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Targets Recommended: PAI-1 PAI-1 Apoptosis

33

抑制剂 & 化合物

4

天然产物

3

化合物库

6

TargetMol 试剂盒

32

重组蛋白

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Cat. No.	Product Name
L3980	DNA损伤/修复库Plus		667 compounds
	667 种 DNA 损伤/修复靶向、结构新颖的化合物；
L3900	DNA 损伤和修复分子库		910 compounds
	910 个与 DNA 损伤和修复紧密相关的化合物集合，是高通量筛选，高内涵筛选的良好载体；
L4020	NO PAINS 化合物库		9384 compounds
	TargetMol NO PAINS 化合物库包含 9384 个剔除了PAINS 的小分子活性化合物，可用于新药研发，信号通路研究，老药新用等研究。

化合物库

DNA损伤/修复库Plus

Cat.No: L3980

Compounds: 667

DNA 损伤和修复分子库

Cat.No: L3900

Compounds: 910

NO PAINS 化合物库

Cat.No: L4020

Compounds: 9384

Cat. No.	Product Name	Form	Specificity Of Inhibition
CEPY-0004	Human Cystatin S/CST4 ELISA Pair Set Human Cystatin S/CST4 ELISA 抗体对
CEPY-0001	Human Cystatin 7/CST7 ELISA Pair Set Human Cystatin 7/CST7 ELISA 抗体对
CEPY-0005	Human Cystatin SA/CST2 ELISA Pair Set Human Cystatin SA/CST2 ELISA 抗体对
CEPY-0002	Human Cystatin E/CST6 ELISA Pair Set Human Cystatin E/CST6 ELISA 抗体对
CEPY-0006	Human Cystatin SN/CST1 ELISA Pair Set Human Cystatin SN/CST1 ELISA 抗体对
CEPY-0003	Human Cystatin C/CST3 ELISA Pair Set Human Cystatin C/CST3 ELISA 抗体对

