首页工具

登录

搜索结果

Search Results for " serd "

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T12832	Amcenestrant SAR439859	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Amcenestrant (SAR439859) 是一种有效的 ER 拮抗剂，具有 ER 降解活性，EC50为 0.2 nM。它是一种具有口服活性，非甾体和选择性雌激素受体降解剂 (SERD)。它可在 ER+乳腺癌中表现出强大的抗肿瘤功效和有限的交叉耐药性。
T9997	GLL 398	Estrogen Receptor/ERR	Endocrinology/Hormones
	GLL 398 是一种具有口服活性的选择性雌激素受体降解剂，IC50 为 1.14 nM。 GLL 398 在异种移植乳腺癌模型中阻断肿瘤生长。
T2243	Serdemetan JNJ-26854165,N-[2-(1H-吲哚-3-基)乙基]-N'-(4-吡啶基)-1,4-苯二胺	Apoptosis; Mdm2; E1/E2/E3 Enzyme; p53	Apoptosis; Ubiquitination
	Serdemetan (JNJ-26854165) 是一种 HDM2泛素连接酶拮抗剂，能诱导 p53野生型细胞的早期凋亡。
T39727	ERα degrader-2	ERK	MAPK
	ERα degrader-2 是一种具有选择性和有效性的雌激素受体 (SERD)降解剂，具有抗癌活性，抑制 ERα，对雌激素受体降解的 EC50 值为 0.3 nM。ERα degrader-2 可用于预防和治疗 HER 阳性乳腺癌。
T13674	Elacestrant 依拉司群,RAD1901	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Elacestrant (RAD1901) 是一种具有口服活性的、选择性的雌激素受体 (ER) 降解剂 (SERD)，能够作用于 ERα (IC50:48 nM)和 ERβ (IC50:870 nM)。
T13675	Elacestrant dihydrochloride RAD1901 dihydrochloride	Estrogen/progestogen Receptor	Endocrinology/Hormones
	Elacestrant dihydrochloride (DA-DKRAD1901 dihydrochloride) 是一种具有口服活性的的选择性雌激素受体 (ER) 降解剂 (SERD)，能够作用于 ERα (IC50:48 nM) 和 ERβ (IC50:870 nM)。
T70179	THIQ-40
	THIQ-40 is a novel potent erα antagonist and selective estrogen receptor degrader (serd), exhibiting good oral bioavailability, antitumor efficacy, and serd activity in vivo
T39499	Rintodestrant G1T48
	Rintodestrant (G1T48) is an orally active, non-steroidal, selective estrogen receptor degrader (SERD) that also functions as a CDK4/6 inhibitor.
T77724	OBHSA Oxabicycloheptane sulfonamide	Estrogen/progestogen Receptor	Endocrinology/Hormones
	OBHSA（Oxabicycloheptane sulfonamide）是一种新型选择性雌激素受体降解剂（SERD），可用于研究乳腺癌。
T74593	Taragarestrant meglumine
	Taragarestrant meglumine (D-0502) 是一种口服有效、选择性的雌激素受体 (estrogen receptor) 降解剂，展现了对各种ER+乳腺癌细胞系及移植模型的强大活性。
T63674	Imlunestrant
	Imlunestrant 是选择性的、口服具有活力的雌激素受体的降解剂(SERD)，能够用于 ER+ 和HER2 乳腺癌的研究。
T39118	AZD9496 maleate
	AZD9496 maleate is a highly potent and selective antagonist of the estrogen receptor alpha (ERα), exhibiting an IC50 value of 0.28 nM. This compound, AZD9496 maleate, is an orally bioavailable selective estrogen receptor degrader (SERD).
T39368	GNE-149
	GNE-149 is an orally bioavailable compound that acts as a full antagonist of estrogen receptor α (ERα) with an IC50 of 0.053 nM. It is also classified as a selective estrogen receptor degrader (SERD). GNE-149 holds potential for research in the field of breast cancer.
T74415	Imlunestrant tosylate
	Imlunestrant (LY-3484356) tosylate 是口服有效且选择性的雌激素受体(estrogen receptor, ER)降解剂(SERD)，具纯拮抗性。该化合物能持续抑制ER依赖的基因转录与细胞生长，适用于研究ER阳性(ER+)晚期乳腺癌(aBC)与子宫内膜样癌(EEC)。
T27289	Etacstil GW 5638,GW-5638,GW5638,DPC974,DPC 974,DPC-974
	GW5638 is a estrogen receptor ligand. GW5638 is a prodrug of its active metabolite GW7604. GW5638 appears to act as an antagonist in these in vitro systems, although in a manner distinct from other known ER modulators. GW5638 is also classified as a pseud

化合物

Cat.No: T12832

Synonym: SAR439859

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Cat.No: T9997

Target: Estrogen Receptor/ERR

Cat.No: T2243

Synonym: JNJ-26854165,N-[2-(1H-吲哚-3-基)乙基]-N'-(4-吡啶基)-1,4-苯二胺

Target: Apoptosis, Mdm2, E1/E2/E3 Enzyme, p53

ERα degrader-2

Cat.No: T39727

Target: ERK

Cat.No: T13674

Synonym: 依拉司群,RAD1901

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Elacestrant dihydrochloride

Cat.No: T13675

Synonym: RAD1901 dihydrochloride

Target: Estrogen/progestogen Receptor

Cat.No: T70179

Cat.No: T39499

Synonym: G1T48

Cat.No: T77724

Synonym: Oxabicycloheptane sulfonamide

Target: Estrogen/progestogen Receptor

Taragarestrant meglumine

Cat.No: T74593

Cat.No: T63674

AZD9496 maleate

Cat.No: T39118

Cat.No: T39368

Imlunestrant tosylate

Cat.No: T74415

Cat.No: T27289

Synonym: GW 5638,GW-5638,GW5638,DPC974,DPC 974,DPC-974

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