Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0776 |
Phenothiazine
ENT 38,吩噻嗪 |
Dopamine Receptor; Antibacterial; Antibiotic; Antifungal | GPCR/G Protein; Microbiology/Virology; Neuroscience |
Phenothiazine (ENT 38) 是一种抗生素,具有杀虫,抗菌,驱虫和杀真菌活性。它也可研究神经系统疾病。 | |||
T34189 |
PTZ-256
phenothiazine derivative,PTZ256 |
||
PTZ-256 is a phenothiazine derivative with chemical name: 3-(10H-phenothiazin-10-yl)propane-1-amine. PTZ-256 has molecule weight 256, therefore, we call it as PTZ-256. | |||
T9827 |
carfenazine
|
Dopamine Receptor | GPCR/G Protein; Neuroscience |
carfenazine 靶向多巴胺受体,用于精神分裂症研究。 | |||
T10232 |
Acetophenazine dimaleate
|
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Acetophenazine dimaleate 是抗精神病试剂,能够有效治疗焦虑抑郁。 | |||
TNU0675 |
3-(4’-Carboxyphenyl)imino-3H-phenothiazine
|
||
3-(4'-Carboxyphenyl)imino-3H-phenothiazine is a Bio-reagent, fine chemical. | |||
T9353 |
OXOMEMAZINE
|
AChR; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Oxomemazine 是毒菌碱 M1 受体的选择性拮抗剂,具有明显的抗毒蕈碱活性。它是基于吩噻嗪的组胺 H1 受体阻滞剂,是抗组胺和抗胆碱能试剂,可用于咳嗽相关研究。 | |||
TNU0712 |
3-(2',5'-Disulfophenylimino)-3H-phenothiazine
|
||
3-(2',5'-Disulfophenylimino)-3H-phenothiazine is a Bio-reagent, fine chemical. | |||
T7943 |
Fluphenazine decanoate
|
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Fluphenazine decanoate 是一种高度连续的多巴胺 D2受体阻滞剂,是一种长效吩噻嗪抗精神病药,用于精神分裂症的研究。 | |||
T0642 |
2-Methoxyphenothiazine
|
Factor Xa | Metabolism |
2-Methoxyphenothiazine 为淡黄色或淡灰色固体。 | |||
T0622 |
2-Chlorophenothiazine
|
Others | Others |
2-Chlorophenothiazine 用作盐酸氯丙嗪的中间体。 | |||
T4117 |
Zuclopenthixol
珠氯噻醇,cis-Clopenthixol,Cisordinol,(Z)-Clopenthixol |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Zuclopenthixol (cis-Clopenthixol) 是一种多巴胺 D1/D2受体的拮抗剂,是一种噻吨衍生物。 | |||
T0068 |
Fluphenazine dihydrochloride
氟奋乃静盐酸盐,Prolixin,盐酸氟奋乃静,Fluphenazine hydrochloride |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Fluphenazine dihydrochloride (Prolixin) 是一种多巴胺受体D1/D2抑制剂。 | |||
T0766 |
Promazine hydrochloride
Romtiazin hydrochloride,Sinophenin hydrochloride,盐酸丙嗪 |
Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; AChR | GPCR/G Protein; Neuroscience |
Promazine hydrochloride (Romtiazin hydrochloride) 是一种抗精神病药,也是一种多巴胺受体 (D2) 拮抗剂,能够抑制多巴胺能神经传递。 | |||
T12777 |
RTC-5
TRC-382 |
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
RTC-5 (TRC-382) 是一种特别增强了抗癌活性的Phenothiazine 化合物,对EGFR驱动的癌症异种移植模型表现出显著的效果。其作用机制归因于同时抑制PI3K-AKT和RAS-ERK信号通路。 | |||
T1090 |
Perphenazine
Perphenazin,Etaperazine,Trilafon,奋乃静 |
CaMK; Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Perphenazine (Trilafon) 是吩噻嗪衍生物和多巴胺拮抗剂,具有止吐和抗精神病特性。它能够抑制5-HT2A 受体,α1A 肾上腺素能受体,多巴胺D2、D3、D2L 受体,以及组胺H1受体,对应的Ki 值分别为5.6、10、0.765、0.13、3.4 和 8 nM。 | |||
T0385 |
Prochlorperazine Maleate
Prochlorperazin,Capazine,Prochlorperazine dimaleate salt,Stemetil,Compazine,丙氯拉嗪 |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Prochlorperazine Maleate (Capazine) 是一种吩噻嗪类抗精神病药,主要用于治疗恶心、呕吐和眩晕。它比氯丙嗪更容易引起锥体外系疾病。 | |||
T50054 |
Opromazine hydrochloride
|
Others | Others |
Opromazine hydrochloride 属于吩噻嗪类抗精神病药物,通过阻断大脑中的多巴胺受体而降低多巴胺能通路的活性,主要用于治疗精神分裂症和精神病等精神疾病。 | |||
T0312 |
Toluidine Blue
氯托洛宁,Blutene chloride |
Others | Others |
Toluidine Blue (Blutene chloride) 是碱性噻嗪异染染料,能够高度亲和酸性组织成分,广泛应用于活体组织的重要染色及特殊染色。 | |||
T0302L |
Triflupromazine
Vesprin,Fluopromazine,Trifluopromazine,Adazine,Siquil |
||
Triflupromazine is a phenothiazine drug used as an antipsychotic and antiemetic. | |||
T19525 |
PPA-904
|
Others | Others |
PPA-904 is a specific phenothiazine photosensitizer,and used in photodynamic therapy. | |||
T23843L |
Butaperazine maleate
Tyrylen,Repoise maleate |
||
Butaperazine maleate, a phenothiazine derivative, is an antipsychotic. | |||
T40854 |
Imiclopazine
|
||
Imiclopazine is a phenothiazine derivative with good sedative, analgesic, antiaggressive and antiemetic effects. | |||
T3086L |
Mesoridazine free base
NSC-186066,NSC 186066,NSC186066,TPS23,Mesoridazine,NC-123 |
||
Mesoridazine (thioridazine EP impurity B) is a phenothiazine antipsychotic with effects similar to chlorpromazine. | |||
