首页工具

登录

搜索结果

Search Results for " bisphosphonate "

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T12452	Digeranyl bisphosphonate DGBP	Rho; Ras	Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
	Digeranyl bisphosphonate (DGBP) 是一种有效的香叶基焦磷酸香叶酯 (GGPP) 合酶抑制剂，对 Rac1 的香叶基焦磷酸化有抑制作用。Digeranyl bisphosphonate 诱导细胞发生自噬却不诱导细胞凋亡。
T69443	Aminobutane bisphosphonate
	Aminobutane bisphosphonate is a powerful inhibitor of bone resorption. It can potentially be a useful measure for controlling hypercalcemia in patients with carcinoma.
T6739	Zoledronic Acid CGP-4244,CGP42446A,唑来膦酸,Zoledronate,CGP 42446,ZOL 446,Zometa	Apoptosis; Rho; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint
	Zoledronic Acid (ZOL 446) 是一种含氮二磷酸盐，能抑制破骨细胞的分化和凋亡，具有高效的抗骨质再吸收活性，也有抗癌作用。
T21299	Zoledronic acid monohydrate 唑来膦酸一水合物,zoledronate,ZOL 446,CGP 42446,CGP42446A,Zoledronic acid hydrate	Apoptosis; Others; Autophagy	Apoptosis; Autophagy; Others
	Zoledronic acid monohydrate (CGP 42446) 是一种含氮二磷酸盐，具有高效的抗骨质再吸收活性。它能抑制破骨细胞的分化和凋亡，有抗癌作用。
T1599	Ibandronic acid Bonviva,Bondronat,Boniva,伊班膦酸	Others; HBV	Microbiology/Virology; Others
	Ibandronic acid (Bonviva) 是一种高效含氮双磷酸盐，可作用于骨质疏松，具有抗吸收和抗高钙血症作用。
T1337	Pamidronate Disodium 帕米膦酸钠,CGP 23339A,CGP 23339AE,Pamidronate disodium salt	Others; HBV	Microbiology/Virology; Others
	Pamidronate Disodium (CGP 23339A) 是一种具有强化骨骼作用的物质。
T73506	TH-Z93 THZ93	Antibacterial	Microbiology/Virology
	TH-Z93 是一种有效的 FPPS 抑制剂 (IC50: 90 nM)，也是一种亲脂性双膦酸盐。
T1599L	Ibandronate sodium 伊班膦酸钠,Boniva,Ibandronate sodium salt,Bondronat	HBV; Transferase	Metabolism; Microbiology/Virology
	Ibandronate sodium (Boniva) 是一种高活性的含氮二磷酸盐，可用于骨质疏松的研究。
T6539	Ibandronate sodium monohydrate Boniva monohydrate,Bondronat monohydrate,Ibandronate sodium,伊班膦酸钠单水合物,BM-210955,BM-21.0955,伊班膦酸钠一水合物,RPR-102289A	Apoptosis; Others	Apoptosis; Others
	Ibandronate sodium monohydrate (BM-210955) 是一种高活性的含氮二磷酸盐，可用于骨质疏松。
T6373	Alendronate sodium hydrate G-704650,Alendronate,MK 217,Alendronate sodium trihydrate,阿仑膦酸钠,G-704650 Adronat,Fosamax	Transferase	Metabolism
	Alendronate sodium hydrate (MK 217) 是 farnesyl diphosphate synthase 抑制剂(IC50:460 nM)。
T6451	Clodronic acid disodium salt Loron,Clodronate Disodium,氯屈膦酸二钠,Lodronate	Others	Others
	Clodronic acid disodium salt (Lodronate) 是一种口服具有活力的破骨细胞骨吸收 (osteoclastic bone resorption) 的抑制剂，是一代双磷酸盐。它可用于高骨转换状态、Paget’s 病和溶骨性骨转移中。
T16289	NE 10790 3-PEHPC	Others	Others
	NE 10790 (3-PEHPC) 是一种二磷酸利塞磷酸盐的磷酸酯类似物，是一种法尼焦磷酸合成酶的弱抑制剂，也是一种弱抗吸收剂。
T19415	Medronic acid 亚甲基二磷酸,Methylenediphosphonic acid	Others	Others
	Medronic acid (Methylenediphosphonic acid) 是一种亚甲基取代的二膦酸盐。它对骨基质中的羟基磷灰石晶体的表面具有亲和力，并且可粘附在其表面。它能够在类骨质矿化的位点累积，可以在骨成像中与放射性同位素复合使用。
T14766	BPH-715	Others; Parasite	Microbiology/Virology; Others
	BPH-715 抑制恶性疟原虫的肝脏阶段生长，对 HepG2 细胞中的恶性疟原虫外红细胞的形成的 IC50 为 10 μM。
T10586L	BPH-1358 NSC50460	Others; Antibacterial	Microbiology/Virology; Others
	BPH-1358 (NSC-50460) 是一种人 FPPS 和 UPPS 抑制剂，IC50值分别为 1.8 μM 和 110 nM，对金黄色葡萄球菌的 MIC 值大约为 250 ng/mL。
T33873	Pamidronate monosodium Pamidronic acid monosodium salt,J710.127I,Pamidronate-monosodium
	Pamidronate monosodium is a bisphosphonate.
