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Cat. No.	Product Name	Target	Signaling Pathways
T0757	Omeprazole Losec,Prilosec,奥美拉唑,奥美拉挫,H 16868,Antra	Proton pump; Phospholipase; Antibacterial; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Omeprazole (Losec) 是一种质子泵抑制剂，有研究胃肠道疾病的潜力。它竞争性抑制 CYP2C19活性，Ki 为 2 到 6 μM。它还抑制革兰氏阳性菌和革兰氏阴性菌生长。它是中性鞘磷脂酶的外泌体抑制剂。
T12309	Omeprazole metabolite Omeprazole sulfone Omeprazole sulphone,Omeprazole sulfone	Others	Others
	Omeprazole metabolite Omeprazole sulfone 是Omeprazole 的代谢物，能够抑制质子泵。
T2687	Omeprazole sulfide Omeprazole metabolite Omeprazole sulfide,Ufiprazole,奥美拉唑硫醚	Proton pump; Drug Metabolite	Membrane transporter/Ion channel; Metabolism
	Omeprazole sulfide (Ufiprazole) 是 Omeprazole 的代谢物。
T10138	4-Desmethoxy Omeprazole	Drug Metabolite	Metabolism
	4-Desmethoxy Omeprazole 是 Omeprazole 的活性代谢物。Omeprazole 是质子泵抑制剂。Omeprazole 竞争性抑制 CYP2C19 活性，Ki=2 - 6 μM。Omeprazole 还抑制革兰氏阴性菌和革兰氏阳性菌生长。
T22391	Omeprazole Sodium	P450; Proton pump; Antibacterial; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Omeprazole 是有效的质子泵抑制剂，在胃肠道疾病的研究中具有价值。它竞争性抑制CYP2C19活性，Ki 为 2 到 6 μM。它还抑制革兰氏阴性菌和革兰氏阳性菌生长。它是中性鞘磷脂酶的外泌体抑制剂。
T2686	Esomeprazole Magnesium (S)-Omeprazole magnesium,NEXIUM,埃索美拉唑镁,(-)-Omeprazole magnesium	ATPase; Proton pump	Membrane transporter/Ion channel
	Esomeprazole Magnesium (NEXIUM) 是一种口服有效的 H+, K+-ATPase 抑制剂，在上消化道疾病和胃食管反流疾病中具有研究价值。Esomeprazole magnesium 是一种外泌体抑制剂，通过抑制 V-H+-ATPases 来阻断外泌体的释放。
T2686L	Esomeprazole Sodium 埃索美拉唑钠,(S)-Omeprazole sodium	ATPase; Proton pump	Membrane transporter/Ion channel
	Esomeprazole Sodium ((S)-Omeprazole sodium) 是一种口服有效的活性质子泵抑制剂。Esomeprazole sodium 通过抑制胃壁细胞中的 H+, K+-ATPase 来降低酸分泌，在胃食管反流疾病中有研究价值。Esomeprazole 是一种外泌体抑制剂，通过抑制 V-H+-ATPases 来阻断外泌体的释放。
T68250	Omeprazole magnesium
	Omeprazole magnesium 是口服活性的质子泵（proton pump）抑制剂（PPI），用于抑制胃酸，常用于研究胃酸反流和烧心症相关症状。
T37659	5-hydroxy Omeprazole
	5-hydroxy Omeprazole is a major metabolite of omeprazole , an inhibitor of the gastric H+/K+-ATPase pump.[1] 5-hydroxy Omeprazole is produced from omeprazole by the action of cytochrome P450 (CYP) isoform 2C19, a monooxygenase. [2][3] CYP2C19 polymorphisms significantly influence the metabolism of omeprazole, and individuals may be classified as homozygous extensive metabolizers, heterozygous extensive metabolizers, and poor metabolizers.[1]
T12308	Omeprazole-d3 奥美拉挫 D3,H 16868 D3	Others	Others
	Omeprazole D3 is deuterium labeled Omeprazole. Omeprazole is a proton pump inhibitor (PPI)
T71980	Omeprazole acid
	Omeprazole acid is a medication used in the treatment of gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome. It is also used to prevent upper gastrointestinal bleeding in people who are at high risk. Omeprazole is a proton pump inhibitor and as such blocks the release of stomach acid.
T36840	(R)-Omeprazole (sodium salt)
	(R)-Omeprazole is the inactive isomer of omeprazole , a gastric proton-pump inhibitor. A stereoselective hydroxylation of (R)-omeprazole is mediated primarily by cytochrome P450 (CYP) 2C19, whereas CYP3A4 favors sulfoxidation of the active (S)-enantiomer . (R)-Omeprazole has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 8.1 μM).
T8386	Esomeprazole Magnesium trihydrate 埃索美拉唑镁三水合物,埃索美拉唑镁(三水),(S)-Omeprazole magnesium trihydrate	Proton pump	Membrane transporter/Ion channel
	Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) 是一种口服有效的H+, K+-ATPase 抑制剂，在上消化道疾病和胃食管反流疾病的研究中具有价值。它是一种外泌体抑制剂，通过抑制 V-H+-ATPases 来阻断外泌体的释放。
T66287	(R)-Omeprazole
	(R)-Omeprazole 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66287，CAS号为 119141-89-8。
T20626	Esomeprazole	Proton pump; Cysteine Protease	Membrane transporter/Ion channel; Proteases/Proteasome
	Esomeprazole 是奥美拉唑(omeprazole) 的S-异构体，抑制溶酶体半胱氨酸蛋白酶legumain，防止癌症转移。它是一种质子泵抑制剂（PPI）。
T71259	GNE-900 GNE900,GNE 900	Apoptosis; Chk	Apoptosis; Cell Cycle/Checkpoint
	GNE-900 是一种 ATP 竞争性、选择性和口服活性 ChK1抑制剂，对 ChKl,ChK2的 IC50值分别为为 0.0011，1.5 µM。GNE-900 废除 G2-M 检查点，增强 DNA 损伤，并诱导胞凋亡 (Apoptosis)。gemcitabine 和 GNE-900 给药显示抗肿瘤活性[1]< /sup>。
T68303	Esomeprazole strontium
	Esomeprazole strontium is a gastric proton pump inhibitor.
T61667	Esomeprazole potassium salt
	Esomeprazole potassium salt ((S)-Omeprazole potassium salt) is an effective and orally active proton pump inhibitor that works by inhibiting the H+, K+-ATPase enzyme in the gastric parietal cells, leading to a reduction in acid secretion. It is a promising compound for investigating symptomatic gastroesophageal reflux disease [1] [2] [3].
T61740	Esomeprazole hemistrontium
	Esomeprazole hemistrontium, also known as (S)-Omeprazole, is a potent and orally active proton pump inhibitor that effectively reduces acid secretion by inhibiting the H+, K+-ATPase in gastric parietal cells. This compound exhibits promising potential for research in symptomatic gastroesophageal reflux disease [1] [2] [3].
T61467	Esomeprazole magnesium salt
	Esomeprazole magnesium salt is a potent and orally active proton pump inhibitor that effectively reduces acid secretion in gastric parietal cells by inhibiting the H+, K+-ATPase. This compound has shown promise for the research and treatment of symptomatic gastroesophageal reflux disease [1][2][3].
T23667	AGN-201904 AGN201904,AGN 201904	ATPase	Membrane transporter/Ion channel
	AGN-201904 是质子泵抑制剂，是一种奥美拉唑前药，可延缓衰老，可用于预防和治疗消化性溃疡。
T27669	JNJ-26070109 JNJ26070109
	JNJ-26070109, an antagonist of cholecystokinin CCK2 receptor, inhibits gastric acid secretion and prevents omeprazole-induced acid rebound in the rat.
T26577	AGN-201904Z AGN-201904-Z,AGN-201904
	AGN-201904Z is a slowly absorbed, acid-stable pro-proton pump inhibitor (pro-PPI) rapidly converted to omeprazole in the systemic circulation giving a prolonged residence time. AGN 201904-Z produced a significantly greater, and nocturnal acid suppression

