48
3
14
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP2026L |
GRP (porcine) acetate
GRP (porcine) acetate(74815-57-9 Free base) |
Others | Others |
GRP (porcine) acetate 是从猪胰腺中提取的胃泌素释放肽。 GRP (porcine) acetate 可能在猪胰腺内分泌和外分泌的副交感神经调节中起作用。 | |||
T8701 |
GRP-60367
|
Others | Others |
GRP-60367 是一种小分子狂犬病病毒进入抑制剂,对某些 RABV 株具有纳摩尔作用效果。 | |||
TP2026 |
GRP (porcine)
|
||
Mammalian bombesin-like peptide neurotransmitter that is an agonist for the gastrin-releasing peptide receptor (GRPR). GRP has been reported to activate GABAergic interneurons in the amygdala leading to increased GABA release and fear suppression in mice | |||
T36864 |
GRP (human) (trifluoroacetate salt)
|
||
Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release. It binds to (Ki = 300 nM) and stimulates amylase secretion in rat pancreatic AR42J cells (EC50 = 0.3 nM). GRP increases proliferation of human liver carcinoma HepG2 and MHCC97H cells but does not affect the proliferation of normal HL-7702 liver cells at a concentration of 1 nM. In vivo, GRP (0.35 nmol/kg/h) increases both pancreatic exocrine secretion and pancreatic polypeptide (PP) release in rats. It dose-depend... | |||
T7261 |
Grp94 Inhibitor-1
|
GPR; HSP | Cytoskeletal Signaling; Endocrinology/Hormones; GPCR/G Protein; Metabolism |
Grp94 Inhibitor-1 是一种选择性有效的 Grp94抑制剂,IC50值为 2 nM,是比 Hsp90α 的 1000 倍。 | |||
T82162 |
Human follicular gonadotropin releasing peptide
hF-GRP |
||
Human follicular gonadotropin releasing peptide (hF-GRP)是一种刺激垂体分泌促黄体激素(LH)及促卵泡激素(FSH)的激素类多肽,其作用可在体外实现。 | |||
T61763 |
GRP-60367 hydrochloride
|
||
GRP-60367 hydrochloride is a novel small-molecule entry inhibitor of rabies virus (RABV), exhibiting nanomolar potency against select RABV strains. This first-in-class compound effectively targets the RABV G protein [1]. | |||
T67897 |
GRP78-IN-3
|
HSP | Cytoskeletal Signaling; Metabolism |
GRP78-IN-3(化合物8)是一种有效的Hsp70底物结合的小分子竞争性抑制剂,是一种选择性的Grp78 (HSPA5)抑制剂,IC50为0.59 μM。GRP78-IN-3对HspA5的选择性是HspA9的7倍(IC50为4.3 μM),对HspA5的选择性是HspA2的20倍(IC50为13.9 μM)。 | |||
T80148 |
GRP (14-27) (human, porcine, canine)
|
Bombesin Receptor | GPCR/G Protein |
GRP (14-27) (human, porcine, canine) 表现为铃蟾肽受体配体。其特异性结合受到 GTP 和 GDP 的抑制作用,但 GMP 对此无影响。 | |||
T70088 | Grp94-IN-2 | ||
Grp94-IN-2 is a inhibitor of Grp94. | |||
T63243 |
GRP78-IN-2
|
||
GRP78-IN-2 是葡萄糖调节蛋白 78 (GRP78) 抑制剂,能够优先靶向细胞表面 GRP78,具有显著的的抗血管生成和抗癌作用,且不影响其他正常细胞。 | |||
T61106 | GRP78-IN-1 | ||
GRP78-IN-1 displays interactions with specific residues on the GRP78 protein with a binding energy of -8.07 kcal/mol. This compound possesses potent cytotoxic and anti-proliferative effects on cancer cells, particularly demonstrating promising apoptosis in breast cancer cells and wound healing properties [1]. | |||
T13453 |
CGRP antagonist 1
|
CGRP Receptor | GPCR/G Protein; Neuroscience |
