首页工具

登录

搜索结果

Search Results for " mp 1 "

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T4212	XMU-MP-1	Hippo pathway	Stem Cells
	XMU-MP-1 是一种促凋亡、无菌的 20 样激酶 MST1 和 2 的抑制剂。
T71901	MP-1
	MP-1 is a covalent inhibitor of fumarate hydratase (FH) that exhibits cytotoxicity dependent on FH. MP-1 engages a functional cysteine in the Zn-finger domain of the tRNA methyltransferase enzyme TRMT1.
T12398	MP7 PDK1 抑制剂,PDK1 inhibitor	PDK	PI3K/Akt/mTOR signaling
	MP7 (PDK1 inhibitor) 是磷酸肌醇依赖性激酶-1 (PDK1) 抑制剂。
T10419	AV-412 MP412	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	AV-412 (MP412) 是一种EGFR 抑制剂，抑制EGFR、EGFRL858R、EGFRT790M、EGFRL858R/T790M 和 ErbB2 的IC50值分别为0.75、0.5、0.79、2.3 和 19 nM。
T69977	BC-1485
	BC-1485 is a first-in-class inhibitor of Fibrosis-inducing E3 ligase 1 (FIEL1 ), which disrupts FIEL1-directed PIAS4 ubiquitination.
T76653	Polybia-MP1
	Polybia-MP1 是一种抗菌素乳苦菌肽。
T80585	Anti-Mouse GM-CSF Antibody (MP1-22E9)	c-Fms	Tyrosine Kinase/Adaptors
	Anti-MouseGM-CSFAntibody 为特异性针对小鼠GM-CSF的IgG2a类免疫球蛋白抗体，由大鼠血清中提取。
T80667	2-Methyl-1-Pyrroline	Others	Others
	2-Methyl-1-Pyrroline (2-MPN）是一种光化学染料的中间体，可诱导 (R）-2-MP的形成。
T6999	Teneligliptin hydrobromide Teneligliptin hydrobromide anhydrous,MP-513 (hydrobromide)	Others; Proteasome; DPP-4	Others; Proteases/Proteasome; Ubiquitination
	Teneligliptin hydrobromide (MP-513(hydrobromide)) 是β2肾上腺素能受体 (β2AR) 阻滞剂，具有抗高血压、抗氧化、清除自由基的活性。
T8445	PU02 PU-02,6-[(1-Naphthalenylmethyl)thio]-9H-purine	Apoptosis; 5-HT Receptor	Apoptosis; GPCR/G Protein; Neuroscience
	PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) 是5-HT3受体的负变构调节剂，是 6-MP 的一个衍生物。它在 HEK293 细胞测得的转染 5-HT3A 和 5-HT3AB 受体后的 IC50值分别为 0.36 和 0.73 μM。
T18365	Mp-polymer ester	Others	Others
	Mp-polymer ester is a noncleavable antibody-drug conjugates (ADCs) linker typically employed in the synthesis of ADCs[1].
T37522	Teneligliptin
	Teneligliptin (MP-513) is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM. Teneligliptin (MP-513) inhibits all these DPP-4 enzymes in a concentration-dependent manner. The IC50s of Teneligliptin (MP-513) for rhDPP-4, human plasma, and rat plasma are 0.889, 1.75, and 1.35 nM, respectively. A study of enzyme inhibition kinetics is conducted for Teneligliptin (M...
T18364	Tesirine MP-PEG8-VA-PABC-PBD Dimer	Others	Others
	MP-PEG8-VA-PABC-PBD Dimer is a drug-linker conjugates for ADC which is used in the treatment of several cancers. PBD Dimer is a DNA alkylating which inhibits DNA replication[1].
T38915	Antibacterial agent 32
	Antibacterial agent 32 exhibits potent antimicrobial activity against E. coli strains NCTC 13351, M 50, and 7 MP, with minimum inhibitory concentration (MIC) values of 1 mcg/mL, 2 mcg/mL, and 8 mcg/mL, respectively (WO2013030733A1, example 43).
T81753	mp-dLAE-PABC-MMAE
	mp-dLAE-PABC-MMAE 是构成抗体药物偶联物 (ADC) 活性部分的化合物。它包括微管蛋白抑制剂 Monomethylauristatin E，并用于ADC的合成。
T36880	NHC-diphosphate
	NHC-diphosphate is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a diphosphate form[1]. NHC is a pyrimidine ribonucleoside and behaves as a potent anti-virus agent. NHC effectively inhibits the replication of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV)[1]. Huh-7 cells are incubated with (10-50 μM; 4 h) NHC or a McGuigan phosphoramidate prodrug of NHC.Intracellular levels of the parental compounds and ...
T36881	NHC-diphosphate triammonium
	NHC-triphosphate triammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a triphosphate form[1]. NHC-triphosphate triammonium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA[1][2]. In an intracellular metabolism assay, HCV replicon cells are treated with 10 μM 3H-labeled NHC, and intracellular nucleotide levels are determined after 1, 2 and 8 hours incubations. NHC is rapidly convered into the mono...

化合物

Cat.No: T4212

Target: Hippo pathway

Cat.No: T71901

Cat.No: T12398

Synonym: PDK1 抑制剂,PDK1 inhibitor

Target: PDK

Cat.No: T10419

Synonym: MP412

Target: EGFR

Cat.No: T69977

Cat.No: T76653

Anti-Mouse GM-CSF Antibody (MP1-22E9)

Cat.No: T80585

Target: c-Fms

2-Methyl-1-Pyrroline

Cat.No: T80667

Target: Others

Teneligliptin hydrobromide

Cat.No: T6999

Synonym: Teneligliptin hydrobromide anhydrous,MP-513 (hydrobromide)

Target: Others, Proteasome, DPP-4

Cat.No: T8445

Synonym: PU-02,6-[(1-Naphthalenylmethyl)thio]-9H-purine

Target: Apoptosis, 5-HT Receptor

Mp-polymer ester

Cat.No: T18365

Target: Others

Cat.No: T37522

Cat.No: T18364

Synonym: MP-PEG8-VA-PABC-PBD Dimer

Target: Others

Antibacterial agent 32

Cat.No: T38915

mp-dLAE-PABC-MMAE

Cat.No: T81753

NHC-diphosphate

Cat.No: T36880

NHC-diphosphate triammonium

Cat.No: T36881

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