T23949 |
Dacemazine hydrochloride
Ahistan HCl,Dacemazine HCl,Histantine HCl,UNII-DK78VKA001 |
||
Dacemazine is a phenothiazine derivative that acts as a histamine antagonist at the H1 subtype. It was also assessed as a possible anticancer drug. | |||
T68193 |
Clopenthixol
|
||
Clopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. | |||
T68963 |
alpha-Clopenthixol dihydrochloride
|
||
alpha-Clopenthixol dihydrochloride is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. | |||
T31169 | D54 naponate | ||
D54 Naponate is a stored salt form of biologically active phenothiazine, which has good antitumor activity and can be maintained longer in the body. | |||
T18652 | RTC-30 | Others | Others |
RTC-30 is an optimized phenothiazine compound possessing potent anti-cancer properties. It is formulated with a hydroxylated linker (N) which enhances its oral bioavailability[1]. | |||
T69103 |
Clopenthixol decanoate
|
||
Clopenthixol decanoate is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. | |||
T23843 |
Butaperazine
Butyrylyperazine,Bayer 1362,Butaperazina,Butyrylperazine |
||
Butaperazine is a typical antipsychotic of the phenothiazine class. | |||
T33319 |
Methdilazine Hydrochloride
Bristaline,Dilosyn,Methdilazine Hcl,Tacaryl hydrochloride,Disyncran |
||
Methdilazine Hydrochloride is a first-generation phenothiazine class antihistamine with anticholinergic properties. | |||
T0445L1 |
Promethazine hibenzate
D-08768,D08768,D 08768 |
||
Promethazine is a neuroleptic medication and first-generation antihistamine of the phenothiazine family. | |||
T71160 |
Levomepromazine HCl
|
||
Levomepromazine HCl is a phenothiazine with pharmacological activity similar to that of both CHLORPROMAZINE and PROMETHAZINE. It has the histamine-antagonist properties of the antihistamines together with CENTRAL NERVOUS SYSTEM effects resembling those of chlorpromazine. | |||
T31844 |
Fonazine
Dimethodin,Banistyl,Dimetiotazine,Dimetotiazine,Dimethothiazine |
||
Forazine (dimethiazide) is a phenothiazine drug used in the treatment of migraine and is a serotonin antagonist and a histamine antagonist. | |||
T15026 |
Cyamemazine
|
5-HT Receptor | GPCR/G Protein; Neuroscience |
Cyamemazine, contains the phenothiazine chromophore, is a neuroleptic agent used as an anxiolytic. Cyamemazine is a potent 5-HT3 (Ki: 12 nM), 5-HT2A (Ki: 1.5 nM) and 5-HT2C (Ki: 75 nM) receptors antagonist with antipsychotic activity. | |||
T69407 | Fonazine hydrochloride | ||
Fonazine hydrochloride is a phenothiazine drug used for the treatment of migraine. It is a serotonin antagonist and histamine antagonist. | |||
T70997 |
Fonazine mesylate
|
||
Fonazine mesylate is a phenothiazine drug used for the treatment of migraine. It is a serotonin antagonist and histamine antagonist. | |||
T28282 |
Oxypertine
Win-18501,Forit,Win18501,Win 18501 |
||
Oxypertine is an indole-derivative antipsychotic with general properties similar to those of the chlorpromazine and phenothiazine. Oxypertine is used as a treatment for various psychoses including mania, schizophrenia, disturbed behaviour, and severe anx | |||
T34072 |
Pipotiazine
19366 RP,Pipotiazina,Pipotiazinum,Piportil L4,Pipothiazine |
||
Pipotiazine has less sedating and a weak propensity for causing hypotension or potentiating the effects of CNS depressants and anesthetics among the different phenothiazine derivatives. However, it produces a high incidence of extra pyramidal reactions. I | |||
T68133 |
quisultazine
|
||
Quisultazine 是一种非中枢作用的吩噻嗪衍生物,可归类为非抗H2抗分泌剂。 | |||
T0218 |
Biperiden
Bipariden,Akineton,KL 373,比哌立登,Biperidine |
AChR | Neuroscience |
Biperiden (Bipariden) 是中枢 M1胆碱受体阻断剂,有抗帕金森症活性。 | |||
T81348 |
PTZ-LD
|
||
PTZ-LD是一种phenothiazine衍生的荧光探针,专门用于检测脂滴(LDs)。在LDs中,PTZ-LD展示出显著的高特异性发射(Ex/Em=488/570-620 nm)。此探针还可以应用于糖尿病性白内障(DC)的研究工作。 | |||
T61915 |
Thiethylperazine
|
||
Thiethylperazine 是一种吩噻嗪衍生物。Thiethylperazine 是具有口服活性的组胺H1受体和多巴胺D2受体拮抗剂。Thiethylperazine 也是选择性的ABCC1激活剂,可减少小鼠中的淀粉样 β (Aβ) 负荷。Thiethylperazine 具有抗精神病,止吐和抗菌作用。 |