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5

抑制剂 & 化合物

27

天然产物

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Cat. No. Product Name Target Signaling Pathways
T32659 Lettucenin A

Lettucenin A is a sesquiterpenoid lactone phytoalexin.
T12709 Resveratrol analog 2

Others Others
Resveratrol analog 2 is an analog of Resveratrol. Resveratrol is a natural polyphenolic phytoalexin with possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties.
T12708 Resveratrol analog 1

Others Others
Resveratrol analog 1 is an analog of Resveratrol. Resveratrol is a natural polyphenolic phytoalexin with possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties.
T75653 (±)-Columbianetin

Dihydrooroselol

Columbianetin,一种与芹菜贮藏过程中病原体抗性相关的植物抗毒素,展现出优良的抗真菌和抗炎活性。
T36170 A1-Phytoprostane-I

A1-Phytoprostane-I

A1-Phytoprostane-I is a cyclopentenone isoprostane produced by the action of reactive oxygen species on α-linolenic acid in plants. There are two A1-phytoprostanes, both having the single ketone group on the ring structure. This isoform results from cyclization between carbons 9 and 13 of linolenic acid, as opposed to carbons 3 and 7 in A1-phytoprostane-II. A1-Phytoprostanes induce the expression of glutathione-S-transferase, increase phytoalexin biosynthesis, and trigger the expression of sever...

化合物

Lettucenin A
Cat.No: T32659
Synonym:
Target:
Resveratrol analog 2
Cat.No: T12709
Synonym:
Target: Others
Resveratrol analog 1
Cat.No: T12708
Synonym:
Target: Others
(±)-Columbianetin
Cat.No: T75653
Synonym: Dihydrooroselol
Target:
A1-Phytoprostane-I
Cat.No: T36170
Synonym: A1-Phytoprostane-I
Target:
Cat. No. Product Name Target Signaling Pathways
T10668 Camalexin

Reactive Oxygen Species; ROS; Antibacterial; Antifungal Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
Camalexin 是从Camelina sativa 和Arabidopsis 中分离出来的一种植物抗毒素,可诱导活性氧的产生,具有抗菌、抗真菌、抗增殖和抗癌活性。
TN1474 Caulilexin C

板蓝根,1-甲氧基-3-吲哚乙腈

Others; Antifungal Microbiology/Virology; Others
Caulilexin C 是一种来自十字花科植物的植物抗毒素,具有抗真菌活性。
T4373 Brassinin

BSN,芸苔宁

Antifungal Microbiology/Virology
Brassinin (BSN) 是一种从 B. campestris 中分离出来的植物抗毒素,具有抗癌、化学预防、抗增殖和抗真菌活性。
T1693 Umbelliferone

Skimmetine,Hydrangin,Hydrangine,7-羟基香豆素,7-Hydroxycoumarin,NSC 19790

Apoptosis; Antioxidant; Endogenous Metabolite Apoptosis; Metabolism; oxidation-reduction
Umbelliferone (7-Hydroxycoumarin) 是香豆素家族的天然荧光化合物,可用作防晒剂。
TN1126 Sakuranetin

VEGFR; NF-κB; PPAR; Antifungal Angiogenesis; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; NF-κB; Tyrosine Kinase/Adaptors
Sakuranetin 是一种大米黄酮类植物抗毒素,能改善 LPS 诱导的急性肺损伤,具有抗炎、抗真菌和抗氧化作用。
T5S1286 (+)-Columbianetin

二氢山芹醇,(S)-Columbianetin,Columbianetin

Antifungal Microbiology/Virology
(+)-Columbianetin ((S)-Columbianetin) 是 Columbianetin 的异构体。其中Columbianetin 是一种植物抗毒素,与芹菜贮藏过程中对病原体的抗性有关,具有良好的抗真菌和抗炎作用。
TN1918 Medicarpin

美迪紫檀素

Apoptosis; BCL; ROS; JNK Apoptosis; Immunology/Inflammation; MAPK
Medicarpin 是从紫花苜蓿中分离出的一种类黄酮。它通过调节 P-gp 介导的药物外流,诱导白血病 P388 细胞凋亡并克服多药耐药性。
TN3861 Dihydropinosylvin

