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Search Results for " tripterygium "

2

抑制剂 & 化合物

25

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T123808	Triptonoterpene
	Triptonoterpene 是在 Tripterygium wilfordii 和 Tripterygium doianum 中发现的一种天然产物。Triptonoterpene 是一种双乙烷二萜。
T26056	Regelinol
	Regelinol is a new antitumor ursene-type triterpenoid isolated from Tripterygium regelii.

化合物

Triptonoterpene

Cat.No: T123808

Cat.No: T26056

Cat. No.	Product Name	Target	Signaling Pathways
TN2141	Regelidine	Others	Others
	Regelidine 是一种天然产物，分离自雷公藤茎中。
T5S1058	Triptonide 雷公藤内酯酮,PG 492,NSC 165677	Apoptosis; Wnt/beta-catenin; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling; Stem Cells
	Triptonide (PG 492) 是从雷公藤中鉴定出的一种天然产物，是一种 Wnt 信号抑制剂，其 IC50约为 0.3 nM。它具有免疫抑制、抗炎、避育、神经保护和抗淋巴瘤作用。
T3393	Triptophenolide Hypolide,(+)-Triptophenolide,鼠尾草酸,雷酚内酯	Androgen Receptor	Endocrinology/Hormones
	Triptophenolide (Hypolide) 是一种无色晶体，从雷公藤的乙酸乙酯萃取部位分离得到。
T3418	Demethylzeylasteral 去甲泽拉木醛,Demethylzeylasteral (T-96)	Apoptosis; UGT	Apoptosis; Metabolism
	Demethylzeylasteral (Demethylzeylasteral (T-96)) 分离自雷公藤，具有抗炎、免疫抑制和抗肿瘤活性。它通过阻断 TGF-β 信号通路，抑制三阴性乳腺癌的侵袭，它能显著减轻动脉粥样硬化。
T3382	Wilforlide A Abruslactone A,雷公藤内酯甲,3-Epiabruslactone A,Regelide	Tyrosinase	Proteases/Proteasome
	Wilforlide A (3-Epiabruslactone A) 是一种具有生物活性的三萜，从雷公藤中分离得到，具有抗炎和免疫抑制活性。
T5S1054	Wilforgine 雷公藤晋碱,雷公藤精碱	Others	Others
	Wilforgine 是一种具有生物活性的倍半萜烯生物碱，存在于Tripterygium wilfordiiHook. F 中。它能诱导分离出丝状体幼虫肌肉的微结构和超微结构变化，其作用部位被认为是肌肉系统中的钙受体或通道。
TN5255	Wilforol A	Others	Others
	Wilforol A is a natural product from Tripterygium wilfordii Hook. f.
T83434	1b-Benzoyl-8a-cinnamoyl-4a,5a-dihydroxydihydroagarofuran
	1b-Benzoyl-8a-cinnamoyl-4a,5a-dihydroxydihydroagarofuran是Tripterygium hypoglaucum根皮中提取的一种倍半萜化合物，其结构特征包括一个苯甲酰基团与一个肉桂酰基团。
T80940	Triptonoterpenol
	Triptonoterpenol（化合物6）是雷公藤（Tripterygium wilfordii）的一种次级代谢产物。
TN5185	Triptonodiol	Others	Others
	Triptonodiol is a natural product from Tripterygium wilfordii Hook.f.
TN5188	Triptoquinonide	Others	Others
	Triptoquinonide is a natural product from Tripterygium wilfordii.
T80942	Triptonoditerpenic acid
	Triptonoditerpenic acid 为一芳香族松香烷二萜类化合物，源自Tripterygium wilfordii。该化合物对HepG2、Hep3B 及 Bcap37细胞株展现细胞毒性作用，其IC50值依次为42.53 μM、29.74 μM 与37.63 μM。
T26055	Regelin Regelin C
	Regelin is an antitumor ursene-type triterpenoid isolated from Tripterygium regelii.
T80941	Triptonoterpene Me ether
	Triptonoterpene Me ether（compound 5）为一种从中药雷公藤（Tripterygium wilfordii Hook. f.）分离出的松香烷型二萜类化合物。
TN5960	Polpunonic acid Maytenonic acid,美登木酸,Maytenoic acid
	Polpunonic acid is a natural product from Tripterygium wilfordii Hook.f.
T80939	Triptoquinone H
	Triptoquinone H是从雷公藤中提取的天然产物，显示出显著的细胞毒性、免疫调节作用和抗炎活性，适用于癌症和炎症疾病的研究。
T40252	Peritassine A
	Peritassine A, an alkaloid derived from Tripterygium wilfordii Hook. f., exhibits anti-HIV properties.
T27174	Dihydrocelastrol DHCE. (-)-Triptohypol C,Triptohypol C
	Dihydrocelastrol is synthesized by hydrogenation of celastrol, a treterpene isolated from Chinese medicinal plant Tripterygium regelii. Dihydrocelastrol could inhibit cell proliferation and promote apoptosis through caspase-dependent way in vitro. DHCE co
T13936	Triptotriterpenic acid A Maytenfolic acid,Abrusgenic acid	Others	Others
	Triptotriterpenic acid A is a natural product isolate from Tripterygium wilfordii.
TMA0925	Wilforlide A acetate	Others	Others
	Wilforlide A (T1) serves as a quality control standard of Tripterygium Glycosides that be listed in Drug Standard of Ministry of Public Health of the People's Republic of China. T1 has anti-inflammatory effects.
T80938	Triptotriterpenic acid C
	Triptotriterpenic acid C, 提取自雷公藤根部, 属于乌索酸类化合物。
TN1987	Neotriptophenolide 雷酚新内酯,新三苯酚	Others	Others
	Neotriptophenolide 是一种倍半萜吡啶生物碱，分离自雷公藤的根皮中。
TN2283	Tripterifordin	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Tripterifordin 在 H9 淋巴细胞中显示出抗 HIV 复制活性，EC50值为 3100 nM。
T2179	Triptolide PG490,NSC 163062,雷公藤甲素	Apoptosis; Mdm2; HSP; NF-κB	Apoptosis; Cytoskeletal Signaling; Metabolism; NF-κB
	Triptolide (PG490) 属于三环二萜类天然产物，是一种 NF-κB 活化的抑制剂。Triptolide 具有免疫抑制、抗风湿、抗炎、抗增殖和抗肿瘤活性。
T4S1050	Pristimerin 扁塑藤素,Celastrol methyl ester	NF-κB; Antibacterial	Microbiology/Virology; NF-κB
	Pristimerin (Celastrol methyl ester) 是一种可逆的单酰基甘油脂肪酶高效抑制剂，IC50值为93 nM。