TargetMol 试剂盒

Human Cystatin S/CST4 ELISA 抗体对

Cat.No: CEPY-0004

Human Cystatin 7/CST7 ELISA 抗体对

Cat.No: CEPY-0001

Human Cystatin SA/CST2 ELISA 抗体对

Cat.No: CEPY-0005

Human Cystatin E/CST6 ELISA 抗体对

Cat.No: CEPY-0002

Human Cystatin SN/CST1 ELISA 抗体对

Cat.No: CEPY-0006

Human Cystatin C/CST3 ELISA 抗体对

Cat.No: CEPY-0003

Cat. No.	Product Name	Target	Signaling Pathways
T2030	Tiplaxtinin PAI-039,Tiplasinin	PAI-1; Apoptosis	Apoptosis; Metabolism
	Tiplaxtinin (Tiplasinin) 是一种具有口服活性的选择性纤溶酶原激活物抑制剂-1 抑制剂，IC50为 2.7 μM。
T25915	Diaplasinin PAI-749,PAI749,PAI 749
	PAI-749 is a selective and effective antagonist agent of plasminogen activator inhibitor 1 (PAI-1).
T13252	(S)-Rasagiline TVP1022,(S)-雷沙吉兰,S-PAI	Others	Others
	(S)-Rasagiline is rasagiline S-isomer, and is an agent of anti-Parkinson.
T13252L	(S)-Rasagiline mesylate TVP1022 (mesylate),(S)-雷沙吉兰甲磺酸,S-PAI mesylate	Others	Others
	(S)-Rasagiline mesylate is rasagiline S-isomer, and is an agent of anti-Parkinson.
T28788	SK-216 SK216.Plasminogen activator inhibitor-1 (PAI-1) inhibitor
	SK-216 is a specific PAI-1 inhibitor. SK-216 reduced the extent of angiogenesis in the tumors and inhibited VEGF-induced migration and tube formation by human umbilical vein endothelial cells in vitro. SK-216 reduced the degree of bleomycin-induced pulmon
T8962	TM5007	PAI-1	Metabolism
	TM5007 是纤溶酶原激活物抑制剂-1（PAI-1；IC50 为 29 uM）的强效抑制剂。
T4254	TM5441	PAI-1; Apoptosis	Apoptosis; Metabolism
	TM5441 是口服生物可利用的纤溶酶原激活物抑制剂-1 抑制剂，抑制多个癌症细胞系的 IC50值在 13.9 到 51.1 μM。它诱导几种人类癌症细胞的内在调亡，减弱 Nω-硝基-1-精氨酸甲酯诱导的心脏高血压和血管衰老。
T3442	UK-371804 UK371804	PAI-1; Serine Protease	Metabolism; Proteases/Proteasome
	UK-371804 是一种尿嘧啶型纤溶酶原激活物的抑制剂，Ki=10 nM。
T13257	Upamostat	PAI-1; Serine/threonin kinase; Serine Protease	Cell Cycle/Checkpoint; Metabolism; Proteases/Proteasome
	Upamostat 是一种丝氨酸蛋白酶抑制剂，也是一种具有口服活性的 WX-UK1 前药，是一种尿激酶型纤溶酶原激活剂 (uPA) 抑制剂。
T4255	TM5275 sodium TM5275 sodium salt	PAI-1	Metabolism
	TM5275 sodium (TM5275 sodium salt) 是一种纤溶酶原激活物抑制剂，IC50=6.95 μM。
T13408	ZK824190	Others; Serine Protease	Others; Proteases/Proteasome
	ZK824190 是具有口服活性尿激酶型纤溶酶原激活剂 (uPA) 选择性抑制剂，对 uPA，tPA 和 Plasmin 的IC50分别为 237，1600 和 1850 nM。ZK824190在多发性硬化症中有研究价值。
T29856	Aleplasinin PAZ 417,PAZ417,PAZ-417	PAI-1	Metabolism
	Aleplasinin (PAZ 417) 是纤溶酶原激活物抑制剂 1 (PAI-1) 的选择性和口服活性抑制剂，是纤溶系统的关键负调节剂。 Aleplasinin 可用于阿尔茨海默病研究。
T26637	Antipain dihydrochloride Antipain 2HCl,BDBM-32804,BDBM 32804, Antipain,BDBM32804	Protease	Proteases/Proteasome
	Antipain dihydrochloride (Antipain 2HCl) 是一种从 Actinomycetes 提取到的蛋白酶抑制剂，具有镇痛活性，抑制 X 射线诱导的人淋巴细胞染色体畸变。
T21521L	Papain Inhibitor acetate 乙氨酸-乙氨酸-酪氨酸-精氨酸,GGYR,Gly-Gly-Tyr-Arg,Papain Inhibitor acetate （70195-20-9 free base)	Others	Others
	Papain Inhibitor acetate (Gly-Gly-Tyr-Arg) 是木瓜蛋白酶的亲和配体。
T61634	Falcipain-2/3-IN-2
	Falcipain-2/3-IN-2 (Compound 12) 是一种falcipain-2和falcipain-3的双重抑制剂。
T80551	Calpain inhibitor V Mu-Val-HPh-FMK	Antibiotic	Microbiology/Virology
	Calpain inhibitor V (Mu-Val-HPh-FMK) 为具抗衣原体活性的细胞渗透性不可逆钙蛋白酶抑制剂。
