others	Others
	Gamma-Methylleucine (2-Amino-3-tert-butylpropionic acid) 是铜催化的不对称迈克尔反应的辅助剂。
T34956	Triplin	Others	Others
	Triplin 是铜离子的螯合剂。 Triplin 影响铜离子从 ATX1 到 RAN1 的传输。
T15069	DBCO-PEG4-Biotin ADIBO-NH-PEG2-Biotin	Others	Others
	DBCO-PEG4-Biotin (ADIBO-NH-PEG2-Biotin) 是一种 azadibenzocyclooctyne-biotin 衍生物，含有生物素基团和 4 个 PEG。DBCO-PEG4-Biotin 是一种用途广泛的生物素酰化试剂，能通过无铜催化烷基叠氮化反应 (SPAAC) 将生物素的一部分引入叠氮标记的生物分子中。
T65013	Cuprizone	Others	Others
	Cuprizone 是一种铜螯合剂。Cuprizone 可用于诱导小鼠精神分裂症。Cuprizone 可诱导少突胶质细胞死亡，诱导脱髓鞘反应。
T21300	Trientine-2HCl Triethylenetetramine,Trientine HCl,Trientine,盐酸三乙烯四胺,Triethylene tetramine,TETA,Trien	Others	Others
	Trientine-2HCl (Trien) 是一种螯合剂，通过结合和去除体内的铜来治疗威尔逊氏病。曲恩汀还可用作肝豆状核变性中铜的螯合剂，环氧树脂的稳定剂，等电聚焦的两性电解质。
T2229	Tetraethylenepentamine Pentahydrochloride	Others	Others
	Tetraethylenepentamine Pentahydrochloride 是一种高亲和力的铜和锌螯合剂。
T0876	Clioquinol Chinoform,Iodochlorhydroxyquin,氯碘羟喹	Mitophagy; Antibiotic; Autophagy; Antifungal	Autophagy; Microbiology/Virology
	Clioquinol (Iodochlorhydroxyquin) 是一种局部抗真菌药，具有抗肿瘤活性。它作为口服抗菌剂，可研究腹泻和皮肤感染。
T7086	Tris(benzyltriazolylmethyl)amine 三[(1-苄基-1H-1,2,3-三唑-4-基)甲基]胺,TBTA	Others	Others
	Tris(benzyltriazolylmethyl)amine (TBTA) 是一种能作为生化工具的配体，可用于标记蛋白质和酶。
T83971L	LCC-12 FA	Antiviral; Antibacterial	Immunology/Inflammation; Microbiology/Virology
	LCC-12 FA 是一种由二甲双胍组成的二聚体，通过靶向线粒体铜（ii）从而诱导 NAD（H）池减少。LCC-12 FA 可减少细菌和病毒感染小鼠模型中的炎症，可用于研究代谢疾病。
T15076	DBCO-S-S-PEG3-biotin 生物素-PEG3-二硫-DBCO	Others; PROTAC Linker	Others; PROTAC
	DBCO-S-S-PEG3-biotin 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。
T50049	4-Methylhistamine hydrochloride	Others	Others
	4-Methylhistamine hydrochloride 已被证明能抑制铜依赖性酶如酪氨酸酶和多巴胺β-羟化酶的活性，还被证明可以调节参与细胞周期调节和凋亡的基因的表达。
T60278	Tyrosinase-IN-2	Tyrosinase	Proteases/Proteasome
	Tyrosinase-IN-2 (compound 67) 是一种有效的酪氨酸酶抑制剂。酪氨酸酶是一种含铜金属酶，负责黑色素生物合成和酶促褐变中的限速催化步骤。Tyrosinase-IN-2 具有研究皮肤美白剂和食品防腐剂的潜力。
T0983L	DL-Penicillamine 3-Sulfanylvaline,DL-青霉胺	Antibiotic	Microbiology/Virology
	DL-Penicillamine (3-Sulfanylvaline) 是一种螯合剂，推荐用于去除威尔逊病患者体内多余的铜。它仅存在于使用或服用该药物的个体中。它是青霉素类抗生素最具特征的降解产物。它被用作抗风湿药和威尔逊病的螯合剂。
T71885	Sodium 2-mercaptobenzothiazole
	Sodium 2-mercaptobenzothiazole is the sodium salt of mercaptobenzothiazole, and is used as a copper corrosion inhibitor.
T31971	Glycyllysine Gly-lys,Glycyl-L-lysine
	Glycyllysine is a dipeptide. It can be used to study the interactions of the lysine side chain with copper in Glycyl-L-lysine-copper(II) complex.
T36499	CuATSM
	The metallo-protein Cu/Zn-superoxide dismutase (SOD1) is a ubiquitous enzyme responsible for scavenging superoxide radicals. Mutations in SOD1, which alter its metal binding capacity and can result in protein misfolding and aggregation, have been linked to familial amyotrophic lateral sclerosis (ALS). Cu-ATSM is an orally bioavailable, blood-brain barrier permeable complex that has traditionally been used in cellular imaging experiments to selectively label hypoxic tissue via its susceptibility ...
T15066	DBCO-NHS ester 2	Others	Others
	DBCO-NHS ester 2 is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs). It is a Dibenzylcyclooctyne (DBCO) derivative specifically designed for application in copper-free click chemistry [1].
T40794	HEPPSO
	HEPPSO is a zwitterionic buffer with a working pH range of 7.1-8.5. It exhibits strong copper(II) binding capability and a pK value of 7.84 at a concentration of 2.0 mM.
