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Cat. No.	Product Name	Target	Signaling Pathways
T78059	Glucagon (Human) Hyperglycemic-glycogenolytic factor,Glukagon	Others	Others
	Glucagon 对蛋白质和氨基酸的代谢产生显著的调节作用。它抑制了氨基酸与肝脏、肌肉以及胰腺蛋白的结合，增加氮的排出，并促进肝脏内尿素的合成。同时，Glucagon 增加了肝脏中转氨酶和尿素循环酶的浓度，提高了肝脏对氨基酸的摄取，并加强了氨基酸与肝糖原之间的结合，从而降低了血液中的氨基酸浓度。
TP1863L	Glucagon (19-29), human acetate	Glucagon Receptor	GPCR/G Protein
	Glucagon (19-29), human acetate 是一种从胰高血糖素加工而来的 COOH 末端片段，是一种有效的胰岛素分泌抑制剂。
T15389L	Glucagon (1-29), bovine, human, porcine hydrochloride 盐酸胰高血糖素,Porcine glucagon hydrochloride,Glucagon hydrochloride	Glucocorticoid Receptor; Glucagon Receptor	Endocrinology/Hormones; GPCR/G Protein
	Glucagon (1-29), bovine, human, porcine hydrochloride 是一种由胰腺 α 细胞产生的多肽激素。它可激活 HNF4α 并促进 HNF4α 磷酸化，促进糖异生。
TP1863	Glucagon (19-29), human
	Glucagon is a 29-amino-acid peptide hormone liberated in the alpha cells of the islets of Langerhans. Glucagon-producing alpha cells represent one of the earliest populations of detectable islet cells in the developing endocrine pancreas.
T15389	Glucagon (1-29), bovine, human, porcine 胰高血糖素,Porcine glucagon,Glucagon	Others	Others
	Glucagon is a peptide hormone, produced by pancreatic α-cells. Glucagon reduces the activity of HNF-4. Glucagon stimulates gluconeogenesis. Glucagon enhances HNF4α phosphorylation.
TP1148L	Glucagon-like peptide 1 (1-37), human acetate	Glucagon Receptor	GPCR/G Protein
	Glucagon-like peptide 1 (1-37), human acetate 是一种高效的 GLP-1 受体激动剂。
TP1487	Glucagon-Like Peptide (GLP) II, human
	Glucagon-like peptide 2 (GLP-2) is a recently identified intestinal epithelium-specific growth factor that has been shown to reduce the severity of inflammatory disorders of the intestine in rodent models. Currently Glucagon-Like Peptide 2 is used as a po
TP1148	Glucagon-like peptide 1 (1-37), human HuGLP-1
	Glucagon-like peptide 1 (1-37), human is a highly potent agonist of the GLP-1 receptor.Pancreatic hormone synthesized by post-translational processing of proglucagon. Unlike truncated forms of GLP-1, it has no effect on food intake in rats and does not en
TP1147	Glucagon-like peptide 1 (1-37), human TFA HuGLP-1 TFA
	Glucagon-like peptide 1 (1-37), human (TFA) is a highly potent agonist of the GLP-1 receptor, it is a kind of pancreatic hormone synthesized by post-translational processing of proglucagon.
TP1157	GLP-2(1-33)(human) GLP-2 (human),Glucagon-like peptide 2 (human)
	GLP-2(1-33) (human) is an enteroendocrine hormone which stimulates the growth of the intestinal epithelium.