T26928	BV600022 BV-600022,BV 600022
	BV600022 is an osteoadsorptive bisphosphonate-ciprofloxacin conjugate with antibacterial activity.
T28151	NE21650 NE-21650,NE 21650
	NE21650, a bisphosphonate, inhibits isopentenyl diphosphate isomerase and farnesyl diphosphate synthase.
T30836	Cgp 47072 Cgp-47072,Cgp47072
	Cgp 47072 is a bisphosphonate, used in the treatment of bone diseases, particularly where there is uncontrolled bone resorption.
T11956L	MBC-11	Others	Others
	MBC-11 is a first-in-class conjugate of the bone-targeting bisphosphonate etidronate covalently linked to the antimetabolite cytarabine (araC). It also has the potential to treat tumor-induced bone disease (TIBD).
T61764	Zoledronic acid disodium tetrahydrate
	Zoledronic Acid (Zoledronate) disodium tetrahydrate is a potent third-generation bisphosphonate (BP), exhibiting strong anti-resorptive activity. It effectively inhibits osteoclast differentiation and apoptosis, while also demonstrating anti-cancer properties [1].
T11956	MBC-11 triethylamine	Others	Others
	MBC-11 triethylamine has potential to treat tumor-induced bone disease (TIBD), is a first-in-class conjugate of the bone-targeting bisphosphonate etidronate covalently linked to the antimetabolite cytarabine (araC).
T11957	MBC-11 trisodium	Others	Others
	MBC-11 trisodium has potential to treat tumor-induced bone disease (TIBD).It is a first-in-class conjugate of the bone-targeting bisphosphonate HEDP covalently linked to the antimetabolite Ara-C.
T39037	Tiludronate disodium hemihydrate Tiludronic acid disodium hemihydrate,替鲁膦酸二钠半水合物
	Tiludronate (Tiludronic Acid) disodium hemihydrate is an orally active bisphosphonate compound that functions as an osteoregulator. It is primarily utilized in metabolic bone disorder research. This compound acts as a potent inhibitor of the osteoclast vacuolar H+ -ATPase and possesses antiresorptive and anti-inflammatory properties[4].
T73056	Tiludronate Tiludronic acid
	Tiludronate (Tiludronic Acid) 是一种口服活性双膦酸盐，可以起到骨调节作用。Tiludronate 用于代谢性骨疾病的研究。Tiludronate 是破骨细胞空泡 H(+)-ATP 酶的有效抑制剂。
T72989	hGGPPS-IN-3	Apoptosis	Apoptosis
	hGGPPS-IN-3（Compound 13h）是一种针对人类香叶基香叶基焦磷酸合成酶（hGGPPS）的有效抑制剂，属于C-2取代的噻吩并嘧啶基双膦酸盐（C2-ThP-BPs）衍生物。该化合物能够诱导多发性骨髓瘤（MM）细胞具有选择性地进入凋亡（apoptosis），并且在体内展现了对抗骨髓瘤的活性。
T70045	HUN47990
	HUN47990 is a bisphosphonate (BP) prodrug with antitumor activity. HUN47990 potently inhibits the in vitro growth of a variety of tumor cell lines, especially hematopoietic cell lines, at nanomolar concentrations. HUN47990 inhibited the prenylation of the RAP1A small GTPase signaling protein at concentrations as low as 1-10 nM. HUN47990 slowed the growth of human bladder cancer cells in an immunodeficient mouse model. HUN47990 is significantly more active than zoledronic acid, the most active FD...
T10586	BPH-1358 free base NSC50460 free base	Others	Others
	BPH-1358 (NSC50460) free base is a potent human undecaprenyl diphosphate synthase (UPPS) and farnesyl diphosphate synthase (FPPS) inhibitor (IC50s: 110 nM and 1.8 μM) and is active against S. aureus in vitro (MIC ~250 ng/mL).

