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Cat. No.	Product Name	Target	Signaling Pathways
T13824	PP58	FGFR; p38 MAPK; TNF; PDGFR; Src	Angiogenesis; Apoptosis; MAPK; Tyrosine Kinase/Adaptors
	PP58 是 PDGFR、FGFR 和 Src 家族的抑制剂。
T2414	Torkinib PP 242	Apoptosis; Mitophagy; PI3K; mTOR; Autophagy	Apoptosis; Autophagy; PI3K/Akt/mTOR signaling
	Torkinib (PP 242) 是一种选择性，ATP 竞争型的mTOR 抑制剂，IC50为 8 nM。它也抑制mTORC1和mTORC2，IC50分别为 30 nM 和 58 nM。
T71933	GNE-3500
	GNE-3500 is a Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C (RORc or RORγ) Inverse Agonist. Retinoic acid receptor-related orphan receptor C (RORc, RORγ, or NR1F3) is a nuclear receptor that plays a major role in the production of interleukin (IL)-17. Considerable efforts have been directed toward the discovery of selective RORc inverse agonists as potential treatments of inflammatory diseases such as psoriasis and rheumatoid arthritis. GNE-3500 poss...