Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T17842 |
DOTA-NHS-ester
|
Others | Others |
DOTA-NHS-ester 是 affibody 分子的接头,应用于小动物 PET、SPECT 和 CT。 它可用于标记放射治疗剂或成像探针以检测肿瘤。 | |||
T7196 |
HG-10-102-01
[4-[[5-氯-4-(甲基氨基)-2-嘧啶基]氨基]-3-甲氧基苯基]-4-吗啉基甲酮 |
LRRK2 | Autophagy |
HG-10-102-01 是富含亮氨酸重复激酶 2 和突变型G2019S 抑制剂,IC50分别为20.3 nM 和3.2 nM。 | |||
T13151L |
THK5351
|
Others | Others |
THK5351 是一种参与PET成像的示踪剂,参与阿尔茨海默病和认知障碍的电子发射断层扫描成像。 | |||
T18889 |
5-Aminofluorescein
5-氨基荧光素,5-AF |
Others | Others |
5-Aminofluorescein (5-AF) (5-AF) is a covalently-bound fluorescence marker conjugated with human serum albumin. It exhibits an excitation wavelength of 490 nm and an emission wavelength of 515 nm. | |||
T19573 |
T807
AV-1451 |
Microtubule Associated | Cytoskeletal Signaling |
T807 (AV-1451) 是新型的tau 正电子发射断层扫描示踪剂。 | |||
T15025L |
CY5 triethylamine salt
CY5 triethylamine salt(146368-11-8 Free base) |
Others | Others |
CY5 triethylamine salt 是一种水溶性染料,激发光波长(nm):649,发射波长(nm):670。 | |||
T18991 |
Fluorescein-5-maleimide
N-(5-Fluoresceinyl)maleimide,荧光素-5-马来酰亚胺 |
Others | Others |
Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) 是硫醇反应荧光染料 (λex=494 nm,λem=519 nm),可用于将荧光素与蛋白质缀合。 | |||
T9120 |
HBC
Benzeneacetonitrile, 4-cyano-α-[[4-[(2-hydroxyethyl)methylamino]phenyl]methylene]-,HBC 530 |
Others | Others |
HBC (HBC 530) 530 是绿色荧光蛋白 (GFP) 类荧光团的合成染料,具有结构刚性的电子受体和强电子供体。它能够用于 RNA 定位的检测。 | |||
T18891 |
5-TAMRA
5-羧基四甲基罗丹明,5-Carboxytetramethylrhodamine |
Others | Others |
5-TAMRA (5-Carboxytetramethylrhodamine) 能够产生明亮的、pH 不敏感的橙红色荧光 (λex=546 nm,λem=579 nm),有良好的光稳定性。 | |||
TD0106 |
IR-783
|
Others | Others |
IR-783 是一种七次甲基花青荧光探针,用于肿瘤细胞的体内成像。它分别显示 633/780 nm 的激发/发射值。 | |||
T38851 |
SiR-COOH
|
||
SiR-COOH 可用于跟踪 GFP 细胞中治疗药物模型的细胞内位置(Abs,645 nm;Em,676 nm)。 | |||
T18949L |
CY5-SE Ditriethylamine salt
CY5-SE Ditriethylamine salt(146368-14-1 Free base) |
Others | Others |
CY5-SE Ditriethylamine salt 是用于标记寡核苷酸,肽,蛋白质的氨基基团的反应染料。 激发波长 (nm): 649, 发射波长 (nm): 670 | |||
T14054 |
5-TAMRA-SE
5-羧基四甲基罗丹明琥珀酰亚胺酯,5-Carboxytetramethylrhodamine succinimidyl ester,5-TAMRA-NHS ester |
Others | Others |
5-TAMRA-SE 是一种胺反应性荧光剂。它的结合物能够产生一种 pH 不敏感的、明亮的橙红色荧光(Ex/Em~546/579 nm),具有良好的光稳定性。 | |||
T40842 |
ER-Tracker Green
|
||
ER-Tracker Green (ERTG) 是一种细胞通透性活细胞染色剂,用于活细胞成像。ER-Tracker Green 激发波长为 504 nm,发射波长为 511 nm。 | |||
T21343 |
PTZ-343
PTZ-343 sodium,PTZ 343,吩噻嗪-10-基-丙基磺酸钠盐 |
Others | Others |
PTZ-343 是一种鲁米诺的强效发光增强剂 (enhancer)。它极大的增强了过氧化物酶催化的鲁米诺化学发光氧化反应 (>80%) 的光输出。 | |||
T18903 |
6-ROX
6-Carboxy-X-rhodamine,6-羧基-X-罗丹明 |
Others | Others |
6-ROX (6-Carboxy-X-rhodamine) 是寡核苷酸的荧光标记物,其激发波长和发射波长均为568nm。它是耦合至5-FAM 的受体,在FRET 成像中作为供体。 | |||
T39817 |
Msr-Ratio
Msr-green,Msr-Ratio |
Others | Others |
