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Cat. No. | Product Name | Target | Signaling Pathways |
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TP2280 |
ovalbumin (324-338) [Gallus gallus]/[Coturnix coturnix]
|
Others | Others |
Ovalbumin is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin is an important protein in several different areas of research, including general studies of protein structure and properties. Ovalbumin is used for studies | |||
T80099 |
Ovalbumin (154-159)
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Angiotensin-converting Enzyme (ACE) | Metabolism |
Ovalbumin (154-159)为卵清蛋白片段,同时作为一种有效的血管紧张素转换酶 (ACE) 抑制剂,适用于高血压研究。 | |||
T4657 |
WHI-P97
4-(3',5'-二溴-4-羟基苯基)氨基-6,7-二甲氧基喹唑啉 |
JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
WHI-P97 是一种选择性 JAK-3抑制剂,可用于预防过敏性哮喘的研究。 | |||
T33647L |
Nesosteine Lithium
Nesosteine Lithium(84233-61-4 Free baes) |
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Nesosteine Lithium 是一种新型的粘液调节剂,对豚鼠 Herxheimer 微休克具有抑制作用且抑制卵清蛋白诱导的组胺在致敏动物气管中的释放。Nesosteine Lithium 能够保护致敏动物免受卵清蛋白诱导的支气管痉挛但对组胺和乙酰胆碱诱导的支气管痉挛无效。 | |||
TP1591L |
OVA G4 peptide acetate(148274-82-2 free base)
SIIGFEKL acetate |
Others | Others |
OVA G4 peptide acetate(148274-82-2 free base) (SIIGFEKL acetate) 是激动剂卵清蛋白 (OVA) 肽 (257-264) SIINFEKL 的变体。 OVA 肽是卵清蛋白的 I 类 (Kb) 限制性肽表位,由 I 类 MHC(主要组织相容性复合物)分子 H-2Kb(小鼠 MHC I 类基因)呈递。 | |||
TP1327L |
OVA Peptide 257-264 2TFA (138831-86-4 free base)
OVA Peptide 257-264 2TFA 1262751-08-5(TFA-2TFA) |
Others | Others |
OVA Peptide 257-264 2TFA (138831-86-4 free base) 是 OVA 的 I 类 (Kb) 限制性肽表位,OVA 是卵清蛋白的八聚体肽,由 I 类 MHC 分子 H-2Kb 呈递。 | |||
TP1591 |
OVA G4 peptide
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G4 peptide (SIIGFEKL) is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC). | |||
TP1652 |
OVA G4 peptide TFA (148274-82-2 free base)
OVA G4 peptide TFA |
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OVA G4 peptide TFA is an TFA salt form of OVA G4 peptide. G4 peptide (SIIGFEKL) is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC). | |||
T37722 |
Diprovocim-1
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Diprovocim-1 is an agonist of the toll-like receptor 1/2 heterodimer.1It induces TNF-α release in THP-1 cells (EC50= 110 pM), an effect that can be inhibited by anti-TLR1 or anti-TLR2 antibodies. Diprovocim-1 (10 mg/kg) increases the production of ovalbumin-specific IgG1 in wild-type, but notTLR2-/-, mice sensitized to ovalbumin.2It also enhances anti-PD-L1 antibody-induced activation of cytotoxic T lymphocytes, reduction of tumor growth, and increases in survival in a B16/F10 murine melanoma mo... | |||
T39005 |
OVA (55-62)
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OVA 55-62 is a truncated peptide derived from the ovalbumin (OVA) antigen, specifically designed to bind to the H2-Kb mouse major histocompatibility complex (MHC) class I molecule. | |||
T7619 |
OVA Peptide(257-264)
OVA Peptide 257-264,OVA Peptide 257-264 (2TFA) |
Others | Others |
OVA Peptide(257-264) 是 OVA 的 I 类 (Kb)-限制性肽表位,其中OVA 是一种来自卵清蛋白的八聚体肽,由 I 类 MHC 分子 H-2Kb 所呈递。 | |||
TP1327 |
OVA Peptide(257-264) TFA
OVA Peptide (257-264) TFA |
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OVA Peptide (257-264) TFA, an octameric peptide epitope from ovalbumin, is presented by the class I MHC molecule, H-2Kb, showcasing a class I (Kb)-restricted profile. | |||
T78000 |
OVA Peptide (323-339)
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OVA Peptide (323-339) 是卵清蛋白(OVA)的T和B细胞表位,对BALB/c小鼠的瞬时超敏反应生成与发展至关重要。 | |||
T71329 |
Theophylline-d6
