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Search Results for " postmenopausal "

10

抑制剂 & 化合物

5

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T29164	WY-47766 WY47766
	WY-47766, a proton pump inhibitor, is used potentially for the treatment of postmenopausal osteoporosis.
T1216	Diethylstilbestrol Stilbestrol,己烯雌酚,DES	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Diethylstilbestrol (DES) 是一种非甾体雌性激素，能够用于更年期和绝经后的紊乱。
T6399	AZD1981	GPR; Prostaglandin Receptor	Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation
	AZD1981 是一种有效且特异性的 CRTh2 (DP2) 受体拮抗剂，IC50为 4 nM，用于研究哮喘、绝经后、药代动力学、哮喘患者和药物相互作用等治疗和基础科学的试验。
T6739	Zoledronic Acid CGP-4244,CGP42446A,唑来膦酸,Zoledronate,CGP 42446,ZOL 446,Zometa	Apoptosis; Rho; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint
	Zoledronic Acid (ZOL 446) 是一种含氮二磷酸盐，能抑制破骨细胞的分化和凋亡，具有高效的抗骨质再吸收活性，也有抗癌作用。
T28870	Strontium Malonate NBS-101,NBS 101,NBS101
	Strontium Malonate, a calcium-sensing receptor agonist, is used potentially for the treatment of postmenopausal osteoporosis.
TP1027	Calcitonin, eel TFA (57014-02-5 free base) Thyrocalcitonin eel (TFA),Calcitonin, eel TFA
	Calcitonin,eel TFA is a thyroid hormone polypeptide that can regulate calcium homeostasis and is widely used in the study of postmenopausal osteoporosis.
T78372	Calcitonin, eel TFA Thyrocalcitonin eel TFA
	Calcitonin, eel TFA，一种甲状腺激素多肽，调节钙稳态，主要应用于绝经后骨质疏松症研究。
TP1028	Calcitonin, eel Thyrocalcitonin eel
	Calcitonin, eel is a peptide hormone that plays a crucial role in maintaining calcium balance within the body. It is extensively utilized in the scientific investigation of postmenopausal osteoporosis, a condition characterized by decreased bone density and an increased risk of fractures in women after menopause.
T77769	Menotropin Human Menopausal Gonadotrophin
	Menotropin (Human Menopausal Gonadotropin)为治疗生育障碍的激素活性药物，源自绝经后妇女的尿液提取。
T36913	17-Epiestriol
	17-Epiestriol is a metabolite of estrone .1It is formed from estroneviaa 16α-hydroxy estrone intermediate by reduction of the C-17 ketone. 17-Epiestriol binds to estrogen receptor α (ERα) and ERβ with relative binding affinities of 29 and 80 compared with 17β-estradiol .2 1.Brinton, L.A., Trabert, B., Anderson, G.L., et al.Serum estrogens and estrogen metabolites and endometrial cancer risk among postmenopausal womenCancer Epidemiol. Biomarkers Prev.25(7)1081-1089(2016) 2.Kuiper, G.G.J.M., Lemme...

化合物

Cat.No: T29164

Synonym: WY47766

Diethylstilbestrol

Cat.No: T1216

Synonym: Stilbestrol,己烯雌酚,DES

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Cat.No: T6399

Target: GPR, Prostaglandin Receptor

Zoledronic Acid

Cat.No: T6739

Synonym: CGP-4244,CGP42446A,唑来膦酸,Zoledronate,CGP 42446,ZOL 446,Zometa

Target: Apoptosis, Rho, Autophagy

Strontium Malonate

Cat.No: T28870

Synonym: NBS-101,NBS 101,NBS101

Calcitonin, eel TFA (57014-02-5 free base)

Cat.No: TP1027

Synonym: Thyrocalcitonin eel (TFA),Calcitonin, eel TFA

Calcitonin, eel TFA

Cat.No: T78372

Synonym: Thyrocalcitonin eel TFA

Calcitonin, eel

Cat.No: TP1028

Synonym: Thyrocalcitonin eel

Cat.No: T77769

Synonym: Human Menopausal Gonadotrophin

Cat.No: T36913

Cat. No.	Product Name	Target	Signaling Pathways
T1009	Estrone Oestrone,雌酮,Fluoroethyl,Aquacrine	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Estrone (Aquacrine) 是内源性雌激素的主要代表，由多种组织产生，尤其是脂肪组织。它是脂肪细胞中雄烯二酮芳构化过程的结果。
TQ0172	2''-O-Rhamnosylicariside II	Others	Others
	2''-O-Rhamnosylicariside II 是天然来源的黄酮类糖苷化合物，可能对改善绝经后骨质疏松有益处。
TJS0856	Dalbergin 黄檀素,6-Hydroxy-7-Methoxy-4-Phenylcoumarin	Others	Others
	Dalbergin (6-Hydroxy-7-Methoxy-4-Phenylcoumarin) 是一种 Dalbergia Sissoo Linn. knot wood 提取物的成分。它具有强大的抗氧化活性。
T1549	Raloxifene hydrochloride LY156758 hydrochloride,盐酸雷洛昔芬,Raloxifene HCl,LY139481 hydrochloride,Keoxifene hydrochloride,LY156758 (Keoxifene) HCl	Estrogen Receptor/ERR; Others; MAO; Estrogen/progestogen Receptor; Autophagy	Autophagy; Endocrinology/Hormones; Metabolism; Neuroscience; Others
	Raloxifene hydrochloride (LY156758 hydrochloride) 是一种选择性且可口服的雌激素受体调节剂，用于预防绝经后妇女的骨质疏松症。它对骨骼和胆固醇代谢具有雌激素激动作用，但对乳腺和子宫组织具有完全的雌激素拮抗作用。
TN4334	Isotaxiresinol	TNF	Apoptosis
	Isotaxiresinol prevents d-GalN/LPS-induced hepatic injury by inhibiting hepatocyte apoptosis through the blocking of TNF-alpha and IFN-gamma production by activated macrophages and direct inhibition of the apoptosis induced by TNF-alpha. Isotaxiresinol ma

天然产物

Cat.No: T1009

Synonym: Oestrone,雌酮,Fluoroethyl,Aquacrine

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

2''-O-Rhamnosylicariside II

Cat.No: TQ0172

Target: Others

Cat.No: TJS0856

Synonym: 黄檀素,6-Hydroxy-7-Methoxy-4-Phenylcoumarin

Target: Others

Raloxifene hydrochloride

Cat.No: T1549

Synonym: LY156758 hydrochloride,盐酸雷洛昔芬,Raloxifene HCl,LY139481 hydrochloride,Keoxifene hydrochloride,LY156758 (Keoxifene) HCl

Target: Estrogen Receptor/ERR, Others, MAO, Estrogen/progestogen Receptor, Autophagy

Cat.No: TN4334

Target: TNF

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