Msr-Ratio (Msr-green) (Msr-green) is a ratiometric fluorescent probe specifically designed for the detection of methionine sulfoxide reductase (MSR) activity. It has an excitation wavelength of 375 nm and an emission wavelength of 550 nm. This probe offers the ability to monitor the enzyme activity both in vitro and in live cells, making it a valuable tool for studying MSR function. | |||
T26360 |
Benperidol
R4584,R-4584,Anquil,McN-JR-4584,R 4584 |
||
Benperidol (Anquil)是一种具有抗精神病和安定作用的丁酮类化合物,在阻断 D2 受体方面具有很好的疗效。Benperidol可用于正电子发射断层扫描(PET)测量体内 D(2)类多巴胺受体的结合情况。 | |||
T36343 |
Ac-LETD-AFC
|
||
Ac-LETD-AFC 是一种可被 caspase-8 特异性裂解的荧光底物,可通过荧光检测游离 AFC来量化 Caspase 活性。Ac-LETD-AFC 激发波长为 400 纳米,发射波长为 505 纳米。 | |||
T36587 |
8-Aminopyrene-1,3,6-trisulfonic Acid sodium salt
|
Others | Others |
8-Aminopyrene-1,3,6-trisulfonic Acid sodium salt 是一种阴离子荧光染料,用作葡萄糖传感和检测其他糖类的报告分子。激发/发射光谱为 425/503 nm。 它可以在溶液中使用,也可以通过还原胺化连接醛官能化单体来固定,而不会显著改变荧光强度。 | |||
T1699 |
resorufin galactopyranoside
|
Others | Others |
resorufin galactopyranoside 是β-半乳糖苷酶的荧光底物,在被β-半乳糖苷酶酶切后,荧光部分间苯二酚被释放,其荧光可用于定量β-半乳糖糖苷酶的活性。它的激发光为570,发射光为580nm。 | |||
T6802 |
CFSE
5(6)-CFDA N-succinmidyl ester,Carboxyfluorescein succinimidyl ester,CFDA-SE,5(6)-羧基二乙酸荧光素琥珀酰亚胺酯,5(6)-Carboxyfluorescein diacetate succinimidyl ester |
Others | Others |
CFSE (CFDA-SE) 属于荧光染料,具有细胞膜渗透性。CFSE 可在活细胞内与胞内蛋白进行不可逆的结合,用于检测细胞增殖,标记的细胞呈绿色荧光,激发波长为 488 nm,发射波长为 518 nm。 | |||
T15082 |
DDAO
|
Others | Others |
DDAO 是有潜在用途的近红外红色荧光探针,其激发波长 (600-650 nm) 和长发射波长 (λem = 656 nm)可以调节。它可用于不同酶活性的检测,如 β-半乳糖苷酶,羧酸酯酶 2,硫酸酯酶,蛋白质磷酸酶 2A,人白蛋白和酯酶。 | |||
T36352 |
Suc-Leu-Tyr-AMC
|
||
Suc-Leu-Tyr-AMC 是钙蛋白酶 I 和 II 以及木瓜蛋白酶(另一种半胱氨酸蛋白酶)的荧光底物,用于测量 20S 蛋白酶体的糜蛋白酶样肽酶活性(Ex-max:360 nm;Em-max:460 nm)。Suc-Leu-Tyr-AMC 也能被大肠杆菌的 Ti 蛋白酶裂解。 | |||
T15162 |
DPA-714
|
Others | Others |
DPA-714 是高亲和力的移位蛋白配体 (Ki=7 nM),它结构中有一个氟原子,能够被氟 -18 进行标记,并可通过正电子发射断层成像进行活体成像。它可在各种神经炎症模型及脑肿瘤模型中成功评估炎症的特异性成像。 | |||
T28466 |
PSMA-11
HBED-CC-PSMA,Psma-hbed-CC,PSMA11 |
||
PSMA-11 (HBED-CC-PSMA)通过与前列腺特异性膜抗原(PSMA)的细胞外结构域结合来检测前列腺癌的复发和转移。PSMA-11常被用作正电子发射断层扫描(PET)中用作表达PSMA 的肿瘤的示踪剂,通过静脉注射镓Ga 68标记的PSMA-11,Glu-urea-Lys(Ahx)分子靶向并结合表达PSMA 的肿瘤细胞。内化后,PSMA 表达的肿瘤细胞可在PET 成像中被检测到。 | |||
T22781L |
FFN 511 hydrochloride
FFN 511 hydrochloride(1004548-96-2 Free base) |
||
FFN 511 hydrochloride 是一种针对神经元囊泡单胺转运体 2 (VMA T2) 的荧光假神经递质 (FFNs)。FFN 511 hydrochloride 可抑制 5-羟色胺与含 VMA T2 的膜结合,可用于标记活体皮质-纹状体急性切片中的多巴胺能神经末梢。激发和发射最大值分别为 406 和 501 nm。 | |||
T19062 |
Sulforhodamine 101
磺基罗丹明101,磺基罗丹明 101,SR101 |
Others | Others |
Sulforhodamine 101 (SR101) 是一种两性罗丹明红色荧光染料 (excitation/emission: 586/605 nm),常用于神经元形态的研究,并作为星形胶质细胞的细胞类型选择性荧光标记物,在体内和切片制备中都有应用。 | |||
T78389 |
Coelenteramine 400a
Bisdeoxycoelenterazine,Coelenterazine 400a |
||
