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Search Results for " st2 "

Targets Recommended: Wnt/beta-catenin

7

抑制剂 & 化合物

1

TargetMol 试剂盒

18

重组蛋白

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Cat. No.	Product Name	Form	Specificity Of Inhibition
CEPY-0005	Human Cystatin SA/CST2 ELISA Pair Set Human Cystatin SA/CST2 ELISA 抗体对

TargetMol 试剂盒

Human Cystatin SA/CST2 ELISA 抗体对

Cat.No: CEPY-0005

Cat. No.	Product Name	Target	Signaling Pathways
T9988	Wnt/β-catenin agonist 3	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	Wnt/β-catenin agonist 3是一种Wnt/beta-catenin 信号通路激动剂。
T20920	PST2286 PST 2286,17Hydroxydigitoxigenin,17-Hydroxydigitoxigenin,17 Hydroxydigitoxigenin,PST-2286	Others	Others
	PST2286 (17-Hydroxydigitoxigenin) 是一种罗他福辛代谢物。
T4511	ST271 ST 271	Phospholipase; Tyrosine Kinases	Metabolism; Tyrosine Kinase/Adaptors
	ST271 是蛋白质酪氨酸激酶 (PTK) 抑制剂，抑制 fMet-Leu-Phe 和 PAF 引起的 phospholipase D 活化的IC50值分别为 6.7 和 9 μM。
T72015	iST2-1
	iST2-1 is a first-in-class ST2 inhibitor active in vivo.
T62321	ST247
	ST247 是一种有效的 PPARβ/δ 反向激动剂，对 PPARβ/δ 具有较高的亲和力，能够反向调控激活标记物 CCL2 的表达。ST247 对激动剂诱导的 PPARβ/δ 的转录活性具有抑制作用。ST247 能够有效诱导与辅抑制子的相互作用。
T77083	Melrilimab
	Melrilimab (GSK 3772847)为一种针对IL1RL1/ST2/IL33R/DER4/FIT-1的IgG2-kappa型单克隆抗体，主要应用于哮喘研究。
T80759	XY-52
	XY-52（Compound 32）是ST2抑制剂，AlphaLISA实验中IC50为5.68μM，HEK-Blue实验中为4.59μM。该化合物能提升促炎性T细胞增殖，并在移植物抗宿主病（GVHD）小鼠模型中降低血浆sST2与IFNγ生物标志物水平。

化合物

Wnt/β-catenin agonist 3

Cat.No: T9988

Target: Wnt/beta-catenin

Cat.No: T20920

Synonym: PST 2286,17Hydroxydigitoxigenin,17-Hydroxydigitoxigenin,17 Hydroxydigitoxigenin,PST-2286