T20946	Bismuth oxide Bismuth sesquioxide,Bismuth trioxide,Bismutum-oxydatum,Bismuthous oxide
	Bismuth(III) oxide is a common starting point for bismuth chemistry. It is usually obtained as a by-product of the smelting of copper and lead ores. Bismuth trioxide is commonly used as a replacement of red lead to produce the “Dragon's eggs” effect in fi
T33631	Neocuproine Neocuproin
	Neocuproine 是一种铜（I）螯合剂，可增强电场刺激引起的输精管收缩的嘌呤能成分，常被用作配位试剂和铜离子检测剂。Neocuproine 与铜离子形成稳定的络合物，并可在某些化学反应和分析方法中起到催化作用。Neocuproine 作为铁和钴上的氧化还原活性配体平台，对NSC34细胞氧化损伤的保护作用。
T11317	FPA-124	Others	Others
	FPA-124 interacts with both the pleckstrin homology (PH) and the kinase domains of Akt. FPA-124 induces apoptosis. FPA-124, a cell-permeable copper complex, is a selective Akt inhibitor with an IC50 of 0.1 μM.
T21356	4-(Trifluoromethyl)phenylboronic acid
	4-(Trifluoromethyl)benzeneboronic acid is used to N-arylate imidazoles and amines with copper-exchanged fluorapatite, as well as used in microwave-promoted cross-coupling with acid chlorides leading to aryl ketones.
T30662	C.I. 74240 NSC 324570,NSC-324570,NSC324570
	C.I. 74240 is a copper-containing dye used as a gelling agent for lubricants, for staining of bacteria and for the dyeing of histiocytes and fibroblasts in vivo.
T29840	Alcian blue
	Alcian blue is a copper-containing dye used as a gelling agent for lubricants, for staining of bacteria and for the dyeing of histiocytes and fibroblasts in vivo.
T19974	Propargyl-PEG3-azide Propargyl-PEG3-amine
	Propargyl-PEG3-amine is a PEG derivative containing a propargyl group and an amino group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper-catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.
T40792	Cu(II)GTSM
	Cu(II)GTSM, a cell-permeable copper-complex, effectively inhibits GSK3β and shows inhibitory effects against Amyloid-β oligomers (AβOs) while reducing tau phosphorylation. Additionally, Cu(II)GTSM decreases the abundance of Amyloid-β trimers. With its potential as an anticancer and antimicrobial agent, Cu(II)GTSM exhibits promising therapeutic capabilities.
T80934	Trisulfo-Cy5.5-Alkyne
	Trisulfo-Cy5.5-Alkyne 是近红外（NIR）荧光染料，含有叠氮基团，能参与铜催化的 Click 化学反应。
T20118	L-Penicillamine
	L-Penicillamine is a medication primarily. It is used for the treatment of Wilson's disease. It is also used for people with kidney stones who have high urine cystine levels, rheumatoid arthritis, copper poisoning, and lead poisoning.
T61460	Tyrosinase-IN-3
	Tyrosinase-IN-3 (compound 54) is a powerful tyrosinase inhibitor, an enzyme involved in the key catalytic step of melanin biosynthesis and enzymatic browning. As a copper-containing metalloenzyme, tyrosinase plays a crucial role in these processes. The compound shows promise for studying skin whitening agents and food preservatives [1].
T77774	tetrathiomolybdate
	Tetrathiomolybdate (TM) 通过其特征性硫桥Mo2S6O2簇促进细胞铜外排蛋白ATP7B的金属结合域(WLN4)二聚化，应用于威尔逊病(Wilson’s disease)的临床治疗。
T80933	Trisulfo-Cy5-Alkyne
	Trisulfo-Cy5-Alkyne是一种含有叠氮基团的点击化学试剂，可用于铜催化的Click化学反应，并兼具近红外（NIR）荧光染料的特性。
T76598	H-Ser-Tyr-OH
	H-Ser-Tyr-OH是一种由谷氨酸、甘氨酸和组氨酸组成的二肽。它能与铜离子形成的铜（II）配合物生成，表现出较强的自由基清除活性。此外，H-Ser-Tyr-OH还能增加deltorphin这一δ阿片受体配体的细胞内摄取。
T79531	SA-VA	PROTACs	PROTAC
	SA-VA是一种细胞内自组装PROTAC，采用叠氮化物和炔烃基团。它能选择性地在U87细胞中降解VEGFR-2与EphB4蛋白，并可利用肿瘤组织的内源性铜促成点击反应生成PROTAC。此外，SA-VA能够促进(apoptosis)并干预S期细胞周期。

