Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0942 |
Quinacrine dihydrochloride
疟疾平,Mepacrine dihydrochloride,阿的平,SN-390,Quinacrine 2HCl |
Apoptosis; Mitophagy; DNA; Phospholipase; Parasite; Autophagy; Histamine Receptor | Apoptosis; Autophagy; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience |
Quinacrine dihydrochloride (Mepacrine dihydrochloride) 是一种具有口服活性的抗疟剂,抑制 NF-κB 并激活 p53 信号转导,诱导肿瘤细胞发生凋亡,具有抗肿瘤和抗寄生虫活性。 | |||
T37031 |
Quinacrine mustard hydrochloride
Quinacrine mustard HCl |
Autophagy | Autophagy |
Quinacrine mustard hydrochloride 是一种荧光染料,也 是一种多环芳香剂,可作为诱变剂诱导细菌的突变体。Quinacrine mustard hydrochloride 能选择性地与腺嘌呤-胸腺嘧啶(AT)碱基对结合,而不 是与鸟嘌呤-胞嘧啶(GC)碱基对结合,诱导细胞周期停滞在 G2/M 期。Quinacrine mustard (hydrochloride) 已被用于标记移相染色体,以通过自动放射摄影技术进行核型分析。 | |||
T23210 |
Quinacrine (dihydrochloride hydrate)
Quinacrine (hydrochloride hydrate) (83-89-6 free base) |
Others | Others |
Quinacrine is a compound that is commonly used as an anti-protozoal agent. It inhibits voltage-dependent sodium channels (IC50: 3.3 μM) and suppresses aldehyde oxidase (IC50: 3.3 μM). Quinacrine prevents misfolding of prion protein (EC50: 0.3 μM). As an e | |||
T22412 |
Quinacrine hydrochloride hydrate
Mepacrine Dihydrochloride Dihydrate,米帕林盐酸盐,Quinacrine Dihydrochloride Dihydrate |
Others | Others |
Quinacrine, a dye of the acridine family, has been widely used as staining agents for DNA and model compounds for intercalators in numerous biophysical studies. It is also an antimalarial drug. | |||
T35747 |
Quinacrine analog 34
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Quinacrine is a compound with multiple actions that is commonly used as an anti-protozoal agent. It has also been shown to be a highly potent autophagy inhibitor, although the dose required to achieve this effect is considerably cytotoxic (LD50 = 2.5 μM). Quinacrine analog 34 is a derivative of quinacrine that was designed with an improved cell viability profile (LD50 = 27 μM) to inhibit autophagy. At a minimum concentration of 0.5 μM, this compound has been shown to increase the protein levels ... | |||
T34224 |
Quinacrine methanesulfonate
Mepacrine dimethanesulfonate salt |
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Quinacrine methanesulfonate is a bioactive chemical. | |||
T68694 |
Quinacrine acetate
|
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Quinacrine acetate is a histamine N-methyltransferase inhibitor. | |||
T10931 |
d-Atabrine dihydrochloride
|
Others | Others |
d-Atabrine hydrochloride is the active enantiomer of quinacrine and has anti-pr virus activity. | |||
T11801 |
l-Atabrine dihydrochloride
|
Others | Others |
l-Atabrine dihydrochloride displays antiprion activity. l-Atabrine dihydrochloride is a less active enantiomer of quinacrine. |