CGRP antagonist 1是高效 CGRP 受体拮抗剂,Ki 值分别为 35nM,IC50 值为 57 nM。CGRP antagonist 1可用于研究心血管疾病和神经血管疾病。 | |||
TP2044L |
α-CGRP (human) acetate
人类降钙素基因相关肽 1,α-CGRP (human) acetate (90954-53-3 free base) |
Others | Others |
α-CGRP (human) acetate 是一种由 37 个氨基酸组成的调节性神经肽。它是一种有效的血管扩张剂,具有正性肌力作用和变时性作用。 | |||
TP1200 |
CGRP (83-119), rat TFA
Calcitonin Gene Related Peptide(83-119), rat TFA |
Others | Others |
CGRP (83-119), rat TFA (Calcitonin Gene Related Peptide(83-119), rat TFA) 是一种由 37 个氨基酸组成的神经肽降钙素家族,通过降钙素受体样受体起作用。 | |||
TP2233L |
CGRP (rat) acetate
|
Others | Others |
CGRP (rat) acetate 是一种降钙素基因相关肽(CGRP)。它是一种有效的血管扩张剂。 | |||
TP1323 |
CGRP 8-37 (rat)
|
CGRP Receptor | GPCR/G Protein; Neuroscience |
CGRP 8-37 (rat) 是 CGRP receptor 拮抗剂,是一种可作用于大鼠的 CGRP片段,具有潜在的抗伤害作用,可诱导动脉松弛。 | |||
TP1134L |
HCGRP-(8-37) acetate
HCGRP-(8-37) acetate (119911-68-1 free base) |
CGRP Receptor | GPCR/G Protein; Neuroscience |
HCGRP-(8-37) acetate 是一种人降钙素基因相关肽 (hCGRP) 片段醋酸盐,也是 CGRP 受体的拮抗剂。 | |||
T63952 | GRPR antagonist-2 | ||
GRPR antagonist-2 是胃泌素释放肽受体 (GRPR) 的有效拮抗剂,对某些癌细胞具有细胞毒性(能够作用于 HGC-27 细胞 (IC50: 0.77 μM) 和 Pan02 细胞 (IC50: 2.5 μM)),表现出抗癌效果。 | |||
T80149 |
GRPP (human)
|
||
GRPP (human)为含有30个氨基酸的Gcg衍生肽。该化合物能引起血浆胰岛素的轻微上升及血浆胰高血糖素的轻微降低,但不会影响大鼠胰岛内的胰岛素分泌。 | |||
T75788 |
α-CGRP(human) TFA
|
||
α-CGRP(human) TFA,一种含37个氨基酸的调节性神经肽,广泛存在于中枢神经系统和周围神经系统中,是一种高效的血管扩张剂。 | |||
TP1203 |
CGRP(83-119), rat
Calcitonin Gene Related Peptide (CGRP) (83-119), rat |
||
Calcitonin Gene Related Peptide (CGRP) (83-119), rat is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor. | |||
TP1131 |
β-CGRP, human TFA (101462-82-2 free base)
CGRP-II (Human) (TFA),Human β-CGRP (TFA),β-CGRP, human TFA |
||
β-CGRP,human tissue is one of the calcitonin peptide, through complex behavior of calcitonin receptor like receptor (CRLR) - and receptor activity - modifying proteins (increased), and 1 and 300 - nM CRLR IC50s/RAMP1 and CRLR/RAMP2 cells. | |||
T76032 |
Calcitonin Gene Related Peptide (CGRP) II, rat TFA
|
||
CalcitoninGene Related Peptide (CGRP) II, rat TFA,为CGRP受体激活剂,具有显著且持久的血管扩张效果,适用于心血管疾病研究。 | |||
TP2215 |
Agouti-related Protein (AGRP) (25-82), human
|
Others | Others |
Agouti-related peptide (AgRP) is a neuropeptide produced in the brain by the AgRP/NPY neuron. It is only synthesized in NPY containing cell bodies located in the ventromedial part of the arcuate nucleus in the hypothalamus. The appetite-stimulating effect | |||
T75732 |
α-CGRP, rat TFA
|
||
α-CGRP, rat TFA 是一种神经肽 (降钙素基因相关肽),主要表达于神经肌肉交界处,是一种有效的血管扩张剂量。α-CGRP, rat TFA 外周给药可使大鼠血压下降、心率升高,并使结肠平滑肌松弛。α-CGRP, rat TFA 可用于心血管、促炎、偏头痛和代谢相关的研究。 | |||
TP2044 |
α-CGRP(human)
α-CGRP (human) |
||
Endogenous calcitonin gene-related peptide receptor (CGRP) agonist. | |||
TP2233 |
α-CGRP, rat
CGRP (rat) |
Others | Others |
Endogenous neuropeptide, potent vasodilator | |||
T36555 |
Tyr-α-CGRP (human) (trifluoroacetate salt)
|
||