化合物

Copper probe CF4

Cat.No: T31008

Synonym: Copper probe CF-4,Copper probe CF 4,Copper fluor CF4,CF4 prob

Chlorophyllin sodium copper salt

Cat.No: T1254

Synonym: Chlorophyllin copper sodium complex,Chlorophyllin,叶绿素铜钠盐,Chlorophyllin coppered trisodium salt,Sodium-copper chlorin e6

Target: Others

DIETHYLDITHIOCARBAMIC ACID COPPER SALT

Cat.No: T8422

Target: Others

Copper tripeptide

Cat.No: TP1158

Synonym: [N2-(N-甘氨酰-L-组氨酰)-L-赖氨酸]铜,GHK-Cu

Target: Others, Endogenous Metabolite

Sodium copper chlorophyllin B

Cat.No: T12953

Target: Influenza Virus, HIV Protease

Prezatide copper

Cat.No: T81404

Synonym: Bisprezatide copper,PC 1020,Iamin

Cat.No: T60191

Synonym: Iodocopper,Copper (I) iodide

Target: Antibiotic

Copper(II) gluconate

Cat.No: T65090

Copper histidine

Cat.No: T67981

Copper oxychloride

Cat.No: T20213

Synonym: Blitox,Basic copper chloride,Blitox 50,Agrizan,Areecop

EDTA copper(II) disodium salt

Cat.No: T65167

Target: Antibiotic

Copper tripeptide-3

Cat.No: T82681

Synonym: AHK-Cu

Cat.No: T6170

Synonym: 伊利司莫,STA-4783

Target: Apoptosis, HSP, Reactive Oxygen Species

Cat.No: T21876

Target: Apoptosis, Others

Cat.No: T14667

Target: Others, HCV Protease

Coppersensor 1

Cat.No: T40996

Synonym: Coppersensor 1,CS1

Target: Others

Ditiocarb sodium

Cat.No: T5965

Synonym: Sodium diethyldithiocarbamate,二乙基二硫代氨基甲酸钠

Target: HIV Protease

Gamma-Methylleucine

Cat.No: T31907

Synonym: L-Neopentylglycine,gamma-Methyl-L-leucine,3-叔丁基-L-丙氨酸,2-Amino-3-tert-butylpropionic acid

Target: Others

Cat.No: T34956

Target: Others

DBCO-PEG4-Biotin

Cat.No: T15069

Synonym: ADIBO-NH-PEG2-Biotin

Target: Others

Cat.No: T65013

Target: Others

Cat.No: T21300

Synonym: Triethylenetetramine,Trientine HCl,Trientine,盐酸三乙烯四胺,Triethylene tetramine,TETA,Trien