T80453	GLP-1 (1-36) amide (human, rat) Glucagon-like Peptide 1 (1-36) amide (human, rat)
	GLP-1(1-36) amide (human, rat)（人类及大鼠的胰高血糖素样肽1（1-36）酰胺）是GLP-1(7-36)酰胺的一种分子变体。该化合物能激发[14C]氨基吡啶在大鼠胃壁细胞的酶分散体中积累。
T3984	GLP-1(7-36), amide MKC 253,胰高血糖素样肽-1,Human GLP-1-(7-36)-amide,Glucagon-like Peptide 1 (7-36) amide,Glucagon-Like Peptide (GLP) I (7-36), amide, human,GLP-1(7-36),GLP-1-(7-36)-amide	Glucagon Receptor	GPCR/G Protein
	GLP-1(7-36), amide (MKC 253) 是一种生理性肠降血糖素，能够刺激胰岛素分泌。
T82309	GLP-1 (1-36) amide (human, rat) (TFA) Glucagon-like Peptide 1 (1-36) amide (human, rat) (TFA)
	GLP-1(1-36) amide (human, rat) TFA为胰高血糖素样肽1(GLP-1)-(7-36)酰胺的分子变体，能够促进[14C]氨基吡啶在大鼠壁细胞的酶分散体中的积累。
T76332	Biotinyl-Glucagon (1-29), human, bovine, porcine
	Biotinyl-Glucagon (1-29), human, bovine, porcine 为带生物素标记的Glucagon衍生物，此肽类激素由胰腺α细胞分泌，功能是提升血液中的葡萄糖与脂肪酸浓度。
T83550	(Asp28)-Glucagon (1-29) (human, rat, porcine)
	'(Asp28)-Glucagon (1-29) (human, rat, porcine)' 为胰高血糖素的一种改良型结构，在第28位氨基酸残基上天冬氨酸（Asp）替换原有残基，显著提高了该化合物在生理pH条件下的溶解性，且保持了与天然胰高血糖素相同的生物活性。
T76628	(Met(O)27)-Glucagon (1-29) (human, rat, porcine)
	'(Met(O)27)-Glucagon (1-29) (human, rat, porcine) 为修饰版胰高血糖素。在大鼠肝细胞内，其促进葡萄糖合成的活性虽与天然胰高血糖素相似，但呈现出较低效率，暗示蛋氨酸对于胰高血糖素与其肝脏受体绑定具有关键性作用。'
T76330	Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide
	Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide 是一种带有生物素标签的Glucagon-like peptide-1-(7-36)，后者为一种具备提升胰岛素释放功能，从而表现出抗糖尿病活性的胃肠道肽。
T76085	Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human
	Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human 是一种被 C 端标记的生物素化 GLP-1(7-36) 酰胺。
T7364	NNC-0640	Glucagon Receptor	GPCR/G Protein
	NNC-0640 是人类胰高血糖素受体阴性变构调节剂(IC50:69.2 nM)。
T22893	L-168049 L-168,049	Glucagon Receptor	GPCR/G Protein
	L-168049 是一种选择性和非竞争性人胰高血糖素受体拮抗剂，对人、鼠和犬的 IC50 分别为 3.7 nM、63 nM 和 60 nM。
T36579	GLP-1R Agonist DMB	Glucagon Receptor	GPCR/G Protein
	GLP-1R Agonist DMB 是胰高血糖素样肽1受体的激动剂（GLP-1R；重组人受体的 KB＝26.3nM）。
T19850	Semaglutide 索玛鲁肽,司美格鲁肽,索马鲁肽	Glucagon Receptor	GPCR/G Protein
	Semaglutide 是人胰高血糖素样肽-1受体激动剂，是一种人胰高血糖素样肽-1 的长效类似物。它有用于 2 型糖尿病研究的潜力。
T3422	GRA Ex-25 GRA-Ex-25	Glucagon Receptor	GPCR/G Protein
	GRA Ex-25 (GRA-Ex-25) 是glucagon 受体抑制剂，其对大鼠和人的 glucagon 受体的IC50值分别为 56 和 55 nM。
T37223	Glucagon Receptor Antagonist I
	Glucagon receptor antagonist I is a competitive antagonist of the glucagon receptor (GCGR; IC50 = 181 nM). It blocks glucagon-induced glycogenolysis in primary human hepatocytes and isolated liver. Glucagon receptor antagonist I, at 50 mg/kg, reduces the increase in glucose levels observed after intraperitoneal administration of glucagon in humanized mice. Glucagon receptor antagonist inactive control does not prevent glucagon-mediated actions.
