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Search Results for " phenazine "

27

抑制剂 & 化合物

4

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T8138	Phenazine methylsulfate 5-甲基吩嗪硫酸甲酯,Phenazine methosulfate	Apoptosis; Antibacterial; Antibiotic	Apoptosis; Microbiology/Virology
	Phenazine methylsulfate 是一种自由基产生剂。它已被用作细胞活力测定中的电子转移反应物。它在还原剂 NADPH 存在下诱导 ssDNA 断裂形成。它在碱性彗星试验和细胞凋亡中诱导氧化性 DNA 损伤。
T25942	Phenazine oxide
	Phenazine oxide is a Bactericide, Fungicide, and Wood Preservative.
T69381	Dechloro perphenazine
	Dechloro perphenazine is the dechlorinated analogue of Perphenazine (P291100), an D2 dopamine receptor antagonist; α-adrenergic receptor antagonist and σ-receptor agonist.
T10232	Acetophenazine dimaleate	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Acetophenazine dimaleate 是抗精神病试剂，能够有效治疗焦虑抑郁。
T63115	Perphenazine dihydrochloride
	Perphenazine dihydrochloride 是一种口服具有活力的多巴胺受体 (dopamine receptor) 和组胺-1 受体 (histamine-1 receptor) 拮抗剂，作用于 D2 (Ki: 0.56 nM)、D3 (Ki: 0.43 nM)、5-HT2A (Ki: 0.6 nM)。Perphenazine dihydrochloride 也能够结合 Alpha-1A 肾上腺素受体。Perphenazine dihydrochloride 能够诱导细胞凋亡，并抑制癌细胞增殖。Perphenazine dihydrochloride 能够用于研究精神疾病、癌症、炎症。
T0068	Fluphenazine dihydrochloride 氟奋乃静盐酸盐,Prolixin,盐酸氟奋乃静,Fluphenazine hydrochloride	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Fluphenazine dihydrochloride (Prolixin) 是一种多巴胺受体D1/D2抑制剂。
T60195	Acetophenazine	Others	Others
	Acetophenazine 是一种抗焦虑化合物，可用于研究抑郁症。
T7943	Fluphenazine decanoate	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Fluphenazine decanoate 是一种高度连续的多巴胺 D2受体阻滞剂，是一种长效吩噻嗪抗精神病药，用于精神分裂症的研究。
T1090	Perphenazine Perphenazin,Etaperazine,Trilafon,奋乃静	CaMK; Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Perphenazine (Trilafon) 是吩噻嗪衍生物和多巴胺拮抗剂，具有止吐和抗精神病特性。它能够抑制5-HT2A 受体，α1A 肾上腺素能受体，多巴胺D2、D3、D2L 受体，以及组胺H1受体，对应的Ki 值分别为5.6、10、0.765、0.13、3.4 和 8 nM。
T83409	2,3-Diaminophenazine 2,3-Phenazinediamine
	2,3-Diaminophenazine (2,3-Phenazinediamine)，一种吩嗪的氨基化合物，广泛用于发光、电化学和生物化学领域的应用。
T64604	5,10-Di(naphthalen-2-yl)-5,10-dihydrophenazine
	5,10-Di(naphthalen-2-yl)-5,10-dihydrophenazine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64604。
T70288	Methophenazine diethanesulfonate
	Methophenazine diethanesulfonate is a Calmodulin antagonist.
T0068L	Fluphenazine Decanoate Dihydrochloride
	Fluphenazine Decanoate Dihydrochloride is an antipsychotic agent, it could block postsynaptic dopamine D2 receptors in the limbic, cortical system and basal ganglia.
T125045	Methyl 1-phenazinecarboxylate
	Methyl 1-phenazinecarboxylate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125045，CAS号为 3225-19-2。
T30753	Carphenazine Dimaleate Procethazine dimaleate,Proketazine maleate,Proketazine,carphenazine maleate,Proketazine dimaleate
