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21

抑制剂 & 化合物

5

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T33565	NAAD sodium salt NAAD钠盐,NAAD Na salt,Deamido Nad Sodium Salt,NAAD Na, NaAD
	NAAD sodium salt (NAAD Na salt) 是烟酰胺腺嘌呤二核苷酸合酶的底物，可用于研究底物的特异性和动力学。
TF0112	DPPS 12-Dipalmitoyl-sn-glycero-3-PS sodium salt,DPPS-Na	Others	Others
	DPPS (12-Dipalmitoyl-sn-glycero-3-PS sodium salt) 是一种阴离子二酰基磷脂，是磷脂酰丝氨酸(PS)的一种形式，是一种位于细胞膜内小叶的带负电荷的磷脂。DPPS 被用来制作阳离子囊泡和脂质体。
T4535	Etomoxir sodium salt (R)-(+)-乙莫克舍钠盐,(R)-Etomoxir sodium salt,Na salt,Etomoxir	Apoptosis; Others	Apoptosis; Others
	Etomoxir sodium salt ((R)-Etomoxir sodium salt) 是一种肉碱棕榈酰转移酶 1a (CPT-1a) 抑制剂，可以阻断脂肪酸合成。Etomoxir sodium salt 具有抗肿瘤活性。
T19820	MOPS sodium salt MOPS-Na,3-(N-morpholino)propanesulfonic acid sodium salt,3-吗啉丙磺酸钠盐,Sodium 3-Morpholinopropanesulfonate,4-Morpholinepropanesulfonic acid, sodium salt	Others	Others
	MOPS sodium salt (MOPS-Na) 在生物学中常用作缓冲剂。其中MOPS 缓冲液能使哺乳动物细胞培养基的 pH 值保持稳定。
T0917	Sulfaquinoxaline sodium salt SQ-Na,磺胺喹恶啉钠盐,Sulfaquinoxaline sodium,磺胺喹啉钠	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Sulfaquinoxaline sodium salt (SQ-Na) 是一种兽用广谱抗菌剂，有抗革兰氏阴性菌和革兰氏阳性菌活性。Sulfaquinoxaline 能用于预防球虫病和细菌感染。
T0008	Phenytoin sodium 5,5-Diphenylhydantoin sodium salt,Diphantoine,苯妥英钠,Dilantin sodium,Diphenylhydantoin Sodium	Virus Protease; Sodium Channel	Membrane transporter/Ion channel; Microbiology/Virology
	Phenytoin sodium (Diphantoine) 是一种有效的电压门控钠离子通道阻滞剂，可减少小鼠乳腺肿瘤的生长和转移，具有抗癫痫活性。
T25968	PMPA sodium PMPA sodium salt,PMPA tetrasodium salt,PMPA Na
	PMPA sodium is a potent and selective glutamate carboxypeptidase 2 (GCP II/N-acetylated a-linked dipeptidase/NAALADase) inhibitor.
T25953	PHPS1 Sodium PHPS1 Na,PHPS1 Sodium salt
	PHPS1 sodium 是 Shp2的选择性抑制剂，对 Shp2，Shp2-R362K，Shp1，PTP1B 和 PTP1B-Q 的Ki 值分别为 0.73，5.8，10.7，5.8 和 0.47 μM。
T31077	CP-74725, sodium salt UNII-0O56W95D3P,CP-74725 salt,CP-74725, Na+ salt
	CP-74725, sodium salt is a bio-active chemical.
T69817	Eprociclovir Na
	Eprociclovir Na is the salt form of Eprociclovir, also known as A-5021, a new acyclovir analogue and a potent inhibitor of EHV1 replication and may have potential for the treatment and/or prophylaxis of infections with this virus. Eprociclovir possess potent anti-herpetic activity against most human herpesviruses. A-5021 proved to be about 15-fold more potent than acyclovir in inhibiting viral replication. Eprociclovir inhibits murine herpetic keratitis. A-5021 eyedrops, which are easily applie...
T68357	Nelonemdaz Na
	Nelonemdaz Na is a NMDA receptor antagonist potentially for the treatment of stroke.
T71213	Amesergide
	Amesergide is a serotonin antagonist.
T3290L	Pikamilone Sodium GABA-NG,Nicotinoyl-GABA sodium salt,GABA NG,GABANG,Pikamilone Na
	Pikamilone Sodium is a prodrug of GABA used for therapy of neurogenic bladder in spinal and benign prostatic hyperplasia.
T67073	1,2-Distearoyl-sn-glycero-3-phosphatidic acid (Na+ salt)
	1,2-Distearoyl-sn-glycero-3-phosphatidic acid (Na+ salt) 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T67073。
T0941	Cyclamic acid Cyclamate,NSC 220327,Cyclohexylsulfamic acid,环己基氨基磺酸,环拉酸	Others	Others
	Cyclamic acid (NSC-220327) 是食品和药品中应用最广泛的一种人造甜味剂。
T1666	Fludrocortisone acetate 9α-Fluorcortisol acetate,9α-Fludrocortisone acetate,醋酸氟氢可的松,9α-fluorocortisol acetate	Glucocorticoid Receptor; Autophagy	Autophagy; Endocrinology/Hormones
	Fludrocortisone acetate (9α-Fludrocortisone acetate) 是一种合成的盐皮质激素，可减少尿液中钠丢失量，也用于增加血压，有用于阿狄森氏病的研究潜力。
T71042	Kijimicin Na
	Kijimicin Na is the salt form of Kijimicin Free Base, a polyether antibiotic and inhibitor of human immunodeficiency virus in acutely and chronically infected cells.
T36482	Lamotrigine isethionate
	Water-soluble salt of lamotrigine . Displays anticonvulsant effects and inhibits glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents. Leach et al (1991) Neurochemical and behavioral aspects of lamotr. Epilepsia 32 S4 PMID:1685439 \|Smith and Meldrum (1995) Cardioprotective effect of lamotr. after focal ischemia in rats. Stroke 26 117 PMID:7839380 \|Zona and Avoli (1997) Lamotrigine reduces voltage-gated sodium currents in rat central neurons in culture. Epilepsia 38 522 PMI...
T70975	Carsatrin succinate
	Carsatrin succinate is the salt form of Carsatin, a purinylpiperazine derivative used as a cardiotonic and antiarrhythmic. Carsatrin acts as positive inotropic agent that increases twitch tension and prolongs the action potential (AP) duration of ventricular muscle without affecting the Na+, K+-ATPase, adenylyl cyclase, phosphodiesterase isozymes, or cardiac myofilaments. Carsatrin’s positive inotropic effect can be prevented by tetrodotoxin but not by the adrenergic antagonists timolol, yohimbi...
T70428	Nepaprazole sodium
	Nepaprazole Na is the salt form of Nepaprazole Free Base, also known as TY-11345, is a proton pump inhibitor potentially for treatment of gastric ulcer. TY-11345 potently inhibited H+/K(+)-ATPase activity in isolated rabbit gastric mucosal microsomes; and the inhibitory effect was enhanced under weak acid conditions, the IC50 (concentrations that inhibit the enzyme activity by 50%) being 5.8 microM and 9.9 microM at pH 6.0 and pH 7.4, respectively. TY-11345 should be useful for the clinical tre...
T35876	Chlorthalidone Impurity G
	Chlorthalidone impurity G is a potential impurity found in commercial preparations of chlorthalidone that has moderate antihypertensive effects. Chlorthalidone is a thiazide-like diuretic that inhibits the Na+/Cl- cotransporter in the distal convoluted tubule of the kidney, which prevents reabsorption of sodium and chloride leading to a reduction in plasma volume and cardiac output. It also inhibits carbonic anhydrase (CA), including the isoforms CAVB, VII, IX, XII, and XIII (Kis = 2.8-23 nM) an...

