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Search Results for " cdd "

Targets Recommended: Epigenetic Reader Domain

15

抑制剂 & 化合物

9

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T72058L	CDD-1102 HCl CDD-1102 HCl(2757619-84-2 Free base)	Epigenetic Reader Domain	Chromatin/Epigenetic
	CDD-1102 HCl 是一种新型BRDT-BD4 / BRD2-BD1302选择性抑制剂，在体内外实验中显示出非激素避孕潜力。
T13600	CDD3505 4-nitro-1-trityl-1H-imidazole	P450	Metabolism
	CDD3505 (4-nitro-1-trityl-1H-imidazole) 能够诱导肝CYP3A 的活动，增强高密度脂蛋白胆固醇的水平。
T13601	CDD3506 1-TRITYL-1H-IMIDAZOL-4-AMINE	P450	Metabolism
	CDD3506 (1-TRITYL-1H-IMIDAZOL-4-AMINE) 能够诱导肝CYP3A 的活动，增强高密度脂蛋白胆固醇的水平。
T79344	CDD-1819	SARS-CoV	Microbiology/Virology
	CDD-1819为非共价、非肽类SARS-CoV-2 Mpro有效抑制剂，其Ki值为5 nM。该化合物同样抑制ΔP168、A173V及ΔP168/A173V Mpro突变体。
T79345	CDD-1733	SARS-CoV	Microbiology/Virology
	CDD-1733是SARS-CoV-2 Mpro的非共价非肽抑制剂，具有12 nM的Ki值。该化合物也能够抑制ΔP168、A173V及ΔP168/A173V Mpro突变体。
T39126	Zunsemetinib CDD-450,ATI-450
	Zunsemetinib (CDD-450) is a potent and specific inhibitor of the p38α-MK2 pathway, exerting its effects through oral administration. It has proven activity against immuno-inflammatory diseases, making it a valuable tool for research in this area.
T79346	CDD-1845	SARS-CoV	Microbiology/Virology
	CDD-1845，一种非共价非肽类SARS-CoV-2 Mpro抑制剂，具有3 nM的Ki值。该化合物同样能抑制ΔP168、A173V及ΔP168/A173V的Mpro突变体。
TP2357	Ularitide CDD 95-126,ANP 95-126,Human urodilatin
	Ularitide is a 32-amino acid peptide derived from (95-126 residues) of ANP PROHORMONE (1-126 residues). It isn't biologically inactivated by a peptidase from dog kidney cortex membranes.
T80662	CDD0102 HCl CDD0102A HCl	AChR	Neuroscience
	CDD0102 HCl 是一种具有选择性和有效的 M1 毒蕈碱 (Muscarinic) 受体激动剂，可用于治疗阿尔兹海默症。
T10731	CDD0102 CDD0102A	AChR	Neuroscience
	CDD0102 is a potent agonist of M1 Muscarinic receptor.
T10733	CDDO-EA TP319,CDDO ethyl amide,RTA 405	Nrf2	Immunology/Inflammation
	CDDO-EA (CDDO ethyl amide) 是 Nrf2/抗氧化反应元件的激活剂。
T13603	CDDO-3P-Im	Necroptosis	Apoptosis
	CDDO-3P-Im 是一种具有口服活性的坏死性凋亡抑制剂，具有化学预防作用。 CDDO-3P-Im 可用于有关缺血/再灌注的研究。
T13604	CDDO-dhTFEA	Others; NF-κB; Nrf2	Immunology/Inflammation; NF-κB; Others
	CDDO-dhTFEA 是合成的齐墩果烷三萜化合物，可有效激活Nrf2并抑制促炎转录因子NF-κB。它可以恢复高血压 (MAP)，提高 Nrf2 及其靶基因的表达，抑制 NF-κB 的活化和转化生长因子-β 途径，并减少慢性肾病 (CKD) 大鼠的肾小球硬化，间质纤维化和炎症。
T13602	CDDO-2P-Im CDDO-2-P-Im	Others	Others
	CDDO-2P-Im 在小鼠肺癌模型中显示出化学预防作用并降低了肺肿瘤的大小和严重程度。
TQ0120	CDDO-Im RTA-403,CDDO-Imidazolide,TP-235	Others; Ferroptosis; Nrf2; PPAR	Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Others
	CDDO-Im (TP-235) 是一种 Nrf2和 PPAR 的激活剂，对 PPARα 和 PPARγ 的 Ki 分别为232 nM 和 344 nM。

化合物

Cat.No: T72058L

Synonym: CDD-1102 HCl(2757619-84-2 Free base)

