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Search Results for " palmitate "

26

抑制剂 & 化合物

22

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T0752	Ascorbyl palmitate L-抗坏血酸棕榈酸酯,L-Ascorbic acid 6-hexadecanoate,6-O-Palmitoyl-L-ascorbic acid,L-Ascorbyl 6-palmitate,抗坏血酸棕榈酸酯	Reactive Oxygen Species; Endogenous Metabolite	Immunology/Inflammation; Metabolism; NF-κB
	Ascorbyl palmitate (L-Ascorbic acid 6-hexadecanoate) 是由抗坏血酸和棕榈酸形成的一种酯，一种脂溶性形式的维生素 C。
T20525	Chloramphenicol palmitate	Antibacterial; Antibiotic	Microbiology/Virology
	Chloramphenicol palmitate 是一种广谱抗生素，对革兰氏阳性和革兰氏阴性细菌具有活性。 Chloramphenicol palmitate 可用于在含有氯霉素抗性基因的转化细胞中作为细菌选择剂的研究。
T15102	Dexamethasone palmitate 地塞米松棕榈酸酯,DXP	Glucocorticoid Receptor	Endocrinology/Hormones
	Dexamethasone palmitate (DXP) (DXP) 是 Dexamethasone 的前药。Dexamethasone 是糖皮质激素受体激动剂。与Dexamethasone 相比， DXP 对糖皮质激素受体的亲和力低 47 倍。DXP 显示出抗炎活性。
T20503	Elfacos EHP 2-ethylhexyl palmitate,棕榈酸辛酯	Others	Others
	Elfacos EHP (2-ethylhexyl palmitate) 是一种衍生自 2-乙基己醇和棕榈酸的脂肪酸酯，可用作化妆品配方。
T6449	Clindamycin palmitate hydrochloride Cleocin Pediatric,盐酸克林霉素棕榈酸酯,Clindamycin palmitate HCl	Antibacterial; Antibiotic	Microbiology/Virology
	Clindamycin palmitate hydrochloride (Clindamycin palmitate HCl) 是克林霉素和棕榈酸酯的盐酸盐，是一种林可酰胺抗生素。
T19950	Paliperidone Palmitate RO 92670,RO92670,RO-92670
	Paliperidone is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class of medications. Paliperidone has an antagonist effect at α1 and α2 adrenergic receptors and at H1 histamine receptors. In addition, it binds with dopamine and
T33870	Palmitoyllactic acid Lactic acid,palmitate
	Palmitoyllactic acid is a long-chain fatty acid.
T66561	2-Chloroethyl palmitate
	2-Chloroethyl palmitate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66561，CAS号为 929-16-8。
T71810	Thiamphenicol palmitate
	Thiamphenicol palmitate is a Prodrug of Thiamphenicol, inhibiting the 50S subunit of the bacterial ribosome and protein translation.
T66371	2-Hydroxyethyl palmitate
	2-Hydroxyethyl palmitate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66371，CAS号为 4219-49-2。
T68642	Kahweol palmitate
	Kahweol palmitate is a semi-synthetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing cell cycle arrest and apoptosis in oral squamous cell carcinoma cells, preventing aflatoxin B1-induced DNA adduct formation, and suppressing H2O2-induced DNA damage and oxidative stress.
T83314	4-Methylumbelliferyl palmitate
	4-Methylumbelliferyl palmitate 是用于测量人白细胞中酸性脂肪酶的优良荧光探针。该化合物的荧光特性受pH值和溶剂类型的显著影响。在近中性水溶液中，4-Methylumbelliferyl palmitate 以中性形态存在，并在445 nm发射较强荧光；而在微弱碱性环境中，则以阴离子形态存在，同样在445 nm处展现较强的荧光。
T77788	Palmitic acid sodium Sodium palmitate,Palmitic acid sodium
	Palmitic acid sodium（Sodium palmitate）是饱和脂肪酸的一种，其在脂肪酸合成中形成。Palmitic acid sodium 能促进多种细胞系脂肪生成及细胞脂肪变性。
T10004	Palmitodiolein Triglyceride POO,1,2-Dioleoyl-3-palmitoylglycerol,Glycerol dioleate palmitate	Others	Others
	Palmitodiolein is a triacylglycerol existed in vegetable oils.
T4535	Etomoxir sodium salt (R)-(+)-乙莫克舍钠盐,(R)-Etomoxir sodium salt,Na salt,Etomoxir	Apoptosis; Others	Apoptosis; Others
	Etomoxir sodium salt ((R)-Etomoxir sodium salt) 是一种肉碱棕榈酰转移酶 1a (CPT-1a) 抑制剂，可以阻断脂肪酸合成。Etomoxir sodium salt 具有抗肿瘤活性。
T37191	Mu-6S-Palm-β-Glc
	Mu-6S-Palm-β-Glc is a fluorogenic substrate of palmitoyl-protein thioesterase (PPT, also known as CLN1), a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. Mu-6S-Palm-β-Glc is cleaved by PPT/CLN1 to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM...
T17180	TVB-3166	Apoptosis; Others; Fatty Acid Synthase	Apoptosis; Metabolism; Others
	TVB-3166 是一种口服有效的，可逆和选择性脂肪酸合成酶 (FASN) 抑制剂，对于 FASN 和细胞棕榈酸酯合成的IC50分别为 42 nM 和 81 nM。它诱导细胞凋亡，抑制体内异种移植肿瘤生长。