山药

Anti-infection Microbiology/Virology
Dihydropinosylvin 是一种植物抗毒素,对枝孢枝孢菌、Botryodiplodia theobromae、黑曲霉和石化青霉具有抗真菌活性,对蜡状芽孢杆菌、金黄色葡萄球菌、铜绿假单胞菌和大肠杆菌也有很强的抗菌活性。双色高粱幼苗的种子和根伸长。
TN4509 Medicarpin 3-O-glucoside

Others Others
Medicarpin-3-O-glucoside, a phytoalexin, inhibits the germination of G. intraradices spores and hyphal elongation.
TN5480 (-)-Sativan

(-)-Sativan is a phytoalexin.
TN4310 Isomedicarpin

Others Others
Isomedicarpin is a phytoalexin.
TN4800 Pisatin

NADPH-oxidase; P450 Immunology/Inflammation; Metabolism
Pisatin is an isoflavonoid phytoalexin synthesized by pea (Pisum sativum L.).
TN2912 3,9-Dihydroxypterocarpan

Others Others
3,9-Dihydroxypterocarpan and phaseollidin are all good precursors of the pterocarpan phytoalexin phaseollin.
T21262 Phaseollidin

Phaseollidin, an antimicrobial phytoalexin, is produced by Phaseolus vulgaris (French bean).
TN4760 Phaseollidin hydrate

Antifection Microbiology/Virology
Phaseollidin hydrate shows less antifungal activity than the original phytoalexin phaseollidin.
TN3102 5-Acetyl-6-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran

Others Others
5-Acetyl-6-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran is a phytoalexin.
TN5680 Eriobofuran

Eriobofuran, a phytoalexin, has antimicrobialactivity, it can inhibit strongly the spore germination and germ tube growth of Pestalotia funerea, a host-pathogenic fungus of loquat tree.
TN3346 Actinidic acid

Others Others
Actinidic acid is a triterpene phytoalexin from unripe kiwi fruit.
TN3101 5-Acetyl-2-(1-hydroxy-1-methylethyl)benzofuran

Others Others
5-Acetyl-2-(1-hydroxy-1-methylethyl)benzofuran is a phytoalexin.
T5527 Anigorufone

Antifection Microbiology/Virology
Anigorufone is a phytoalexin, it shows striking antinematode activity. Anigorufone has shown inhibitory activity on the growth of the germinative tube of Fusarium oxysporum f. sp. cubense race 4.
TN2686 2,3,24-Trihydroxyolean-12-en-28-oic acid

Antifection Microbiology/Virology
2α,3α,24-Trihydroxyolean-12-en-28-oic acid, a triterpenoid phytoalexin, isolated from peel of unripe fruits of nectarine (Prunus persica cv Fantasia), shows antifungal activity against the fungus mentioned.
TN3035 4'-Hydroxy-2-O-methylanigorufone

Others Others
9-(4'-Hydroxyphenyl)-2-methoxyphenalen-1-one(4'-Hydroxy-2-O-methylanigorufone) is a phytoalexin. It shows a strong α-glucosidase inhibitory effect.
T81653 Noraucuparin

Noraucuparin是从Sorbus pohuashanensis的叶子中分离得到的联苯型植物抗毒素,具有抗真菌作用。
TN2685 2,3,24-Trihydroxy-12-ursen-28-oic acid

Antifection Microbiology/Virology
2α,3α,24-Trihydroxyurs-12-en-28-oic acid, a triterpenoid phytoalexin, shows antifungal activity against the fungus mentioned. It also shows in vitro cytotoxic activity against tumor cell lines including PLC,Hep3B,HepG2,HeLa,SW480,MCF-7 and Bel7402.
TN2736 2',6'-Dihydroxy-4'-methoxyacetophenone

Antifection Microbiology/Virology
2',6'-Dihydroxy-4'-methoxyacetophenone is a phytoalexin after fungal inoculation with Botrytis cinerea or UV light irradiation, it has spore germination inhibition on Botrytis cinerea and Phomopsis perniciosa, with ED50 values of 45 and 410 uM, respective
TN5228 Vestitol

