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Search Results for " protozoa "

18

抑制剂 & 化合物

6

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
TP1444	Magainin 2 蛙皮素 2	Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Magainin 2是从非洲爪蟾皮肤中分离得到的一种抗菌肽。它对许多革兰氏阴性和革兰氏阳性细菌显示出抗生素活性，对原生动物也有活性。它通过优先与细菌膜中丰富的阴离子磷脂相互作用而发挥细胞毒性作用。
T1546	Nitazoxanide NSC 697855,硝唑尼特	Others; Influenza Virus; Parasite; Autophagy	Autophagy; Microbiology/Virology; Others
	Nitazoxanide (NSC-697855) 是一种广谱驱虫剂，对感染动物和人类的各种蠕虫、原生动物和肠道细菌都具有作用活性。它在无菌培养中抑制Giardia lamblia 滋养体增殖，IC50为 2.4 μM。它可研究寄生虫性胃肠炎，具有抗病毒特性。
T2279	Tizoxanide 替唑尼特,Desacetyl-nitazoxanide,TIZ	Antiviral; HIV Protease; Antibacterial; Autophagy	Autophagy; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Tizoxanide (Desacetyl-nitazoxanide) 是 Nitazoxanide 活性代谢物，有抗HIV-1的活性。Nitazoxanide 可抗细菌和多种病毒复制。
TP1839L	Dermaseptin acetate	Antibacterial	Microbiology/Virology
	Dermaseptin acetate 是一种从青蛙皮肤中分离出来的肽，在微摩尔浓度下表现出对细菌、真菌和原生动物的有效抗菌活性。
T0509	Cloxiquine 5-Chloro-8-quinolinol,氯羟喹,Dermofungin,Dermofongin,5-氯-8-羟基喹啉	Antibacterial; Antibiotic; PPAR; Parasite; Antifungal	DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Cloxiquine (Dermofongin) 具有抗菌，抗真菌和抗阿米巴虫的作用。它还可通过激活 PPARγ抑制黑素瘤细胞的生长和转移。它可研究结核病和皮肤病。
T0951	Hydroxychloroquine sulfate Acidum iopanoicum,硫酸羟基氯喹,硫酸羟氯喹,HCQ sulfate	DNA; SARS-CoV; TLR; Parasite; Autophagy	Autophagy; DNA Damage/DNA Repair; Immunology/Inflammation; Microbiology/Virology
	Hydroxychloroquine sulfate (Acidum iopanoicum) 抑制疟原虫血红素聚合酶。它还可抑制 Toll 样受体 7/9 信号传导和 SARS-CoV-2 感染。
T0195	Secnidazole RP-14539,PM-185184,塞克硝唑	Antibiotic; Parasite	Microbiology/Virology
	Secnidazole (PM-185184) 是一种具有口服活性唑类抗生素，半衰期比甲硝唑更长。它有潜力研究细菌性阴道病。
T23132	Pentamidine dihydrochloride 喷他脒二盐酸盐,MP-601205 dihydrochloride	Phosphatase; Antibacterial; Antibiotic; Parasite; Antifungal	Metabolism; Microbiology/Virology
	Pentamidine dihydrochloride (MP-601205 dihydrochloride) 是一种抗微生物剂，会干扰 DNA 的生物合成。它是选择性蛋白酪氨酸磷酸酶和再生肝磷酸酶抑制剂。它可用于冈比亚锥虫病，抗锑利什曼病和卡氏肺孢子虫肺炎的研究，有抗肿瘤活性，抗菌活性。
T19973	Acetarsone Osarsol,Vagisept,NSC 13160,NSC-13160,Amarsan,Amoebal
	Acetarsone is an antiinfective agent. Acetarsone also inhibits protozoa growth.
T71446	Kalafungin
	Kalafungin antimicrobial agent that is inhibitory in vitro against a variety of pathogenic fungi, yeasts, protozoa, gram-positive bacteria, and, to a lesser extent, gram-negative bacteria.
T19740	Narasin Monteban,甲基盐霉素,A28086A,A 28086A,A-28086A
	Narasin is a novel agent that inhibits dengue virus replication in vitro through non-cytotoxic mechanisms. It is used for the treatment of coccidiosis from a class of protozoa. It has been shown to foster the apoptosis of tumor cells.
T40928	2-Aminoflubendazole
	2-Aminoflubendazole, a metabolite of benzimidazoles (BZ), belongs to a class of drugs effective against fungi, protozoa, and helminths.
TP1839	Dermaseptin
	Dermaseptin is a peptide expressed by the frog skin glands with a potent antimicrobial activity against bacteria, fungi and protozoa.
T9233	Metronidazole acetic acid	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Metronidazole acetic acid 是 Metronidazole 的代谢产物，在细菌中具有诱变活性。Metronidazole 是硝基咪唑类抗生素，杀螨剂和抗原生动物剂。
T80281	Melimine	Parasite	Microbiology/Virology
	Melimine是一种合成的抗菌肽，由蜂毒肽和鱼精蛋白融合而成。该化合物对P. aeruginosa和S. aureus表现出抗菌活性，且具有针对细菌、真菌和原生动物的广谱抗菌性能。
T76018	Lactoferrin (17-41) (acetate)
	Lactoferrin 17-41 (Lactoferricin B) acetate 对应于牛乳铁蛋白的残基 17-41，对革兰氏阳性和革兰氏阴性细菌、病毒、原生动物和真菌等多种微生物具有抗菌活性。Lactoferrin 17-41 acetate 具有抗肿瘤活性。
T75750	Dermaseptin TFA
	Dermaseptin TFA 是从青蛙皮肤中分离出来的一种肽，在微摩尔浓度下表现出对细菌、真菌和原生动物强有力的抗菌 (antimicrobial) 活性。
T65387	Paromomycin, sulfate (1:1)
	Paromomycin (Sulfate Salt) is an aminoglycoside that is active against Gram-negative and many Gram-positive bacteria as well as some protozoa and cestodes. Paromomycin in combination with sodium stibogluconate has proven to be effective in African and Indian VL (visceral leishmaniasis) and improves survival in African VL[3]. PS (Paromomycin Sulfate) is effective for elimination of B. coli without hematological side effects[4]. The activity of phosphoglucose isomerase was slightly inhibited by 10...