T63391	Calpain Inhibitor-2
	Calpain Inhibitor-2 是具有亲脂性的钙蛋白酶抑制剂，与黑色素瘤细胞系（A-375和B-16F1）和PC-3前列腺癌细胞相比，他们在体外具有中等到良好的抗增殖效果。Calpain Inhibitor-2 中的化合物3，在基质胶细胞侵袭测定中以2μM 浓度能够抑制了80%的DU-145细胞侵袭。
T14295	Antipain	Others	Others
	Antipain is a protease inhibitor isolated from Actinomycetes. Antipain inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations[1][2].
T33578	Naepaine hydrochloride
	Naepaine hydrochloride is a biochemical.
T76145	Clostripain
	Clostripain(Clostridiopeptidase B)为源自Clostridium histolyticum的蛋白质水解酶，展现酯酶、酰胺酶及蛋白酶活性，特异性高，针对精氨酸羧基肽键。
T72439	Calpain Inhibitor XI
	Calpain Inhibitor XI，一种可逆的calpain-1共价抑制剂，适用于神经退行性疾病的研究。
T38931	Calpain Inhibitor-1
	Calpain Inhibitor-1 (compound 36) is a highly potent and selective inhibitor of Calpain 1 (Cal1), which is a cysteine protease. It exhibits an IC50 value of 100 nM and a Ki value of 2.89 μM.
T64183	PAIR2
	PAIR2 是一种有效和选择性的 IRE1α RNase 的部分拮抗剂。PAIR2 可以完全占据细胞中 IRE1α 的 ATP 结合位点，并阻断强效 KIRA 抑制 XBP1 剪接的能力。
T21949	Calpain Inhibitor XII
	(Rac)-Calpain Inhibitor XII是一种可逆的，选择性抑制钙蛋白酶I（calpain I; μ-calpain）的化合物，具有19 nM的Ki值。其对钙蛋白酶II（calpain II; m-calpain; Ki=120 nM）和组织蛋白酶B（cathepsin B; Ki=750 nM）显示出较低的抑制亲和力。(Rac)-Calpain Inhibitor XII用于研究钙蛋白酶在多种生理过程中的角色，如嗜中性粒细胞趋化性、神经元信号传导和心脏对损伤的响应。
T63708	Calpain-2-IN-1
	Calpain-2-IN-1是选择性的钙蛋白酶-2抑制剂，能够延长 ERK 激活，进而增强学习和记忆。
T76374	SPAI-1
	SPAI-1，特异性单价阳离子ATP酶抑制剂，源自猪十二指肠。能体外抑制Na+，K+-ATP酶和H+，K+-ATP酶，同时刺激Mg2+-ATP酶。
T10685L	Carpaine hydrochloride	Others	Others
	Carpaine hydrochloride, an alkaloid isolated from Carica papaya Linn, has anti-thrombocytopenic activity. It has the anti-plasmodial activity to prevent malaria.
T23764	AZ3976 AZ 3976,AZ-3976	PAI-1	Metabolism
	AZ3976 是一种纤溶酶原激活物抑制剂-1抑制剂，在血浆凝块溶解试验中的 IC50为16μM。AZ3976 显示促纤维蛋白溶解活性。
T25217	CDE-096
	CDE-096 is a plasminogenactivator inhibitor-1 (PAI-1) inactivator.
T68572	IMD-1622
	IMD-1622 is a plasminogen activator inhibitor-1 (PAI-1) inhibitor.
T70810	THR-18
	THR-18 is an 18-mer peptide derived from the sequence of human plasminogen activator inhibitor 1 (PAI-1), having the ability to bind to a site of tissue plasminogen activator (tPA) distal to its catalytic site and uncouple the beneficial clot-dissolving properties of tPA from its deleterious non-fibrinolytic effects.
T22343	HKB99	Others	Others
	HKB99 是磷酸甘油酸突变酶 1 (PGAM1) 的突变抑制剂。HKB99可增加氧化应激，激活JNK/c-Jun，抑制AKT和ERK[1]。HKB99可抑制侵袭性假栓的形成，提高PAI-2的水平，可用于非小细胞肺癌（NSCLC）的研究[2]。
T35520	Aflatoxin G1-13C17 Aflatoxin G1-13C17
	Aflatoxin G1-13C17is intended for use as an internal standard for the quantification of aflatoxin G1by GC- or LC-MS. Aflatoxin G1is a mycotoxin that has been found inA. terricola.1In vivo, aflatoxin G1is lethal to ducklings (LD50= 1.18 mg/kg).2It induces hepatocellular carcinoma tumor formation and lethality in rats when administered at doses of 1.4 and 3 mg/animal, respectively. Aflatoxin G1also inhibits liver and kidney succinate dehydrogenase and fumarase, as well as kidney cytochrome oxidase...