T36428	PACAP-related Peptide (human) (trifluoroacetate salt)	PACAP	GPCR/G Protein
	PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adenylate cyclase-activating polypeptide . It is expressed in normal human pancreas and adrenal gland tissue and in some tumors that produce vasoactive intestinal peptide (VIP). PRP (1-29) is secreted by CHO-K1 cells that express human recombinant preproPACAP.
T81585	Oxyntomodulin (human, mouse, rat) Proglucagon (33-69)
	Oxyntomodulin (human, mouse, rat) (Proglucagon (33-69)) 是由胰高血糖素前体产生，融合了完整胰高血糖素序列和C端八肽，含37个氨基酸。
T36072	Skyrin Endothianin,Rhodophyscin
	Skyrin is a fungal metabolite characterized by a bisanthraquinone structure. It interferes with glucagon signaling through adenylate cyclase without binding to the glucagon receptor. At 10 μM, skyrin reduces both glucagon-stimulated cAMP production and glycogenolysis. It does not interfere with epinephrine or glucagon-like peptide 1 effects on these parameters.[1] Reference：[1]. Parker, J.C., McPherson, R.K., Andrews, K.M., et al. Effects of skyrin, a receptor-selective glucagon antagonist, in r...
T80565	Gulgafafusp alfa
	Gulgafafusp alfa 为人源化IgG2κ类抗体，专一性靶向GLP1R（胰高血糖素样肽1受体）。
T77791	Dasiglucagon
	Dasiglucagon是一种稳定的人胰高血糖素肽类似物，用于治疗严重低血糖，具有快速且有效的特点。
T72621	GCGR antagonist 2
	GCGR antagonist2 是一种呋喃-2-碳酰肼化合物，是具有口服活性的胰高血糖素受体拮抗剂。GCGR antagonist2 与 hGluR 结合的 Kd 值为 2.3 nM，抑制大鼠受体的 IC50值为 0.43 nM。GCGR antagonist2 可抑制胰高血糖素刺激的糖原分解。
T37577	Glycogen Phosphorylase Inhibitor
	Glycogen phosphorylase in the liver, muscle, and brain initiate glycogenolysis by releasing glucose-1-phosphate from glycogen. Glycogen phosphorylase inhibitor is a cell-permeable acyl urea first identified as an inhibitor of human liver glycogen phosphorylase (IC50 = 53 nM). It blocks glucagon-induced hepatic glycogenolysis in vivo. Glycogen phosphorylase inhibitor has been used to study glycogen utilization in human liver HepG2 cells, retinal explants, and human T lymphocyte Kit 225 cells.
T80149	GRPP (human)
	GRPP (human)为含有30个氨基酸的Gcg衍生肽。该化合物能引起血浆胰岛素的轻微上升及血浆胰高血糖素的轻微降低，但不会影响大鼠胰岛内的胰岛素分泌。
T75822	GLP-1(9-36)amide TFA
	GLP-1(9-36)amide TFA, 作为胰高血糖素样肽-1 (7-36)amide的主要代谢产物，是人胰腺GLP-1受体的拮抗剂。
T36380	GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)
