15
2
Cat. No. | Product Name | Target | Signaling Pathways |
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T7656 |
Apelin-13
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Apelin-13 是存在于中枢和外周神经系统由13个氨基酸组成的多肽序列,是 G 蛋白偶联受体angiotensin II protein J (APJ) 的内源性配体,对 APJ 的 EC50 值为 0.37 nM。Apelin-13 具有扩张血管和降压活性,可用于研究 2 型糖尿病综合征。 | |||
T60437 |
PNU-282987 free base
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PNU-282987 (free base) (Compound C7) 是 α7 烟碱乙酰胆碱受体 (nAChR) 的有效激动剂 (EC50 = 154 nM), 也是5-HT3受体的功能性拮抗剂 (IC50 = 4541 nM)。PNU-282987 (free base) 可用于研究中枢和周围神经系统[1]。 | |||
T28335 |
PD 140376
PD-140376,PD140376 |
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PD 140376 is a highly selective antagonist radioligand for the cholecystokinin(B)-gastrin receptor in guinea pig gastric mucosa & cerebral cortex in the peripheral and central nervous systems. | |||
T33653 |
Neurokinin A (4-10), nle(10)-
10-Nle-neurokinin A (4-10) |
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Neurokinin A (4-10), nle(10)- is a neurologically active peptide translated from the pre-protachykinin gene. Neurokinin A has many excitatory effects on mammalian nervous systems and on the mammalian inflammatory and pain responses. | |||
T82292 |
Gluten Exorphin A5
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Gluten Exorphin A5是一种小麦麸质的片段,它在周围神经系统和中枢神经系统中显示出具有神经保护的多样作用。 | |||
T0218 |
Biperiden
Bipariden,Akineton,KL 373,比哌立登,Biperidine |
AChR | Neuroscience |
Biperiden (Bipariden) 是中枢 M1胆碱受体阻断剂,有抗帕金森症活性。 | |||
TP1681 |
Neuropeptide Y (22-36)
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Neuropeptide Y (22-36), a 15 amino acid peptide, is a fragment of Neuropeptide Y.Neuropeptide Y (NPY) is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems. N | |||
TP2194 |
Neuropeptide Y (scrambled)
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Others | Others |
Neuropeptide Y (NPY) is a 36-amino acid neuropeptide that exerts its activity via G-protein-coupled receptors. NPY is widely distributed in the peripheral and central nervous systems. It modulates a variety of physiological processes, e.g. the central reg | |||
TP1130 |
β-CGRP, human
CGRP-II (Human),Human β-CGRP |
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β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascular and nervous systems. β-CGRP contains a disulphide bridge at the N-terminus, a C-terminal phenylal | |||
T72755 | GPR35 agonist 3 | ||
GPR35 agonist3,一种合成GPR35激动剂,EC50为1.4 μM。适用于胃癌、2型糖尿病、心血管疾病及免疫与周围神经系统研究。 | |||
T38283 |
Tetracosanoyl-sulfatide
C24 3'-sulfo Galactosylceramide (d18:1/24:0) |
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Tetracosanoyl-sulfatide is an endogenous sulfated glycolipid, which are also known as sulfatides . Tetracosanoyl-sulfatide is the major sulfatide in mature myelin in the central and peripheral nervous systems. Levels of Tetracosanoyl-sulfatide are elevated in plasma derived from patients with metachromatic leukodystrophy, a disorder characterized by arylsulfatase A deficiency, leading to sulfatide accumulation. Unlike C24:1 3'-sulfo galactosylceramide, it does not induce an immune response in mo... | |||
T80685 |
γ-Bag cell peptide
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γ-袋细胞肽,一种肽类化合物,靠近卵激素原N末端区域定位,能在胰岛素促进下释放其囊泡内容。该肽在中枢及周围神经系统研究中具有应用价值。 | |||
T63183 |
RET-IN-9
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RET-IN-9 是一种 RET 的有效抑制剂。其中 RET 激酶是一种单通道跨膜受体酪氨酸激酶,在肾脏和肠神经系统的发育以及维持神经、内分泌、造血和男性生殖系统的体内平衡中发挥着重要作用。RET-IN-9 具有潜力进行 RET 相关疾病的研究(包括非小细胞肺癌和甲状腺髓样癌)。 | |||
T81182 |
Secretin (swine)
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Secretin (swine)为源自猪的神经内分泌激素,由十二指肠黏膜S细胞产生,具有27个氨基酸的多肽结构,并针对分泌素受体起作用。此激素在各类成熟肠内分泌细胞亚群中表达,受脂肪酸的促进。它主要激发胰腺释放水和碳酸氢盐,同时在消化系统、中枢神经系统和能量代谢方面具有广泛应用。 | |||
T35639 |
Sulfatides (bovine) (sodium salt)
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Sulfatides are endogenous sulfoglycolipids with various biological activities in the central and peripheral nervous systems, pancreas, and immune system. They are produced from the combination of ceramide and UDP-galactose in the endoplasmic reticulum followed by sulfation in the Golgi apparatus. The ceramide portion contains variable fatty acid chain lengths, which are tissue- and pathology-dependent. Sulfatides are primarily found in the myelin sheath of oligodendrocytes and Schwann cells, wit... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T3095 |
Tyramine
4-hydroxyphenethylamine,酪胺,para-tyramine,p-Tyramine,mydrial,Tocosine,Uteramine |
MAO; Endogenous Metabolite | Metabolism; Neuroscience |
Tyramine (Uteramine) 是天然存在于体内或某些食物中的氨基酸。Tyramine 有助于调节血压。 | |||
T2973 |
Astragaloside IV
AST-IV,黄芪甲苷IV,AS-IV,黄芪皂苷 IV |
MMP; ERK; Estrogen/progestogen Receptor; JNK | Endocrinology/Hormones; MAPK; Proteases/Proteasome |
Astragaloside IV (AS-IV) 是从黄芪中分离得到的一种皂苷,抑制ERK1/2和JNK 激活,在乳腺癌细胞 MDA-MB-231 中,下调(MMP)-2和(MMP)-9的信号通路。 |