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Search Results for " conjunctivitis "

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抑制剂 & 化合物

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天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T1444	Lomefloxacin 洛美沙星,SC47111A	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Lomefloxacin (SC47111A) 是一种广谱喹诺酮类抗生素，具有抗菌活性。它可研究支气管炎、尿路感染、结膜炎、外耳炎和中耳炎。
T4563	Thonzylamine neohetramine,松齐拉敏	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Thonzylamine (neohetramine) 是可口服的H1组胺受体拮抗剂，具有抗组胺和抗过敏特性，可用于鼻充血、过敏性结膜炎和其他过敏性疾病的研究。
T3979	Emedastine LY188695,依美斯汀,Emadine	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Emedastine (LY188695) 是一种可口服的，选择性和高亲和力的组胺 H1受体拮抗剂，Ki 值为 1.3 nM。它是苯并咪唑衍生物，可用于过敏性鼻炎、过敏性皮肤疾病和过敏性结膜炎的研究。
T7893	Bepotastine Bepotastine free base,贝托斯汀	Others; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience; Others
	Bepotastine (Bepotastine free base) 是一种选择性可口服的组胺 H1 受体拮抗剂，可用于过敏性鼻炎、过敏性结膜炎、荨麻疹和瘙痒症的研究。
T1625	Lomefloxacin hydrochloride Lomefloxacin HCl,盐酸洛美沙星,Okacyn,Maxaquin	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Lomefloxacin hydrochloride (Okacyn) 是一种广谱喹诺酮类抗生素，具有抗菌活性。它可研究支气管炎、尿路感染、结膜炎、外耳炎和中耳炎。
T6405	Bepotastine Besilate Talion,TAU 284,苯磺酸贝托司汀,Bepreve,Bepotastine Beslilate	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Bepotastine Besilate (TAU 284) 是一种选择性可口服的组胺 H1 受体拮抗剂，可用于过敏性鼻炎、过敏性结膜炎、荨麻疹和瘙痒症的研究。
T21412	Ketorolac Toradol,Sprix,Acuvail,Macril,酮咯酸,Acular	COX	Immunology/Inflammation; Neuroscience
	Ketorolac (Acuvail) 是非甾体抗炎剂，是非选择性的COX 抑制剂，对 COX-1 和 COX-2 的IC50值分别为 20 和 120 nM。
T1269	Tripelennamine hydrochloride Pyribenzamine hydrochloride,去敏灵,Tripelennamine HCl,Pyribenzamine HCl,盐酸曲吡那敏	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Tripelennamine hydrochloride (Pyribenzamine hydrochloride) 是一种组胺 H1 拮抗剂，具有低镇静作用，但经常刺激胃肠道。
T21445	Naphazoline AK-Con,Naphcon-a,Clear Eyes,All Clear,萘甲唑林	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Naphazoline (Naphcon-a) 是一种具有显着 α 肾上腺素能活性的拟交感神经化合物。萘甲唑啉可用作血管收缩剂，当应用于粘膜时可快速减少肿胀。
T0446	Naphazoline hydrochloride 盐酸萘甲唑啉,Albalon,Rhinantin,Naphazoline HCl	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Naphazoline hydrochloride (Naphazoline HCl) 是一种咪唑啉衍生物，是一种眼血管收缩剂。
T1293	Gatifloxacin BMS 206584-01,PD 135432,CG5501,BMS-206584,AM-1155,加替沙星	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Gatifloxacin (CG5501) 是一种具有广谱抗菌活性的氟喹诺酮类抗生素。它可抑制大肠杆菌 DNA 解旋酶 (IC50=0.109 μg/ml) 和细菌 II 型拓扑异构酶(IC50=13.8 μg/ml)。在动物模型中，它有抗细菌性结膜炎作用。
