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Search Results for " carbonic acid "

13

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T60015	TSPO ligand-2 Carbonic acid	AUTACs	PROTAC
	TSPO ligand-2 (Carbonic acid) 是 AUTAC1 的配体，AUTAC1含有一个对氟苄基鸟嘌呤和一个烟曲霉醇部分。
T22426	Sodium carbonate 碳酸钠,Soda Ash,Disodium carbonate,Carbonic acid disodium salt	Others	Others
	Sodium carbonate (Soda Ash) 又称碳酸二钠、纯碱、碳酸二钠盐，是具有碱化性能的碳酸二钠盐。
T30744	Carbonic acid, (3-iodophenyl)methyl octyl ester
	Carbonic acid, (3-iodophenyl)methyl octyl ester is a bioactive chemical.
T31674	Erythromycin ethyl carbonate Erythromycin 2''-carbonic acid ethyl ester
	Erythromycin ethyl carbonate is a bioactive chemical.
T0675	Topiramate RWJ 17021,McN 4853,托吡酯	Potassium Channel; Calcium Channel; GABA Receptor; Sodium Channel; GluR; Carbonic Anhydrase; iGluR	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Topiramate (RWJ 17021) 是一种GluR5受体拮抗剂，可通过增强GABAergic 活性，抑制kainate/AMPA 受体，抑制钠和钙通道的电压敏感，增加钾电导并抑制碳酸酐酶来产生抗癫痫作用，用于治疗部分性和全身性癫痫发作。
T2134	Dorzolamide hydrochloride MK507 hydrochloride,L671152 hydrochloride,MK-507 (L-671152) HCl,盐酸多佐胺,Dorzolamide HCl	Carbonic Anhydrase	Metabolism
	Dorzolamide hydrochloride (MK507 hydrochloride) 是一种碳酸酐酶carbonic anhydrase II 抑制剂，能够抑制红细胞CA-II(IC50:0.18 nM) 和CA-I(IC50:600 nM) 。
T38808	Cyclamic acid sodium Cyclohexylsulfamicacidsodium,Sodiumcyclamate	Carbonic Anhydrase	Metabolism
	Cyclamic acid sodium (Cyclohexylsulfamicacidsodium) 是一种碳酸酐酶抑制剂，是食品和药品中使用最广泛的人工甜味剂之一。Cyclamic acid sodium 在最大电休克惊厥发作模型显示出中等的抗惊厥活性。Cyclamic acid sodium 可用于研究癌症。
T0291	Flurbiprofen 氟比洛芬,dl-Flurbiprofen	Apoptosis; COX; MRP	Apoptosis; Immunology/Inflammation; Neuroscience
	Flurbiprofen (dl-Flurbiprofen) 是一种高效的，具有口服活性的非甾体抗炎化合物，有退热止痛活性, 常用于炎症性疾病的研究。它是一种非选择性的环氧合酶抑制剂，可研究结肠癌。
T0782	Benzthiazide Aquatag,苄噻嗪,Lemazide,Dihydrex	Carbonic Anhydrase	Metabolism
	Benzthiazide (Lemazide) 是长效利尿剂及抗高血压剂。它也是碳酸酐酶 9 的抑制剂，他对 CA9，CA2 和 CA1 的 Ki 分别为 8.0，8.8 和 10 nM。它对肿瘤细胞增殖具有抑制作用。
T69082	Flurbiprofen sodium
	Flurbiprofen sodium is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting carbonic anhydrase.
T63158	hCAIX-IN-10
	hCAIX-IN-10 (Compound 6i) 是一种选择性碳酸酐酶 IX 和 XII 抑制剂，作用于 hCA IX (Ki: 61.5 nM) 和 hCA XII (Ki: 586.8 nM)。其中 hCA IX 和 hCA XII 是一种跨膜同工型碳酸酐酶，能够作为一些类型肿瘤的生物标志物。hCA XII 有助于正常细胞和肿瘤细胞中酸碱平衡的维持。
TMIH-0523	Sodium cyclamate-d4
	Sodium cyclamate-d4 是 Sodium cyclamate 的氘代化合物。Sodium cyclamate 的 CAS 号为 139-05-9。Cyclamic acid sodium是一种碳酸酐酶抑制剂，是食品和药品中使用最广泛的人工甜味剂之一。Cyclamic acid sodium在最大电休克惊厥发作模型显示出中等的抗惊厥活性。Cyclamic acid sodium可用于研究癌症。
T37847	Zonisamide-13C2,15N Zonisamide-13C2,15N
	Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium...

化合物

Cat.No: T60015

Synonym: Carbonic acid

Target: AUTACs

Sodium carbonate

Cat.No: T22426

Synonym: 碳酸钠,Soda Ash,Disodium carbonate,Carbonic acid disodium salt

Target: Others

Carbonic acid, (3-iodophenyl)methyl octyl ester

Cat.No: T30744

Erythromycin ethyl carbonate

Cat.No: T31674

Synonym: Erythromycin 2''-carbonic acid ethyl ester

Cat.No: T0675

Synonym: RWJ 17021,McN 4853,托吡酯

Target: Potassium Channel, Calcium Channel, GABA Receptor, Sodium Channel, GluR, Carbonic Anhydrase, iGluR

Dorzolamide hydrochloride

Cat.No: T2134

Synonym: MK507 hydrochloride,L671152 hydrochloride,MK-507 (L-671152) HCl,盐酸多佐胺,Dorzolamide HCl

Target: Carbonic Anhydrase

Cyclamic acid sodium

Cat.No: T38808

Synonym: Cyclohexylsulfamicacidsodium,Sodiumcyclamate

Target: Carbonic Anhydrase

Cat.No: T0291

Synonym: 氟比洛芬,dl-Flurbiprofen

Target: Apoptosis, COX, MRP

Cat.No: T0782

Synonym: Aquatag,苄噻嗪,Lemazide,Dihydrex

Target: Carbonic Anhydrase

Flurbiprofen sodium

Cat.No: T69082

Cat.No: T63158

Sodium cyclamate-d4

Cat.No: TMIH-0523

Zonisamide-13C2,15N

Cat.No: T37847

Synonym: Zonisamide-13C2,15N

Cat. No.	Product Name	Target	Signaling Pathways
TN3058	4-O-Methylgrifolic acid	Others	Others
	4-O-Methylgrifolic acid is a natural carbonic anhydrase Ⅱ(CAⅡ) inhibitor, it shows in-hibitory activities against CAⅡ with IC50s in the range of 6.37-71.73 umol/L.
TN4167	Grifolic acid	Antifection	Microbiology/Virology
	Grifolic acid is a natural carbonic anhydrase Ⅱ inhibitor(CAⅡ), it shows in-hibitory activities against CAⅡ with IC50 of 6.37 umol/L. Grifolic acid has antibacterial activity, it can inhibit the growth of Staphylococcus aureus and Staphylococcus epidermid

天然产物

4-O-Methylgrifolic acid

Cat.No: TN3058

Target: Others

Grifolic acid

Cat.No: TN4167

Target: Antifection

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