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Search Results for " lysyl "

58

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T61156	L-Lysyl-L-lysine dihydrochloride Lysyllysine dihydrochloride	Others	Others
	L-Lysyl-L-lysine dihydrochloride (Lysyllysine dihydrochloride) 是一种酶可裂解的接头。L-Lysyl-L-lysine dihydrochloride 可用作递送多种生物活性肽的简单接头。
T33083	Lysyl threonine L-Threonine, l-lysyl-,Dipeptide-7,Dipeptide KT
	Lysyl threonine is a dipeptide composed of lysine and threonine. It is an incomplete breakdown product of protein digestion or protein catabolism.
T33082	Lysyl ornithine monohydrochloride
	Lysyl ornithine monohydrochloride is a bioactive chemical.
T33081	Lysyl ornithine
	Lysyl ornithine is a bioactive chemical.
T33085	Lysyl-alanyl-alanine
	Lysyl-alanyl-alanine is a bioactive chemical.
T33097	Lysyl-serine
	Lysyl-serine is a bioactive chemical.
T21046	Lysyl-tyrosyl-lysine
	Lysyl-tyrosyl-lysine is a bioactive chemical.
T33093	Lysyl-phenylalanyl-lysine
	Lysyl-phenylalanyl-lysine is a bioactive chemical.
T33086	Lysyl-alanyl-beta-naphthylamide
	Lysyl-alanyl-beta-naphthylamide is a bioactive chemical.
T33801	o-Nitrophenylsulfenyl-lysyl-tryptophan
	o-Nitrophenylsulfenyl-lysyl-tryptophan is a bioactive chemical.
T33098	Lysyl-tyrosyl-serine acetate
	Lysyl-tyrosyl-serine acetate is a bioactive chemical.
T32820	L-Lysyl-L-lysinamide
	L-Lysyl-L-lysinamide is a bioactive chemical.
T33084	Lysyl-5-fluorotryptophyl-lysine
	Lysyl-5-fluorotryptophyl-lysine is a bioactive chemical.
T33080	Lysyl aspartyl isoleucine Tripeptide-10,Lys-asp-ile
	Lysyl aspartyl isoleucine（Tripeptide-10）是一种生物活性肽，具有抗皱作用，已被报道用作化妆品成分
T34622	Seryl-lysyl-leucine Skl tripeptide,Ser-lys-leu
	Seryl-lysyl-leucine is a bioactive chemical.
T20462	Lysyllysyllysine Trilysine,Lys-lys-lys,L-Lysine, L-lysyl-L-lysyl-
	Lysyllysyllysine is a cationic moiety. It may be used in the construction of gene delivery vectors and DNA nanoparticles.
T33087	Lysyl-aspartyl-glutamyl-leucine Kdel sequence,Lys-asp-glu-leu
	Lysyl-aspartyl-glutamyl-leucine maintains type II surface membrane proteins in the endoplasmic reticulum.
T33090	Lysyl-histidyl-phenylalanyl-arginyl-tryptophyl-glycinamide
	Lysyl-histidyl-phenylalanyl-arginyl-tryptophyl-glycinamide is an ACTH fragment; cyclic analog evoked excessive grooming behavior in rabbits when administered intracerebroventricularly.
T33829	O-tert-Butyl lysyl-tryptophyl-glycyl-lysinate
	O-tert-Butyl lysyl-tryptophyl-glycyl-lysinate is a bioactive chemical.
T76384	Methionyl-Lysyl-Bradykinin
	Methionyl-Lysyl-Bradykinin (Met-Lys-Bradykinin)，是一种Bradykinin 类似物，是一种激肽。