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Theophylline-d6 is intended for use as an internal standard for the quantification of theophylline by GC- or LC-MS. Theophylline is an inhibitor of phosphodiesterase. It is also an adenosine A1 and A2 receptor antagonist. Theophylline induces relaxation of isolated cat bronchial smooth muscle segments precontracted with acetylcholine. It inhibits ovalbumin-induced increases in bronchoalveolar lavage fluid (BALF) eosinophil infiltration in an ovalbumin-sensitized mouse model of allergic asthma. F... | |||
T81589 |
OVA-A2 Peptide
SAINFEKL, OVA (257-264) Variant |
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OVA-A2 Peptide(SAINFEKL, OVA (257-264) Variant)是具备生物活性的A2肽(SAINFEKL)变体,具有抗原特性。 | |||
TP1339 |
OVA Peptide 323-339
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OVA Peptide (323-339) represents a T and B cell epitope of Ovalbumin (Ova), which play an important role in the development and development of immediate hypersensitivity in BALB/c mice. | |||
T38350 |
TAS 205
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TAS 205 is an inhibitor of hematopoietic prostaglandin D synthase (H-PGDS; IC50= 55.8 nM).1It is selective for H-PGDS over lipocalin-type PGDS (L-PGDS) at 100 μM, as well as over enzyme and receptor panels at 10 μM. TAS 205 inhibits production of prostaglandin D2induced by A23187 in KU812 human and RBL-2H3 rat basophils with IC50values of 78.3 and 181.3 nM, respectively. It inhibits ovalbumin-induced nasal lavage fluid eosinophil infiltration and late-phase nasal obstruction in an ovalbumin-sens... | |||
T81590 |
OVA peptide
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OVA peptide,主要源于鸡蛋清,作为I类MHC(主要组织相容性复合体)分子H-2Kb(小鼠MHC的I类基因)所呈递的特定卵白蛋白Kb限制性表位。在过敏性研究领域,OVA peptide具有广泛应用。 | |||
T37604 | ITK inhibitor | ||
Interleukin-2-inducible T cell kinase (ITK) is a non-receptor tyrosine kinase expressed in T cells, NKT cells and mast cells which plays a crucial role in regulating the T cell receptor (TCR), CD28, CD2, chemokine receptor CXCR4, and FcepsilonR-mediated signaling pathways. ITK inhibitors can be used for the treatment of inflammation and immune-mediated disorders. ITK inhibitor (N-[5-[[3-[(4-Acetylpiperazin-1-yl)carbonyl]-4-methyl-6-methoxy-phenyl]thio]thiazol-2-yl]-4-(N-1,2-dimethylpropylaminome... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T12500 |
Platycoside E
Platycodin E,桔梗苷E |
Others | Others |
Platycoside E (Platycodin E) 是一种桔梗皂苷元型皂苷,从桔梗的根中分离获得,能够促进 ovalbumin 免疫小鼠中血清 OVA 特异性IgG2a 和IgG2b 抗体的产生。它具有溶血活性和佐剂潜力。 | |||
T64744 |
Ovalbumins
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Endogenous Metabolite | Metabolism |
Ovalbumins 是蛋清中的主要蛋白质。Ovalbumins 具有多种生物活性,如降压、抗菌、抗癌、抗氧化和免疫调节活性。Ovalbumins 是雌激素或孕酮处理的输卵管中合成的丰富的蛋白质。Ovalbumins 通常用作研究激素控制该组织中基因表达的标志物。 | |||
TMA1570 |
Sappanone A
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NF-κB; Nrf2 | Immunology/Inflammation; NF-κB |
Sappanone A 是一种高异黄烷酮,通过调节 Nrf2 和 NF-κB 表现出抗炎作用。Sappanone A 可以减轻卵清蛋白引起的哮喘中的过敏性气道炎症。 | |||
T4S2164 |
Narirutin
Naringenin-7-O-rutinoside,Isonaringin,芸香柚皮苷,柚皮芸香苷 |
Others; Antibacterial | Microbiology/Virology; Others |
Narirutin (Naringenin-7-O-rutinoside) 是从Citrus unshiu 中分离的活性成分之一,具有抗氧化和抗炎活性。它是一种具有抗结核效力的shikimate 激酶抑制剂。 | |||
TN2974 |
3-O-Methylquercetin tetraacetate
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IL Receptor; TNF; PDE | Apoptosis; Immunology/Inflammation; Metabolism |
Quercetin 3-O-methyl ether is a potent phosphodiesterase (PDE)3/4 inhibitor, it has potential for treating asthma against ovalbumin-induced airway hyperresponsiveness. | |||
TN4819 | (-)-Praeruptorin A | ATPase; IL Receptor; Calcium Channel; P-gp | Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience |
(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis;it also can significantly suppress airway inflammation and airway remodeling induced by ovalbumin challenge, and is a potential candidate for the treatment of asthma. (-)-Praeruptorin A resensitizes Pgp-mediated MDR (Pgp-MDR) cancer cells to cancer drugs. |