Target: Others

Cat.No: T4511

Synonym: ST 271

Target: Phospholipase, Tyrosine Kinases

Cat.No: T72015

Cat.No: T62321

Cat.No: T77083

Cat.No: T80759

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04096	ST2/IL-1 RL1 Protein, Mouse, Recombinant (His) Ly84,St2-rs1,T1,ST2L,T1/...	Mouse	HEK293 Cells
	ST2/IL-1 RL1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is P14719-1.
TMPY-00850	ST2/IL-1 RL1 Protein, Human, Recombinant ST2,IL1RL1,ST2L,IL33R,T1...	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.6 kDa and the accession number is Q01638-2.
TMPY-01359	ST2/IL-1 RL1 Protein, Human, Recombinant (His) IL1RL1,IL‑1 R4,DER4,ST2,IL33R,interleukin ...	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2.
TMPY-00849	ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) ST2V,FIT-1,DER4,interleukin 1 receptor-lik...	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.72 kDa and the accession number is Q01638-2.
TMPJ-00850	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) Protein T1,suppression of tumorigenicity 2,Ly84,DER...	Mouse	HEK293 Cells
	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
TMPY-03493	ST2/IL-1 RL1 Protein, Mouse, Recombinant (hFc) St2,ST2L,T1/ST<...	Mouse	HEK293 Cells
	ST2/IL-1 RL1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.8 kDa and the accession number is P14719-1.
TMPY-02147	ST2/IL-1 RL1 Protein, Human, Recombinant (isoform a, His) ST2L,FIT-1,IL‑1 R4,interleukin 1 receptor-...	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant (isoform a, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.3 kDa and the accession number is Q01638-1.
TMPJ-00849	ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc) Protein ST2,IL-1 R4,IL-33R,ST...	Mouse	HEK293 Cells
	ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-110 KDa and the accession number is P14719-2.
TMPY-01587	SULT2A1 Protein, Human, Recombinant (His) hSTa,HST,ST2,ST...	Human	E. coli
	Hydroxysteroid sulfotransferase ( SULT2A1 ) is a key enzyme in the testicular and hepatic metabolism of 5alpha-androstenone, which is a major component of the off-odor and off-flavor in pork known as boar taint. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar amon...
TMPY-05452	ST2/IL-1 RL1 Protein, Cynomolgus, Recombinant (His) interleukin 1 receptor-like 1	Cynomolgus	HEK293 Cells
	ST2/IL-1 RL1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.1 kDa and the accession number is XP_005575214.1.
TMPY-03235	BST2 Protein, Human, Recombinant (His) bone marrow stromal cell antigen 2,CD317,T...	Human	HEK293 Cells
	BST2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.9 kDa and the accession number is Q10589.
TMPY-02510	HIST2H2BE Protein, Human, Recombinant MGC129734,H2BGL105,H2B.1,hist...	Human	E. coli
	Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. Histone proteins exhibit two levels of diversity: 1. evolutionary diversity between species and 2. subtype diversity in a class(H1, H2A, H2B, H3 or H4) within a species. It has become more and more evident that histone modifications are key players in the regulation of chromatin states and dynamics as well as in gene expression. Therefore, histone modifications and the enz...
TMPY-04742	BST2 Protein, Mouse, Recombinant (His) Bst-2,GREG,bone marrow stromal ce...	Mouse	HEK293 Cells
	BST2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.6 kDa and the accession number is Q8R2Q8.
TMPK-01298	BST2 Protein, Cynomolgus, Recombinant (His) HM1.24 antigen,PDCA-1,BST2,TETHER...	Cynomolgus	HEK293 Cells
	Interferon-induced BST2 (bone marrow stromal cell antigen 2) inhibits viral replication by tethering enveloped virions to the cell surface to restrict viral release and by inducing the NFKB-dependent antiviral immune response. BST2 expression was significantly increased during porcine epidemic diarrhea virus (PEDV) infection of Vero cells by IRF1 targeting its promoter. Both the BST2 and N protein interacted with the E3 ubiquitin ligase MARCHF8/MARCH8 and the cargo receptor.
TMPY-03193	BST2 Protein, Human, Recombinant (hFc) CD317,TETHERIN,bone marrow stromal cell antigen	Human	HEK293 Cells
	BST2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is Q10589.
TMPY-02674	BST2 Protein, Mouse, Recombinant (hFc) 2310015I10Rik,bone marrow stromal cell ant...	Mouse	HEK293 Cells
	BST2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40 kDa and the accession number is Q8R2Q8.
TMPK-00163	IL-33 Protein, Cynomolgus, Recombinant (His) IL1F11,C9orf26 Z,C9ORF26,DV27,RP1...	Cynomolgus	HEK293 Cells
	Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellular nucleus in several tissues. High levels of IL-33 are expressed in epithelial barrier tissues and endothelial barriers. ST2 is a receptor for IL-33, expressed selectively on a subset of Th2 cells, mediating some of their functions.
TMPJ-00617	IL-33 Protein, Rhesus macaque, Recombinant (His) Interleukin-33,IL1F11,IL33,白介素,白细胞介素,IL-1F11,Interleukin-1 F...	Rhesus	E. coli
	Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways...

重组蛋白

ST2/IL-1 RL1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04096

Species: Mouse

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Human, Recombinant

Cat.No: TMPY-00850

Species: Human

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01359

Species: Human

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00849

Species: Human

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)

Cat.No: TMPJ-00850

Species: Mouse

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03493

Species: Mouse

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Human, Recombinant (isoform a, His)

Cat.No: TMPY-02147

Species: Human

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc)

Cat.No: TMPJ-00849

Species: Mouse

Expression System: HEK293 Cells

SULT2A1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01587

Species: Human

Expression System: E. coli

ST2/IL-1 RL1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-05452

Species: Cynomolgus

Expression System: HEK293 Cells

BST2 Protein, Human, Recombinant (His)

Cat.No: TMPY-03235

Species: Human

Expression System: HEK293 Cells

HIST2H2BE Protein, Human, Recombinant

Cat.No: TMPY-02510

Species: Human

Expression System: E. coli

BST2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04742

Species: Mouse

Expression System: HEK293 Cells

BST2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01298

Species: Cynomolgus

Expression System: HEK293 Cells

BST2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03193

Species: Human

Expression System: HEK293 Cells

BST2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02674

Species: Mouse

Expression System: HEK293 Cells

IL-33 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00163

Species: Cynomolgus

Expression System: HEK293 Cells

IL-33 Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPJ-00617

Species: Rhesus

Expression System: E. coli

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