化合物

Cat.No: TP1444

Synonym: 蛙皮素 2

Target: Antibacterial, Antibiotic, Antifungal

Cat.No: T1546

Synonym: NSC 697855,硝唑尼特

Target: Others, Influenza Virus, Parasite, Autophagy

Cat.No: T2279

Synonym: 替唑尼特,Desacetyl-nitazoxanide,TIZ

Target: Antiviral, HIV Protease, Antibacterial, Autophagy

Dermaseptin acetate

Cat.No: TP1839L

Target: Antibacterial

Cat.No: T0509

Synonym: 5-Chloro-8-quinolinol,氯羟喹,Dermofungin,Dermofongin,5-氯-8-羟基喹啉

Target: Antibacterial, Antibiotic, PPAR, Parasite, Antifungal

Hydroxychloroquine sulfate

Cat.No: T0951

Synonym: Acidum iopanoicum,硫酸羟基氯喹,硫酸羟氯喹,HCQ sulfate

Target: DNA, SARS-CoV, TLR, Parasite, Autophagy

Cat.No: T0195

Synonym: RP-14539,PM-185184,塞克硝唑

Target: Antibiotic, Parasite

Pentamidine dihydrochloride

Cat.No: T23132

Synonym: 喷他脒二盐酸盐,MP-601205 dihydrochloride

Target: Phosphatase, Antibacterial, Antibiotic, Parasite, Antifungal

Cat.No: T19973

Synonym: Osarsol,Vagisept,NSC 13160,NSC-13160,Amarsan,Amoebal

Cat.No: T71446

Cat.No: T19740

Synonym: Monteban,甲基盐霉素,A28086A,A 28086A,A-28086A

2-Aminoflubendazole

Cat.No: T40928

Cat.No: TP1839

Metronidazole acetic acid

Cat.No: T9233

Target: Antibacterial, Antibiotic, Parasite

Cat.No: T80281

Target: Parasite

Lactoferrin (17-41) (acetate)

Cat.No: T76018

Dermaseptin TFA

Cat.No: T75750

Paromomycin, sulfate (1:1)

Cat.No: T65387

Cat. No.	Product Name	Target	Signaling Pathways
T1079	Metronidazole Flagyl,Metronidazol,甲硝唑,Anagiardil	Apoptosis; NADPH; Hydrogenase; Antibacterial; Antibiotic; Parasite; Antifection	Apoptosis; Metabolism; Microbiology/Virology
	Metronidazole (Metronidazol) 是一种合成的硝基咪唑衍生物，具有抗原生动物和抗菌活性。
TN7254	(E,E)-Farnesol (2E,6E)-Farnesol	Others	Others
	(E,E)-Farnesol ((2E,6E)-Farnesol) 是一种由细菌、原生动物、真菌、植物和动物产生的倍半萜无环醇。(E,E)-Farnesol 可促进血管扩张。
T1304	Chlortetracycline hydrochloride Isphamycin,Chlortetracycline HCl,7-Chlorotetracycline hydrochloride,盐酸金霉素	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Chlortetracycline hydrochloride (Isphamycin) 是一种特异性钙离子载体抗生素, 抑制氨酰 tRNA 结合到核糖体。
T5S0814	Berberine hydrogen sulphate Berberine Bisulfate,硫酸氢黄连素,Umbellatine Sulfate	Antibacterial	Microbiology/Virology
	Berberine hydrogen sulphate (Umbellatine Sulfate) 是一种从几种植物中提取的生物碱，对多种微生物具有抗菌活性，包括革兰氏阳性和革兰氏阴性细菌、真菌和原生动物。
TN3033	4'-Hydroxy-2,4-dimethoxychalcone	Antibacterial; Parasite; Antifungal	Microbiology/Virology
	4'-Hydroxy-2,4-dimethoxychalcone 是红色龙血天竺葵草药树脂中的天然查尔酮衍生物。4'-Hydroxy-2,4-dimethoxychalcone 具有广泛的生物学活性，包括抗疟疾，抗细菌，抗真菌和抗原生动物活性。
T26810	Bikaverin BRN 0358013,Lycopersin
	Bikaverin is a reddish pigment produced by different fungal species with antibiotic properties against certain protozoa and fungi. Bikaverin also has antitumoral activity against different cancer cell lines.

天然产物

Cat.No: T1079

Synonym: Flagyl,Metronidazol,甲硝唑,Anagiardil

Target: Apoptosis, NADPH, Hydrogenase, Antibacterial, Antibiotic, Parasite, Antifection

Cat.No: TN7254

Synonym: (2E,6E)-Farnesol

Target: Others

Chlortetracycline hydrochloride

Cat.No: T1304

Synonym: Isphamycin,Chlortetracycline HCl,7-Chlorotetracycline hydrochloride,盐酸金霉素

Target: ribosome, Antibacterial, Antibiotic

Berberine hydrogen sulphate

Cat.No: T5S0814

Synonym: Berberine Bisulfate,硫酸氢黄连素,Umbellatine Sulfate

Target: Antibacterial

4'-Hydroxy-2,4-dimethoxychalcone

Cat.No: TN3033

Target: Antibacterial, Parasite, Antifungal

Cat.No: T26810

Synonym: BRN 0358013,Lycopersin

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