Coelenterazine 400a(Coelenterazine 400a),作为Coelenterazine的一个衍生物,它是海肾荧光素酶(RLuc)的底物。该化合物与RLuc结合后能够在395 nm发射蓝光。Coelenterazine 400a改变了亚甲基桥的硫和氧原子,导致RLuc的生物发光产生色变。它在提供更高的信号分辨率方面具有重要价值,适用于生物发光共振能量转移(BRET)的研究。 | |||
T41194 |
FFN 102 mesylate
|
Others | Others |
FFN 102 mesylate 是pH 响应型荧光假神经递质(FFN),作为选择性多巴胺转运蛋白(DAT)和VMAT2底物。FFN 102 mesylate 与38个中枢神经系统受体(包括多巴胺和血清素受体)无明显结合。它的Ex-max在pH 值5时为340 nm,在pH 值7.5时为370 nm,在pH 值为5和7.5时,Em-max为435 nm。 | |||
T35070 |
Volicitin
(17S)-Volicitin |
||
Volicitin can trigger the emission of volatile from plants. | |||
T20771 |
Lissamine rhodamine B
|
||
Lissamine rhodamine B, a new Radiotracer, is used for Imaging Tumors by Positron Emission Tomography. | |||
T34626 |
Setoperone
R-52245,R 52245,R52245 |
||
Setoperone, as a sensitive radioligand, can be commonly used in position emission tomography (PET) imaging. | |||
T37656 |
MIT-PZR
|
||
MIT-PZR is a mitochondria-targeted fluorescent probe.1It is aggregation-induced emission (AIE) active and displays absorption/emission maxima of 485/705 nm, respectively. MIT-PZR can be used in live cells andin vivo. 1.Dong, Y., Chen, Z., Hou, L., et al.Mitochondria-targeted aggregation-induced emission active near infrared fluorescent probe for real-time imagingSpectrochim. Acta. A. Mol. Biomol. Spectrosc.224117456(2019) | |||
T40322 |
BG dimer
|
||
BG dimer is a molecular dimer organic luminogen with aggregation-induced emission. | |||
T34922 |
TRFS-red
TRFSred |
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TRFS-red is the first red emission off-on probe for thioredoxin reductase. | |||
T31145 |
CycLuc3
Cyc Luc 3,Cyc-Luc-3 |
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CycLuc3 is a type of mutant firefly luciferase variant with enhanced light emission. | |||
T27494 |
GSK931145
GSK 931145,GSK-931145 |
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GSK931145 is a positron emission tomography (PET) radioligand, it is suitable for quantifying glycine transporter (GlyT1) availability in the living brain. | |||
TP1013 |
N-CBZ-Phe-Arg-AMC
Z-FR-AMC |
||
N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a substrate for serine proteases, including cathepsins, kallikrein and plasmin. Absorption/emission of substrate = 330/390 nm (weak fluorescence); absorption/emission of end product (AMC) = 342/441 nm (strong fluorescence). | |||
T24406 |
L-FMAC F-18
L-(18F)-FMAC |
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L-FMAC F-18 has potential diagnostic activity during positron emission tomography (PET) imaging. After phosphorylation by DCK, the 18F moiety can be visualized by PET imaging. | |||
T39069 |
UCB-J
|
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UCB-J is a radioligand for the synaptic vesicle protein 2A (SV2A), utilized in positron emission tomography (PET)[4]. | |||