T37299	L-Palmitoylcarnitine chloride
	Palmitoyl-L-carnitine is a naturally occurring long-chain acylcarnitine and the L-enantiomer of palmitoyl-DL-carnitine . In cells, palmitoyl-L-carnitine is transported into mitochondria via carnitine palmitoyl transferase II to deliver palmitate for fatty acid oxidation and energy production. It also inhibits lecithin:cholesterol acyltransferase activity in rat, but not human, plasma when used at a concentration of 500 μM. In vivo, palmitoyl-L-carnitine increases intestinal absorption of the ant...
T35364	2-Bromohexadecanoic acid 2-BP,2-溴十六烷酸,2-bromopalmitate,2-Bromohexadecanoic acid	Others	Others
	2-Bromohexadecanoic acid (2-BP) 是一种不可代谢的棕榈酸酯类似物，可用作棕榈酰化抑制剂。它直接且不可逆地抑制所有 DHHC (Asp-His-His-Cys) 蛋白的棕榈酰转移酶活性。
T17181	TVB-3664	Fatty Acid Synthase	Metabolism
	TVB-3664 是一种具有口服具有活力的、选择性的、可逆的、具有高生物利用度的脂肪酸合酶抑制剂，其对人和老鼠棕榈酸酯合成的IC50分别为 18 nM 和 12 nM。可显著抑制微管蛋白棕榈酰化和 mRNA 表达。
T4535L	Etomoxir (R)-(+)-Etomoxir	Antioxidant; CPT	Metabolism; oxidation-reduction
	Etomoxir 是肉碱棕榈酰转移酶 1a （CPT-1a）抑制剂，通过抑制 CPT-1a 来抑制脂肪酸氧化，且抑制人、大鼠和豚鼠中棕榈酸酯的氧化。Etomoxir 对腺嘌呤核苷酸转位酶有抑制作用，可通过破坏CoA稳态来抑制巨噬细胞极化。
T35444	1-Pentadecanoyl-rac-glycerol
	1-Pentadecanoyl-rac-glycerol is a monoacylglycerol that contains pentadecanoic acid at the sn-1 position. It has been found in wheat bran extracts.1 1-Pentadecanoyl-rac-glycerol levels are increased in a HepaRG cell-based model of hepatic steatosis induced by BSA-conjugated palmitate.2 \|1. Prinsen, P., Gutiérrez, A., Faulds, C.B., et al. Comprehensive study of valuable lipophilic phytochemicals in wheat bran. J. Agric. Food Chem. 62(7), 1664-1673 (2014).\|2. Brown, M.V., Compton, S.A., Milburn, M...
T39423	Palmitic acid-13C sodium
	Sodium palmitate-13C is the 13C-labeled variant of palmitic acid, a long-chain saturated fatty acid prevalent in animals and plants. This compound has been shown to induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer-binding protein homologous protein (CHOP) in mouse granulosa cells.
T35810	C24 dihydro Ceramide (d18:0/24:0) Cer(d18:0/24:0)
	C24 dihydro Ceramide is a sphingolipid that has been found in the stratum corneum of human skin.[1] It is found in higher concentrations in female sebum compared to male sebum.[2] C24 dihydro Ceramide levels positively correlate with cytotoxicity in CCRF-CEM, MOLT-4, COG-LL-317h, and COG-LL-332h T cell acute lymphoblastic leukemia (ALL) cell lines.[4] Levels of C24 dihydro ceramide are increased by 149.49-fold in dihydroceramide desaturase 1 (DEGS1) knockdown UM-SCC-22A human head and neck squam...
T36149	13C C16 Sphingomyelin (d18:1/16:0)
	13C C16 Sphingomyelin is an isotopically enriched form of C16 sphingomyelin with carbon-13 occurring on the fatty acid portion. It is intended for use as an internal standard for the quantification of C16 sphingomyelin by GC- or LC-MS. C16 Sphingomyelin is a form of sphingomyelin containing palmitate (16:0) at the variable acylation position. It is the most common form of sphingomyelin found in eggs and is less abundant in the brain and in milk. C16 Sphingomyelin interacts with cholesterol in or...
T36130	22(S)-hydroxy Cholesterol 22(S)-hydroxy Cholesterol,22β-hydroxy Cholesterol
	22(S)-hydroxy Cholesterol is a synthetic oxysterol and a modulator of the liver X receptor (LXR). [1] t prevents monocyte chemoattractant protein 1 (MCP-1) expression induced by the LXR agonist GW 3965 in primary hepatocytes and downregulates mRNA expression of the LXR target genes CD36, ACSL1, and SCD-1 in human myotubes. It decreases triacylglycerol and diacylglycerol synthesis from labeled palmitate and acetate, respectively, in human myoblasts by 50% when used at a concentration of 10 uM. 22...