化合物

NAAD sodium salt

Cat.No: T33565

Synonym: NAAD钠盐,NAAD Na salt,Deamido Nad Sodium Salt,NAAD Na, NaAD

Cat.No: TF0112

Synonym: 12-Dipalmitoyl-sn-glycero-3-PS sodium salt,DPPS-Na

Target: Others

Etomoxir sodium salt

Cat.No: T4535

Synonym: (R)-(+)-乙莫克舍钠盐,(R)-Etomoxir sodium salt,Na salt,Etomoxir

Target: Apoptosis, Others

MOPS sodium salt

Cat.No: T19820

Synonym: MOPS-Na,3-(N-morpholino)propanesulfonic acid sodium salt,3-吗啉丙磺酸钠盐,Sodium 3-Morpholinopropanesulfonate,4-Morpholinepropanesulfonic acid, sodium salt

Target: Others

Sulfaquinoxaline sodium salt

Cat.No: T0917

Synonym: SQ-Na,磺胺喹恶啉钠盐,Sulfaquinoxaline sodium,磺胺喹啉钠

Target: Antibacterial, Antibiotic, Parasite

Phenytoin sodium

Cat.No: T0008

Synonym: 5,5-Diphenylhydantoin sodium salt,Diphantoine,苯妥英钠,Dilantin sodium,Diphenylhydantoin Sodium

Target: Virus Protease, Sodium Channel

Cat.No: T25968

Synonym: PMPA sodium salt,PMPA tetrasodium salt,PMPA Na

Cat.No: T25953

Synonym: PHPS1 Na,PHPS1 Sodium salt

CP-74725, sodium salt

Cat.No: T31077

Synonym: UNII-0O56W95D3P,CP-74725 salt,CP-74725, Na+ salt

Eprociclovir Na

Cat.No: T69817

Cat.No: T68357

Cat.No: T71213

Pikamilone Sodium

Cat.No: T3290L

Synonym: GABA-NG,Nicotinoyl-GABA sodium salt,GABA NG,GABANG,Pikamilone Na

1,2-Distearoyl-sn-glycero-3-phosphatidic acid (Na+ salt)