Target: Others

Tetraethylenepentamine Pentahydrochloride

Cat.No: T2229

Target: Others

Cat.No: T0876

Synonym: Chinoform,Iodochlorhydroxyquin,氯碘羟喹

Target: Mitophagy, Antibiotic, Autophagy, Antifungal

Tris(benzyltriazolylmethyl)amine

Cat.No: T7086

Synonym: 三[(1-苄基-1H-1,2,3-三唑-4-基)甲基]胺,TBTA

Target: Others

Cat.No: T83971L

Target: Antiviral, Antibacterial

DBCO-S-S-PEG3-biotin

Cat.No: T15076

Synonym: 生物素-PEG3-二硫-DBCO

Target: Others, PROTAC Linker

4-Methylhistamine hydrochloride

Cat.No: T50049

Target: Others

Tyrosinase-IN-2

Cat.No: T60278

Target: Tyrosinase

DL-Penicillamine

Cat.No: T0983L

Synonym: 3-Sulfanylvaline,DL-青霉胺

Target: Antibiotic

Sodium 2-mercaptobenzothiazole

Cat.No: T71885

Cat.No: T31971

Synonym: Gly-lys,Glycyl-L-lysine

Cat.No: T36499

DBCO-NHS ester 2

Cat.No: T15066

Target: Others

Cat.No: T40794

Cat.No: T20946

Synonym: Bismuth sesquioxide,Bismuth trioxide,Bismutum-oxydatum,Bismuthous oxide

Cat.No: T33631

Synonym: Neocuproin

Cat.No: T11317

Target: Others

4-(Trifluoromethyl)phenylboronic acid

Cat.No: T21356

Cat.No: T30662

Synonym: NSC 324570,NSC-324570,NSC324570

Cat.No: T29840

Propargyl-PEG3-azide

Cat.No: T19974

Synonym: Propargyl-PEG3-amine

Cat.No: T40792

Trisulfo-Cy5.5-Alkyne

Cat.No: T80934

L-Penicillamine

Cat.No: T20118

Tyrosinase-IN-3

Cat.No: T61460

tetrathiomolybdate

Cat.No: T77774

Trisulfo-Cy5-Alkyne

Cat.No: T80933

Cat.No: T76598

Cat.No: T79531

Target: PROTACs

Cat. No.	Product Name	Target	Signaling Pathways
Fr12596	3-Acetylcoumarin	Others	Others
	3-Acetylcoumarin 作为室温下铜催化 CN 偶联反应的实用配体。它具有神经保护和杀螨特性。
T0983	Penicillamine 青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine	Antibiotic	Microbiology/Virology
	Penicillamine (Artamine) 是一种 penicillin 的代谢降解产物，是一种螯合剂，可作用于威尔逊氏病。
TN5672	Puerol A
	Puerol A exhibits potent inhibitory effects on aldose reductase with IC50 values of 6.4 uM. dl-Puerol A has antioxdiant activity, it shows inhibitory effects on copper ion-induced protein oxidative modification of mouse brain homogenate in vitro.
T82956	Asparenyldiol Asparenydiol
	Asparenyldiol（Asparenydiol）为一类抗氧化剂且兼具点击化学试剂功能。该化合物含Alkyne基团，能够通过CuAAc与含Azide基团的分子发生反应。
T76129	Hemocyanin
	Hemocyanin是一种含铜的大分子呼吸蛋白，扮演着重要的非特异性先天免疫防御分子角色，具备酚氧化酶、抗病毒、抗菌、溶血及抗肿瘤活性。
TN2219	Sophoraisoflavone A 鲁冰花,砂生槐异黄酮 A	MRP; Antifection	Immunology/Inflammation; Microbiology/Virology
	Sophoraisoflavone A is a potential MRP inhibitor; it is also an inhibitor of germ tube growth in the AM fungus Gigaspora margarita, it strongly inhibited germ tube growth at 1.25 ug/disc. Sophoraisoflavone A shows inhibitory effects on copper-induced prot
T81170	Shishijimicin A
	Shishijimicin A是一款从子囊菌Didemnum proliferum中分离出的新型抗肿瘤剂，具备突出的细胞毒性及抗肿瘤活性。作为点击化学试剂，Shishijimicin A内含Alkyne基团，能够与含Azide基团的分子通过铜催化的叠氮-炔环加成反应(CuAAc)进行作用。
T81168	Shishijimicin C
	Shishijimicin C 是由子囊菌 Didemnum proliferum 分离得到的一种新型抗肿瘤剂，具有显著的细胞毒性和抗肿瘤活性。作为点击化学试剂，Shishijimicin C 含有Alkyne基团，能够通过铜催化的叠氮-炔环加成反应（CuAAc）与含Azide基团的分子反应。
T81958	Lacto-N-neodifucohexaose II LNnDFH II
	Lacto-N-neodifucohexaose II（Compd 9），一种关键的人乳四糖衍生物，为点击化学反应试剂。该化合物含 Azide 基团，适用于铜催化叠氮-炔环加成反应（CuAAc），与含 Alkyne 基团的分子反应。同时，它也能与含 DBCO 或 BCN 基团的分子，进行菌株促进的炔-叠氮环加成反应（SPAAC）。
T81169	Shishijimicin B
	Shishijimicin B为活性的烯二炔类化合物，具有强烈的细胞毒性，IC50值介于2.0 - 3.3 nM。此化合物表现出抗肿瘤活性，常用于癌症研究中。作为点击化学试剂，Shishijimicin B内含Alkyne基团，能通过含Azide基团的分子在铜催化下发生(CuAAc)反应。

天然产物

3-Acetylcoumarin

Cat.No: Fr12596

Target: Others

Cat.No: T0983

Synonym: 青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine

Target: Antibiotic

Cat.No: TN5672

Cat.No: T82956

Synonym: Asparenydiol

Cat.No: T76129

Sophoraisoflavone A

Cat.No: TN2219

Synonym: 鲁冰花,砂生槐异黄酮 A

Target: MRP, Antifection

Shishijimicin A

Cat.No: T81170

Shishijimicin C

Cat.No: T81168

Lacto-N-neodifucohexaose II

Cat.No: T81958

Synonym: LNnDFH II

Shishijimicin B

Cat.No: T81169

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