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Search Results for " g-csf "

Targets Recommended: Virus Protease HIV Protease CXCR

8

抑制剂 & 化合物

15

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T1776	Plerixafor 普乐沙福,JM3100,AMD 3100,AMD-3329	Virus Protease; HIV Protease; CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Plerixafor (AMD-3329) 是一种趋化因子受体拮抗剂，可阻断基质细胞衍生因子与细胞受体 CXCR4 的结合。它也是 CXCR7 的变构激动剂，是免疫刺激剂和造血干细胞动员剂，还抑制HIV-1和HIV-2的复制，EC50为 1-10 nM。
T4042	Talabostat mesylate Val-boroPro,PT100	Proteasome; DPP-4	Proteases/Proteasome; Ubiquitination
	Talabostat mesylate (PT100) 是一种具有口服活性和非选择性的二肽基肽酶 IV 抑制剂(IC50< 4 nM;Ki= 0.18 nM)。Talabostat mesylate 是成纤维细胞活化蛋白的第一个临床抑制剂(IC50= 560 nM)，抑制 DPP8/9 (IC50= 4/11 nM;Ki= 1.5/0.76 nM)，静息细胞脯氨酸二肽酶(IC50= 310 nM)、DPP2 和一些其他 DASH 家族酶。Talabostat mesylate 具有抗肿瘤和造血刺激活性。
T4650	C188-9 TTI-101	Apoptosis; STAT	Apoptosis; JAK/STAT signaling; Stem Cells
	C188-9 (TTI-101) 是一种Stat3抑制剂，其Kd 值为 4.7 nM。它诱导 AML 细胞系和原代标本凋亡，抑制原代 AML 细胞集落形成。它抑制 G-CSF 诱导的 STAT3 激活和 STAT3 依赖性基因表达。
T82924	Balugrastim CG 10639
	Balugrastim (CG 10639)为新型长效G-CSF，由重组人血清白蛋白与G-CSF遗传融合制成，适用于乳腺癌研究。
T78328	Efbemalenograstim alfa F 627,Bineuta,Benegrastim
	Efbemalenograstim alfa（F 627）为重组长效二聚体G-CSF，融合了两个人源G-CSF与人免疫球蛋白G2（hIgG2）-Fc片段，并能有效促进白细胞生成。
T77172	Eflapegrastim
	Eflapegrastim 是一种人源化IgG4单抗，也是一种粒细胞集落刺激因子 (G-CSF)。Eflapegrastim 靶向G-CSF 受体 (c-Fms)。Eflapegrastim 刺激中性粒细胞祖细胞的增殖和分化，维持成熟和功能性中性粒细胞数目稳定。Eflapegrastim 还缩短中性粒细胞减少的持续时间。
T76908	Anumigilimab
	Anumigilimab (CSL-324) 是一种人源化IgG2a 单抗，靶向人粒细胞集落刺激因子 (G-CSF) 受体。Anumigilimab 可用于炎症部位中性粒细胞数量增加的研究。
T33267	Me6TREN 4HCl Me6TREN Tetrahydrochloride,Me6-TREN Tetrahydrochloride,Me6 4HCl,Me 6 4HCl,Me-6 4HCl
	Me6TREN 4HCl is a potent and efficacious mobilizing agent of hematopoietic stem and progenitor cells (HSPCs) that can act by activating MMP-9 expression and disrupting the SDF-1α/CXCR4 axis, exhibiting more significant mobilizing effects than G-CSF or AMD

化合物

Cat.No: T1776

Synonym: 普乐沙福,JM3100,AMD 3100,AMD-3329

Target: Virus Protease, HIV Protease, CXCR

Talabostat mesylate

Cat.No: T4042

Synonym: Val-boroPro,PT100

Target: Proteasome, DPP-4

Cat.No: T4650

Synonym: TTI-101

Target: Apoptosis, STAT

Cat.No: T82924

Synonym: CG 10639

Efbemalenograstim alfa

Cat.No: T78328

Synonym: F 627,Bineuta,Benegrastim

Cat.No: T77172

Cat.No: T76908

Cat.No: T33267

Synonym: Me6TREN Tetrahydrochloride,Me6-TREN Tetrahydrochloride,Me6 4HCl,Me 6 4HCl,Me-6 4HCl