化合物

Cat.No: T2030

Synonym: PAI-039,Tiplasinin

Target: PAI-1, Apoptosis

Cat.No: T25915

Synonym: PAI-749,PAI749,PAI 749

Cat.No: T13252

Synonym: TVP1022,(S)-雷沙吉兰,S-PAI

Target: Others

(S)-Rasagiline mesylate

Cat.No: T13252L

Synonym: TVP1022 (mesylate),(S)-雷沙吉兰甲磺酸,S-PAI mesylate

Target: Others

Cat.No: T28788

Synonym: SK216.Plasminogen activator inhibitor-1 (PAI-1) inhibitor

Cat.No: T8962

Target: PAI-1

Cat.No: T4254

Target: PAI-1, Apoptosis

Cat.No: T3442

Synonym: UK371804

Target: PAI-1, Serine Protease

Cat.No: T13257

Target: PAI-1, Serine/threonin kinase, Serine Protease

Cat.No: T4255

Synonym: TM5275 sodium salt

Target: PAI-1

Cat.No: T13408

Target: Others, Serine Protease

Cat.No: T29856

Synonym: PAZ 417,PAZ417,PAZ-417

Target: PAI-1

Antipain dihydrochloride

Cat.No: T26637

Synonym: Antipain 2HCl,BDBM-32804,BDBM 32804, Antipain,BDBM32804

Target: Protease

Papain Inhibitor acetate

Cat.No: T21521L

Synonym: 乙氨酸-乙氨酸-酪氨酸-精氨酸,GGYR,Gly-Gly-Tyr-Arg,Papain Inhibitor acetate （70195-20-9 free base)