Target: Epigenetic Reader Domain

Cat.No: T13600

Synonym: 4-nitro-1-trityl-1H-imidazole

Target: P450

Cat.No: T13601

Synonym: 1-TRITYL-1H-IMIDAZOL-4-AMINE

Target: P450

Cat.No: T79344

Target: SARS-CoV

Cat.No: T79345

Target: SARS-CoV

Cat.No: T39126

Synonym: CDD-450,ATI-450

Cat.No: T79346

Target: SARS-CoV

Cat.No: TP2357

Synonym: CDD 95-126,ANP 95-126,Human urodilatin

Cat.No: T80662

Synonym: CDD0102A HCl

Target: AChR

Cat.No: T10731

Synonym: CDD0102A

Target: AChR

Cat.No: T10733

Synonym: TP319,CDDO ethyl amide,RTA 405

Target: Nrf2

Cat.No: T13603

Target: Necroptosis

Cat.No: T13604

Target: Others, NF-κB, Nrf2

Cat.No: T13602

Synonym: CDDO-2-P-Im

Target: Others

Cat.No: TQ0120

Synonym: RTA-403,CDDO-Imidazolide,TP-235

Target: Others, Ferroptosis, Nrf2, PPAR

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00925	SOST Protein, Human, Recombinant (His) VBCH,sclerostin,DAND6,CDD,SOST1	Human	HEK293 Cells
	SOST Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is Q9BQB4-1.
TMPY-05113	SOST Protein, Human, Recombinant (His), Biotinylated VBCH,SOST1,DAND6,sclerostin,CDD	Human	HEK293 Cells
	SOST Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is Q9BQB4-1.
TMPK-01293	SOST Protein, Cynomolgus, Recombinant (His) VBCH,SOST1,sclerostin,DAND6,SOST,CDD,VBCHsclerosteo...	Cynomolgus	HEK293 Cells
	SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. SOST Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 22.58 kDa and the accession number is XP_005584428.2.
TMPK-00103	SOST Protein, Human, Recombinant (His & Avi), Biotinylated VBCH,DAND6,VBCHsclerosteosis,sclerostin,SOST1,CDD,S...	Human	HEK293 Cells
	SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. SOST Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 24.2 kDa and the accession number is Q9BQB4-1.
TMPH-01178	CDA Protein, Human, Recombinant (His & Myc) CDA,Cytidine aminohydrolase,CDD,Cytidine deaminase	Human	E. coli
	CDA Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPK-00102	SOST Protein, Human, Recombinant (His & Avi) VBCHsclerosteosis,SOST1,sclerostin,SOST,CDD,DAND6,V...	Human	HEK293 Cells
	SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. SOST Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 24.2 kDa and the accession number is Q9BQB4-1.
TMPK-00989	APCDD1 Protein, Mouse, Recombinant (His) FP7019,HTS,Drapc1,HHS,Apcdd1,B7323,HYPT1	Mouse	HEK293 Cells
	APCDD1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 54.4 kDa and the accession number is Q3U128.
TMPY-03046	APCDD1 Protein, Human, Recombinant (hFc) HYPT1,B7323,adenomatosis polyposis coli down-regulated 1,HTS...	Human	HEK293 Cells
	Osteosarcoma (OS) is the most common type of bone tumor in children and adults. The expression of APCDD1, a Wnt antagonist, was reduced in OS tissues and cells compared to adjacent normal tissue and osteoblast cells, respectively. Mechanistically, this was due to increased levels of methylation in the promoter region of the APCDD1 gene. Consistently, the DNA methyltransferase inhibitor 5-AZA-dC, reduced DNA methylation in the APCDD1 promoter, and restored APCDD1 expression in OS tissue and cells...
TMPK-00311	APCDD1 Protein, Human, Recombinant (His) HHS,B7323,Apcdd1,Drapc1,HYPT1,HTS,FP7019	Human	HEK293 Cells
	APCDD1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 54.4 kDa and the accession number is Q8J025.

重组蛋白

SOST Protein, Human, Recombinant (His)

Cat.No: TMPY-00925

Species: Human

Expression System: HEK293 Cells

SOST Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05113

Species: Human

Expression System: HEK293 Cells

SOST Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01293

Species: Cynomolgus

Expression System: HEK293 Cells

SOST Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00103

Species: Human

Expression System: HEK293 Cells

CDA Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01178

Species: Human

Expression System: E. coli

SOST Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00102

Species: Human

Expression System: HEK293 Cells

APCDD1 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00989

Species: Mouse

Expression System: HEK293 Cells

APCDD1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03046

Species: Human

Expression System: HEK293 Cells

APCDD1 Protein, Human, Recombinant (His)

Cat.No: TMPK-00311

Species: Human

Expression System: HEK293 Cells

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