Cat.No: T67073

Cat.No: T0941

Synonym: Cyclamate,NSC 220327,Cyclohexylsulfamic acid,环己基氨基磺酸,环拉酸

Target: Others

Fludrocortisone acetate

Cat.No: T1666

Synonym: 9α-Fluorcortisol acetate,9α-Fludrocortisone acetate,醋酸氟氢可的松,9α-fluorocortisol acetate

Target: Glucocorticoid Receptor, Autophagy

Cat.No: T71042

Lamotrigine isethionate

Cat.No: T36482

Carsatrin succinate

Cat.No: T70975

Nepaprazole sodium

Cat.No: T70428

Chlorthalidone Impurity G

Cat.No: T35876

Cat. No.	Product Name	Target	Signaling Pathways
TN7245	DMPS-Na 1,2-Dimyristoyl-sn-glycero-3-phosphoserine sodium salt	Others	Others
	DMPS-Na 是一种带有毒性的解砷灵，可用于研究细胞膜。
T1033	Monensin sodium salt 莫能菌素钠盐,Sodium Monensin,Monensin A sodium salt	Sodium Channel; Antibacterial; Antibiotic	Membrane transporter/Ion channel; Microbiology/Virology
	Monensin sodium salt (Monensin A sodium salt) 是由肉桂链霉菌分泌的抗生素。它是一种介导Na+/H+交换的离子载体。它引起细胞多泡体 (MVBs) 增大并调节外泌体的分泌。
T1331	Riboflavin phosphate sodium Riboflavin 5'-phosphate sodium,核黄素磷酸钠(维生素B2),Vitamin B2 Phosphate Sodium Salt,Flavin mononucleotide,FMN,核黄素磷酸钠,FMN-Na,riboflavin-5'-phosphate	Endogenous Metabolite	Metabolism
	Riboflavin phosphate sodium (FMN) 是 riboflavin 的磷酸钠盐形式，riboflavin 是一种水溶性和必需的微量营养素，是自然产生的维生素B复合物的主要生长促进因子。Riboflavin phosphate sodium 转化为2种辅酶，黄素单核苷酸(FMN)和黄素腺嘌呤二核苷酸(FAD)，这两种辅酶通过帮助脂肪、碳水化合物和蛋白质的代谢来产生能量，并且是红细胞形成和呼吸、抗体产生以及调节人体生长和繁殖所必需的。
T29078	Ursodeoxycholic acid sodium UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,熊去氧胆酸钠盐,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium	FXR; Endogenous Metabolite; GPCR19	GPCR/G Protein; Metabolism
	Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) 是一种天然存在的次级胆汁酸，具有抗炎和细胞保护活性。Ursodeoxycholic acid sodium 作为信号分子，通过与胆汁酸激活受体相互作用发挥其作用，包括 G 蛋白偶联胆汁酸受体 5 (TGR5) 和法尼醇 X 受体 (FXR)。
T36390	Sodium oleate Oleic acid sodium salt,Sodium oleate,cis-9-Octadecenoic acid sodium salt	ATPase	Membrane transporter/Ion channel
	Sodium oleate (cis-9-Octadecenoic acid sodium salt) (Oleic acid sodium) 是人脂肪细胞和其他组织中最常见的单不饱和脂肪酸钠盐。Sodium oleate 是一种 Na+/K+ ATP 酶激活剂。

天然产物

Cat.No: TN7245

Synonym: 1,2-Dimyristoyl-sn-glycero-3-phosphoserine sodium salt

Target: Others

Monensin sodium salt

Cat.No: T1033

Synonym: 莫能菌素钠盐,Sodium Monensin,Monensin A sodium salt

Target: Sodium Channel, Antibacterial, Antibiotic

Riboflavin phosphate sodium

Cat.No: T1331

Synonym: Riboflavin 5'-phosphate sodium,核黄素磷酸钠(维生素B2),Vitamin B2 Phosphate Sodium Salt,Flavin mononucleotide,FMN,核黄素磷酸钠,FMN-Na,riboflavin-5'-phosphate

Target: Endogenous Metabolite

Ursodeoxycholic acid sodium

Cat.No: T29078

Synonym: UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,熊去氧胆酸钠盐,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium

Target: FXR, Endogenous Metabolite, GPCR19

Cat.No: T36390

Synonym: Oleic acid sodium salt,Sodium oleate,cis-9-Octadecenoic acid sodium salt

Target: ATPase

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