	GLP-1 amide is a peptide hormone cleaved from proglucagon in the pancreas.1,2 Mice lacking the glucagon receptor (Gcgr-/-) have approximately nine-fold higher levels of total GLP-1 amide, including GLP-1 (1-36) amide and truncated GLP-1 (7-36) amide , in pancreatic tissue compared to wild-type mice.2References1. Schjoldager, B.T., Mortensen, P.E., Christiansen, J., et al. GLP-1 (glucagon-like peptide 1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in humans...
T76862	Crotedumab
	Crotedumab (REGN1193) 是一种人源化的 IgG4单克隆抗体，可结合并抑制胰高血糖素受体 (GCGR)，KD 值为 0.1 nM。Crotedumab 可用于糖尿病的研究。
T80084	Retatrutide acetate LY3437943 acetate
	Retatrutide (LY3437943) acetate 是一种针对胰高血糖素受体（GCGR）、葡萄糖依赖性促胰岛素多肽受体（GIPR）和胰高血糖素样肽-1 受体（GLP-1R）的三重肽激动剂。该化合物能有效抑制这三种受体，其EC50值分别为GCGR 5.79 nM、GIPR 0.0643 nM和GLP-1R 0.775 nM，是肥胖研究领域的潜在工具。
T75787	Amylin, amide, human TFA
	Amylin, amide, human TFA 是一种含有37个氨基酸的胰腺多肽，与胰岛素共同分泌，对代谢和维持葡萄糖稳态具有重要作用。该化合物能够抑制胰高血糖素的分泌，延缓胃排空速度，同时作为增加饱腹感的因子。
T76333	(Ser8)-GLP-1 (7-36) amide, human
	(Ser8)-GLP-1 (7-36) amide, human 为源自胰高血糖素原的胰高血糖素样肽-1酰胺，属于 GLP-1(1-36) 酰胺肽裂解产物。作为肠促胰岛素激素，该化合物促进胰腺 β 细胞在葡萄糖依赖性条件下分泌胰岛素，并对消化道的运动与分泌功能产生影响。
T21691	NVP DPP 728 dihydrochloride
	NVP-DPP728 是一种有效、可逆、腈依赖性二肽基肽酶 IV (DPP-IV)抑制剂，Ki 值为 11 nM。NVP-DPP728 可抑制胰高血糖素样肽-1 (GLP-1)的降解，从而增强响应于葡萄糖摄入的胰岛素释放。NVP-DPP728 可用于糖尿病研究。
T73694	Albiglutide TFA
	Albiglutide TFA 是一种胰高血糖素样肽GLP-1模拟物，是长效的GLP-1受体激动剂。Albiglutide TFA 可显著降低糖化血红蛋白 (A1C)。Albiglutide TFA 可用于研究 2 型糖尿病 (T2D)。Albiglutide TFA 是由抗DPP-4的GLP-1二聚体与人白蛋白的基因融合产生的。
TP1302	Somatostatin
	Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin and
T36427	PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)	PACAP	GPCR/G Protein
	Pituitary adenylate cyclase-activating peptide (PACAP) (6-27) is a PACAP receptor antagonist with IC50 values of 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expressed in CHO cells. It binds to PACAP receptors on SH-SY5Y and SK-N-MC human neuroblastoma and T47D human breast cancer cells (IC50s = 24.5, 106, and 105 nM, respectively) and inhibits cAMP accumulation induced by PACAP (1-38) (Kis = 457, 102, and 283 nM, respectively, in SH-SY5Y, ...
T83906	Tirzepatide sodium LY3298176
	Tirzepatide 是一种glucagon-like peptide 1 receptor (GLP-1R) 和 G protein-coupled receptor 119 (GPR119)的激动剂。它在表达人类GLP-1R或GPR119的HEK293细胞中诱导cAMP的产生（EC50s分别为6.54和1.01 nM）。Tirzepatide（100 nM）在表达人类GLP-1R或GPR119的HEK293细胞中诱导受体内化。在体内，Tirzepatide（每天10 nmol/kg）降低高脂饮食诱导的肥胖小鼠模型的体重、食物摄入量、血浆leptin、三酸甘油酯和free fatty acids (FFAs)水平、肝脏三酸甘油酯和血糖水平。它通过每三天给药50 nmol/kg的剂量，阻止A. alternata诱导的A. alternata挑战小鼠的支气管肺泡灌洗液（BALF）中嗜酸性粒细胞和淋巴细胞数量的增加。Tirzepatide（每三天50 nmol/kg）抑制由毒蕈碱受体激动剂methacholine (acetyl-β-methylcholine)导致的在糖尿病诱导的哮喘...

