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Search Results for " spasmolytic "

18

抑制剂 & 化合物

10

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T5023	Propiverine hydrochloride	Others; Calcium Channel; AChR	Membrane transporter/Ion channel; Metabolism; Neuroscience; Others
	Propiverine hydrochloride 是一种痉挛剂，具有钙拮抗和抗胆碱能特性，用于研究膀胱过度活动和尿失禁。
T13523	Bronchospasmolytic agent 1	Others	Others
	Bronchospasmolytic agent 1 is a flutropium bromide compound and acts as a bronchospasmolytic agent.
T1474	Otilonium bromide Octylonium bromide,奥替溴铵,SP63	Calcium Channel; AChR	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Otilonium bromide (SP63) 是一种抗毒蕈碱药，用作解痉剂。
T67953	Elbanizine	Others	Others
	Elbanizine 显示出抗过敏、抗哮喘、抗组胺和解痉的活性。
T9420	prifinium bromide	Others	Others
	Prifinium bromide 是抗胆碱能试剂，能够改善痉挛，具有止吐效果。
T4466	Pitofenone hydrochloride Baralgin Ketone Hydrochloride,Pitophenone hydrochloride,吡托非农盐酸盐	AChE	Neuroscience
	Pitofenone hydrochloride (Pitophenone hydrochloride) 是一种能够抑制乙酰胆碱酯酶活性的解痉化合物，对于来自牛红细胞和电鳗的乙酰胆碱酯酶的Ki 分别为 36 和 45 μM。
T1197	Trimebutine maleate Debridat,Polibutin,马来酸曲美布汀	Calcium Channel; Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Trimebutine maleate (Polibutin) 是一种外周 μ、δ 和 kappa 阿片受体激动剂，用作治疗慢性和急性腹痛的解痉药物。
T5005	Eperisone hydrochloride	Others	Others
	Eperisone Hydrochloride 是一种抗痉挛试剂，用于肌肉僵硬和疼痛为特征的疾病的相关研究。它是一种中枢作用的肌肉松弛剂，抑制疼痛反射通路，具有血管扩张作用。它通过放松骨骼肌和血管平滑肌来起作用，例如减少肌张力，改善循环和抑制疼痛反射。
T1081	Naftidrofuryl oxalate 萘呋胺酯草酸盐,Nafronyl oxalate,Nafronyl oxalate salt	5-HT Receptor	GPCR/G Protein; Neuroscience
	Naftidrofuryl oxalate (Nafronyl oxalate) 是一种用于治疗外周和脑血管疾病的药物，可增加细胞氧化能力，也是一种 5-HT2 受体拮抗剂。
T0918	Trimebutine 曲美布汀,Mebutin	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Trimebutine (Mebutin) 是阿片受体激动剂，有抗毒蕈碱活性。它是解痉剂，可调节肠道和结肠运动，并通过抗毒蕈碱和弱μ-阿片受体激动剂作用缓解腹痛。
T69121	Oxpheneridine
	Oxpheneridine is a mu opioid receptor agonist that possesses the spasmolytic activity and acts as a narcotic analgesic.
T30447L	Bietamiverine dihydrochloride
	Bietamiverine dihydrochloride is a spasmolytic biochemical.
T20928	Febuprol H33,K-10033,H 33,H-33,NSC 30151
	Febuprol, a choleretic drug, stimulates bile secretion. In addition, it also has lipid-lowering (lowering blood lipid) and spasmolytic (anticonvulsant) properties.
T30703	Cantabiline sodium Hymecromone sodium,LM 94 sodium
	Cantabiline sodium is a coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in analytical chemistry for the determination of NITRIC ACID.
T25848	Naftidrofuryl
	Naftidrofuryl is used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be spasmolytic.
T25912	Oxypyrronium bromide L.D. 3055,Immetropan,LD 3055,LD3055,LD-3055
	Oxypyrronium bromide 一种含有季铵的抗胆碱能和解痉剂。在动物模型中，它抑制胃运动、迷走神经刺激或乙酰胆碱静脉注射引起的低血压；鼓索神经刺激引起的流涎和节前颈交感神经刺激引起收缩。
T33314	Methantheline Bromide Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide
	Methantheline Bromide is a synthetic spasmolytic used to relieve cramps or spasms of the stomach, bowel, and bladder. It is also useful for intestinal or gastric ulcers (peptic ulcer disease), intestinal problems, pancreatitis, gastritis, biliary dysmotil
T69071	Secoverine
	Secoverine is a selective muscarinic receptor antagonist that was studied as a neurotropic spasmolytic agent. It was shown that the drug had no nicotinolytic or antihistaminic activity, a moderate antisterotonic activity, an inhibiting effect on the noradrenaline uptake mechanism of the vas deferens and marked local anesthetic activity.

