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Search Results for " 血小板源生长因子 "

Targets Recommended: VEGFR PDGFR c-Kit

3

抑制剂 & 化合物

1

TargetMol 试剂盒

19

重组蛋白

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Cat. No.	Product Name	Form	Specificity Of Inhibition
CL0071	PDGFR inhibitor kit PDGFR inhibitor kit

TargetMol 试剂盒

PDGFR inhibitor kit

Cat.No: CL0071

Cat. No.	Product Name	Target	Signaling Pathways
T6091	CP-673451	VEGFR; PDGFR; c-Kit	Angiogenesis; Tyrosine Kinase/Adaptors
	CP673451 是选择性的血小板源生长因子受体 (PDGFR) 抑制剂，能够抑制 PDGFRα (IC50:10 nM) 和 PDGFRβ (IC50:1 nM) 的活性。
T76761	Olaratumab LY3012207,IMC-3G3	PDGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	Olaratumab(IMC-3G3) 是一种人源抗血小板衍生生长因子受体α (PDGFRα)单克隆 IgG1 抗体，具有抗肿瘤作用，可用于研究晚期软组织肉瘤。
T62872	PDGFR-IN-1
	PDGFR-IN-1 (compound 7m) 是一种口服具有活力的 PDGFR (血小板源性生长因子受体) 抑制剂，作用于 PDGFRα (IC50: 2.4 nM) 和 PDGFRβ (IC50: 0.9 nM)。。PDGFR-IN-1 表现出较强的抗肿瘤作用，并毒性较低，能够用于研究骨肉瘤。

化合物

Cat.No: T6091

Target: VEGFR, PDGFR, c-Kit

Cat.No: T76761

Synonym: LY3012207,IMC-3G3

Target: PDGFR

Cat.No: T62872

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00562	PDGF-BB Protein, Mouse, Recombinant (His) PDGFBB,PDGF-BB,血小板源生长因子	Mouse	E. coli
	Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. As growth factor，it plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival...
TMPJ-00735	PDGF-BB Protein, Human, Recombinant PDGF-BB,血小板源生长因子,PDGFBB	Human	E. coli
	Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In a...
TMPY-04976	PDGFC Protein, Mouse, Recombinant (His) platelet derived growth factor C,血小板源生长因子,AI647969,...	Mouse	Yeast
	PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyrosine kinase activity. They have roles in the regulation of many biological processes including embryonic development, angiogenesis, cell proliferation and differentiation, and contribute to the pathophysiology of some diseases, including cancer. There are two isoforms of the PDG...
TMPJ-00768	PDGF-AA Protein, Human, Recombinant (His) 血小板源生长因子,PDGF-AA,PDGFAA	Human	E. coli
	Platelet-derived growth factor subunit A (PDGFA), belongs to the PDGF/VEGF growth factor family. PDGFA is a secreted protein, stored in platelet alpha-granules and released by platelets upon wounding. PDGFA is potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. It plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. PDGFA is r...
TMPJ-00767	PDGF-AA Protein, Human, Recombinant 血小板源生长因子,PDGFAA,PDGF-AA	Human	E. coli
	Platelet-derived growth factor subunit A (PDGFA), belongs to the PDGF/VEGF growth factor family. PDGFA is a secreted protein, stored in platelet alpha-granules and released by platelets upon wounding. PDGFA is potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. It plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. PDGFA is r...
TMPY-04644	PDGFB Protein, Human, Recombinant (His) platelet-derived growth factor beta polypeptide,SSV,c-sis,SI...	Human	Yeast
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor.
TMPY-00269	PDGFC Protein, Cynomolgus, Recombinant (hFc) platelet derived growth factor C,血小板源生长因子	Cynomolgus	HEK293
	PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyrosine kinase activity. They have roles in the regulation of many biological processes including embryonic development, angiogenesis, cell proliferation and differentiation, and contribute to the pathophysiology of some diseases, including cancer. There are two isoforms of the PDG...
TMPY-02815	PDGFC Protein, Human, Recombinant (His) platelet derived growth factor C,FALLOTEIN,血小板源生长因子...	Human	Baculovirus-Insect Cells
	PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyrosine kinase activity. They have roles in the regulation of many biological processes including embryonic development, angiogenesis, cell proliferation and differentiation, and contribute to the pathophysiology of some diseases, including cancer. There are two isoforms of the PDG...
TMPY-00898	PDGFC Protein, Human, Recombinant (hFc) 血小板源生长因子,FALLOTEIN,SCDGF,platelet derived growth fa...	Human	HEK293
	PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyrosine kinase activity. They have roles in the regulation of many biological processes including embryonic development, angiogenesis, cell proliferation and differentiation, and contribute to the pathophysiology of some diseases, including cancer. There are two isoforms of the PDG...
TMPY-02251	PDGFC Protein, Mouse, Recombinant (hFc) 1110064L01Rik,PDGF-C,AI647969,血小板源生长因子,platelet der...	Mouse	HEK293
	PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyrosine kinase activity. They have roles in the regulation of many biological processes including embryonic development, angiogenesis, cell proliferation and differentiation, and contribute to the pathophysiology of some diseases, including cancer. There are two isoforms of the PDG...
TMPY-02395	PDGFB Protein, Cynomolgus, Recombinant (mFc) 血小板源生长因子,platelet-derived growth factor beta polype...	Cynomolgus	HEK293
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor.
TMPY-00455	PDGFA Protein, Canine, Recombinant (hFc) 血小板源生长因子,platelet-derived growth factor α polypepti...	Canine	HEK293
	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site.
TMPY-04838	PDGFA Protein, Mouse, Recombinant (His) platelet-derived growth factor α polypeptide,血小板源生长因子	Mouse	Yeast
	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site.
TMPY-05077	PDGFB Protein, Rhesus, Recombinant (His) platelet-derived growth factor β polypeptide,platelet-derive...	Rhesus	Yeast
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor.
TMPY-05068	PDGFA Protein, Rat, Recombinant (His) 血小板源生长因子,platelet-derived growth factor alpha polyp...	Rat	Yeast
	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site.
TMPY-05076	PDGFB Protein, Canine, Recombinant (His) platelet-derived growth factor beta polypeptide,platelet-der...	Canine	Yeast
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor.
TMPY-05075	PDGFA Protein, Canine, Recombinant (His) platelet-derived growth factor α polypeptide,血小板源生长因子	Canine	Yeast
	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site.
TMPY-04877	PDGFB Protein, Mouse, Recombinant (His) platelet-derived growth factor β polypeptide,血小板源生长因子	Mouse	Yeast
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor.
TMPY-05056	PDGFA Protein, Human, Recombinant (His) PDGF1,PDGF-A,血小板源生长因子,platelet-derived growth facto...	Human	Yeast
	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site.