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05636	G-CSF Protein, Mouse, Recombinant G-CSF,MGI-IG,Csf	Mouse	HEK293 Cells
	G-CSF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19 kDa and the accession number is P09920.
TMPY-04829	G-CSF Protein, Human, Recombinant G-CSF,colony stimulating factor 3...	Human	HEK293 Cells
	G-CSF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.7 kDa and the accession number is P09919-2.
TMPJ-00091	G-CSF Protein, Mouse, Recombinant (His) Csf3,G-CSF,Granulocyte c...	Mouse	HEK293 Cells
	Granulocyte colony-stimulating factor (G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. G-CSF binding to its receptor G-CSF-R which belongs to the cytokine receptor type I family depends on the interaction of ...
TMPY-02312	CSF3R/G-CSFR Protein, Human, Recombinant (His) CSF3R,GCSFR,colony stimulatin...	Human	HEK293 Cells
	CSF3R/G-CSFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 68 kDa and the accession number is Q99062-1.
TMPY-00813	G-CSF Protein, Human, Recombinant (hFc) CSF3OS,C17orf33,colony stimulating factor ...	Human	HEK293 Cells
	G-CSF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.4 kDa and the accession number is P09919-2.
TMPK-00876	G-CSFR/CD114 Protein, Mouse, Recombinant (His) CD114,G CSF R,G-CSF-R,	Mouse	HEK293 Cells
	The Granulocyte Colony-Stimulating Factor (G-CSF) receptor, a member of the hematopoietin cytokine receptor superfamily, functions as a homodimer and requires the recruitment of cytosolic protein tyrosine kinases (PTKs) to transduce its signal.
TMPY-00814	CSF3R/G-CSFR Protein, Human, Recombinant (hFc) G-CSF R,GCSFR,CD114,...	Human	HEK293 Cells
	CSF3R/G-CSFR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 93.3 kDa and the accession number is Q99062-1.
TMPH-00490	G-CSF Protein, Canine, Recombinant (His & SUMO) GCSF	Canine	E. coli
	G-CSF Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli.
TMPJ-01467	Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His) Oncostatin-M,OSM	Human	E. coli
	Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, which Inhibits the proliferation of a number of tumor cell lines. It stimulates proliferation of AIDS-KS cells. OSM regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is considered as a pleiotropic cytokine that initiates its biological ac...
TMPJ-00895	SCF Protein, Rat, Recombinant (HEK293, His) steel factor,Mast cell growth factor,SLF,MG	Rat	HEK293 Cells
	SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. In phase I/II...
TMPH-03345	Oncostatin M/OSM Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	Growth regulator. Inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses only type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration. Oncostatin M/OSM Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis tag. The predicted molecular weight is 24.2 kDa and ...
TMPY-02577	NAMPT Protein, Human, Recombinant (His & GST) VISFATIN,PBEF,PBEF1,1110035O14Rik,VF,nicotinamide phosphorib...	Human	Baculovirus Insect Cells
	Nicotinamide phosphoribosyltransferase (NAMPT), also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin, is an enzyme belonging to the family of glycosyltransferases, to be specific, the pentosyltransferases. This enzyme participates in nicotinate and nicotinamide metabolism. This enzyme catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1- pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. NAMPT is...
TMPY-01416	OLFM4 Protein, Human, Recombinant (His) hGC-1,GC1,OLM4,bA209J19.1,GW112,o...	Human	HEK293 Cells
	Olfactomedin-4, also known as G-CSF-stimulated clone 1 protein, Antiapoptotic protein GW112, and OLFM4, is a secreted protein that contains one olfactomedin-like domain. The OLFM4 gene was recently reported to inhibit various apoptotic pathways and promote the proliferation of cancer cells, suggesting that OLFM4 might serve as a diagnostic marker for human cancers. Thus, OLFM4 mRNA might be a useful tool to support the diagnosis of cancer, irrespective of the clinical stages. It is overexpressed...
TMPK-01411	Peptide Ready HLA-G&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated Peptide Ready,HLA-G,MHC	Human	HEK293 Cells
	Peptide Ready HLA-G&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-G. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01418	Peptide Ready HLA-G&B2M Monomer Protein, Human, MHC (His & Avi) MHC,HLA-G,Peptide Ready	Human	HEK293 Cells
	Peptide Ready HLA-G&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-G. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.

重组蛋白

G-CSF Protein, Mouse, Recombinant

Cat.No: TMPY-05636

Species: Mouse

Expression System: HEK293 Cells

G-CSF Protein, Human, Recombinant

Cat.No: TMPY-04829

Species: Human

Expression System: HEK293 Cells

G-CSF Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00091

Species: Mouse

Expression System: HEK293 Cells

CSF3R/G-CSFR Protein, Human, Recombinant (His)

Cat.No: TMPY-02312

Species: Human

Expression System: HEK293 Cells

G-CSF Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00813

Species: Human

Expression System: HEK293 Cells

G-CSFR/CD114 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00876

Species: Mouse

Expression System: HEK293 Cells

CSF3R/G-CSFR Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00814

Species: Human

Expression System: HEK293 Cells

G-CSF Protein, Canine, Recombinant (His & SUMO)

Cat.No: TMPH-00490

Species: Canine

Expression System: E. coli

Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPJ-01467

Species: Human

Expression System: E. coli

SCF Protein, Rat, Recombinant (HEK293, His)

Cat.No: TMPJ-00895

Species: Rat

Expression System: HEK293 Cells

Oncostatin M/OSM Protein, Rat, Recombinant (His)

Cat.No: TMPH-03345

Species: Rat

Expression System: HEK293 Cells

NAMPT Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02577

Species: Human

Expression System: Baculovirus Insect Cells

OLFM4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01416

Species: Human

Expression System: HEK293 Cells

Peptide Ready HLA-G&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01411

Species: Human

Expression System: HEK293 Cells

Peptide Ready HLA-G&B2M Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01418

Species: Human

Expression System: HEK293 Cells

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