T6488	Epinastine hydrochloride Alesion,Epinastine HCl,WAL-801CL HCl,依匹斯汀盐酸盐,Elestat	5-HT Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Epinastine hydrochloride (WAL-801CL HCl) 是抗组胺剂和肥大细胞稳定剂，是一种可口服的选择性组胺 H1 受体拮抗剂，可抑制 IL-8 释放，具有抗过敏作用。
T1170	Olopatadine hydrochloride 盐酸奥洛他定,Olopatadine HCl,KW4679,ALO4943A	5-HT Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Olopatadine hydrochloride (ALO4943A) 是一种抗组胺药，具有稳定肥大细胞的特性，用作治疗过敏性结膜炎的滴眼液。
T15772	Lodoxamide tromethamine U-42585E	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Lodoxamide tromethamine 是一种的肥大细胞稳定剂，具有抗过敏特性，可用于治疗哮喘和过敏性结膜炎的研究。
T4566	Lodoxamide Lodoxamidum,洛草氨酸	GPR; Histamine Receptor	Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Lodoxamide (Lodoxamidum) 是一种抗过敏药物，作为肥大细胞稳定剂，对治疗哮喘和过敏性结膜炎有效。
T2533	Alcaftadine R89674,Lastacaft,阿卡他定	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Alcaftadine (Lastacaft) 是一种 H1 组胺受体拮抗剂，用于预防与过敏性结膜炎相关的瘙痒。它是一种广谱抗组胺剂，对组胺H1和H2受体具有高亲和力，对H4受体的亲和力较低，还具有调节免疫细胞募集和肥大细胞稳定的作用。
TP2499	Human IgE Pentapeptide HEPP acetate Human IgE Pentapeptide HEPP acetate (62087-72-3 Free base）
	Human IgE Pentapeptide HEPP acetate 是一种五肽，在几种不同体系中均不能产生 IgE 抑制作用，可用于治疗结膜炎。
T77601	(2-{[2-(2-fluorophenoxy)ethyl]sulfanyl}-1H-benzimidazol-1-yl)acetic acid	GPR	Endocrinology/Hormones; GPCR/G Protein
	(2-{[2-(2-fluorophenoxy)ethyl]sulfanyl}-1H-benzimidazol-1-yl)acetic acid是一种前列腺素类 CRTH2拮抗剂，其IC50< 10 μM，可用于研究鼻炎、慢性阻塞性肺疾病、类风湿性关节炎、湿疹和结膜炎。
T21434	Sulfacetamide NSC 63871,磺胺醋酰,NSC-63871,Sebizon,Region,NSC63871,Sulphacetamide,Acetosulfamine	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Sulfacetamide (NSC-63871) 是一种抗生素，通过限制细菌生存所需的叶酸的存在来治疗睑缘炎或结膜炎，有潜力用于眼部感染的研究。
T1278	Astemizole Laridal,Histaminos,Paralergin,阿司咪唑	Potassium Channel; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience
	Astemizole (Laridal) 是一种长效、非镇静抗组胺药，用于治疗季节性过敏性鼻炎、哮喘、过敏性结膜炎和慢性特发性荨麻疹。它是组胺 H1 受体的拮抗剂，IC50值为 4 nM，还阻断 hERG K+通道，IC50值为 0.9 nM，具有抗胆碱能和止痒作用。
T25033	Alcaftadine carboxylic acid
	Alcaftadine is a novel antihistamine for preventing allergic conjunctivitis.
T22270	Besifloxacin	Others	Others
	Besifloxacin is the fourth generation of fluoroquinolones, which can be used to treat bacterial conjunctivitis
T25239	Chloramphenicol stearate Eusynthomycin,Chloramphenicol monostearate,Madomicetina
	Chloramphenicol stearate is an antibiotic useful for the therapy of numbers of bacterial infections. This includes an eye ointment to treat conjunctivitis.