重组蛋白

PDGF-BB Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00562

Species: Mouse

Expression System: E. coli

PDGF-BB Protein, Human, Recombinant

Cat.No: TMPJ-00735

Species: Human

Expression System: E. coli

PDGFC Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04976

Species: Mouse

Expression System: Yeast

PDGF-AA Protein, Human, Recombinant (His)

Cat.No: TMPJ-00768

Species: Human

Expression System: E. coli

PDGF-AA Protein, Human, Recombinant

Cat.No: TMPJ-00767

Species: Human

Expression System: E. coli

PDGFB Protein, Human, Recombinant (His)

Cat.No: TMPY-04644

Species: Human

Expression System: Yeast

PDGFC Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPY-00269

Species: Cynomolgus

Expression System: HEK293

PDGFC Protein, Human, Recombinant (His)

Cat.No: TMPY-02815

Species: Human

Expression System: Baculovirus-Insect Cells

PDGFC Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00898

Species: Human

Expression System: HEK293

PDGFC Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02251

Species: Mouse

Expression System: HEK293

PDGFB Protein, Cynomolgus, Recombinant (mFc)

Cat.No: TMPY-02395

Species: Cynomolgus

Expression System: HEK293

PDGFA Protein, Canine, Recombinant (hFc)

Cat.No: TMPY-00455

Species: Canine

Expression System: HEK293

PDGFA Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04838

Species: Mouse

Expression System: Yeast

PDGFB Protein, Rhesus, Recombinant (His)

Cat.No: TMPY-05077

Species: Rhesus

Expression System: Yeast

PDGFA Protein, Rat, Recombinant (His)

Cat.No: TMPY-05068

Species: Rat

Expression System: Yeast

PDGFB Protein, Canine, Recombinant (His)

Cat.No: TMPY-05076

Species: Canine

Expression System: Yeast

PDGFA Protein, Canine, Recombinant (His)

Cat.No: TMPY-05075

Species: Canine

Expression System: Yeast

PDGFB Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04877

Species: Mouse

Expression System: Yeast

PDGFA Protein, Human, Recombinant (His)

Cat.No: TMPY-05056

Species: Human

Expression System: Yeast

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