化合物

Ascorbyl palmitate

Cat.No: T0752

Synonym: L-抗坏血酸棕榈酸酯,L-Ascorbic acid 6-hexadecanoate,6-O-Palmitoyl-L-ascorbic acid,L-Ascorbyl 6-palmitate,抗坏血酸棕榈酸酯

Target: Reactive Oxygen Species, Endogenous Metabolite

Chloramphenicol palmitate

Cat.No: T20525

Target: Antibacterial, Antibiotic

Dexamethasone palmitate

Cat.No: T15102

Synonym: 地塞米松棕榈酸酯,DXP

Target: Glucocorticoid Receptor

Cat.No: T20503

Synonym: 2-ethylhexyl palmitate,棕榈酸辛酯

Target: Others

Clindamycin palmitate hydrochloride

Cat.No: T6449

Synonym: Cleocin Pediatric,盐酸克林霉素棕榈酸酯,Clindamycin palmitate HCl

Target: Antibacterial, Antibiotic

Paliperidone Palmitate

Cat.No: T19950

Synonym: RO 92670,RO92670,RO-92670

Palmitoyllactic acid

Cat.No: T33870

Synonym: Lactic acid,palmitate

2-Chloroethyl palmitate

Cat.No: T66561

Thiamphenicol palmitate

Cat.No: T71810

2-Hydroxyethyl palmitate

Cat.No: T66371

Kahweol palmitate

Cat.No: T68642

4-Methylumbelliferyl palmitate

Cat.No: T83314

Palmitic acid sodium

Cat.No: T77788

Synonym: Sodium palmitate,Palmitic acid sodium

Cat.No: T10004

Synonym: Triglyceride POO,1,2-Dioleoyl-3-palmitoylglycerol,Glycerol dioleate palmitate

Target: Others

Etomoxir sodium salt

Cat.No: T4535

Synonym: (R)-(+)-乙莫克舍钠盐,(R)-Etomoxir sodium salt,Na salt,Etomoxir

Target: Apoptosis, Others

Mu-6S-Palm-β-Glc

Cat.No: T37191

Cat.No: T17180

Target: Apoptosis, Others, Fatty Acid Synthase

L-Palmitoylcarnitine chloride

Cat.No: T37299

2-Bromohexadecanoic acid

Cat.No: T35364

Synonym: 2-BP,2-溴十六烷酸,2-bromopalmitate,2-Bromohexadecanoic acid

Target: Others

Cat.No: T17181

Target: Fatty Acid Synthase

Cat.No: T4535L

Synonym: (R)-(+)-Etomoxir

Target: Antioxidant, CPT

1-Pentadecanoyl-rac-glycerol

Cat.No: T35444

Palmitic acid-13C sodium

Cat.No: T39423

C24 dihydro Ceramide (d18:0/24:0)

Cat.No: T35810

Synonym: Cer(d18:0/24:0)

13C C16 Sphingomyelin (d18:1/16:0)

