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Search Results for " cystine "

28

抑制剂 & 化合物

8

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T16240	N,N'-Diacetyl-L-cystine (Ac-Cys-OH)2,DiNAC	Others	Others
	N,N'-Diacetyl-L-cystine (DiNAC) 是一种具有免疫调节特性的 N-乙酰基半胱氨酸的二硫二聚体。它在高脂血症兔中也具有抗动脉粥样硬化的作用。它是啮齿类动物中接触敏感/迟发型超敏反应的有效口服活性调节剂。
T31512	Dipalmitoyl cystine Palmitoyl cystine
	Dipalmitoyl cystine is a bioactive chemical.
T40433	D-Cystine
	D-Cystine, the D-enantiomer of L-Cystine, functions as an inhibitor of L-aspartate-β-semialdehyde dehydrogenase (ASADH) derived from Escherichia coli.
T31412	Di(dansyl)cystine Didansylcystine
	Di(dansyl)cystine is a fluorescent label for tropomyosin.
T32615	L-Cystine S,S-dioxide Cystinedisulfoxide
	L-Cystine S,S-dioxide is a metabolite of L-Cystine.
T66846	DL-Cystine
	DL-Cystine 是一种氨基酸衍生物，在生命科学相关研究中具有广泛的应用。
T124989	L-Cystine, hydrochloride
	L-Cystine, hydrochloride 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124989，CAS号为 34760-60-6。
T65273	L-Cystine, disodium salt
	L-Cystine, disodium salt 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65273，CAS号为 64704-23-0。
T8483	Cysteine thiol probe Methyl (4-bromobenzoyl)-L-cysteinate	Others	Others
	Cysteine thiol probe (Methyl (4-bromobenzoyl)-L-cysteinate) 是基于硫醇的探针，旨在标记亲电子的天然产物。它能够结合基于烯酮，β-内酰胺和 β-内酯的亲电子代谢物。它具有理想药效团探针的每个特征，并具有发色团。
T34603	L-Selenocystine L-Selenocystine,L-硒代胱胺基乙酸	Others	Others
	L-Selenocystine (L-Selenocystine) 可用作生物活性硒醇化合物的组成部分。
T34849	Thiocystine
	Thiocystine can be produced in the hydrolysis of proteins.
T24538	N-Monoacetylcystine Parvolex,N-Acetylcystine
	N-Monoacetylcystine is a paracetamol poisoning antidote. It is used in the treatment of influenza A virus pandemic.
T78581	Selenocystine	Others	Others
	Selenocystine为一种广谱抗癌剂，能诱导HepG2细胞发生DNA损伤，尤其是 DNA 双链断裂(DSBs)。Selenocystine在靶向DNA修复领域，作为癌症治疗的潜在治疗或辅助剂，展现出显著的应用前景。
T32101	Homothiocystine
	Homothiocystine has appreciable activity as a substrate.
T5523	Imidazole ketone erastin IKE	Ferroptosis	Apoptosis
	Imidazole ketone erastin (IKE) 是一种铁死亡诱导剂，对 system Xc-胱氨酸/谷氨酸转运蛋白具有抑制作用。Imidazole ketone erastin 具有抗肿瘤活性，可以诱导谷胱甘肽耗竭和脂质过氧化。
T64357	FA16 FA 16,FA-16	Ferroptosis	Apoptosis
	FA16 是一种选择性、代谢稳定的铁死亡 (ferroptosis) 诱导剂，IC50 值为1.26 μM。FA16 是 2-(三氟甲基) 苯并咪唑的衍生物。FA16 对胱氨酸/谷氨酸反转运蛋白 (system Xc-) 介导了细胞内谷氨酸和细胞外胱氨酸的交换有抑制作用。FA16 在 HepG2 异种移植瘤模型中显著抑制肿瘤生长。