化合物

Cat.No: T0757

Synonym: Losec,Prilosec,奥美拉唑,奥美拉挫,H 16868,Antra

Target: Proton pump, Phospholipase, Antibacterial, Autophagy

Omeprazole metabolite Omeprazole sulfone

Cat.No: T12309

Synonym: Omeprazole sulphone,Omeprazole sulfone

Target: Others

Omeprazole sulfide

Cat.No: T2687

Synonym: Omeprazole metabolite Omeprazole sulfide,Ufiprazole,奥美拉唑硫醚

Target: Proton pump, Drug Metabolite

4-Desmethoxy Omeprazole

Cat.No: T10138

Target: Drug Metabolite

Omeprazole Sodium

Cat.No: T22391

Target: P450, Proton pump, Antibacterial, Autophagy

Esomeprazole Magnesium

Cat.No: T2686

Synonym: (S)-Omeprazole magnesium,NEXIUM,埃索美拉唑镁,(-)-Omeprazole magnesium

Target: ATPase, Proton pump

Esomeprazole Sodium

Cat.No: T2686L

Synonym: 埃索美拉唑钠,(S)-Omeprazole sodium

Target: ATPase, Proton pump

Omeprazole magnesium

Cat.No: T68250

5-hydroxy Omeprazole

Cat.No: T37659

Omeprazole-d3

Cat.No: T12308

Synonym: 奥美拉挫 D3,H 16868 D3

Target: Others

Omeprazole acid

Cat.No: T71980

(R)-Omeprazole (sodium salt)

Cat.No: T36840

Esomeprazole Magnesium trihydrate

Cat.No: T8386

Synonym: 埃索美拉唑镁三水合物,埃索美拉唑镁(三水),(S)-Omeprazole magnesium trihydrate

Target: Proton pump

(R)-Omeprazole

Cat.No: T66287

Cat.No: T20626

Target: Proton pump, Cysteine Protease

Cat.No: T71259

Synonym: GNE900,GNE 900

Target: Apoptosis, Chk

Esomeprazole strontium

Cat.No: T68303

Esomeprazole potassium salt

Cat.No: T61667

Esomeprazole hemistrontium

Cat.No: T61740

Esomeprazole magnesium salt

Cat.No: T61467

Cat.No: T23667

Synonym: AGN201904,AGN 201904

Target: ATPase

Cat.No: T27669

Synonym: JNJ26070109

Cat.No: T26577

Synonym: AGN-201904-Z,AGN-201904

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