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Cat. No. Product Name Target Signaling Pathways
T8372 VU0134992

VU 0134992

Potassium Channel Membrane transporter/Ion channel
VU 0134992 是一个亚型偏好的,口服有效的和选择性的内向整流钾通道 Kir4.1阻滞剂,IC50为 0.97 μM。在 -120 mV 时,VU0134992对同分 Kir4.1 比 Kir4.1/5.1 共分通道 (IC50=9 μM) 高出 9 倍的选择性。
T13316 VU0134992 hydrochloride

Potassium Channel Membrane transporter/Ion channel
VU0134992 hydrochloride 是一个亚型偏好的,具有口服活性和选择性的内向整流钾通道Kir4.1阻滞剂,IC50为 0.97 μM。在 -120 mV 时,VU0134992 hydrochloride 对同分 Kir4.1 比 Kir4.1/5.1 共分通道 (IC50=9 μM) 高出 9 倍的选择性。
T1484L Perindopril erbumine

培哚普利叔丁胺,培哚普利叔丁胺盐,S9490-3,Perindopril tert-butylamine salt

Apoptosis; RAAS; MRP Apoptosis; Endocrinology/Hormones; Immunology/Inflammation
Perindopril erbumine (S9490-3) 是一种长效血管紧张素转换酶抑制剂。
T1083L Theophylline monohydrate

Quibron,茶碱一水合物

HDAC; PDE; Adenosine Receptor Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
Theophylline monohydrate (Quibron) 似乎抑制磷酸二酯酶和前列腺素的产生,调节钙通量和细胞内钙分布,并拮抗腺苷。茶碱是黄嘌呤的天然生物碱衍生物,从植物山茶花和小粒咖啡中分离出来。在生理上,该药剂可放松支气管平滑肌,产生血管舒张(脑血管除外),刺激中枢神经系统,刺激心肌,利尿,增加胃酸分泌;它还可以抑制炎症并改善横膈膜的收缩性。
T1400L Demeclocycline

Ledermycin,Bioterciclin,Deteclo,Declostatin,Deganol

Antibacterial Microbiology/Virology
Demeclocycline (Declostatin) 是一种四环素类抗生素,产自金霉素链霉菌(Streptomyces aureofaciens)菌株。Demeclocycline 具有抗菌活性,能抑制血管加压素对肾小管的作用,从而导致利尿。Demeclocycline 可用诱导尿崩症和急性肾衰竭。
T70939 8-Aminoinosine

8-Aminoinosine is an endogenous 8-aminopurine that induces diuresis, natriuresis, and glucosuria by inhibiting purine nucleoside phosphorylase (PNPase).
T28313 PD 117302

PD-117302,PD117302

PD 117302 is a nonpeptide opioid compound. It is a selective kappa-opioid agonist. PD 117302 causes naloxone-reversible locomotor impairment and diuresis. It is an Anti-Arrhythmia Agent, an Anticonvulsants, a Cardiovascular Agent, and a Central Nervous Sy
T73218 Epitizide

Epitizide 是一种苯并噻二嗪,常与Triamterene 联合使用,产生利尿作用。
T75894 Sauvagine TFA

Sauvagine TFA,是一种来自青蛙皮肤的 40 个氨基酸的神经肽,是哺乳动物 CRF 激动剂。Sauvagine TFA 可有效从大鼠垂体细胞释放 ACTH。Sauvagine TFA 在利尿,心血管系统和内分泌腺体方面具有许多药理作用。
T70250 Demeclocycline calcium

Demeclocycline calcium is a semisynthetic tetracycline antibiotic which was derived from a strain of Streptomyces aureofaciens. Demeclocycline binds to bacterial 30S ribosomal subunit and prevents binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. Demeclocycline also inhibits the effect of vasopressin on the renal tubules, thereby causing diuresis.
TP1209 BNP (1-32), rat TFA (133448-20-1 free base)

Brain Natriuretic Peptide (BNP) (1-32), rat TFA,BNP (1-32), rat TFA

Acts as a cardiac hormone with a variety of biological actions including natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. It is thought to play a key role in cardiovascular homeostasis. Helps restore the body\'s sa
T70097 Acefylline piperazine

Acefylline piperazine is a stimulant drug of the xanthine chemical class. It acts as an adenosine receptor antagonist. Acephylline piperazine is a theophylline derivative with a direct bronchodilator action. It has the advantages over theophylline in being far less toxic and producing minimal gastric irritation. It is indicated for the treatment of asthma, emphysema, acute and chronic bronchitis associated with bronchospasm.Acefylline relaxes smooth muscles, relieves bronchospasm & has a stimula...

化合物

VU0134992
Cat.No: T8372
Synonym: VU 0134992
Target: Potassium Channel
VU0134992 hydrochloride
Cat.No: T13316
Synonym:
Target: Potassium Channel
Perindopril erbumine
Cat.No: T1484L
Synonym: 培哚普利叔丁胺,培哚普利叔丁胺盐,S9490-3,Perindopril tert-butylamine salt
Target: Apoptosis, RAAS, MRP
Theophylline monohydrate
Cat.No: T1083L
Synonym: Quibron,茶碱一水合物
Target: HDAC, PDE, Adenosine Receptor
Demeclocycline
Cat.No: T1400L
Synonym: Ledermycin,Bioterciclin,Deteclo,Declostatin,Deganol
Target: Antibacterial
8-Aminoinosine
Cat.No: T70939
Synonym:
Target:
PD 117302
Cat.No: T28313
Synonym: PD-117302,PD117302
Target:
Epitizide
Cat.No: T73218
Synonym:
Target:
Sauvagine TFA
Cat.No: T75894
Synonym:
Target:
Demeclocycline calcium
Cat.No: T70250
Synonym:
Target:
BNP (1-32), rat TFA (133448-20-1 free base)
Cat.No: TP1209
Synonym: Brain Natriuretic Peptide (BNP) (1-32), rat TFA,BNP (1-32), rat TFA
Target:
Acefylline piperazine
Cat.No: T70097
Synonym:
Target:
TargetMol Loading
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