T33088	Lysylcysteine LYS CYS,LYS-CYS,L-Cysteine, L-lysyl-,LYSCYS
	Lysylcysteine is a dipeptide composed of lysine and cysteine. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived
TP2461	Lpigppal Lysyl-prolyl-isoleucyl-glutamyl-phenylalanyl-4-nitrophenylalanyl-arginyl-leucine
	Lysyl-prolyl-isoleucyl-glutamyl-phenylalanyl-4-nitrophenylalanyl-arginyl-leucine is a bioactive chemical.
T78889	Lysyl hydroxylase 2-IN-1	Monoamine Oxidase	Neuroscience
	Lysyl hydroxylase 2-IN-1 (compound 12) 是高选择性对赖氨酰羟化酶 2 (LH2) 的抑制剂，IC50 值约为 300 nM，相比之下，该化合物对 LH1 和 LH3 的选择性较低。
T78898	Lysyl hydroxylase 2-IN-2	Monoamine Oxidase	Neuroscience
	Lysyl hydroxylase 2-IN-2（compound 13）为一高效Lysyl hydroxylase 2 (LH2)抑制剂，其IC50约为500 nM。该化合物能够抑制344SQ野生型细胞迁移，而对于LH2敲除的344SQ细胞迁移则无影响。
T33096	AT-Cdop Lysyl-prolyl-glycyl-glutamyl-prolyl-glycyl-prolyl-lysine
	Lysyl-prolyl-glycyl-glutamyl-prolyl-glycyl-prolyl-lysine is a bioactive chemical.
T39986	LOX-IN-3 dihydrochloride	Lipoxygenase	Metabolism
	LOX-IN-3 dihydrochloride 是口服有效的赖氨酰氧化酶抑制剂，在纤维化，癌症和/或血管生成方面有研究价值。
T64693	L-Threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-L-proline acetate
	L-Threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-L-proline acetate 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64693。
T38063	N-Acetyl lysyltyrosylcysteine amide	Glutathione Peroxidase	Metabolism
	N-Acetyl lysyltyrosylcysteine amide 是一种无毒的髓过氧化物酶 (MPO) 三肽抑制剂，具有有效性，可逆性和特异性。N-Acetyl lysyltyrosylcysteine amide 在体内可有效抑制 MPO 产生。N-Acetyl lysyltyrosylcysteine amide 减轻中风后大脑的神经元损伤，并保留脑组织和神经功能。N-Acetyl lysyltyrosylcysteine amide 抑制MPO依赖性次氯酸 (HOCl) 的生成，蛋白质硝化和 LDL 氧化。N-Acetyl lysyltyrosylcysteine amide 可用于研究支气管发育不良。
T29485	7-Lysylalanyl-4-methylcoumarinamide
	7-Lysylalanyl-4-methylcoumarinamide is a Fluorogenic substrate for dipeptidyl aminopeptidase.
T32821	L-Lysylpradimicin A
	L-Lysylpradimicin A is a bioactive chemical.
T33091	Lysyllysine Lys-lys,L-Lys-L-lys
	Lysyllysine is a dipeptide composed of two lysine residues. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived in
T33095	Lysylproline
	Lysylproline Third & fourth amino acid in substance P sequence.
T25768	Lysylphenylalanine Lys-phe
	Lysylphenylalanine is a cell sickling and a gelatin inhibitor of hemoglobin S.
T38063L	N-Acetyl lysyltyrosylcysteine amide acetate N-Acetyl lysyltyrosylcysteine amide acetate(1287585-40-3 Free base)	Glutathione Peroxidase	Metabolism
	N-Acetyl lysyltyrosylcysteine amide acetate 是一种有效且特异性的髓过氧化物酶 (MPO) 三肽抑制剂。 N-Acetyl lysyltyrosylcysteine amide acetate 抑制 MPO 依赖性次氯酸的生成、蛋白质硝化和 LDL 氧化反应。 N-Acetyl lysyltyrosylcysteine amide acetate 可减少中风后大脑中的神经元损伤并保护脑组织和神经功能。