Tyr-α-CGRP is an N-terminal extended tyrosinated analogue of α-calcitonin gene-related peptide . It binds to amylin receptors AMY1 and AMY3 in COS-7 cells expressing the human receptors (IC50s = 141 and 1.86 nM, respectively). Tyr-α-CGRP also binds to and stimulates cAMP accumulation in rat L6 myocytes (IC50 = 4 nM; EC50 = 12 nM). It also binds to rat brain and spleen membrane preparations (IC50s = 0.2 and 0.5 nM, respectively), induces positive chronotropic and inotropic effects in isolated rig... | |||
TP1202 |
Calcitonin Gene Related Peptide (CGRP) II, rat
CGRP II, rat |
||
Calcitonin Gene Related Peptide II is a potent, long-lasting vasodilator; activation of CGRP receptors on pancreatic β-cells increases plasma levels of pancreatic enzymes. | |||
T76301 |
Agouti-related Protein (AGRP) (83-132) Amide (human)
|
||
Agouti-related Protein (AGRP) (83-132) Amide (human),一种AGRP的片段,主要在下丘脑弓状核中表达。该化合物主要通过作为黑皮质素-4受体(MC4R)的反向激动剂来增加食物摄入。 | |||
T82079 |
IGRP(206-214)
|
||
IGRP(206-214) 是一种肽,具有生物活性。它对应于非肥胖糖尿病型(NOD)小鼠中胰岛特异性葡萄糖6磷酸酶催化亚基相关蛋白(IGRP)的206-214残基,并能诱导此类小鼠产生糖尿病。此外,该肽对胰岛素原特异性T细胞有着特定的作用。 | |||
T63947 | GRPR antagonist-1 | ||
GRPR antagonist-1 是胃泌素释放肽受体 (GRPR) 的有效拮抗剂,对某些癌细胞具有细胞毒性 (能够作用于 PC3 细胞 (IC50: 4.97 μM)、Pan02 细胞 (IC50: 4.36 μM)、HGC-27 细胞 (IC50: 3.40 μM))。GRPR antagonist-1 能够减少 Bcl-2 水平、提高 Bax 水平,进而抑制 HGC-27 细胞活力,使细胞凋亡,表现出抗癌效果。 | |||
TP1134 |
HCGRP-(8-37)
Human α-CGRP (8-37) |
||
Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist | |||
T78540 |
α-CGRP (mouse, rat) TFA
|
CGRP Receptor | GPCR/G Protein; Neuroscience |
α-CGRP (mouse, rat) TFA 是神经系统中的一种活性神经肽,位于神经肌肉接合部,具有显著的血管舒张功能。适用于心血管疾病、炎症、偏头痛及代谢研究领域。 | |||
TP1201 |
CGRP II, rat (TFA) (99889-63-1 free base)
Calcitonin Gene Related Peptide (CGRP) II, rat (TFA),CGRP II, rat (TFA) |
||
Calcitonin Gene Related Peptide (CGRP) II, rat (TFA) is a neuropeptide with 37 amino acid. | |||
T75978 |
β-CGRP, human TFA
|
||
β-CGRP, human TFA (Human β-CGRP TFA) 是一种降钙素肽,通过降钙素受体样受体CRLR 与RAMP 的复合物起作用,在细胞体系中,对 CRLR/RAMP1 和 CRLR/RAMP2 的IC50值分别为 1 nM 和 300 nM。 | |||
TP1130 |
β-CGRP, human
CGRP-II (Human),Human β-CGRP |
||
β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascular and nervous systems. β-CGRP contains a disulphide bridge at the N-terminus, a C-terminal phenylal | |||
T38190 |
Tyr-α-CGRP (rat) (trifluoroacetate salt)
|
||
Tyr-α-CGRP (rat) is an N-terminally tyrosinated analog of the neuropeptide α-CGRP that induces a fall in resting tension of isolated opossum internal anal sphincter (IAS) with an EC50 value of 178 nM. | |||
TP1325L |
Gastrin-Releasing Peptide, human(TFA)
|
Others | Others |
Gastrin-Releasing Peptide, human(TFA) (93755-85-2 free base) 是一种调节性人类肽,可引发胃泌素释放并调节胃酸分泌和肠道运动功能。支配胃G 细胞的迷走神经节后纤维释放GRP,刺激G 细胞释放胃泌素。 | |||
T35669 |
Neuromedin C (trifluoroacetate salt)
|
||