Cat.No: T36149

22(S)-hydroxy Cholesterol

Cat.No: T36130

Synonym: 22(S)-hydroxy Cholesterol,22β-hydroxy Cholesterol

Cat. No.	Product Name	Target	Signaling Pathways
T1059	Retinyl palmitate Retinol palmitate,Vitamin A palmitate,Retinyl (Vitamin A) Palmitate,维生素A棕榈酸酯	Others; Endogenous Metabolite	Metabolism; Others
	Retinyl palmitate (Vitamin A palmitate) 是酯化的视黄醇，是表皮中维生素 A 的主要形式，在药品和化妆品中有广泛应用。
T5074	Cholesteryl palmitate	Others; Endogenous Metabolite	Metabolism; Others
	Cholesteryl palmitate 是一种慢性间质性肺炎的有用预后生物标志物。
T2S0157	Methyl palmitate Methyl hexadecanoate,软脂酸甲酯,十六烷酸甲酯,Palmitic acid methyl ester,十六酸甲酯	Others	Others
	Methyl palmitate (Palmitic acid methyl ester) 是存在于绿色核桃壳中的杀螨化合物，具有抗炎和抗纤维化作用，可抑制吞噬活性和免疫应答。
TN1107	Lupeol palmitate 蛇菰素B,羽扇豆醇棕榈酸酯	Others	Others
	Lupeol palmitate 是一种可从 Ligularia songarica 中提取的天然化合物，具有抗溃疡活性和肠胃保护作用。
T2S0164	Ethyl palmitate 棕榈酸乙酯,Palmitic acid ethyl ester,Ethyl cetylate,Ethyl hexadecanoate	Others	Others
	Ethyl palmitate (Palmitic acid ethyl ester) 是一种脂肪酸乙酯 (FAEE)。在人受试者食用酒精后，它的合成量比其他 FAEE 更多。它可用作头发和皮肤调理剂。
TN2554	1-Monopalmitin Glyceryl palmitate	Apoptosis	Apoptosis
	1-Monopalmitin (Glyceryl palmitate) 是一种从Mougeotia nummuloides 和 Spirulina major 提取出来的小分子化合物，具有潜在的抗肿瘤活性，抑制A549和SPC-A1细胞增殖，诱导G2/M阻滞和半胱天冬酶依赖性细胞凋亡。
T40424	9-cis-Vitamin A palmitate 9-cis-Vitamin A palmitate,9-cis-Retinyl palmitate
	9-cis-Vitamin A palmitate (9-cis-Retinyl palmitate) is a 9-cis isomer resulting from the interaction of vitamin A palmitate in corn flakes. It exhibits a biological activity of 26% compared to all-trans-vitamin A palmitate, which is known to be the most biologically active form of vitamin A.
TN3383	α-Amyrin palmitate alpha-Amyrin palmitate	PKA	Tyrosine Kinase/Adaptors
	alpha-Amyrin palmitate is antiarthritic in the adjuvant model of arthritis in rats. alpha-Amyrin palmitate is a potent non-competitive inhibitor of chymotrypsin (Ki=6 microM), it also shows weak cytotoxicity against the A2780 human ovarian cancer cell line.
TN3510	Betulin palmitate	Others	Others
	Betulin palmitate 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3510，CAS号为 582315-55-7。
TN5987	Betulinic acid palmitate
	Betulinic acid palmitate 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5987，CAS号为 19833-15-9。
TN4253	Ingenol 3-palmitate	Others	Others
	Ingenol-3-palmitate shows irritant and cocarcinogenic activity on mouse ear and on mice back skin.
TN5032	Sitosteryl palmitate	Others	Others
	Sitosteryl palmitate是一种天然产物，属于虎耳草科落新妇属，其产品编号为 TN5032，CAS号为 2308-85-2。Sitosteryl palmitate可用作对照参考。
TN4252	Ingenol 20-palmitate	Others	Others
	Ingenol 20-palmitate is a natural product from Euphorbia sieboldiana.
T20006	Isopropyl palmitate EINECS 205-571-1,Isopropyl hexadecanoate,BRN 1786567,AI3-05733,Emcol-IP,HSDB 2647
	Isopropyl palmitate is the isopropyl alcohol and palmitic acid ester. It is a moisturizer, emollient, anti-static agent, and thickening agent.
TN2590	11alpha,12alpha-Oxidotaraxerol palmitate	Others	Others
	11alpha,12alpha-Oxidotaraxerol palmitate shows selective cytotoxicity against HCT-8, Bel-7402, BGC-823, A549 and A2780.
TN4011	Erythrodiol 3-palmitate	Others	Others
	Erythrodiol 3-palmitate has antitumor activity, it inhibited the proliferation of K562 cells with the inhibition rate of 47% at 100 ug/mL.
T81395	Progenin III palmitate
	Progenin III palmitate是从Dioscorea cayenensis rhizomes中提取的类固醇糖苷酯。
T83450	14-Benzoylmesaconine-8-palmitate
	14-Benzoylmesaconine-8-palmitate（化合物4）为A. toxicum中含有的脂生物碱。
T75679	13-cis-Vitamin A palmitate
	13-cis-Vitamin A palmitate（13-cis-Retinyl palmitate）是一种在玉米片中发现的维生素A棕榈酸酯的13-顺式异构体。其生物活性相当于全反式维生素A棕榈酸酯（维生素A具生物活性形式）的75%。
TWO2727	Propane-1,2,3-triyl tripalmitate Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate,三棕榈酸甘油酯	Others; Endogenous Metabolite	Metabolism; Others
	Propane-1,2,3-triyl tripalmitate (Glycerol Tripalmitate) 是内源性代谢产物的一种。
TN4773	Zeaxanthin dipalmitate 玉米,Physalien	Others	Others
	Zeaxanthin dipalmitate 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4773，CAS号为 144-67-2。
T83558	(3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone
	(3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone（化合物3）是从丹参（Salvia miltiorrhiza）根提取的棕榈酸盐。该化合物展现出抗癌活性，对于不同的人类癌症细胞系具有显著的抑制效果，其DC50值分别为：HeLa细胞系25.5 μg/mL、HepG2细胞系37.5 μg/mL以及OVCAR-3细胞系30.2 μg/mL。

