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Cat. No.	Product Name	Target	Signaling Pathways
T9347	EAAT2 activator 1 3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine	transporter	Metabolism
	EAAT2 activator 1 (3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine) 是兴奋性氨基酸转运蛋白 2(EAAT2) 的有效激活剂，以剂量依赖性方式增加 EAAT2 蛋白水平。
T2556	Nandrolone decanoate 癸酸诺龙,19-Nortestosterone decanoate	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	Nandrolone decanoate (19-Nortestosterone decanoate) 是一种合成代谢雄激素，通过涉及谷氨酸诱导的 N-甲基-D-天冬氨酸受体过度兴奋的机制诱导攻击性行为表征。
T15728	LDN-212320 LDN-0212320,LDN/OSU-0212320,OSU-0212320	transporter	Metabolism
	LDN-212320 (OSU-0212320) 是兴奋性氨基酸转运体 2(EAAT2)/谷氨酸转运体(GLT-1)的激活剂。它通过上调海马和 ACC 星形胶质细胞 GLT-1 的水平来预防伤害性疼痛。
T0313	Evans blue Direct Blue 53,C.I. 23860,伊文思蓝	GluR	Neuroscience
	Evans blue (C.I. 23860) 是一种突触泡谷氨酸吸收的有效抑制剂，同时也是一种AMPA/kainate 受体拮抗剂。
T11451	GPI-1046 1-(1,2-二氧代-3,3-二甲基戊基)-L脯氨酸-(3-吡啶基)-丙酯	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	GPI-1046 是一种无抗生素作用的亲免素配体，部分通过上调 PFC 和 NAc 核心中的谷氨酸转运蛋白 1 来减少乙醇摄入。
T5523	Imidazole ketone erastin IKE	Ferroptosis	Apoptosis
	Imidazole ketone erastin (IKE) 是一种铁死亡诱导剂，对 system Xc-胱氨酸/谷氨酸转运蛋白具有抑制作用。Imidazole ketone erastin 具有抗肿瘤活性，可以诱导谷胱甘肽耗竭和脂质过氧化。
T64357	FA16 FA 16,FA-16	Ferroptosis	Apoptosis
	FA16 是一种选择性、代谢稳定的铁死亡 (ferroptosis) 诱导剂，IC50 值为1.26 μM。FA16 是 2-(三氟甲基) 苯并咪唑的衍生物。FA16 对胱氨酸/谷氨酸反转运蛋白 (system Xc-) 介导了细胞内谷氨酸和细胞外胱氨酸的交换有抑制作用。FA16 在 HepG2 异种移植瘤模型中显著抑制肿瘤生长。
T23454	TFB-TBOA	Others	Others
	glial glutamate transporter EAAT1 and EAAT2 inhibitor
T12099	MPDC	Others	Others
	MPDC acts as a competitive inhibitor against the Na+-dependent high-affinity glutamate transporter within forebrain synaptosomes.
T11055	DL-TBOA	transporter	Metabolism
	DL-TBOA inhibited [14C] glutamate uptake in COS-1 cells expressing human EAAT1 and EAAT2, with Ki values of 42 μM and 5.7 μM, respectively. DL-TBOA blocks EAAT4 and EAAT5 in a competitive manner, with Ki values of 4.4 μM and 3.2 μM, respectively. DL-TBOA
T35994	Erastin2 Erastin2
	Erastin2 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter.[1] [2] It inhibits glutamate release in CCF-STTG1 cells (IC50 = 0.0035 &#181M).[2] It induces cell death in HAP1 cells when used at a concentration of 5 &#181M, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 or deferoxamine . [1] Erastin2 also induces ferroptotic cell death in HT-1080 cells (EC50 = 0.15 &#181M), an effect that can be blocked by the reducing agent β-merc...
T39510	DL-TBOA ammonium
	DL-TBOA ammonium is a potent, non-transportable inhibitor of excitatory amino acid transporters. Its inhibitory effects are demonstrated by IC50 values of 70 μM, 6 μM, and 6 μM for excitatory amino acid transporter-1 (EAAT1), EAAT2, and EAAT3, respectively. Additionally, DL-TBOA ammonium significantly hampers the uptake of [14C]glutamate in COS-1 cell lines expressing human EAAT1 and EAAT2, evident by Ki values of 42 μM and 5.7 μM, respectively. Furthermore, this compound competitively blocks EA...