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Targets Recommended: Reverse Transcriptase Dopamine Receptor Autophagy

11

抑制剂 & 化合物

1

化合物库

1

TargetMol 试剂盒

10

重组蛋白

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Cat. No.	Product Name
L1380	转录因子库		695 compounds
	695 种转录因子靶向、结构新颖的化合物；

化合物库

转录因子库

Cat.No: L1380

Compounds: 695

Cat. No.	Product Name	Form	Specificity Of Inhibition
CL0077	Reverse Transcriptase inhibitor kit Reverse Transcriptase inhibitor kit

TargetMol 试剂盒

Reverse Transcriptase inhibitor kit

Cat.No: CL0077

Cat. No.	Product Name	Target	Signaling Pathways
T5842	Bromocriptine mesylate 甲磺酸溴隐亭,CB-154	Dopamine Receptor; Autophagy	Autophagy; GPCR/G Protein; Neuroscience
	Bromocriptine mesylate (CB-154) 是一种有效的多巴胺受体激动剂，以最高的亲和力结合 D2 受体，Ki 为 2.5 nM。
T6980	Scriptaid GCK1026,Scriptide	Apoptosis; Influenza Virus; HDAC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology
	Scriptaid (GCK1026) 是一种组蛋白去乙酰化酶抑制剂，也是抗病毒药的敏化剂。它可研究癌症，与爱泼斯坦-巴尔病毒相关的淋巴瘤。
T12715	Reverse transcriptase-IN-1	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Reverse transcriptase-IN-1 是一种二芳基苯并嘧啶类似物，是一种有效的 HIV-1 非核苷类逆转录酶抑制剂，IC50 为 13.7 nM。
T12218	NFAT Transcription Factor Regulator-1	IL Receptor	Immunology/Inflammation
	NFAT Transcription Factor Regulator-1 是 IL-2 合成的抑制剂，IC50 值为182 nM。
T72658	cRIPGBM chloride
	cRIPGBM chloride是一种口服有效的促凋亡衍生物，针对多形性胶质母细胞瘤(GBM)中的癌症干细胞(CSC)。该化合物通过靶向受体相互作用蛋白激酶2(RIPK2)，诱导caspase 1依赖的细胞凋亡，抑制RIPK2/TAK1的活性，增加RIPK2/caspase 1复合物的形成，表现出强大的体内抗肿瘤效果。
T68440	Epicriptine
	Epicriptine or beta-dihydroergocryptine is a dopamine agonist of the ergoline class. It constitutes one third of the mixture known as dihydroergocryptine, the other two thirds consisting of alpha-dihydroergocryptine. The alpha differs from the beta form only in the position of a single methyl group, which is a consequence of the biosynthesis in which the proteinogenic amino acid isoleucine is replaced by leucine.
T72206	Reverse transcriptase-IN-4
	Reverse transcriptase-IN-4 是一种有效的选择性非核苷类逆转录酶 (NNRT) 抑制剂，作用于野生型HIV-1的EC50值为 0.053 μM，作用于HIV-1突变株 E138K 的EC50值为 0.26 μM。
T40459	Transcriptional Intermediary Factor 2 (TIF2) (740-753) Transcriptional Intermediary Factor 2 (TIF2) (740-753)
	Transcriptional Intermediary Factor 2 (TIF2) (740-753) is a 14-amino acid peptide that serves as a coactivator of TIF-2 protein. It specifically covers residues 740-753 of the TIF-2 protein.
T72203	Reverse transcriptase-IN-3
	Reverse transcriptase-IN-3, 作为一种嘧啶-5-羧酰胺衍生物，主要用于抑制HIV-1。它对HIV-1野生型及其突变型病毒株均展示出高效的抑制活性。
TP2291	signal transducer and activator of transcription 6 fragment	Others	Others
	The signal transducer and activator of transcription 6 fragments is a peptide with the sequence H2N-Ser-Tyr-Trp-Ser-Asp-Arg-Leu-Ile-Ile-OH, MW= 1152.3.
T19250	cRIPGBM	TNF	Apoptosis
	cRIPGBM 是RIPGBM 的促凋亡衍生物。cRIPGBM 通过与受体相互作用蛋白激酶2(RIPK2)结合，从而选择性诱导 GBM 肿瘤干细胞凋亡，对 GBM-1 细胞的EC50值为 68 nM。

化合物

Bromocriptine mesylate

Cat.No: T5842

Synonym: 甲磺酸溴隐亭,CB-154

Target: Dopamine Receptor, Autophagy

Cat.No: T6980

Synonym: GCK1026,Scriptide

Target: Apoptosis, Influenza Virus, HDAC, Autophagy

Reverse transcriptase-IN-1

Cat.No: T12715

Target: HIV Protease

NFAT Transcription Factor Regulator-1

Cat.No: T12218

Target: IL Receptor

cRIPGBM chloride

Cat.No: T72658

Cat.No: T68440

Reverse transcriptase-IN-4

Cat.No: T72206

Transcriptional Intermediary Factor 2 (TIF2) (740-753)