	Carphenazine is used for the treatment of chronic schizophrenia, which is an antipsychotic agent.
T11304	Fluphenazine enanthate	Others	Others
	Fluphenazine enanthate is a novel long-acting injectable (LAI) antipsychotic compound specifically designed for the treatment of schizophrenia.
T36820	Fluphenazine-N-2-chloroethane (hydrochloride)
	Fluphenazine is a traditional antipsychotic compound that tightly binds the dopamine D2 receptor (Ki = 0.55 nM) and also reversibly inhibits calmodulin at micromolar concentrations. Fluphenazine-N-2-chloroethane is a derivative of fluphenazine that contains an alkylating chlorethylamine chain, which produces irreversible protein binding. It is a relatively selective, irreversible antagonist of D2 receptors both in vitro (IC50 = 100 nM) and in vivo, inactivating approximately 90% of D2 receptors ...
T0068L2	Fluphenazine free base Siqualine,Fluphenazine,Fluorophenazine,Fluorphenazine,Triflumethazine,Fluorfenazine
	Flufenazine is an antipsychotic drug. It is used to treat chronic mental illnesses such as schizophrenia. Flufenazine works by blocking postsynaptic dopamine D2 receptors in the limbic system, cortical system, and basal ganglia. This prevents the effects
TMIH-0428	Perphenazine-d8 2HCl
	Perphenazine-d8 2HCl 是 Perphenazine 2HCl 的氘代化合物。Perphenazine 2HCl 的 CAS 号为 2015-28-3。
TMIH-0241	Fluphenazine-d8 Dihydrochloride
	Fluphenazine-d8 Dihydrochloride 是 Fluphenazine Dihydrochloride 的氘代化合物。Fluphenazine Dihydrochloride 的 CAS 号为 146-56-5。Fluphenazine hydrochloride 是一种多巴胺受体D1/D2抑制剂。
T12411	Perphenazine D8 Dihydrochloride	Others	Others
	Perphenazine D8 Dihydrochloride is the deuterium labeled Perphenazine, which is an antipsychotic drug.
T0377	Clofazimine NSC-141046,氯法齐明,氯苯吩嗪	DNA; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Clofazimine (NSC-141046) 是一种具有显著的抗炎效果的亚氨基酚嗪类染料，与其它抗分支杆菌药物联用来治疗AIDS 和克罗恩病。
T80849	VU661
	VU661, 一种吩嗪甲酰胺类化合物，作为昼夜节律调节剂能促使昼夜节律周期延长，该小分子具备氧化还原活性。
T20233	Dibenzopyrazine AI3-00065,AI300065,AI3 00065
	Phenazine is a dibenzo annulated pyrazine and the parent substance of many dyestuffs.
T28311	PD 116152 PD116,152,PD 116,152,PD116152,PD-116,152,PD-116152
	PD 116152 is a highly substituted phenazine with antitumor activity isolated from the culture broth of a Streptomyces sp. The antitumor activity versus murine P388 leukemia is T/C 149. PD 116152 is selectively active versus the bacterium Streptococcus pne
T78446	Phenosafranine
	Phenosafranine是一种吩嗪染料，具有较高的三链RNA结合亲和力，相较于双链RNA。该染料通过嵌入机制与这两种RNA结合。Phenosafranine用途包括植物细胞染色，以及血红蛋白、多巴胺、血清素等的检测。
T77235	Methylene Violet 3RAX
	Methylene Violet 3RAX 是一种吩嗪染料，用于染色细胞的线粒体。Methylene Violet 3RAX 可以改变DNA 的分子结构，破坏DNA 的模块，诱导活性单线态氧的产生。Methylene Violet 3RAX 对人红细胞AChE 和人血浆BChE 具有抑制作用，Kis 分别为 1.58 和 0.51 μM。Methylene Violet 3RAX 具有研究PDT (光动力疗法) 中线粒体靶向作用的潜在光敏剂的潜力。

