Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2279 |
Tizoxanide
替唑尼特,Desacetyl-nitazoxanide,TIZ |
Antiviral; HIV Protease; Antibacterial; Autophagy | Autophagy; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome |
Tizoxanide (Desacetyl-nitazoxanide) 是 Nitazoxanide 活性代谢物,有抗HIV-1的活性。Nitazoxanide 可抗细菌和多种病毒复制。 | |||
T4093 |
Fabomotizole hydrochloride
Afobazole hydrochloride,CM346 hydrochloride |
MAO | Metabolism; Neuroscience |
Fabomotizole hydrochloride (CM346 hydrochloride) 是一种具有抗焦虑和神经保护作用的化合物。 | |||
T8567 |
amflutizole
|
Xanthine Oxidase | Metabolism |
amflutizole 用于治疗痛风,是一种黄嘌呤氧化酶抑制剂。 | |||
T7527 |
Frentizole
|
Beta Amyloid | Neuroscience |
Frentizole 是一种 FDA 批准的免疫抑制剂,是一种新型 Aβ-ABAD 相互作用抑制剂。 | |||
T8608 |
Fanetizole
|
Others | Others |
Fanetizole 显示出免疫调节活性。 | |||
T1864 |
Fabomotizole
Obenoxazine,CM346,4-(2-(5-乙氧基-1H-苯并[D]咪唑-2-基硫代)乙基)吗啉 |
Others | Others |
Fabomotizole (Obenoxazine) 是一种抗焦虑药物,具有抗焦虑和神经保护作用,且无镇静和肌肉松弛作用。 | |||
T7065 |
Tizanidine
|
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Tizanidine 是一种 α2-肾上腺素受体激动剂,能够抑制神经递质从CNS 去甲肾上腺素激活的神经元中释放。 | |||
T4501 |
Ceftizoxime
头孢唑肟,Epocelin |
Antibacterial; Antibiotic | Microbiology/Virology |
Ceftizoxime (Epocelin) 是一种强效抗菌剂,它通过干扰细菌细胞壁合成和抑制肽聚糖的交联起作用。它对广谱的 β-内酰胺酶具有高度抗性,并且对多种需氧和厌氧的革兰氏阳性和革兰氏阴性微生物均有效。 | |||
T0290 |
Tizanidine hydrochloride
盐酸替扎尼定,Tizanidine HCl,DS 103-282 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Tizanidine hydrochloride (Tizanidine HCl) 是一种 α2-肾上腺素受体激动剂,可抑制神经递质从 CNS 去甲肾上腺素激活的神经元中释放。 | |||
T10429 |
Tizaterkib
AZD-0364 |
ERK | MAPK |
Tizaterkib (AZD-0364) 是一种选择性ERK2抑制剂,IC50为 0.6 nM。 | |||
T25919 |
Paraflutizide
LD3612,LD 3612,Paraflutizida,LD-3612 |
||
Paraflutizide is a thiazide analog antihypertensive. | |||
T82997 |
Antitumor photosensitizer-2
|
||
Antitumor photosensitizer-2(Compound 11)是一款高效光敏剂,表现出显著的光动力学抗肿瘤活性,并且不具有明显的皮肤光毒性,是光动力学治疗领域新药开发的候选物。 | |||
T75352 | Photosensitizer-1 | ||
Photosensitizer-1 (Compound CLB-13) 是一个光敏剂。 | |||
T73218 | Epitizide | ||
Epitizide 是一种苯并噻二嗪,常与Triamterene 联合使用,产生利尿作用。 | |||
T79711 |
Antitumor photosensitizer-4
|
Apoptosis | Apoptosis |
Antitumor photosensitizer-4 (compound 10b) 是靶向ABCG2酪氨酸激酶抑制剂(TKI)的有效代表,由达沙替尼与伊马替尼构成的光敏剂(PS)。该化合物能够诱发细胞凋亡(apoptosis)及ROS生成,在HepG2和B16-F10细胞上展现出显著的光毒性作用。 | |||
T70073 |
Fabomotizole dihydrochloride
|
||
Fabomotizole, also known as Afobazole, Obenoxazine and CM346, is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be al... | |||
T82998 |
Antitumor photosensitizer-1
|
||
Antitumor photosensitizer-1(Compound 8)是一种高效的光敏化合物,展现出显著的光动力治疗肿瘤能力,且没有显著的皮肤光毒性反应,是一个潜在的光动力疗法新候选药物。 | |||
T131612 |
Isotalatizidine
|
||
Isotalatizidine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131612。 | |||
T74392 | Antimicrobial photosensitizer-1 | ||
Antimicrobial photosensitizer-1 为抗病原微生物感染的潜在光敏剂,其在金黄色葡萄球菌感染小鼠伤口模型中显示出显著的抗菌活性。 | |||
T19646 |
Altizide
CB-8093,Aldactacine,P 1779,CB 8093,P1779,P-1779 |
||
Altizide is a thiazide diuretic. It is used to treat oedema and hypertension. | |||
T74601 | Antitumor photosensitizer-3 | ||
Antitumor photosensitizer-3(Compound I)是一种二氢卟酚衍生物,能在650 nm激光照射下诱导肿瘤细胞的凋亡和坏死。与阳性参考m-THPC相比,Antitumor photosensitizer-3在体内的皮肤光毒性较低。 | |||
T21386 |
Ceftizoxime Sodium
Epocelin,Eposerin,Monosodium Salt, Ceftizoxime,Cefizox,头孢唑肟钠,Ceftizoxime sodium salt,Ceftizoxim-natrium |
||
Ceftizoxime, a third-generation cephalosporin effective against Gram-negative and Gram-positive bacteria, binds penicillin-binding proteins (PBPs) to inhibit the bacterial cell wall synthesis. It rather resembles cefotaxime in its properties but is not su | |||
T8608L |
Fanetizole mesylate
UNII-D3OG7B0G4M,CP 48810,Fanetizole mesylate (USAN),C1MHW3X |
||
Fanetizole mesylate is an immunoregulator agent. | |||
T60816 |
Protizinic acid
|
||
Protizinic acid 抑制磷脂酶 A2 (PLA2),IC50值为 210 μM。Protizinic acid 是具有抗炎和解热活性的,口服非甾体抗炎剂。 | |||
T75353 | Photosensitizer-1 hydrochloride | ||
Photosensitizer-1 (Compound CLB-13) hydrochloride 是一个光敏剂。 | |||
T69054 |
Ciclotizolam
|
||
Ciclotizolam is a drug which is a thienotriazolodiazepine derivative. It is a partial agonist for the benzodiazepine site of the GABAA receptor, with similar binding affinity to related compounds like brotizolam, but a low efficacy. | |||
T81483 |
Photosensitizer-2
|
||
Photosensitizer-2 (化合物 1) 是一种带有丙烯酸基团的 D-π-A 光敏剂,显示出高度的光毒性。该化合物对 HeLa 细胞表现出抗肿瘤效果,其半数抑制浓度(IC50)为20.9 ± 4.5 μM(未照光条件下)和0.046 ± 0.012 μM(光照射条件下)。 |