Neuromedin C is a bombesin-like neuropeptide that stimulates uterine smooth muscle contraction and the release of gastrin , somatostatin, and amylase in rats. Neuromedin C is a truncated form of gastrin-releasing peptide corresponding to the GRP amino acids 18-27. It inhibits GRP and bombesin binding to rat pancreatic membranes (IC50s = 0.4 and 2.2 nM, respectively), which can be reduced by sodium chloride and guanylyl imidodiphosphate . Neuromedin C induces scratching and mast cell degranulatio... | |||
T82881 |
Biotin-Gastrin Releasing Peptide, human
|
||
Biotin-Gastrin Releasing Peptide, human(人源)是一种修饰有生物素的胃泌素释放肽(GRP),此肽具有促进生长和致瘤的神经肽特性。 | |||
TP1325 |
Gastrin-Releasing Peptide, human
|
||
Gastrin-Releasing Peptide, human is a regulatory human peptide that elicits gastrin release and regulates gastric acid secretion and enteric motor function. The post-ganglionic fibers of the vagus nerve that innervate the G cells of the stomach release GRP, which stimulates the G cells to release gastrin. | |||
TP1701 |
RC-3095 TFA
RC-3095 (TFA) |
Bombesin Receptor | GPCR/G Protein |
RC-3095 TFA (RC-3095(TFA)) 是蛙皮素/胃泌素释放肽受体选择性拮抗剂。它能降低关节炎小鼠的胃氧化损伤,从而发挥保护作用。 | |||
T25522 |
Ici 216140
m216140,Ici216140,m 216140,Ici-216140,m-216140 |
||
ICI 216140 is a GRP/bombesin receptor 2 antagonist (IC50: 2 nM in vitro). At 2 mg/kg, it can decrease bombesin-stimulated pancreatic amylase secretion in rats. At 1 mM, it has been proved to attenuate bombesin-stimulated increases in blood pressure in rat | |||
T75834 |
Antagonist G TFA
|
||
Antagonist G TFA 作为后叶加压素(vasopressin)的有效拮抗剂,同时对GRP和缓激肽具有弱拮抗作用。此外,Antagonist G 能够诱导AG-1转录,增强癌细胞对化疗的敏感性。 | |||
T75707 |
BIM-26226
|
||
BIM-26226 是一种胃泌素释放肽,是一种强效选择性的bombesin receptor 拮抗剂。 BIM-26226 抑制 BN 或 GRP 刺激的淀粉酶释放,IC50值在纳摩尔范围内。BIM-26226 可用于癌症研究。 | |||
TP1054 |
PACAP (1-38), human, ovine, rat TFA
Pituitary Adenylate Cyclase Activating Polypeptide 38 (TFA) |
||
PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP), gastrin releasing peptide (GRP), |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP2167 |
β-CGRP, human acetate
β-CGRP, human acetate (101462-82-2 free),CGRP-II (Human) (acetate),Human β-CGRP acetate |
CGRP Receptor | GPCR/G Protein; Neuroscience |
β-CGRP, human acetate 是降钙素肽之一,通过受体活性修饰蛋白 (RAMP) 和降钙素受体样受体 (CRLR) 的复合物发挥作用(对于 CRLR/RAMP1 和 CRLR,IC50:1 nM 和 300 nM /RAMP2 在单元格中)。 | |||
TN1849 |
Kuwanon H
|
GPR; Bombesin Receptor | Endocrinology/Hormones; GPCR/G Protein |
Kuwanon H 是分离自桑白皮的黄酮类化合物,具有拮抗非肽类蛙皮素受体的活性。Kuwanon H 特异性抑制细胞内胃泌激素释放肽 CRP 与GRP-preferring 受体的结合,Ki 为 290 nM。 | |||
T3S1612 |
kuwanon G
桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G |
Phosphatase; Antibacterial; Bombesin Receptor; AChR; AChE; Glucosidase | GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience |
Kuwanon G (Moracenin B) 是一种从桑树中得到的黄酮类蛙皮素受体拮抗剂,具有杀菌作用。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-01370 |
GRP-10 proform Protein, Canine, Recombinant (hFc)