Cat.No: T40459

Synonym: Transcriptional Intermediary Factor 2 (TIF2) (740-753)

Reverse transcriptase-IN-3

Cat.No: T72203

signal transducer and activator of transcription 6 fragment

Cat.No: TP2291

Target: Others

Cat.No: T19250

Target: TNF

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03459	CRIP2 Protein, Human, Recombinant CRP2,cysteine-rich protein 2,ESP1,CRIP	Human	Baculovirus Insect Cells
	CRIP2 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 22.6 kDa and the accession number is P52943.
TMPY-03342	CRIP2 Protein, Human, Recombinant (His & GST) CRIP,ESP1,CRP2,cysteine-rich protein 2	Human	Baculovirus Insect Cells
	CRIP2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 50.3 kDa and the accession number is P52943.
TMPY-01413	Cripto Protein, Human, Recombinant (His) CR,CRIPTO,teratocarcinoma-derived growth factor 1,C...	Human	HEK293 Cells
	Cripto Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is AAH22393.1.
TMPY-05503	Cripto Protein, Human, Recombinant (hFc) teratocarcinoma-derived growth factor 1,CR,CRIPTO,C...	Human	HEK293 Cells
	Cripto Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number is P13385.
TMPY-02679	Cripto Protein, Rat, Recombinant (hFc) teratocarcinoma-derived growth factor 1	Rat	HEK293 Cells
	Cripto Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is XP_001056317.2.
TMPH-01799	Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO)	Human	E. coli
	Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 95.2 kDa and the accession number is P17480.
TMPY-03750	CRIPT Protein, Human, Recombinant (His) HSPC139,SSMDF,cysteine-rich PDZ-binding protein	Human	E. coli
	CRIPT, also known as cysteine-rich PDZ-binding protein, belongs to the CRIPT family. It interacts with TUBB1. CRIPT also interacts strongly with the PDZ3 domain of members of the DLG4 family. It is involved in the cytoskeletal anchoring of DLG4 in excitatory synapses. CRIPT is highly conserved from mammals to plants and binds selectively to the third PDZ domain (PDZ3) of PSD-95 via its C terminus. n heterologous cells, CRIPT causes a redistribution of PSD-95 to microtubules. In brain, CRIPT colo...
TMPH-01798	Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO)	Human	E. coli
	Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO tag. The predicted molecular weight is 107.9 kDa and the accession number is P17480.
TMPY-03908	Cripto Protein, Rat, Recombinant (His) teratocarcinoma-derived growth factor 1	Rat	HEK293 Cells
	Cripto Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.5 kDa and the accession number is XP_001056317.2.
TMPK-00073	TDGF1/Cripto Protein, Human, Recombinant (His) TDGF1,Cripto,CR,CRGF	Human	HEK293 Cells
	TDGF1 (CRIPTO) is a member of the epidermal growth factor-Cripto-1/FRL-1/Cryptic (EGF/CFC) gene family and an obligate co-receptor involved in NODAL signaling, a developmental program implicated in midline, forebrain, and left-right axis development in model organisms. Cripto-1 is enriched in a subpopulation of embryonal, melanoma, prostate, and pancreatic cancer cells that possess stem-like characteristics. Therefore, Cripto-1 may play a role during developmental EMT, and it may also be involve...

重组蛋白

CRIP2 Protein, Human, Recombinant

Cat.No: TMPY-03459

Species: Human

Expression System: Baculovirus Insect Cells

CRIP2 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-03342

Species: Human

Expression System: Baculovirus Insect Cells

Cripto Protein, Human, Recombinant (His)

Cat.No: TMPY-01413

Species: Human

Expression System: HEK293 Cells

Cripto Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05503

Species: Human

Expression System: HEK293 Cells

Cripto Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-02679

Species: Rat

Expression System: HEK293 Cells

Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO)

Cat.No: TMPH-01799

Species: Human

Expression System: E. coli

CRIPT Protein, Human, Recombinant (His)

Cat.No: TMPY-03750

Species: Human

Expression System: E. coli

Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO)

Cat.No: TMPH-01798

Species: Human

Expression System: E. coli

Cripto Protein, Rat, Recombinant (His)

Cat.No: TMPY-03908

Species: Rat

Expression System: HEK293 Cells

TDGF1/Cripto Protein, Human, Recombinant (His)

Cat.No: TMPK-00073

Species: Human

Expression System: HEK293 Cells

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