T0983L	DL-Penicillamine 3-Sulfanylvaline,DL-青霉胺	Antibiotic	Microbiology/Virology
	DL-Penicillamine (3-Sulfanylvaline) 是一种螯合剂，推荐用于去除威尔逊病患者体内多余的铜。它仅存在于使用或服用该药物的个体中。它是青霉素类抗生素最具特征的降解产物。它被用作抗风湿药和威尔逊病的螯合剂。
T24387	Lanthionine NSC-83248,L-Lanthionine,NSC83248,NSC 83248
	Lanthionine is a thioether analog of cystine.
T30948	Cistinexine
	Cistinexine is an expectorant and mucolytic from cystine.
T31158	Cysteine thiosulfonate Alanine sulfodisulfane
	Cysteine thiosulfonate plays a role in cystine metabolism.
T70374	LH-708
	LH-708 is an inhibitor of cystine stone formation for treatment of cystinuria.
T20118	L-Penicillamine
	L-Penicillamine is a medication primarily. It is used for the treatment of Wilson's disease. It is also used for people with kidney stones who have high urine cystine levels, rheumatoid arthritis, copper poisoning, and lead poisoning.
T80439	GTx1-15	Sodium Channel	Membrane transporter/Ion channel
	GTx1-15为一种抑制剂胱氨酸结 (ICK) 肽，能有效抑制电压依赖性钙通道 Cav3.1 以及电压依赖性钠通道 Nav1.3 和 Nav1.7。
T80189	Hainantoxin-IV HNTX-IV	Sodium Channel	Membrane transporter/Ion channel
	Hainantoxin-IV是针对河豚毒素敏感(TTX-S)电压门控钠通道的特异性拮抗剂。该化合物以His28和Lys32为主要残基与靶标结合，并采用了抑制剂胱氨酸结基序。
T35383	Cysteamine bitartrate Mercaptamine bitartrate	Others	Others
	Cysteamine bitartrate (Mercaptamine bitartrate)是FDA 批准的胱氨酸消耗氨基硫醇药物(cystine-depleting aminothiol agent)，通过参与二硫交换减少溶酶体胱氨酸的积累，用于治疗肾病性胱氨酸病。此外，Cysteamine bitartrate 还具有抗氧化特性。
T35994	Erastin2 Erastin2
	Erastin2 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter.[1] [2] It inhibits glutamate release in CCF-STTG1 cells (IC50 = 0.0035 &#181M).[2] It induces cell death in HAP1 cells when used at a concentration of 5 &#181M, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 or deferoxamine . [1] Erastin2 also induces ferroptotic cell death in HT-1080 cells (EC50 = 0.15 &#181M), an effect that can be blocked by the reducing agent β-merc...
T80169	ProTx-III μ-TRTX-Tp1a	Sodium Channel	Membrane transporter/Ion channel
	ProTx-III是一种从秘鲁绿绒狼蛛毒液中分离得到的蜘蛛毒肽，它是一个选择性且有效的Nav1.7电压门控钠离子通道抑制剂，其IC50值为2.1 nM。ProTx-III特征为含有典型的抑制剂胱氨酸结基序(ICK)，并可逆转疼痛反应，适用于慢性疼痛、癫痫和心律失常等疾病的研究。
T75595	Loxosceles Bergeri Venom
	Loxosceles Bergeri Venom 是一种可以从Loxosceles Bergeri 中获得的毒液。Loxosceles 蜘蛛的毒液是一种复杂的毒素混合物，富含蛋白质、糖蛋白和低分子质量多肽。目前已鉴定出几种蛋白类，包括类虾蛋白酶金属蛋白酶、低分子杀虫肽、抑制剂半胱氨酸结肽 (ICK) 和磷脂酶 D。其中独特的酶，鞘磷脂酶 D 负责坏死的发展。