Gastrin-releasing peptide,GRP |
Canine | HEK293 Cells |
Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties, and neuropeptides have previously been suggested to play a role in the complex cascade of chemical activity associated with periodontal inflammation. | |||
TMPY-01577 |
ORP150 Protein, Human, Recombinant (His)
hypoxia up-regulated 1,HSP12A,Grp170,ORP-150,ORP150... |
Human | HEK293 Cells |
Hypoxia up-regulated protein 1, also known as 15 kDa oxygen-regulated protein, 17 kDa glucose-regulated protein, ORP-15, GRP-17, and HYOU1, is a member of the heat shock protein 7 family. Seven members from four different heat shock protein (HSP) families were identified including HYOU1 (ORP15), HSPC1 (HSP86), HSPA5 (Bip), HSPD1 (HSP6), and several isoforms of the two testis-specific HSP7 chaperones HSPA2 and HSPA1L. HYOU1 is highly expressed in tissues that contain well-developed endoplasmic re... | |||
TMPJ-01410 |
LSM4 Protein, Human, Recombinant (His)
Glycine-Rich Protein,GRP,U6 snRNA-Associated Sm-Lik... |
Human | E. coli |
U6 snRNA-associated Sm-like protein LSm4 (LSM4) is a member of the snRNP Sm proteins family. Sm-like proteins contain the Sm sequence motif and are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. LSM4 forms a heteromer with a donut shape. The complexes are involved in various steps of RNA metabolism. LSM4 binds specifically to the 3-terminal U-tract of U6 snRNA. LSM4 contributes RNA protein interactions and structural changes which ar... | |||
TMPJ-01146 |
LGALSL Protein, Human, Recombinant (His)
Lectin Galactoside-Binding-Like Protein,HSPC159,Galectin-Rel... |
Human | E. coli |
Galectin-Related Protein (LGALSL) is a 172 amino acid protein that contains one Galectin domain. LGALSL does not appear to bind carbohydrates or lactose as the critical residues required for binding are not conserved. LGALSL may play a significant role in stimulating smooth muscle growth in developing alveolar wall vessels and the development of pulmonary capillaries. | |||
TMPY-03655 |
GADD45G Protein, Human, Recombinant
GADD45γ,growth arrest and DNA-damage-inducible, γ,DDIT2,grow... |
Human | E. coli |
GADD45G, also known as CR6, is part of the nuclear proteins to interact with various proteins whose transcript levels are raised after stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G reacts to environmental stresses by mediating activation of the p38/JNK pathway which is mediated through their protein binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. GADD45G acts as a new-age tumor suppressor however is being fr... | |||
TMPY-01369 |
AGRP Protein, Human, Recombinant (His)
ASIP2,agouti related neuropeptide,AGRT,ART |
Human | HEK293 Cells |
AGRP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is C6SUN5. | |||
TMPK-00678 |