Antifection Microbiology/Virology
Vestitol is a phytoalexin with insect feeding-deterrent activity, it has antioxidant, anti-inflammatory and antimicrobial activities, it can inhibit neutrophil migration at a dose of 10 mg/kg, and shows MICs ranging from 25-50 to 50-100 ug/mL and MBCs ranging from 25-50 to 50-100 ug/mL.Vestitol exerts a limited inhibitory effect on S. hermonthica germination, it can significantly inhibit seedling growth, it also contributes, at least in part, to the host's defence mechanism and acts as a chemica...
T36348 Cerebroside C

Cerebroside C is a fungal metabolite and glycosphingolipid that has been found in the rice pathogenic fungusM. grisea.1It induces production of the phytoalexin momilactone A when applied to wounded rice leaves, indicating that cerebroside C is an elicitor of the hypersensitive response in rice. Cerebroside C increases germination rate and reduces germination time in wheat seeds in a concentration-dependent manner at 4°C.2It also increases root length, fresh weight, and dry weight of wheat seedli...

天然产物

Camalexin
Cat.No: T10668
Synonym:
Target: Reactive Oxygen Species, ROS, Antibacterial, Antifungal
Caulilexin C
Cat.No: TN1474
Synonym: 板蓝根,1-甲氧基-3-吲哚乙腈
Target: Others, Antifungal
Brassinin
Cat.No: T4373
Synonym: BSN,芸苔宁
Target: Antifungal
Umbelliferone
Cat.No: T1693
Synonym: Skimmetine,Hydrangin,Hydrangine,7-羟基香豆素,7-Hydroxycoumarin,NSC 19790
Target: Apoptosis, Antioxidant, Endogenous Metabolite
Sakuranetin
Cat.No: TN1126
Synonym:
Target: VEGFR, NF-κB, PPAR, Antifungal
(+)-Columbianetin
Cat.No: T5S1286
Synonym: 二氢山芹醇,(S)-Columbianetin,Columbianetin
Target: Antifungal
Medicarpin
Cat.No: TN1918
Synonym: 美迪紫檀素
Target: Apoptosis, BCL, ROS, JNK
Dihydropinosylvin
Cat.No: TN3861
Synonym: 山药
Target: Anti-infection
Medicarpin 3-O-glucoside
Cat.No: TN4509
Synonym:
Target: Others
(-)-Sativan
Cat.No: TN5480
Synonym:
Target:
Isomedicarpin
Cat.No: TN4310
Synonym:
Target: Others
Pisatin
Cat.No: TN4800
Synonym:
Target: NADPH-oxidase, P450
3,9-Dihydroxypterocarpan
Cat.No: TN2912
Synonym:
Target: Others
Phaseollidin
Cat.No: T21262
Synonym:
Target:
Phaseollidin hydrate
Cat.No: TN4760
Synonym:
Target: Antifection
5-Acetyl-6-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran
Cat.No: TN3102
Synonym:
Target: Others
Eriobofuran
Cat.No: TN5680
Synonym:
Target:
Actinidic acid
Cat.No: TN3346
Synonym:
Target: Others
5-Acetyl-2-(1-hydroxy-1-methylethyl)benzofuran
Cat.No: TN3101
Synonym:
Target: Others
Anigorufone
Cat.No: T5527
Synonym:
Target: Antifection
2,3,24-Trihydroxyolean-12-en-28-oic acid
Cat.No: TN2686
Synonym:
Target: Antifection
4'-Hydroxy-2-O-methylanigorufone
Cat.No: TN3035
Synonym:
Target: Others
Noraucuparin
Cat.No: T81653
Synonym:
Target:
2,3,24-Trihydroxy-12-ursen-28-oic acid
Cat.No: TN2685
Synonym:
Target: Antifection
2',6'-Dihydroxy-4'-methoxyacetophenone
Cat.No: TN2736
Synonym:
Target: Antifection
Vestitol
Cat.No: TN5228
Synonym:
Target: Antifection
Cerebroside C
Cat.No: T36348
Synonym:
Target:
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