天然产物

Cat.No: TN2141

Target: Others

Cat.No: T5S1058

Synonym: 雷公藤内酯酮,PG 492,NSC 165677

Target: Apoptosis, Wnt/beta-catenin, Autophagy

Triptophenolide

Cat.No: T3393

Synonym: Hypolide,(+)-Triptophenolide,鼠尾草酸,雷酚内酯

Target: Androgen Receptor

Demethylzeylasteral

Cat.No: T3418

Synonym: 去甲泽拉木醛,Demethylzeylasteral (T-96)

Target: Apoptosis, UGT

Cat.No: T3382

Synonym: Abruslactone A,雷公藤内酯甲,3-Epiabruslactone A,Regelide

Target: Tyrosinase

Cat.No: T5S1054

Synonym: 雷公藤晋碱,雷公藤精碱

Target: Others

Cat.No: TN5255

Target: Others

1b-Benzoyl-8a-cinnamoyl-4a,5a-dihydroxydihydroagarofuran

Cat.No: T83434

Triptonoterpenol

Cat.No: T80940

Cat.No: TN5185

Target: Others

Triptoquinonide

Cat.No: TN5188

Target: Others

Triptonoditerpenic acid

Cat.No: T80942

Cat.No: T26055

Synonym: Regelin C

Triptonoterpene Me ether

Cat.No: T80941

Polpunonic acid

Cat.No: TN5960

Synonym: Maytenonic acid,美登木酸,Maytenoic acid

Triptoquinone H

Cat.No: T80939

Cat.No: T40252

Dihydrocelastrol

Cat.No: T27174

Synonym: DHCE. (-)-Triptohypol C,Triptohypol C

Triptotriterpenic acid A

Cat.No: T13936

Synonym: Maytenfolic acid,Abrusgenic acid

Target: Others

Wilforlide A acetate

Cat.No: TMA0925

Target: Others

Triptotriterpenic acid C

Cat.No: T80938

Neotriptophenolide

Cat.No: TN1987

Synonym: 雷酚新内酯,新三苯酚

Target: Others

Cat.No: TN2283

Target: HIV Protease

Cat.No: T2179

Synonym: PG490,NSC 163062,雷公藤甲素

Target: Apoptosis, Mdm2, HSP, NF-κB

Cat.No: T4S1050

Synonym: 扁塑藤素,Celastrol methyl ester

Target: NF-κB, Antibacterial

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