Target: Others

Falcipain-2/3-IN-2

Cat.No: T61634

Calpain inhibitor V

Cat.No: T80551

Synonym: Mu-Val-HPh-FMK

Target: Antibiotic

Calpain Inhibitor-2

Cat.No: T63391

Cat.No: T14295

Target: Others

Naepaine hydrochloride

Cat.No: T33578

Cat.No: T76145

Calpain Inhibitor XI

Cat.No: T72439

Calpain Inhibitor-1

Cat.No: T38931

Cat.No: T64183

Calpain Inhibitor XII

Cat.No: T21949

Cat.No: T63708

Cat.No: T76374

Carpaine hydrochloride

Cat.No: T10685L

Target: Others

Cat.No: T23764

Synonym: AZ 3976,AZ-3976

Target: PAI-1

Cat.No: T25217

Cat.No: T68572

Cat.No: T70810

Cat.No: T22343

Target: Others

Aflatoxin G1-13C17

Cat.No: T35520

Synonym: Aflatoxin G1-13C17

Cat. No.	Product Name	Target	Signaling Pathways
T3876	Loureirin B 龙血素B,龙血素 B	PAI-1; ERK; Potassium Channel; JNK	MAPK; Membrane transporter/Ion channel; Metabolism
	Loureirin B 是从剑叶龙血树中分离到的一种黄酮，是 PAI-1抑制剂，IC50值为 26.10 μM。它抑制 KATP，以及 ERK 和 JNK 的磷酸化，具有抗糖尿病的功效。
T4S0592	Toddalolactone (+)-Toddalolactone,飞龙掌血内酯,毛两面针素	PAI-1	Metabolism
	Toddalolactone ((+)-Toddalolactone) 是一种Toddalia asiatica 的主要成分，能够抑制重组人纤溶酶原激活物抑制物-1(PAI-1)的活性， IC50=37.31 μM。
T19503	Papain	Others; Cysteine Protease	Others; Proteases/Proteasome
	Papain 是一种半胱氨酸蛋白酶，是肽酶 C1 家族中一员，在食品、医药、化妆品、纺织等具有广泛的应用。
T10685	Carpaine	Others	Others
	Carpaine, an alkaloid isolated from Carica papaya Linn, has anti-thrombocytopenic activity. It has the anti-plasmodial activity to prevent malaria.