天然产物

Retinyl palmitate

Cat.No: T1059

Synonym: Retinol palmitate,Vitamin A palmitate,Retinyl (Vitamin A) Palmitate,维生素A棕榈酸酯

Target: Others, Endogenous Metabolite

Cholesteryl palmitate

Cat.No: T5074

Target: Others, Endogenous Metabolite

Methyl palmitate

Cat.No: T2S0157

Synonym: Methyl hexadecanoate,软脂酸甲酯,十六烷酸甲酯,Palmitic acid methyl ester,十六酸甲酯

Target: Others

Lupeol palmitate

Cat.No: TN1107

Synonym: 蛇菰素B,羽扇豆醇棕榈酸酯

Target: Others

Ethyl palmitate

Cat.No: T2S0164

Synonym: 棕榈酸乙酯,Palmitic acid ethyl ester,Ethyl cetylate,Ethyl hexadecanoate

Target: Others

Cat.No: TN2554

Synonym: Glyceryl palmitate

Target: Apoptosis

9-cis-Vitamin A palmitate

Cat.No: T40424

Synonym: 9-cis-Vitamin A palmitate,9-cis-Retinyl palmitate

α-Amyrin palmitate

Cat.No: TN3383

Synonym: alpha-Amyrin palmitate

Target: PKA

Betulin palmitate

Cat.No: TN3510

Target: Others

Betulinic acid palmitate

Cat.No: TN5987

Ingenol 3-palmitate

Cat.No: TN4253

Target: Others

Sitosteryl palmitate

Cat.No: TN5032

Target: Others

Ingenol 20-palmitate

Cat.No: TN4252

Target: Others

Isopropyl palmitate

Cat.No: T20006

Synonym: EINECS 205-571-1,Isopropyl hexadecanoate,BRN 1786567,AI3-05733,Emcol-IP,HSDB 2647

11alpha,12alpha-Oxidotaraxerol palmitate

Cat.No: TN2590

Target: Others

Erythrodiol 3-palmitate

Cat.No: TN4011

Target: Others

Progenin III palmitate

Cat.No: T81395

14-Benzoylmesaconine-8-palmitate

Cat.No: T83450

13-cis-Vitamin A palmitate

Cat.No: T75679

Propane-1,2,3-triyl tripalmitate

Cat.No: TWO2727

Synonym: Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate,三棕榈酸甘油酯

Target: Others, Endogenous Metabolite

Zeaxanthin dipalmitate

Cat.No: TN4773

Synonym: 玉米,Physalien

Target: Others

(3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone

Cat.No: T83558

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