化合物

Digeranyl bisphosphonate

Cat.No: T12452

Synonym: DGBP

Target: Rho, Ras

Aminobutane bisphosphonate

Cat.No: T69443

Zoledronic Acid

Cat.No: T6739

Synonym: CGP-4244,CGP42446A,唑来膦酸,Zoledronate,CGP 42446,ZOL 446,Zometa

Target: Apoptosis, Rho, Autophagy

Zoledronic acid monohydrate

Cat.No: T21299

Synonym: 唑来膦酸一水合物,zoledronate,ZOL 446,CGP 42446,CGP42446A,Zoledronic acid hydrate

Target: Apoptosis, Others, Autophagy

Ibandronic acid

Cat.No: T1599

Synonym: Bonviva,Bondronat,Boniva,伊班膦酸

Target: Others, HBV

Pamidronate Disodium

Cat.No: T1337

Synonym: 帕米膦酸钠,CGP 23339A,CGP 23339AE,Pamidronate disodium salt

Target: Others, HBV

Cat.No: T73506

Synonym: THZ93

Target: Antibacterial

Ibandronate sodium

Cat.No: T1599L

Synonym: 伊班膦酸钠,Boniva,Ibandronate sodium salt,Bondronat

Target: HBV, Transferase

Ibandronate sodium monohydrate

Cat.No: T6539

Synonym: Boniva monohydrate,Bondronat monohydrate,Ibandronate sodium,伊班膦酸钠单水合物,BM-210955,BM-21.0955,伊班膦酸钠一水合物,RPR-102289A

Target: Apoptosis, Others

Alendronate sodium hydrate

Cat.No: T6373

Synonym: G-704650,Alendronate,MK 217,Alendronate sodium trihydrate,阿仑膦酸钠,G-704650 Adronat,Fosamax

Target: Transferase

Clodronic acid disodium salt

Cat.No: T6451

Synonym: Loron,Clodronate Disodium,氯屈膦酸二钠,Lodronate

Target: Others

Cat.No: T16289

Synonym: 3-PEHPC

Target: Others

Cat.No: T19415

Synonym: 亚甲基二磷酸,Methylenediphosphonic acid

Target: Others

Cat.No: T14766

Target: Others, Parasite

Cat.No: T10586L

Synonym: NSC50460

Target: Others, Antibacterial

Pamidronate monosodium

Cat.No: T33873

Synonym: Pamidronic acid monosodium salt,J710.127I,Pamidronate-monosodium

Cat.No: T26928

Synonym: BV-600022,BV 600022

Cat.No: T28151

Synonym: NE-21650,NE 21650

Cat.No: T30836

Synonym: Cgp-47072,Cgp47072

Cat.No: T11956L

Target: Others

Zoledronic acid disodium tetrahydrate

Cat.No: T61764

MBC-11 triethylamine

Cat.No: T11956

Target: Others

MBC-11 trisodium

Cat.No: T11957

Target: Others

Tiludronate disodium hemihydrate

Cat.No: T39037

Synonym: Tiludronic acid disodium hemihydrate,替鲁膦酸二钠半水合物

Cat.No: T73056

Synonym: Tiludronic acid

Cat.No: T72989

Target: Apoptosis

Cat.No: T70045

BPH-1358 free base

Cat.No: T10586

Synonym: NSC50460 free base

Target: Others

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