天然产物

Cat.No: T3876

Synonym: 龙血素B,龙血素 B

Target: PAI-1, ERK, Potassium Channel, JNK

Cat.No: T4S0592

Synonym: (+)-Toddalolactone,飞龙掌血内酯,毛两面针素

Target: PAI-1

Cat.No: T19503

Target: Others, Cysteine Protease

Cat.No: T10685

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01474	PAI-1 Protein, Human, Recombinant (His) PAI,SERPINE1,PAI-1,serpin peptidase inhibi...	Human	HEK293 Cells
	PAI-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.2 kDa and the accession number is A0A024QYT5.
TMPY-01711	Serpin B2 Protein, Human, Recombinant (GST) PAI,serpin peptidase inhibitor, clade B (ovalbumin)...	Human	Baculovirus Insect Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner.SerpinB2, also known as Plasminogen activator inhibitor 2, Placental plasminogen activator inhibitor, Monocyte Arg-serpin, Urokinase inhibitor and PAI2, is a cytoplasm protein that belongs to the serpin fa...
TMPH-00833	PAI-1 Protein, Horse, Recombinant	Horse	P. pastoris (Yeast)
	PAI-1 Protein, Horse, Recombinant is expressed in yeast. The predicted molecular weight is 36.2 kDa and the accession number is Q8MI31.
TMPH-00356	PAI-1 Protein, Feline, Recombinant	Feline	E. coli
	PAI-1 Protein, Feline, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 29.7 kDa and the accession number is A9NJ78.
TMPY-00629	PAI-1 Protein, Rat, Recombinant (hFc) serpin peptidase inhibitor, clade E (nexin, plasminogen acti...	Rat	HEK293 Cells
	PAI-1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 69.6 kDa and the accession number is A6J047.
TMPY-02559	PAI-1 Protein, Rat, Recombinant (His) serpin peptidase inhibitor, clade E (nexin, plasminogen acti...	Rat	HEK293 Cells
	PAI-1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.2 kDa and the accession number is A6J047.
TMPH-01869	PAI-2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. PAI-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis tag. The predicted molecular weight is 50.1 kDa and the accession number is P05120.
TMPH-02833	PAI-1 Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	PAI-1 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 44.9 kDa and the accession number is P22777.
TMPH-02834	PAI-1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of ...
TMPH-00832	PAI-1 Protein, Horse, Recombinant (E. coli)	Horse	E. coli
	PAI-1 Protein, Horse, Recombinant (E. coli) is expressed in E. coli expression system. The predicted molecular weight is 32.1 kDa and the accession number is Q8MI31.
TMPJ-00490	Serpin A5 Protein, Human, Recombinant (His) Plasminogen Activator Inhibitor 3,Acrosomal Serine Protease ...	Human	HEK293 Cells
	Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent inhibitor of the protein C anticoagulant pathway at the levels of both zymogen activation and enzyme inhibition, Serpin A5 additionally inhibits a variety of serine protease including thrombin, factor Xa, several kallekreins and acrosin. It plays a critical role in the processes o...
TMPH-03648	Cruzipain Protein, Trypanosoma cruzi, Recombinant (His & Myc) Cruzaine,Cruzipain,Major cysteine proteinase	Trypanosoma cruzi	E. coli
	Hydrolyzes chromogenic peptides at the carboxyl Arg or Lys; requires at least one more amino acid, preferably Arg, Phe, Val or Leu, between the terminal Arg or Lys and the amino-blocking group.; The cysteine protease may play an important role in the development and differentiation of the parasites at several stages of their life cycle. Cruzipain Protein, Trypanosoma cruzi, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weig...
TMPY-05892	Influenza A H3N2 (A/swine/Spain/33601/2001) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	H3N2	HEK293 Cells
	Influenza A H3N2 (A/swine/Spain/33601/2001) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.8 kDa and the accession number is Q288R9.
TMPY-05945	Influenza A H1N2 (A/Swine/Spain/SF12091/2007) Neuraminidase/NA Protein (His)	H1N2	HEK293 Cells
	Influenza A H1N2 (A/Swine/Spain/SF12091/2007) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.6 kDa and the accession number is R4ZD61.
TMPY-05682	SARS-CoV-2 Plpro/papain-like protease Protein (aa 1564-1880, His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Plpro/papain-like protease Protein (aa 1564-1880, His) is expressed in E. coli expression system. The predicted molecular weight is 36.79 kDa and the accession number is QVD65746.1.
TMPH-03151	Gingipain R1 Protein, Porphyromonas gingivalis, Recombinant (His)	Porphyromonas gingivalis	P. pastoris (Yeast)
	Thiol protease. Acts synergistically with RgpB to catalyze the maturation of fimbrial subunits, such as FimA. Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms (Probable). Gingipain R1 Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 56.0 kDa and the accession number is P28784.
TMPY-04894	SARS-CoV (strain WH20) Plpro/papain-like protease (His)	SARS	E. coli
	SARS-CoV (strain WH20) Plpro/papain-like protease (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 36.65 kDa and the accession number is AAX16193.1.
TMPH-03576	Staphopain A Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Staphopain A Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.4 kDa and the accession number is P81297.
TMPJ-01431	SARS-CoV-2 Papain-Like Protease Protein PLpro,PL-PRO,pp1a,Replicase polyprotein 1a,Papain-l...	SARS-CoV-2	E. coli
	Replication of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) requires proteolytic processing of the replicase polyprotein by two viral cysteine proteases, a chymotrypsin-like protease (3CLpro) and a papain-like protease (PLpro). These proteases are important targets for development of antiviral drugs that would inhibit viral replication and reduce mortality associated with outbreaks of SARS-CoV. PLpro is a cysteine protease located within the non-structural protein 3 (NS3) sect...
TMPK-01352	SARS-CoV-2 PLpro/papain-like protease Protein (His & Avi) Plpro,PL2-PRO,pp1a,nsp1,Replicase polyprotein 1a,Papai	SARS	E. coli
	The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. SARS-CoV-2 PLpro/papain-like protease Pro...
TMPK-01384	SARS PLpro/papain-like protease Protein (His) Papain-like Protease,PL-PRO,Replicase polyprotein 1...	SARS	E. coli
	The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. SARS PLpro/papain-like protease Protein (...
TMPH-02414	Lys-gingipain W83 Protein, Porphyromonas gingivalis, Recombinant (His)	Porphyromonas gingivalis	E. coli
	Lys-gingipain W83 Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in E. coli expression system with C-10xHis tag. The predicted molecular weight is 51.6 kDa and the accession number is Q51817.
TMPH-03154	Lys-gingipain 381 Protein, Porphyromonas gingivalis, Recombinant (His)	Porphyromonas gingivalis	E. coli
	Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria. Lys-gingipain 381 Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in E. coli e...
TMPH-03577	Staphopain B Protein, S. aureus, Recombinant (GST)	Staphylococcus aureus	E. coli
	Cysteine protease that plays an important role in the inhibition of host innate immune response. Degrades host elastin, fibrogen, fibronectin and kininogen. Blocks phagocytosis of opsonised S. aureus by neutrophils and monocytes by inducing their death in a proteolytic activity-dependent manner. Decreases surface expression of the 'don't eat me' signal CD31 on neutrophils. Cleaves host galectin-3/LGALS3, thereby inhibiting the neutrophil-activating ability of the lectin. Staphopain B Protein, S....
TMPH-03599	Streptopain Protein, S. pyogenes, Recombinant (His & SUMO)	Streptococcus pyogenes	E. coli
	Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing. Streptopain Protein, S. pyogenes, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO...
TMPH-03155	Lys-gingipain HG66 Protein, Porphyromonas gingivalis, Recombinant (His & Myc)	Porphyromonas gingivalis	E. coli
	Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria. Lys-gingipain HG66 Protein, Porphyromonas gingivalis, Recombinant (His & Myc) is expressed in E....
TMPH-03153	Gingipain R2 Protein, Porphyromonas gingivalis, Recombinant (His)	Porphyromonas gingivalis	E. coli
	Thiol protease. Acts synergistically with RgpA to catalyze the maturation of fimbrial subunits, such as FimA. Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms. Gingipain R2 Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in E. coli expression system with C-10xHis tag. The predicted molecular weight is 57.1 kDa and the accession number is P95493.
TMPH-03598	Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO)	Streptococcus pyogenes	E. coli
	Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing. Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO) is expressed in E. coli expression system with...
TMPH-03152	Gingipain R1 Protein, Porphyromonas gingivalis, Recombinant (B2M & His)	Porphyromonas gingivalis	E. coli
	Thiol protease. Acts synergistically with RgpB to catalyze the maturation of fimbrial subunits, such as FimA. Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms (Probable). Gingipain R1 Protein, Porphyromonas gingivalis, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 68.0 kDa and the accession number is P28784.
TMPH-00347	Papain Protein, Carica papaya, Recombinant (His)	Carica papaya	E. coli
	Papain Protein, Carica papaya, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.4 kDa and the accession number is P00784.
TMPH-03156	Lys-gingipain Protein, Porphyromonas gingivalis, Recombinant (His & SUMO)	Porphyromonas gingivalis	E. coli
	Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria. Lys-gingipain Protein, Porphyromonas gingivalis, Recombinant (His & SUMO) is expressed in E. col...
TMPH-00528	Recombination and repair protein Protein, Enterobacteria phage T4, Recombinant (His)	Enterobacteria phage T4	E. coli
	Important in genetic recombination, DNA repair, and replication. Possesses pairing and strand-transfer activity. Interacts with dda and gene 32 proteins.

