keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Neuropeptide Y (NPY) is a 36-amino acid neuropeptide that exerts its activity via G-protein-coupled receptors. NPY is widely distributed in the peripheral and central nervous systems. It modulates a variety of physiological processes, e.g. the central regulation of vasoconstriction, memory retention and food intake, and the regulation of circadian rhythm.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 6,117 | 待询 |
产品描述 | Neuropeptide Y (NPY) is a 36-amino acid neuropeptide that exerts its activity via G-protein-coupled receptors. NPY is widely distributed in the peripheral and central nervous systems. It modulates a variety of physiological processes, e.g. the central regulation of vasoconstriction, memory retention and food intake, and the regulation of circadian rhythm. |
体外活性 | Scrambled NPY peptide treatment had no effect on VEGF expression in 4T1 cells. Previous treatment with scrambled NPY at concentrations ranging from 10?10 to 10?7 M made conditioned media from 4T1 cells show no difference in the number of complete endothelial networks or branch points versus control in endothelial tube formation assays [2][3]. |
体内活性 | In trimethyltin-treated (TMT-treated) rats, treatment with scrambled NPY for 24 h made the expression of Bdnf, NpyR, neurogenic and antiapoptotic genes comparable to that of saline-injected animals (without significant differences). In TMT-treated rats, both saline and scNPY showed no significant modulation (p> 0.05) in the expression levels of Npy1R, Npy2R, and Npy5R [4][5]. |
分子量 | 4253.7 |
分子式 | C190H287N55O57 |
CAS No. | TP2194 |
keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 1 mg/ml
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Neuropeptide Y (scrambled) TP2194 Others Neuropeptide Y scrambled Inhibitor inhibitor inhibit