化合物

Glucagon (Human)

Cat.No: T78059

Synonym: Hyperglycemic-glycogenolytic factor,Glukagon

Target: Others

Glucagon (19-29), human acetate

Cat.No: TP1863L

Target: Glucagon Receptor

Glucagon (1-29), bovine, human, porcine hydrochloride

Cat.No: T15389L

Synonym: 盐酸胰高血糖素,Porcine glucagon hydrochloride,Glucagon hydrochloride

Target: Glucocorticoid Receptor, Glucagon Receptor

Glucagon (19-29), human

Cat.No: TP1863

Glucagon (1-29), bovine, human, porcine

Cat.No: T15389

Synonym: 胰高血糖素,Porcine glucagon,Glucagon

Target: Others

Glucagon-like peptide 1 (1-37), human acetate

Cat.No: TP1148L

Target: Glucagon Receptor

Glucagon-Like Peptide (GLP) II, human

Cat.No: TP1487

Glucagon-like peptide 1 (1-37), human

Cat.No: TP1148

Synonym: HuGLP-1

Glucagon-like peptide 1 (1-37), human TFA

Cat.No: TP1147

Synonym: HuGLP-1 TFA

GLP-2(1-33)(human)

Cat.No: TP1157

Synonym: GLP-2 (human),Glucagon-like peptide 2 (human)

GLP-1 (1-36) amide (human, rat)

Cat.No: T80453

Synonym: Glucagon-like Peptide 1 (1-36) amide (human, rat)

GLP-1(7-36), amide

Cat.No: T3984

Synonym: MKC 253,胰高血糖素样肽-1,Human GLP-1-(7-36)-amide,Glucagon-like Peptide 1 (7-36) amide,Glucagon-Like Peptide (GLP) I (7-36), amide, human,GLP-1(7-36),GLP-1-(7-36)-amide

Target: Glucagon Receptor

GLP-1 (1-36) amide (human, rat) (TFA)

Cat.No: T82309

Synonym: Glucagon-like Peptide 1 (1-36) amide (human, rat) (TFA)

Biotinyl-Glucagon (1-29), human, bovine, porcine

Cat.No: T76332

(Asp28)-Glucagon (1-29) (human, rat, porcine)

Cat.No: T83550

(Met(O)27)-Glucagon (1-29) (human, rat, porcine)

Cat.No: T76628

Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide

Cat.No: T76330

Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human

Cat.No: T76085

Cat.No: T7364

Target: Glucagon Receptor

Cat.No: T22893

Synonym: L-168,049

Target: Glucagon Receptor

GLP-1R Agonist DMB

Cat.No: T36579

Target: Glucagon Receptor

Cat.No: T19850

Synonym: 索玛鲁肽,司美格鲁肽,索马鲁肽

Target: Glucagon Receptor

Cat.No: T3422

Synonym: GRA-Ex-25

Target: Glucagon Receptor

Glucagon Receptor Antagonist I

Cat.No: T37223

PACAP-related Peptide (human) (trifluoroacetate salt)

Cat.No: T36428

Target: PACAP

Oxyntomodulin (human, mouse, rat)

Cat.No: T81585

Synonym: Proglucagon (33-69)

Cat.No: T36072

Synonym: Endothianin,Rhodophyscin

Gulgafafusp alfa

Cat.No: T80565

Cat.No: T77791

GCGR antagonist 2

Cat.No: T72621

Glycogen Phosphorylase Inhibitor

Cat.No: T37577

Cat.No: T80149

GLP-1(9-36)amide TFA

Cat.No: T75822

GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)

Cat.No: T36380

Cat.No: T76862

Retatrutide acetate

Cat.No: T80084

Synonym: LY3437943 acetate

Amylin, amide, human TFA

Cat.No: T75787

(Ser8)-GLP-1 (7-36) amide, human

Cat.No: T76333

NVP DPP 728 dihydrochloride

Cat.No: T21691

Albiglutide TFA

Cat.No: T73694

Cat.No: TP1302

PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)

Cat.No: T36427

Target: PACAP

Tirzepatide sodium

Cat.No: T83906

Synonym: LY3298176

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