T21388	Emedastine Difumarate Rapimine,DSSTox_CID_26911,AL-3432A,富马酸依美斯汀,KB-2413,Emedastine fumarate,KB 2413
	Emedastine Difumarate is a selective histamine H1 receptor antagonist with anti-allergic activity, prescribed for allergic conjunctivitis. Upon ocular administration, emedastine causes a dose-dependent inhibition of histamine-stimulated vascular permeabil
T0785L	Dexchlorpheniramine free base Polaramine,Dexchlorpheniramine Maleate,Mylaramine
	Dexchlorpheniramine Maleate, a histamine receptor antagonist, is used to treat urticaria, allergic rhinitis, allergic conjunctivitis and pruritus.
T21247	Carbinoxamine Allergefon,(+-)-Carbinoxamine,Paracarbinoxamine
	Carbinoxamine, an anticholinergic and antihistamine agent, is used for hay fever, angioedema, vasomotor rhinitis, mild urticaria, dermatographism and allergic conjunctivitis. It is a histamine antagonist, specifically an H1-antagonist.
T21462	Olopatadine Opatanol,Patanol,KW-4943A,KW-4679
	Olopatadine, an antihistamine, as well as anticholinergic and mast cell stabilizer, is used for the treatment of itching associated with allergic conjunctivitis (eye allergies). There is also a potential for Olopatadine to treat steroid rebound (red skin
T32700	Levocabastine Livostin,Bilina
	Levocarbastine is a second-generation H1 receptor antagonist for allergic conjunctivitis. It also acts as a potent selective antagonist for the neurotensin receptor NTS2 and is the first drug to be used to characterize different neurotensin subtypes.
T60590	Chloropyramine
	Chloropyramine 是竞争性可逆 H1 受体拮抗剂，可用于过敏性疾病的研究，例如结膜炎和支气管哮喘。Chloropyramine 表现出抗乳腺癌活性。
T60289	Pemirolast
	Pemirolast 是一种具有口服活性的抗过敏剂。Pemirolast 通过抑制感觉神经肽的释放来减轻紫杉醇超敏反应，可用于对支气管哮喘和结膜炎的研究。
T62669	Tripelennamine citrate
	Tripelennamine citrate 是一种乙二胺衍生物，是一种有效的组胺 H1 受体拮抗剂。Tripelennamine citrate 能够减少组织胺引起的机体过敏反应。Tripelennamine citrate 能够用于研究鼻炎、结膜炎、过敏性和过敏性反应。
T60392	Tripelennamine
	Tripelennamine 是一种乙二胺衍生物，是一种有效的组胺 H1受体拮抗剂，可减轻由组织胺引起的机体过敏反应。Tripelennamine 可用于鼻炎、结膜炎、过敏性和过敏性反应的研究。
T63965	Bepotastine tosylate
	Bepotastine tosylate 是一种选择性、口服具有活力的第二代组胺 H1 受体 (histamine H1 receptor) 拮抗剂，对组胺介导的神经生长因子 (NGF) 表达上调表现出抑制作用。Bepotastine tosylate 能够用于研究过敏性鼻炎，过敏性结膜炎和荨麻疹/瘙痒症。
T60496	Ketorolac hemicalcium
	Ketorolac (RS37619) hemicalcium 是一种非选择性的 COX 抑制剂，对 COX-1 的 IC50 为 20 nM，对 COX-2 的 IC50 为 120 nM。 Ketorolac hemicalcium 是一种非甾体类抗炎药 (NSAID)，可用作 0.5% 滴眼液，用于研究过敏性结膜炎、黄斑囊样水肿、术中瞳孔缩小和术后眼部炎症和疼痛等。 Ketorolac hemicalcium 也是一种可用于癌症研究的 DDX3 抑制剂 [1] [4]。