化合物

Phenazine methylsulfate

Cat.No: T8138

Synonym: 5-甲基吩嗪硫酸甲酯,Phenazine methosulfate

Target: Apoptosis, Antibacterial, Antibiotic

Phenazine oxide

Cat.No: T25942

Dechloro perphenazine

Cat.No: T69381

Acetophenazine dimaleate

Cat.No: T10232

Target: Dopamine Receptor

Perphenazine dihydrochloride

Cat.No: T63115

Fluphenazine dihydrochloride

Cat.No: T0068

Synonym: 氟奋乃静盐酸盐,Prolixin,盐酸氟奋乃静,Fluphenazine hydrochloride

Target: Dopamine Receptor

Cat.No: T60195

Target: Others

Fluphenazine decanoate

Cat.No: T7943

Target: Dopamine Receptor

Cat.No: T1090

Synonym: Perphenazin,Etaperazine,Trilafon,奋乃静

Target: CaMK, Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Histamine Receptor

2,3-Diaminophenazine

Cat.No: T83409

Synonym: 2,3-Phenazinediamine

5,10-Di(naphthalen-2-yl)-5,10-dihydrophenazine

Cat.No: T64604

Methophenazine diethanesulfonate

Cat.No: T70288

Fluphenazine Decanoate Dihydrochloride

Cat.No: T0068L

Methyl 1-phenazinecarboxylate

Cat.No: T125045

Carphenazine Dimaleate

Cat.No: T30753

Synonym: Procethazine dimaleate,Proketazine maleate,Proketazine,carphenazine maleate,Proketazine dimaleate

Fluphenazine enanthate

Cat.No: T11304

Target: Others

Fluphenazine-N-2-chloroethane (hydrochloride)

Cat.No: T36820

Fluphenazine free base

Cat.No: T0068L2

Synonym: Siqualine,Fluphenazine,Fluorophenazine,Fluorphenazine,Triflumethazine,Fluorfenazine

Perphenazine-d8 2HCl

Cat.No: TMIH-0428

Fluphenazine-d8 Dihydrochloride

Cat.No: TMIH-0241

Perphenazine D8 Dihydrochloride

Cat.No: T12411

Target: Others

Cat.No: T0377

Synonym: NSC-141046,氯法齐明,氯苯吩嗪

Target: DNA, Antibacterial, Antibiotic

Cat.No: T80849

Dibenzopyrazine

Cat.No: T20233

Synonym: AI3-00065,AI300065,AI3 00065

Cat.No: T28311

Synonym: PD116,152,PD 116,152,PD116152,PD-116,152,PD-116152

Cat.No: T78446

Methylene Violet 3RAX

Cat.No: T77235

Cat. No.	Product Name	Target	Signaling Pathways
TN7105	Phenazine-1-carboxylic acid	Antifungal	Microbiology/Virology
	Phenazine-1-carboxy acid 对所有植物病原真菌均显示出很强的抗真菌活性，抑制真菌生长约 90-100%。
T37009	Oxychlororaphine 吩嗪-1-甲酰胺,phenazine-1-carboxamide	Antibacterial	Microbiology/Virology
	Oxychlororaphine (phenazine-1-carboxamide) 强烈抑制 Streptomyces sp. 411 的生长。
T15417	Griseoluteic acid	Others	Others
	Griseoluteic acid is a breakdown product of griseolutein A and B. Griseoluteic acid is a phenazine antibiotic and is originally isolated from S. griseoluteus.
TN3616	Cedrelone	Apoptosis; MMP; Antifection	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Cedrelone 是一种柠檬苦素类化合物，是一种吩嗪生物合成样结构域蛋白 (PBLD) 激活剂。Cedrelone 可诱导癌细胞凋亡 (apoptosis)。Cedrelone 是一种非常有效的细胞凋亡诱导剂，它能导致细胞周期停止。Cedrelone 具有杀虫活性，可抑制 P. saucia 的箭毒生长，并可抑制乳草蝽（Oncopeltus fasciatus）的蜕皮。Cedrelone具有抗肿瘤作用，对SMMC-7721、A-549、MCF-7 和 SW480 等癌细胞株具有显著的细胞毒性。

天然产物

Phenazine-1-carboxylic acid

Cat.No: TN7105

Target: Antifungal

Oxychlororaphine

Cat.No: T37009

Synonym: 吩嗪-1-甲酰胺,phenazine-1-carboxamide

Target: Antibacterial

Griseoluteic acid

Cat.No: T15417

Target: Others

Cat.No: TN3616

Target: Apoptosis, MMP, Antifection

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