T30444 |
Bicisate dihydrochloride
Bicisate HCl |
||
Bicisate dihydrochloride is usually complex with technetium Tc99m to measure cerebral blood flow with single-photon emission computed tomography (SPECT). | |||
T33493 |
Mppf F-18
J1.050.795B,P-18FMPPF,(18F) Mppf,(18F)Mppf,(18F)-Mppf |
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Mppf F-18, which has been used as a radioactive ligand for positron emission tomography, is a compound that binds to the serotonin-1A receptor. | |||
T37049 |
monoMICAAc
|
||
monoMICAAc is a solvatochromic fluorescent pH probe.1 As the polarity of the solvent increases, the emission wavelength of monoMICAAc increases. It displays excitation/emission maxima of 425/491, 437/515, and 472/554 nm in hexane, dioxane, and water, respectively. The absorption maximum of monoMICAAc decreases with increasing pH. It displays absorbance/emission maxima of 475/553 and 446/553 nm at pH 3 and 11, respectively, in aqueous Britton-Robinson buffer, and the fluorescence intensity increa... | |||
T36843 |
ICAAc
|
||
ICAAc is a solvatochromic fluorescent pH probe.1 As the polarity of the solvent increases, the emission wavelength of ICAAc increases. It displays excitation/emission maxima of 466/553, 431/515, and 418/503 nm in water, dioxane, and hexane, respectively. The absorption maximum of ICAAc decreases with increasing pH. It displays absorption/emission maxima of 470/554 and 428/553 nm at pH 3 and 11, respectively, in aqueous Britton-Robinson buffer, and the fluorescence intensity increases as pH decre... | |||
T36948 |
NIAD-4
|
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NIAD-4 is a fluorescent probe that crosses the blood-brain barrier to bind with high affinity to amyloid-β (Aβ) plaques (Ki = 10 nM). It displays excitation/emission spectra of 475/625 nm, respectively, with the far-red emission occurring upon binding to Aβ. | |||
T39759 |
Janelia Fluor® 549 TFA
JF549 TFA |
||
Janelia Fluor 549 TFA (JF549 TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm. | |||
T19039 |
NIR-Thiol dinitrobenzenesulfonate
|
Others | Others |
NIR-Thiol dinitrobenzenesulfonate has both absorption and emission in the NIR region. It is capable of imaging endogenously produced thiol in living cells and mice. | |||
T24956 |
(18F)LBT 999
(18F)LBT999,LBT999 18F,LBT 999 18F,LBT-999 18F,(18F)LBT-999 |
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(18F)LBT 999 is a positron emission tomography (PET) tracer, used for the quantification of the dopamine transporter (DAT) in the healthy rat brain. | |||
T39240 |
Janelia Fluor® 549, SE
JF549, SE,JF549,NHS |
||
Janelia Fluor 549, SE (JF549, SE) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm. |