化合物

Cat.No: T1444

Synonym: 洛美沙星,SC47111A

Target: Topoisomerase, Antibacterial, Antibiotic

Cat.No: T4563

Synonym: neohetramine,松齐拉敏

Target: Histamine Receptor

Cat.No: T3979

Synonym: LY188695,依美斯汀,Emadine

Target: Histamine Receptor

Cat.No: T7893

Synonym: Bepotastine free base,贝托斯汀

Target: Others, Histamine Receptor

Lomefloxacin hydrochloride

Cat.No: T1625

Synonym: Lomefloxacin HCl,盐酸洛美沙星,Okacyn,Maxaquin

Target: Topoisomerase, Antibacterial, Antibiotic

Bepotastine Besilate

Cat.No: T6405

Synonym: Talion,TAU 284,苯磺酸贝托司汀,Bepreve,Bepotastine Beslilate

Target: Histamine Receptor

Cat.No: T21412

Synonym: Toradol,Sprix,Acuvail,Macril,酮咯酸,Acular

Target: COX

Tripelennamine hydrochloride

Cat.No: T1269

Synonym: Pyribenzamine hydrochloride,去敏灵,Tripelennamine HCl,Pyribenzamine HCl,盐酸曲吡那敏

Target: Histamine Receptor

Cat.No: T21445

Synonym: AK-Con,Naphcon-a,Clear Eyes,All Clear,萘甲唑林

Target: Adrenergic Receptor

Naphazoline hydrochloride

Cat.No: T0446

Synonym: 盐酸萘甲唑啉,Albalon,Rhinantin,Naphazoline HCl

Target: Adrenergic Receptor

Cat.No: T1293

Synonym: BMS 206584-01,PD 135432,CG5501,BMS-206584,AM-1155,加替沙星

Target: Topoisomerase, Antibacterial, Antibiotic

Epinastine hydrochloride

Cat.No: T6488

Synonym: Alesion,Epinastine HCl,WAL-801CL HCl,依匹斯汀盐酸盐,Elestat

Target: 5-HT Receptor, Histamine Receptor

Olopatadine hydrochloride

Cat.No: T1170

Synonym: 盐酸奥洛他定,Olopatadine HCl,KW4679,ALO4943A

Target: 5-HT Receptor, Histamine Receptor

Lodoxamide tromethamine

Cat.No: T15772

Synonym: U-42585E

Target: Histamine Receptor

Cat.No: T4566

Synonym: Lodoxamidum,洛草氨酸

Target: GPR, Histamine Receptor

Cat.No: T2533

Synonym: R89674,Lastacaft,阿卡他定

Target: Histamine Receptor

Human IgE Pentapeptide HEPP acetate

Cat.No: TP2499

Synonym: Human IgE Pentapeptide HEPP acetate (62087-72-3 Free base）

(2-{[2-(2-fluorophenoxy)ethyl]sulfanyl}-1H-benzimidazol-1-yl)acetic acid

Cat.No: T77601

Target: GPR

Cat.No: T21434

Synonym: NSC 63871,磺胺醋酰,NSC-63871,Sebizon,Region,NSC63871,Sulphacetamide,Acetosulfamine

Target: Others, Antibacterial, Antibiotic

Cat.No: T1278

Synonym: Laridal,Histaminos,Paralergin,阿司咪唑

Target: Potassium Channel, Histamine Receptor

Alcaftadine carboxylic acid

Cat.No: T25033

Cat.No: T22270

Target: Others

Chloramphenicol stearate

Cat.No: T25239

Synonym: Eusynthomycin,Chloramphenicol monostearate,Madomicetina

Emedastine Difumarate

Cat.No: T21388

Synonym: Rapimine,DSSTox_CID_26911,AL-3432A,富马酸依美斯汀,KB-2413,Emedastine fumarate,KB 2413

Dexchlorpheniramine free base

Cat.No: T0785L

Synonym: Polaramine,Dexchlorpheniramine Maleate,Mylaramine

Cat.No: T21247

Synonym: Allergefon,(+-)-Carbinoxamine,Paracarbinoxamine

Cat.No: T21462

Synonym: Opatanol,Patanol,KW-4943A,KW-4679

Cat.No: T32700

Synonym: Livostin,Bilina

Cat.No: T60590

Cat.No: T60289

Tripelennamine citrate

Cat.No: T62669

Cat.No: T60392

Bepotastine tosylate

Cat.No: T63965

Ketorolac hemicalcium

Cat.No: T60496

Cat. No.	Product Name	Target	Signaling Pathways
T8384	Gatifloxacin hydrochloride AM-1155 (hydrochloride),BMS-206584 (hydrochloride),PD135432 (hydrochloride),加替沙星盐酸盐	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Gatifloxacin hydrochloride (AM-1155 hydrochloride) 是一种氟喹诺酮类抗生素，有广谱抗菌活性。它可抑制大肠杆菌 DNA 解旋酶 (IC50=0.109 μg/ml)和细菌 II 型拓扑异构酶(IC50=13.8 μg/ml) 。它在动物模型中，可研究细菌性结膜炎。

天然产物

Gatifloxacin hydrochloride

Cat.No: T8384

Synonym: AM-1155 (hydrochloride),BMS-206584 (hydrochloride),PD135432 (hydrochloride),加替沙星盐酸盐

Target: Topoisomerase, Antibacterial, Antibiotic

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