Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tedizolid Phosphate (TR-701FA) 是 MAO-A 和 MAO-B 抑制剂,具有抗革兰氏阳性菌的活性。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 273 | 现货 | ||
2 mg | ¥ 385 | 现货 | ||
5 mg | ¥ 647 | 现货 | ||
10 mg | ¥ 997 | 现货 | ||
25 mg | ¥ 1,660 | 现货 | ||
50 mg | ¥ 2,470 | 现货 | ||
100 mg | ¥ 3,690 | 现货 | ||
500 mg | ¥ 8,230 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 693 | 现货 |
产品描述 | Tedizolid Phosphate (TR-701FA) is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid. |
体外活性 | Tedizolid (TR-700, formerly torezolid) is the active moiety of the prodrug tedizolid phosphate (TR-701), a next-generation oxazolidinone, with high potency against Gram-positive species, including methicillin-resistant Staphylococcus aureus (MRSA)[2]. Tedizolid is 4-fold more potent than linezolid against PRSP isolates in vitro[1]. |
体内活性 | Tedizolid has excellent penetration into pulmonary epithelial lining fluid (ELF). Tedizolid phosphate administered to mice orally or intravenously is effective in vivo against systemic infection with PRSP isolates. Oral tedizolid phosphate is also effective in vivo against pneumonia induced with a PSSP strain[1]. |
别名 | TR-701FA, Torezolid phosphate, 磷酸特地唑胺 |
分子量 | 450.32 |
分子式 | C17H16FN6O6P |
CAS No. | 856867-55-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 21 mg/mL (46.6 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.2206 mL | 11.1032 mL | 22.2064 mL | 55.5161 mL |
5 mM | 0.4441 mL | 2.2206 mL | 4.4413 mL | 11.1032 mL | |
10 mM | 0.2221 mL | 1.1103 mL | 2.2206 mL | 5.5516 mL | |
20 mM | 0.111 mL | 0.5552 mL | 1.1103 mL | 2.7758 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Tedizolid Phosphate 856867-55-5 Microbiology/Virology Antibacterial Antibiotic TR-701FA inhibit Tedizolid Torezolid Phosphate Torezolid phosphate Bacterial Inhibitor 磷酸特地唑胺 inhibitor