化合物

Propiverine hydrochloride

Cat.No: T5023

Target: Others, Calcium Channel, AChR

Bronchospasmolytic agent 1

Cat.No: T13523

Target: Others

Otilonium bromide

Cat.No: T1474

Synonym: Octylonium bromide,奥替溴铵,SP63

Target: Calcium Channel, AChR

Cat.No: T67953

Target: Others

prifinium bromide

Cat.No: T9420

Target: Others

Pitofenone hydrochloride

Cat.No: T4466

Synonym: Baralgin Ketone Hydrochloride,Pitophenone hydrochloride,吡托非农盐酸盐

Target: AChE

Trimebutine maleate

Cat.No: T1197

Synonym: Debridat,Polibutin,马来酸曲美布汀

Target: Calcium Channel, Opioid Receptor

Eperisone hydrochloride

Cat.No: T5005

Target: Others

Naftidrofuryl oxalate

Cat.No: T1081

Synonym: 萘呋胺酯草酸盐,Nafronyl oxalate,Nafronyl oxalate salt

Target: 5-HT Receptor

Cat.No: T0918

Synonym: 曲美布汀,Mebutin

Target: Opioid Receptor

Cat.No: T69121

Bietamiverine dihydrochloride

Cat.No: T30447L

Cat.No: T20928

Synonym: H33,K-10033,H 33,H-33,NSC 30151

Cantabiline sodium

Cat.No: T30703

Synonym: Hymecromone sodium,LM 94 sodium

Cat.No: T25848

Oxypyrronium bromide

Cat.No: T25912

Synonym: L.D. 3055,Immetropan,LD 3055,LD3055,LD-3055

Methantheline Bromide

Cat.No: T33314

Synonym: Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide

Cat.No: T69071

Cat. No.	Product Name	Target	Signaling Pathways
TN4201	Henryoside	Others	Others
	Henryoside 是一种从海棠中分离出来的天然产物。
T2S2109	Skimmianine beta-Fagarine,Skimmianin,茵芋碱,Chloroxylonine,Skimmiamine	Others	Others
	Skimmianine (Chloroxylonine) 是一种呋喹啉类生物碱，主要存在于芸香科，具有抗炎、抗痉挛和抗血小板聚集活性。它对多种癌细胞系具有细胞毒性和基因毒性。
T0525	Flopropione 夫洛丙酮,Phloropropiophenone	5-HT Receptor; Transferase	GPCR/G Protein; Metabolism; Neuroscience
	Flopropione (Phloropropiophenone) 是一种解痉剂，用作 5-HT1A 受体拮抗剂，也是儿茶酚-O-甲基转移酶抑制剂。
TWS1293	Angelic anhydride 2-Methylisocrotonic Anhydride,当归酸酐,(Z)-2-Methylbut-2-enoic anhydride	Others	Others
	Angelic anhydride ((Z)-2-Methylbut-2-enoic anhydride) 是一种脂肪酸酐，来自于不饱和碳氢酸酐。
T1391	4-Methylumbelliferone Hymecromone,4-MU,胆通	Others	Others
	4-Methylumbelliferone (Hymecromone) 是透明质酸生物合成抑制剂，显示出抗肿瘤和抗转移活性。
TN5462	Boeravinone E
	Boeravinone E exhibits spasmolytic activity.
TN3702	(-)-Corlumine	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Corlumine exhibits spasmolytic and GABA antagonist activity.
TN2276	Tokinolide B	Others	Others
	Tokinolide B may have sedative and spasmolytic properties.
TN4724	Otosenine	Others	Others
	D-Otocenine elicites low toxicity, it shows spasmolytic properties .
TN4652	Niazimicin	NF-κB; PI3K; AChR; Antifection	Microbiology/Virology; Neuroscience; NF-κB; PI3K/Akt/mTOR signaling
	Niazimicin are NF-B and PI3K inhibitors, which shows antimicrobial, hypotensive and spasmolytic activities. Niazimicin has potent antitumor promoting activity in the two-stage carcinogenesis in mouse skin using 7,12-dimethylbenz(a)anthracene (DMBA) as ini

天然产物

Cat.No: TN4201

Target: Others

Cat.No: T2S2109

Synonym: beta-Fagarine,Skimmianin,茵芋碱,Chloroxylonine,Skimmiamine

Target: Others

Cat.No: T0525

Synonym: 夫洛丙酮,Phloropropiophenone

Target: 5-HT Receptor, Transferase

Angelic anhydride

Cat.No: TWS1293

Synonym: 2-Methylisocrotonic Anhydride,当归酸酐,(Z)-2-Methylbut-2-enoic anhydride

Target: Others

4-Methylumbelliferone

Cat.No: T1391

Synonym: Hymecromone,4-MU,胆通

Target: Others

Cat.No: TN5462

Cat.No: TN3702

Target: GABA Receptor

Cat.No: TN2276

Target: Others

Cat.No: TN4724

Target: Others

Cat.No: TN4652

Target: NF-κB, PI3K, AChR, Antifection

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