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16

抑制剂 & 化合物

16

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T80944 Tripeptide-10 citrulline

T10-C

Tripeptide-10 citrulline(T10-C),一种生物活性肽,具备抗衰老(anti-aging)功能,广泛应用于化妆品成分。
T67872 VT104

YAP Stem Cells
VT104是一种有效的YAP/TAZ 抑制剂,具有口服活性,可用于癌症研究。VT104阻止内源性TEAD1和TEAD3蛋白棕榈酰化。
T15000 Cort108297

Glucocorticoid Receptor Endocrinology/Hormones
Cort108297是一种选择性糖皮质激素受体调节剂,也是一种对其他类固醇受体无亲和力的选择性GR 拮抗剂。Cort108297对gr 具有较高的亲和力(Ki: 0.45 nM)。
T27404 GAT107

GAT 107,GAT-107

AChR Neuroscience
GAT107 是一种新型有效的 α7 烟碱胆碱能受体变构激动剂和调节剂,具有抗炎活性,可逆转小鼠神经疼痛模型中的伤害感受。
T35545 VT107

YAP Stem Cells
VT107 是一种强效的泛 TEAD 自身棕榈酰化抑制剂。VT-107 可用于癌症研究。
T62077 VT103

VT-103,VT 103

YAP Stem Cells
VT103 是一种具有口服活性和选择性的 TEAD1 蛋白棕榈酰化抑制剂,是 VT101 的类似物。 VT103 有潜在的抗肿瘤活性,可抑制 YAP/TAZ-TEAD 促进的基因转录,阻断 TEAD auto-palmitoylation,阻断 YAP/TAZ和TEAD 之间的相互作用。VT103 可用于研究HER2阳性乳腺癌、前列腺癌和三阴性乳腺癌。
T38148 (S)-KT109

(S)-KT109

(S)-KT109 is the (S) isomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109 . (S)-KT109 is a less potent inhibitor of DAGLβ (IC50 = 39.81 nM), DAGLα-mediated hydrolysis of 1-stearoyl-2-arachidonoyl-sn-glycerol (IC50 = 794.3 nM), and α/β-hydrolase domain-containing protein 6 (ABHD6; IC50 = 630.9 nM) than (R)-KT109 .
T70301 GAT100

GAT100 is a potent and covalent negative allosteric modulator (NAM). GAT-100 behaved as a robust positive allosteric modulator of binding of orthosteric agonist CP55,940. This novel covalent probe can serve as a useful tool for characterizing CB1R allosteric ligand-binding motifs.
T81102 ST1074

Apoptosis Apoptosis
ST1074为CerS2/CerS4双重抑制剂,能够诱导细胞凋亡,常用于癌症研究。
T72016 ST101036

MC activators have recently been described as safe and effective vaccine adjuvants. ST101036 exhibited high degranulation potency in both human and mouse MCs.
T69080 T1001

T1001 is an antagonist of hypoxia-inducible factor-2α subunit (HIF-2α) which displaces residue M252 from inside the HIF-2α PAS-B pocket toward the ARNT subunit to weaken heterodimerization.
T68934 VT101 free base

VT101 is a TEAD Auto-palmitoylation inhibitor that Selectively Inhibit Proliferation and Tumor Growth of NF2-deficient Mesothelioma. VT101 inhibited the firefly luciferase reporter dose-dependently and had no 204 effect on the Renilla luciferase reporter.
T27752 KT109

KT-109,KT 109

KT109 is a selective inhibitor of DAGLβ (IC50 = 42 nM). KT109-treated wild-type mice displayed reductions in LPS-induced allodyni as well as in DAGL-β (-/-) micea. Repeated KT109 administration prevented the expression of LPS-induced allodynia, without ev
T79188 BT100

Integrin Cytoskeletal Signaling
BT100 为一核酸适配体,能够抑制血管性血友病因子(von Willebrand factor, VWF)与血小板糖蛋白GPIb之间的结合,旨在预防动脉血栓的形成。
T27558 HT1042