化合物

N,N'-Diacetyl-L-cystine

Cat.No: T16240

Synonym: (Ac-Cys-OH)2,DiNAC

Target: Others

Dipalmitoyl cystine

Cat.No: T31512

Synonym: Palmitoyl cystine

Cat.No: T40433

Di(dansyl)cystine

Cat.No: T31412

Synonym: Didansylcystine

L-Cystine S,S-dioxide

Cat.No: T32615

Synonym: Cystinedisulfoxide

Cat.No: T66846

L-Cystine, hydrochloride

Cat.No: T124989

L-Cystine, disodium salt

Cat.No: T65273

Cysteine thiol probe

Cat.No: T8483

Synonym: Methyl (4-bromobenzoyl)-L-cysteinate

Target: Others

L-Selenocystine

Cat.No: T34603

Synonym: L-Selenocystine,L-硒代胱胺基乙酸

Target: Others

Cat.No: T34849

N-Monoacetylcystine

Cat.No: T24538

Synonym: Parvolex,N-Acetylcystine

Cat.No: T78581

Target: Others

Homothiocystine

Cat.No: T32101

Imidazole ketone erastin

Cat.No: T5523

Synonym: IKE

Target: Ferroptosis

Cat.No: T64357

Synonym: FA 16,FA-16

Target: Ferroptosis

DL-Penicillamine

Cat.No: T0983L

Synonym: 3-Sulfanylvaline,DL-青霉胺

Target: Antibiotic

Cat.No: T24387

Synonym: NSC-83248,L-Lanthionine,NSC83248,NSC 83248

Cat.No: T30948

Cysteine thiosulfonate

Cat.No: T31158

Synonym: Alanine sulfodisulfane

Cat.No: T70374

L-Penicillamine

Cat.No: T20118

Cat.No: T80439

Target: Sodium Channel

Cat.No: T80189

Synonym: HNTX-IV

Target: Sodium Channel

Cysteamine bitartrate

Cat.No: T35383

Synonym: Mercaptamine bitartrate

Target: Others

Cat.No: T35994

Synonym: Erastin2

Cat.No: T80169

Synonym: μ-TRTX-Tp1a

Target: Sodium Channel

Loxosceles Bergeri Venom

Cat.No: T75595

Cat. No.	Product Name	Target	Signaling Pathways
T2O2733	L-Cystine Cystine Acid,cystine,胱氨酸,L-胱氨酸	Antioxidant; Ferroptosis; Endogenous Metabolite	Apoptosis; Metabolism; oxidation-reduction
	L-Cystine (Cystine Acid) 是一种从半胱氨酸氨基酸硫醇侧链氧化获得的含硫衍生物。它起到抗氧化剂的作用，保护组织免受辐射和污染，减缓衰老过程。它还有助于蛋白质合成。
T60789	L-Cystine dihydrochloride
	L-Cystine dihydrochloride 是合成谷胱甘肽 (GSH) 的含硫前体。L-Cystine dihydrochloride 的稳态对谷胱甘肽的功能很重要。L-Cystine dihydrochloride 可用作细胞培养组分。
T4877	L-Homocystine	Endogenous Metabolite	Metabolism
	L-Homocystine 是一种 L-homocysteine 的氧化物。其中 L-homocysteine 是抗血栓因子、血管舒张损害剂、促炎因子，也是研究心血管疾病发生机制的内质网应激反应的诱导剂。
T66672	DL-Homocystine
	DL-Homocystine 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 T66672，CAS号为 870-93-9。
T16942	Sterigmatocystine	Others	Others
	Sterigmatocystine is an inhibitor of G1 Phase and DNA synthesis and is used to inhibit p21 activity. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor.
T1630	Tiopronin Thiopronine,硫普罗宁,Acadione,Captimer	ROS	Immunology/Inflammation
	Tiopronin (Acadione) 是可扩散的抗氧化剂，是重金属中毒的解毒剂和辐射防护剂。它可控制胱氨酸沉淀和排泄的速度，有用于胱氨酸尿症、类风湿性关节炎和肝病的研究潜力。
T60237	L-Cysteine S-sulfate S-Sulfo-L-cysteine	NMDAR	Neuroscience
	L-Cysteine S-sulfate (S-Sulfo-L-cysteine) 是有效的 N-methyl-d-aspartate (NMDA) 谷氨酸受体激动剂。L-Cysteine S-sulfate 是胱氨酸裂解酶的底物。
T1080	2-Aminoethanethiol 2-Mercaptoethylamine,巯基乙胺,β-Mercaptoethylamine,β-MEA,Cysteamine	Apoptosis; Others; Reactive Oxygen Species; Cysteine Protease; Somatostatin; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Metabolism; NF-κB; Others; Proteases/Proteasome
	2-Aminoethanethiol (Cysteamine) 是一种胱氨酸消耗剂。半胱胺的作用机制是胱氨酸二硫化物还原。

天然产物

Cat.No: T2O2733

Synonym: Cystine Acid,cystine,胱氨酸,L-胱氨酸

Target: Antioxidant, Ferroptosis, Endogenous Metabolite

L-Cystine dihydrochloride

Cat.No: T60789

Cat.No: T4877

Target: Endogenous Metabolite

Cat.No: T66672

Sterigmatocystine

Cat.No: T16942

Target: Others

Cat.No: T1630

Synonym: Thiopronine,硫普罗宁,Acadione,Captimer

Target: ROS

L-Cysteine S-sulfate

Cat.No: T60237

Synonym: S-Sulfo-L-cysteine

Target: NMDAR

2-Aminoethanethiol

Cat.No: T1080

Synonym: 2-Mercaptoethylamine,巯基乙胺,β-Mercaptoethylamine,β-MEA,Cysteamine

Target: Apoptosis, Others, Reactive Oxygen Species, Cysteine Protease, Somatostatin, Endogenous Metabolite, Autophagy

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