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Targets Recommended: Apoptosis Others DNA/RNA Synthesis

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抑制剂 & 化合物

11

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T9150 SCR130

1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-

Apoptosis; Others; DNA/RNA Synthesis Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂,可诱导细胞凋亡并,具有抗癌活性。 它特异性依赖连接酶 IV,抑制 DNA 的末端连接。
T6997 SU6656

FAK; Akt; Src Angiogenesis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
SU6656 是Src 家族激酶抑制剂,抑制 Src,Yes,Lyn,Fyn 的IC50分别为 280,20,130,170 nM。它还能抑制p-AKT。它可抑制FAK Y576/577、 Y925、Y861位点的磷酸化。
T38276 Benzomalvin C

Benzomalvin C is a weak antagonist of the neurokinin-1 (NK1) receptor inhibiting binding of substance P by 46% when used at 100 μg/ml in vitro. It is also a weak inhibitor of indolamine 2,3-dioxygenase (IDO) with an IC50 value of 130 μM for recombinant IDO. It was isolated from Penicillium and contains an epoxide group at C-19 and C-20, which is not present in benzomalvins A, B, or E.
T35680 2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide

2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is an antimicrobial agent.1It is active against the Gram-negative bacteriaE. coli,P. aeruginosa, andS. marcescens(MICs = 64, 100, and 70 μg/ml, respectively), the Gram-positive bacteriaS. aureus,M. luteus, andB. cereus(MICs = 130, 100, and 50 μg/ml, respectively), and the fungiC. albicans,G. candidum,T. rubrum,F. oxysporum,A. flavus, andS. brevicaulis(MICs = 69-120 μg/ml). 2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is also a prec...

化合物

SCR130
Cat.No: T9150
Synonym: 1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-
Target: Apoptosis, Others, DNA/RNA Synthesis
SU6656
Cat.No: T6997
Synonym:
Target: FAK, Akt, Src
Benzomalvin C
Cat.No: T38276
Synonym:
Target:
2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide
Cat.No: T35680
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPK-00947 CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated

CDH16,Cdh17,P130,cadherin-16,HPT-...

Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated...
TMPK-00952 CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc)

BILL-cadherin,Cadherin-17,LI-cadherin,CDH16,cadherin-16,Cdh1...

Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc) is exp...
TMPK-00951 CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

FLJ26931,CDH16,LI-cadherin,MGC138218,cadherin-16,Cadherin-17...

Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, R...
TMPK-00948 CDH17 Protein, Human, Recombinant (hFc)

Cdh17,cadherin-16,FLJ26931,Cadherin-17,HPT-1,P<...

Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Human, Recombinant (hFc) is expressed in HEK...
TMPK-00555 CDH17 Protein, Cynomolgus, Recombinant (His)

Cdh17,HPT-1,FLJ26931,LI-cadherin,BILL-cadherin,...

Cynomolgus HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Cynomolgus, Recombinant (His) is expressed i...
TMPK-00950 CDH17 Domain 6-7 Protein, Human, Recombinant (hFc)

HPT-1,P130,MGC138218,LI-cadherin,...

Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 6-7 Protein, Human, Recombinant (hFc) is expre...
TMPK-00473 CDH17 Protein, Rhesus macaque, Recombinant (His)

CDH16,Cdh17,MGC142024,Cadherin-17,cadherin-16,P...

Rhesus HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Rhesus macaque, Recombinant (His) is express...
TMPK-01223 CDH17 Protein, Mouse, Recombinant (His)

CDH16,LI-cadherin,Cdh17,MGC138218,HPT-1,MGC142024,F...

Mouse HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Mouse, Recombinant (His) is expressed in HEK...
TMPK-01224 CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated

P130,BILL-cadherin,LI-cadherin,MGC138218,F...

Mouse HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant ...
TMPK-00949 CDH17 Domain 7 Protein, Human, Recombinant (hFc)

CDH16,P130,MGC142024,Cdh17,FLJ26931,Cadher...

Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 7 Protein, Human, Recombinant (hFc) is express...
TMPK-00953 CDH17 Domain 6-7 Protein, Human, Recombinant (mFc)

Cdh17,CDH16,MGC138218,BILL-cadherin,HPT-1,cadherin-...

Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 6-7 Protein, Human, Recombinant (mFc) is expre...

重组蛋白

CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00947
Species: Human
Expression System: HEK293 Cells
CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc)
Cat.No: TMPK-00952
Species: Human
Expression System: HEK293 Cells
CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
Cat.No: TMPK-00951
Species: Human
Expression System: HEK293 Cells
CDH17 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00948
Species: Human
Expression System: HEK293 Cells
CDH17 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00555
Species: Cynomolgus
Expression System: HEK293 Cells
CDH17 Domain 6-7 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00950
Species: Human
Expression System: HEK293 Cells
CDH17 Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPK-00473
Species: Rhesus
Expression System: HEK293 Cells
CDH17 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01223
Species: Mouse
Expression System: HEK293 Cells
CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
Cat.No: TMPK-01224
Species: Mouse
Expression System: HEK293 Cells
CDH17 Domain 7 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00949
Species: Human
Expression System: HEK293 Cells
CDH17 Domain 6-7 Protein, Human, Recombinant (mFc)
Cat.No: TMPK-00953
Species: Human
Expression System: HEK293 Cells
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