HT 1042,HT-1042

HT1042 is an inhibitor of the β5i component of the 20S proteasome complex, it is used to aid in the treatment of inflammatory diseases, autoimmune and hematologic malignancies.
T38031 (R)-KT109

(R)-KT109

(R)-KT109 is the (R) isomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109 . (R)-KT109 is an inhibitor of DAGLβ (IC50 = 0.79 nM) and of DAGLα-mediated hydrolysis of 1-stearoyl-2-arachidonoyl-sn-glycerol . It also inhibits α/β-hydrolase domain-containing protein 6 (ABHD6) with an IC50 value of 2.51 nM. (R)-KT109 is more potent at DAGLβ, DAGLα, and ABHD6 than (S)-KT109 .

化合物

Tripeptide-10 citrulline
Cat.No: T80944
Synonym: T10-C
Target:
VT104
Cat.No: T67872
Synonym:
Target: YAP
Cort108297
Cat.No: T15000
Synonym:
Target: Glucocorticoid Receptor
GAT107
Cat.No: T27404
Synonym: GAT 107,GAT-107
Target: AChR
VT107
Cat.No: T35545
Synonym:
Target: YAP
VT103
Cat.No: T62077
Synonym: VT-103,VT 103
Target: YAP
(S)-KT109
Cat.No: T38148
Synonym: (S)-KT109
Target:
GAT100
Cat.No: T70301
Synonym:
Target:
ST1074
Cat.No: T81102
Synonym:
Target: Apoptosis
ST101036
Cat.No: T72016
Synonym:
Target:
T1001
Cat.No: T69080
Synonym:
Target:
VT101 free base
Cat.No: T68934
Synonym:
Target:
KT109
Cat.No: T27752
Synonym: KT-109,KT 109
Target:
BT100
Cat.No: T79188
Synonym:
Target: Integrin
HT1042
Cat.No: T27558
Synonym: HT 1042,HT-1042
Target:
(R)-KT109
Cat.No: T38031
Synonym: (R)-KT109
Target:
Cat. No. Product Name Species Expression System
TMPY-01023 CD38 Protein, Human, Recombinant (His)

CD38 molecule,ADPRC1,ADPRC 1,T10

Human HEK293 Cells
CD38 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.3 kDa and the accession number is P28907-1.
TMPY-05573 CD38 Protein, Human, Recombinant (His), PE conjugated

T10,ADPRC1,ADPRC 1,CD38 molecule

Human HEK293 Cells
CD38 Protein, Human, Recombinant (His), PE conjugated is expressed in HEK293 mammalian cells with His tag. The accession number is NP_001766.2.
TMPY-05273 CD38 Protein, Human, Recombinant (hFc)

ADPRC1,CD38 molecule,T10,ADPRC 1

Human HEK293 Cells
CD38 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.6 kDa and the accession number is P28907-1.
TMPY-02776 CD38 Protein, Human, Recombinant (His & FLAG)

T10,CD38 molecule,ADPRC 1,ADPRC1

Human HEK293 Cells
CD38 Protein, Human, Recombinant (His & FLAG) is expressed in HEK293 mammalian cells with His and Flag tag. The predicted molecular weight is 33.2 kDa and the accession number is P28907-1.
TMPY-05574 CD38 Protein, Human, Recombinant (His), FITC conjugated

CD38 molecule,T10,ADPRC 1,ADPRC1

Human HEK293 Cells
CD38 Protein, Human, Recombinant (His), FITC conjugated is expressed in HEK293 mammalian cells with His tag. The accession number is NP_001766.2.
TMPY-06811 CD38 Protein, Human, Recombinant (hFc & Avi), Biotinylated

CD38 molecule,T10,ADPRC1,ADPRC 1

Human HEK293 Cells
CD38 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 58.41 kDa and the accession number is NP_001766.2.
TMPY-05606 CD38 Protein, Human, Recombinant (His & Avi), Biotinylated

ADPRC 1,T10,CD38 molecule,ADPRC1

Human HEK293 Cells
CD38 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 33.1 kDa and the accession number is P28907-1.
TMPJ-00190 CD38 Protein, Mouse, Recombinant (hFc)