重组蛋白

PAI-1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01474

Species: Human

Expression System: HEK293 Cells

Serpin B2 Protein, Human, Recombinant (GST)

Cat.No: TMPY-01711

Species: Human

Expression System: Baculovirus Insect Cells

PAI-1 Protein, Horse, Recombinant

Cat.No: TMPH-00833

Species: Horse

Expression System: P. pastoris (Yeast)

PAI-1 Protein, Feline, Recombinant

Cat.No: TMPH-00356

Species: Feline

Expression System: E. coli

PAI-1 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-00629

Species: Rat

Expression System: HEK293 Cells

PAI-1 Protein, Rat, Recombinant (His)

Cat.No: TMPY-02559

Species: Rat

Expression System: HEK293 Cells

PAI-2 Protein, Human, Recombinant (His)

Cat.No: TMPH-01869

Species: Human

Expression System: HEK293 Cells

PAI-1 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02833

Species: Mouse

Expression System: P. pastoris (Yeast)

PAI-1 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02834

Species: Mouse

Expression System: E. coli

PAI-1 Protein, Horse, Recombinant (E. coli)

Cat.No: TMPH-00832

Species: Horse

Expression System: E. coli

Serpin A5 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00490

Species: Human

Expression System: HEK293 Cells

Cruzipain Protein, Trypanosoma cruzi, Recombinant (His & Myc)

Cat.No: TMPH-03648

Species: Trypanosoma cruzi

Expression System: E. coli

Influenza A H3N2 (A/swine/Spain/33601/2001) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-05892

Species: H3N2

Expression System: HEK293 Cells

Influenza A H1N2 (A/Swine/Spain/SF12091/2007) Neuraminidase/NA Protein (His)

Cat.No: TMPY-05945

Species: H1N2

Expression System: HEK293 Cells

SARS-CoV-2 Plpro/papain-like protease Protein (aa 1564-1880, His)

Cat.No: TMPY-05682

Species: SARS-CoV-2

Expression System: E. coli

Gingipain R1 Protein, Porphyromonas gingivalis, Recombinant (His)

Cat.No: TMPH-03151

Species: Porphyromonas gingivalis

Expression System: P. pastoris (Yeast)

SARS-CoV (strain WH20) Plpro/papain-like protease (His)

Cat.No: TMPY-04894

Species: SARS

Expression System: E. coli

Staphopain A Protein, S. aureus, Recombinant (His & Myc)

Cat.No: TMPH-03576

Species: Staphylococcus aureus

Expression System: E. coli

SARS-CoV-2 Papain-Like Protease Protein

Cat.No: TMPJ-01431

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 PLpro/papain-like protease Protein (His & Avi)

Cat.No: TMPK-01352

Species: SARS

Expression System: E. coli

SARS PLpro/papain-like protease Protein (His)

Cat.No: TMPK-01384

Species: SARS

Expression System: E. coli

Lys-gingipain W83 Protein, Porphyromonas gingivalis, Recombinant (His)

Cat.No: TMPH-02414

Species: Porphyromonas gingivalis

Expression System: E. coli

Lys-gingipain 381 Protein, Porphyromonas gingivalis, Recombinant (His)

Cat.No: TMPH-03154

Species: Porphyromonas gingivalis

Expression System: E. coli

Staphopain B Protein, S. aureus, Recombinant (GST)

Cat.No: TMPH-03577

Species: Staphylococcus aureus

Expression System: E. coli

Streptopain Protein, S. pyogenes, Recombinant (His & SUMO)

Cat.No: TMPH-03599

Species: Streptococcus pyogenes

Expression System: E. coli

Lys-gingipain HG66 Protein, Porphyromonas gingivalis, Recombinant (His & Myc)

Cat.No: TMPH-03155

Species: Porphyromonas gingivalis

Expression System: E. coli

Gingipain R2 Protein, Porphyromonas gingivalis, Recombinant (His)

Cat.No: TMPH-03153

Species: Porphyromonas gingivalis

Expression System: E. coli

Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO)

Cat.No: TMPH-03598

Species: Streptococcus pyogenes

Expression System: E. coli

Gingipain R1 Protein, Porphyromonas gingivalis, Recombinant (B2M & His)

Cat.No: TMPH-03152

Species: Porphyromonas gingivalis

Expression System: E. coli

Papain Protein, Carica papaya, Recombinant (His)

Cat.No: TMPH-00347

Species: Carica papaya

Expression System: E. coli

Lys-gingipain Protein, Porphyromonas gingivalis, Recombinant (His & SUMO)

Cat.No: TMPH-03156

Species: Porphyromonas gingivalis

Expression System: E. coli

Recombination and repair protein Protein, Enterobacteria phage T4, Recombinant (His)

Cat.No: TMPH-00528

Species: Enterobacteria phage T4

Expression System: E. coli

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