T33094	Lysylphosphatidylglycerol
	Lysylphosphatidylglycerol is glycerol with two fatty acids plus a lysine-glycerol-phosphate, a major membrane phospholipid of Staphylococcus and the lysine positive charge repels DEFENSINS.
T33092	Lysyllysyllysine acetate
	Lysyllysyllysine acetate is a bioactive chemical.
T31366	Dehydrolysylnorleucine Dehydro-lys-nle
	Dehydrolysylnorleucine is a bioactive chemical.
T33089	Lysylglutamic acid dihydrate
	Lysylglutamic acid dihydrate is a bioactive chemical.
T12584	PXS-5120A	Others; Monoamine Oxidase	Neuroscience; Others
	PXS-5120A 是一种不可逆的 Lysyl Oxidase-like 2/3 (LOXL2/3) 的氟代烯丙胺抑制剂，具有抗纤维化活性。
T11919	LysRs-IN-1 9-carboxymethylguanine	Others	Others
	LysRs-IN-1是一种赖氨酰-tRNA 合成酶（LysRs）的抑制剂。
T12585	PXS-5153A	Others; Monoamine Oxidase	Neuroscience; Others
	PXS-5153A 是一种有效、特异性和速效的Lysyl Oxidase-like 2/3 (LOXL2/3) 抑制剂，其酶活性在 15 分钟内几乎完全阻断。 PXS-5153A 可以减少交联并改善纤维化。
T20533	NNK Nicotine-derived nitrosamine ketone	Lipoxygenase	Metabolism
	NNK (Nicotine-derived nitrosamine ketone) 是尼古丁亚硝化衍生物。它可以激活 ERK1/2和 PKCα，并在 Ser70 激活 Bcl2磷酸化，以及在 Thr58和 Ser62激活 c-Myc。它可用于构建肺癌小鼠模型，以及诱导人肺癌细胞的增殖和存活。
T17211	Vafidemstat ORY-2001	Histone Demethylase; MAO	Chromatin/Epigenetic; Metabolism; Neuroscience
	Vafidemstat (ORY-2001) 是一种可透过血脑屏障且具有选择性、口服活性的赖氨酸-组蛋白去甲基化酶 (LSD1)/MAO-B 抑制剂，可用于研究神经系统疾病。
T26969	CCT365623 CCT-365623,CCT 365623	Monoamine Oxidase	Neuroscience
	CCT365623 是一种口服生物可利用的赖氨酰氧化酶抑制剂，具有良好的抗 LOX 效力、选择性、药代动力学特性以及抗转移功效。
T69913	Lenumlostat PAT-1251,GB2064	Monoamine Oxidase	Neuroscience
	Lenumlostat 是一种可口服且具有选择性和有效性的赖氨酰氧化酶样蛋白 2 (LOXL2) 抑制剂，对 hLOXL2 、 hLOXL3 和 LOXL2 具有抑制作用，可用于研究纤维性疾病。
T76700	Simtuzumab GS 6624,AB 0024	Monoamine Oxidase	Neuroscience
	Simtuzumab 是一种针对赖氨酰氧化酶样蛋白 2 (LOXL2) 的单克隆抗体。Simtuzumab 可用于治疗原发性硬化性胆管炎 (PSC)，对非酒精性脂肪性肝炎引起的桥接性纤维化或代偿性肝硬化患者无效。
T11920	LysRs-IN-2	Others	Others
	LysRs-IN-2 is a lysyl-tRNA synthetase (KRS) inhibitor with IC50s of 0.13 μM and 0.015 μM for Cryptosporidium parvum lysyl-tRNA synthetase (CpKRS) and Plasmodium falciparum lysyl-tRNA synthetase (PfKRS), respectively.
T38294	4-Deoxypyridoxine hydrochloride	S1P Receptor	GPCR/G Protein
	4-Deoxypyridoxine hydrochloride 通过抑制 S1P 裂解酶 (SPL) 活性来抑制细胞内 S1P 的降解，与 S1P 一样，减少化学诱导的胰岛素瘤细胞系的细胞凋亡。
T12371	PAT-1251 Hydrochloride	Others	Others
	PAT-1251 Hydrochloride is a potent, selective and oral inhibitor of lysyl oxidase-like 2 (LOXL2)(hLOXL2 and hLOXL3 with IC50s of 0.71 and 1.17 μM , respectively),
T10719	CCT365623 hydrochloride	Lipoxygenase	Metabolism
	CCT365623 hydrochloride is an orally active inhibitor of lysyl oxidase (LOX) (IC50: 0.89 μM). It suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF.

