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Search Results for " zanthoxylum "

1

抑制剂 & 化合物

17

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T19557	Sanshool	Others	Others
	Sanshool is a natural product isolated from Zanthoxylum bungeanum. Sanshool improves UVB-induced skin photodamage by targeting JAK2/STAT3-dependent autophagy.

化合物

Cat.No: T19557

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN2010	Ombuin 商陆黄素,商陆素	Antibacterial	Microbiology/Virology
	Ombuin 是一种从花椒中分离出的广谱抗菌剂，MIC 为 125 至 500 μg/mL。
TN1089	Hydroxy-β-sanshool Hydroxy-beta-sanshool	Others	Others
	Hydroxy-β-sanshool 是一种从胡椒中提取的辛辣化合物。
TN1174	Schinifoline	Apoptosis; cell cycle arrest	Apoptosis; Cell Cycle/Checkpoint
	Schinifoline 是从 Zanthoxylum schinifolium Sieb 中提取出来的一种喹啉酮衍生物，具有细胞毒性活性，可促进癌细胞放射敏感性，影响细胞循环周期和细胞凋亡。
T5S1959	(-)-Asarinin Fagarol,Sesamin,细辛脂素,Pseudocubebin,Eleutheroside B4,Episesamin,Asarinin	Antibacterial	Microbiology/Virology
	(-)-Asarinin (Eleutheroside B4) 是一种主要从 Zanthoxylum armatum 根部提取到的木脂素。
T8859	NITIDINE	Others	Others
	NITIDINE 是一种从花椒根中分离出来的具有生物活性的植物苯并菲啶生物碱。它具有抗癌、神经保护、抗疟疾、抗 HIV、镇痛、抗炎和抗真菌活性。
T2981	Xanthoxylin Brevifolin,Xanthoxyline,花椒素,2'-Hydroxy-4',6'-dimethoxyacetophenone	Others; Antifungal	Microbiology/Virology; Others
	Xanthoxylin (Brevifolin)e 是从Zanthoxylum simulans 中分离出来的是一种冰片和樟脑味化合物，有抗真菌和抗癫痫作用。
T5S0761	Nitidine chloride	Apoptosis; ERK; FAK; p38 MAPK; NF-κB; Topoisomerase; STAT; Parasite	Angiogenesis; Apoptosis; Cytoskeletal Signaling; DNA Damage/DNA Repair; JAK/STAT signaling; MAPK; Microbiology/Virology; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors
	Nitidine chloride 是从Zanthoxylum nitidum (Roxb) DC 中分离得到的，具有抗疟疾活性。它通过多个靶点通路，起抗癌作用，抑制STAT3、DNA 拓扑异构酶1和2A、ERK 和c-Src/FAK 相关信号通路。它通过MAPK 和NF-kB 途径抑制Lps 诱导的炎性细胞因子的产生。
TN3047	4-Methoxy-1-methylquinolin-2-one	Others	Others
	4-Methoxy-1-methylquinolin-2-one is a natural product from Zanthoxylum nitidum.
T82553	Dihydronitidine
	Dihydronitidine是从Zanthoxylum rhoifolium中提取的一种生物碱。
T13732	Hydroxy-Epsilon-Sanshool	Others	Others
	Hydroxy-Epsilon-Sanshool is an alkyl amide isolated from Zanthoxylum bungeanum. Hydroxy-Epsilon-Sanshool produces key tingling and numbing chemosensation.
T3833	Sanshodiol	Others	Others
	Sanshodiol是一种天然产物，属于芸香科花椒属，其产品编号为 T3833，CAS号为 54854-91-0。Sanshodiol可用作对照参考。
TN4687	O-Geranylconiferyl alcohol	Others	Others
	O-Geranylconiferyl alcohol是一种天然产物，属于芸香科花椒属，其产品编号为 TN4687，CAS号为 129350-09-0。O-Geranylconiferyl alcohol可用作对照参考。
TN2408	Evofolin B	Cannabinoid Receptor	GPCR/G Protein
	Evofolin B 是从Zanthoxylum ailanthoides 的茎皮中分离出来的天然化合物。Evofolin B 对人类中性粒细胞对甲酰-L-蛋氨酸-L-亮氨酸-L-苯丙氨酸/cytochalasin B（fMLP/CB）产生的超氧阴离子有抑制作用。
TN2159	Robustine 大叶桉亭,8-羟基白鲜碱,4-甲氧基呋喃并[2,3-B]喹啉-8-醇	PDE	Metabolism
	Robustine 是一种从 Dictamnus albus 获得的呋喃喹啉生物碱，在体外对人磷酸二酯酶 5 (hPDE5A) 具有抑制作用。
T8307	Hydroxy-α-sanshool 羟基-α-山椒素,Hydroxy-α-sanshool	Endogenous Metabolite; TRP/TRPV Channel	Membrane transporter/Ion channel; Metabolism
	Hydroxy-α-sanshool 是分离自胡椒的烷基酰胺，作为 TRPA1的共价激动剂和 TRPV1的非共价激动剂，EC50分别为69和 1.1 µM。
T38330	Collinin
	Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Collinin inhibits LPS-induced nitric oxide (NO) production (IC50 = 5.9 μM) and reduces COX-2 protein levels in RAW 264.7 cells.2 It completely inhibits aggregation of isolated rabbit platelets induced by arachidonic acid , collagen, or platelet activating factor (PAF) when used at a...
TN4931	(S)-(-)-beta-Citronellol	Others	Others
	(S)-(-)-beta-Citronellol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4931，CAS号为 7540-51-4。

天然产物

Cat.No: TN2010

Synonym: 商陆黄素,商陆素

Target: Antibacterial

Hydroxy-β-sanshool

Cat.No: TN1089

Synonym: Hydroxy-beta-sanshool

Target: Others

Cat.No: TN1174

Target: Apoptosis, cell cycle arrest

Cat.No: T5S1959

Synonym: Fagarol,Sesamin,细辛脂素,Pseudocubebin,Eleutheroside B4,Episesamin,Asarinin

Target: Antibacterial

Cat.No: T8859

Target: Others

Cat.No: T2981

Synonym: Brevifolin,Xanthoxyline,花椒素,2'-Hydroxy-4',6'-dimethoxyacetophenone

Target: Others, Antifungal

Nitidine chloride

Cat.No: T5S0761

Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite

4-Methoxy-1-methylquinolin-2-one

Cat.No: TN3047

Target: Others

Dihydronitidine

Cat.No: T82553

Hydroxy-Epsilon-Sanshool

Cat.No: T13732

Target: Others

Cat.No: T3833

Target: Others

O-Geranylconiferyl alcohol

Cat.No: TN4687

Target: Others

Cat.No: TN2408

Target: Cannabinoid Receptor

Cat.No: TN2159

Synonym: 大叶桉亭,8-羟基白鲜碱,4-甲氧基呋喃并[2,3-B]喹啉-8-醇

Target: PDE

Hydroxy-α-sanshool

Cat.No: T8307

Synonym: 羟基-α-山椒素,Hydroxy-α-sanshool

Target: Endogenous Metabolite, TRP/TRPV Channel

Cat.No: T38330

(S)-(-)-beta-Citronellol

Cat.No: TN4931

Target: Others

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