CALCA/CGRP Protein, Mouse, Recombinant (hFc)
CGRP,Katacalcin,PDN-21,CGRP-I,CGRP |
Mouse | HEK293 Cells |
Specific fragments of methylation changes in the target gene (Calca) were identified by IGV analysis. CGRP was applied to compare the effects on ASCs-T2DM morphology via phalloidin staining, proliferation through CCK-8 assay, and osteogenic differentiation with osteogenic staining, qPCR, and repair of calvarial defect. Furthermore, 5-azacytidine (5-az) was used to intervene ASCs-T2DM to verify the relationship between the methylation level of the target fragment and expression of Calca. | |||
TMPH-00507 |
PGRP-SC2 Protein, Drosophila melanogaster, Recombinant (His & Myc)
|
Fruit fly | E. coli |
N-acetylmuramyl-L-alanine amidase involved in innate immunity by degrading bacterial peptidoglycans (PGN). Probably plays a scavenger role by digesting biologically active PGN into biologically inactive fragments. Has no direct bacteriolytic activity. PGRP-SC2 Protein, Drosophila melanogaster, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 25.2 kDa and the accession number is Q9V4X2. | |||
TMPY-00630 |
AGRP Protein, Rhesus, Recombinant (mFc)
agouti related neuropeptide |
Rhesus | HEK293 Cells |
AGRP Protein, Rhesus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 32.3 kDa and the accession number is A0A8J8XRM3. | |||
TMPY-00661 |
AGRP Protein, Human, Recombinant (hFc)
ART,agouti related neuropeptide,ASIP2,AGRT |
Human | HEK293 Cells |
AGRP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39 kDa and the accession number is C6SUN5. | |||
TMPY-00434 |
AGRP Protein, Mouse, Recombinant (hFc)
Art,agouti related neuropeptide,Agrt |
Mouse | HEK293 Cells |
AGRP Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.1 kDa and the accession number is P56473. | |||
TMPY-02269 |
AGRP Protein, Mouse, Recombinant (His)
Art,agouti related neuropeptide,Agrt |
Mouse | HEK293 Cells |
AGRP Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.7 kDa and the accession number is P56473. | |||
TMPH-00292 |
PGLYRP1/PGRP-S Protein, Bovine, Recombinant (His & Myc)
|
Bovine | E. coli |
PGLYRP1/PGRP-S Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 26.3 kDa and the accession number is Q8SPP7. | |||
TMPJ-01283 |
UGRP1 Protein, Human, Recombinant
Uteroglobin-Related Protein 1,Secretoglobin Family 3A Member... |
Human | E. coli |
Uteroglobin-Related Protein 1 (UGRP1) belongs to the secretoglobin family which has been suggested to play a role in lung inflammation and allergic diseases. UGRP1 is a 17 kDa secreted homodimeric protein that shows amino acid sequence similarity with uteroglobin. UGRP1 is expressed predominantly in the lung and low levels of expression are detected in the thyroid. Expression of UGRP1 in lung epithelial cells is enhanced by IL-10 and decreased through the activities of IL-9 and IL-5. UGRP1 inter... |