化合物

L-Lysyl-L-lysine dihydrochloride

Cat.No: T61156

Synonym: Lysyllysine dihydrochloride

Target: Others

Lysyl threonine

Cat.No: T33083

Synonym: L-Threonine, l-lysyl-,Dipeptide-7,Dipeptide KT

Lysyl ornithine monohydrochloride

Cat.No: T33082

Lysyl ornithine

Cat.No: T33081

Lysyl-alanyl-alanine

Cat.No: T33085

Cat.No: T33097

Lysyl-tyrosyl-lysine

Cat.No: T21046

Lysyl-phenylalanyl-lysine

Cat.No: T33093

Lysyl-alanyl-beta-naphthylamide

Cat.No: T33086

o-Nitrophenylsulfenyl-lysyl-tryptophan

Cat.No: T33801

Lysyl-tyrosyl-serine acetate

Cat.No: T33098

L-Lysyl-L-lysinamide

Cat.No: T32820

Lysyl-5-fluorotryptophyl-lysine

Cat.No: T33084

Lysyl aspartyl isoleucine

Cat.No: T33080

Synonym: Tripeptide-10,Lys-asp-ile

Seryl-lysyl-leucine

Cat.No: T34622

Synonym: Skl tripeptide,Ser-lys-leu

Lysyllysyllysine

Cat.No: T20462

Synonym: Trilysine,Lys-lys-lys,L-Lysine, L-lysyl-L-lysyl-

Lysyl-aspartyl-glutamyl-leucine

Cat.No: T33087

Synonym: Kdel sequence,Lys-asp-glu-leu

Lysyl-histidyl-phenylalanyl-arginyl-tryptophyl-glycinamide

Cat.No: T33090

O-tert-Butyl lysyl-tryptophyl-glycyl-lysinate

Cat.No: T33829

Methionyl-Lysyl-Bradykinin

Cat.No: T76384

Lysylcysteine

Cat.No: T33088

Synonym: LYS CYS,LYS-CYS,L-Cysteine, L-lysyl-,LYSCYS

Cat.No: TP2461

Synonym: Lysyl-prolyl-isoleucyl-glutamyl-phenylalanyl-4-nitrophenylalanyl-arginyl-leucine

Lysyl hydroxylase 2-IN-1

Cat.No: T78889

Target: Monoamine Oxidase

Lysyl hydroxylase 2-IN-2

Cat.No: T78898

Target: Monoamine Oxidase

Cat.No: T33096

Synonym: Lysyl-prolyl-glycyl-glutamyl-prolyl-glycyl-prolyl-lysine

LOX-IN-3 dihydrochloride

Cat.No: T39986

Target: Lipoxygenase

L-Threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-L-proline acetate

Cat.No: T64693

N-Acetyl lysyltyrosylcysteine amide

Cat.No: T38063

Target: Glutathione Peroxidase

7-Lysylalanyl-4-methylcoumarinamide

Cat.No: T29485

L-Lysylpradimicin A

Cat.No: T32821

Cat.No: T33091

Synonym: Lys-lys,L-Lys-L-lys

Cat.No: T33095

Lysylphenylalanine

Cat.No: T25768

Synonym: Lys-phe

N-Acetyl lysyltyrosylcysteine amide acetate

Cat.No: T38063L

Synonym: N-Acetyl lysyltyrosylcysteine amide acetate(1287585-40-3 Free base)

Target: Glutathione Peroxidase

Lysylphosphatidylglycerol

Cat.No: T33094

Lysyllysyllysine acetate

Cat.No: T33092

Dehydrolysylnorleucine

Cat.No: T31366

Synonym: Dehydro-lys-nle

Lysylglutamic acid dihydrate

Cat.No: T33089

Cat.No: T12584

Target: Others, Monoamine Oxidase

Cat.No: T11919

Synonym: 9-carboxymethylguanine

Target: Others

Cat.No: T12585

Target: Others, Monoamine Oxidase

Cat.No: T20533

Synonym: Nicotine-derived nitrosamine ketone

Target: Lipoxygenase

Cat.No: T17211

Synonym: ORY-2001

Target: Histone Demethylase, MAO

Cat.No: T26969

Synonym: CCT-365623,CCT 365623

Target: Monoamine Oxidase

Cat.No: T69913

Synonym: PAT-1251,GB2064

Target: Monoamine Oxidase

Cat.No: T76700

Synonym: GS 6624,AB 0024

Target: Monoamine Oxidase

Cat.No: T11920

Target: Others

4-Deoxypyridoxine hydrochloride

Cat.No: T38294

Target: S1P Receptor

PAT-1251 Hydrochloride

Cat.No: T12371

Target: Others

CCT365623 hydrochloride

Cat.No: T10719

Target: Lipoxygenase

Cat. No.	Product Name	Target	Signaling Pathways
T13475	β-Aminopropionitrile 3-氨基丙腈,3-Aminopropionitrile,BAPN	Others; Endogenous Metabolite	Metabolism; Others
	β-Aminopropionitrile (3-Aminopropionitrile) 是赖氨酰氧化酶的特异性抑制剂。
T20852	Triamcinolone diacetate
	Triamcinolone diacetate is an antagonist of Lysyl oxidase.

天然产物

β-Aminopropionitrile

Cat.No: T13475

Synonym: 3-氨基丙腈,3-Aminopropionitrile,BAPN

Target: Others, Endogenous Metabolite

Triamcinolone diacetate

Cat.No: T20852

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