ADP-ribosyl cyclase 1,cyclic ADP-ribose hydrolase,T10

Mouse HEK293 Cells
CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Th...
TMPH-02857 Wnt10a Protein, Mouse, Recombinant (His & Myc)

Mouse E. coli
Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Plays a role in normal ectoderm development. Required for normal tooth development. Required for normal postnatal development and maintenance of tongue papillae and sweat ducts. Required for normal proliferation of basal cells in tongue filiform papillae, plantar epithelium and sweat ducts. Required for normal expression of keratins in tongue papillae. Requir...
TMPY-01343 FUT10 Protein, Human, Recombinant (His)

fucosyltransferase 10 (alpha (1,3) fucosyltransferase),fucos...

Human HEK293 Cells
FUT10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.7 kDa and the accession number is Q6P4F1-1.
TMPY-06429 SARS-CoV-2 Spike S1+S2 Protein (P26S, 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H & T1027I & D1118H, His)

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (P26S, 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H & T1027I & D1118H, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 133.72 kDa and the accession number is A0A6G7K2L4.
TMPY-03049 GALNT10 Protein, Human, Recombinant (His)

GALNACT10,PPGANTASE10,polypeptide N-acetylgalactosa...

Human HEK293 Cells
Ectopic expression and knockdown studies showed that GALNT10 indeed promotes proliferation and apoptosis resistance of hepatoma cells in a glycosyltransferase-dependent manner. The genetic variants on LEKR1 and GALNT10 genes have been associated with control of adiposity and weight.
TMPH-01575 KRT10 Protein, Human, Recombinant (His)

Human E. coli
Plays a role in the establishment of the epidermal barrier on plantar skin.; (Microbial infection) Acts as a mediator of S.aureus adherence to desquamated nasal epithelial cells via clfB, and hence may play a role in nasal colonization.; (Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Reduction of levels of KRT10 keratin decrease adherence, overexpression increases adherence. Neither protein has to be glycosylated for the interaction to occu...
TMPH-01957 Wnt10a Protein, Human, Recombinant (His)

Human P. pastoris (Yeast)
Wnt10a Protein, Human, Recombinant (His) is expressed in Yeast.
TMPY-06159 SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I & V1176F, His)

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I & V1176F, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.5 kDa and the accession number is A0A6G7K2L4.
TMPY-06131 SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I, His)

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.4 kDa and the accession number is A0A6G7K2L4.

重组蛋白

CD38 Protein, Human, Recombinant (His)
Cat.No: TMPY-01023
Species: Human
Expression System: HEK293 Cells
CD38 Protein, Human, Recombinant (His), PE conjugated
Cat.No: TMPY-05573
Species: Human
Expression System: HEK293 Cells
CD38 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05273
Species: Human
Expression System: HEK293 Cells
CD38 Protein, Human, Recombinant (His & FLAG)
Cat.No: TMPY-02776
Species: Human
Expression System: HEK293 Cells
CD38 Protein, Human, Recombinant (His), FITC conjugated
Cat.No: TMPY-05574
Species: Human
Expression System: HEK293 Cells
CD38 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06811
Species: Human
Expression System: HEK293 Cells
CD38 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05606
Species: Human
Expression System: HEK293 Cells
CD38 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00190
Species: Mouse
Expression System: HEK293 Cells
Wnt10a Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02857
Species: Mouse
Expression System: E. coli
FUT10 Protein, Human, Recombinant (His)
Cat.No: TMPY-01343
Species: Human
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1+S2 Protein (P26S, 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H & T1027I & D1118H, His)
Cat.No: TMPY-06429
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
GALNT10 Protein, Human, Recombinant (His)
Cat.No: TMPY-03049
Species: Human
Expression System: HEK293 Cells
KRT10 Protein, Human, Recombinant (His)
Cat.No: TMPH-01575
Species: Human
Expression System: E. coli
Wnt10a Protein, Human, Recombinant (His)
Cat.No: TMPH-01957
Species: Human
Expression System: P. pastoris (Yeast)
SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I & V1176F, His)
Cat.No: TMPY-06159
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I, His)
Cat.No: TMPY-06131
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
TargetMol Loading
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