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37

抑制剂 & 化合物

8

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T64329	Fmoc-L-glutamic acid 5-tert-butyl ester Fmoc-Glu(OtBu)-OH	Amino Acids and Derivatives	Metabolism
	Fmoc-L-glutamic acid 5-tert-butyl ester (Fmoc-Glu(OtBu)-OH) 是一种谷氨酸衍生物。
T33868	Palmitoyl glutamic acid N-Palmitoyl-L-glutamic acid,Palmitoylglutaminic acid
	Palmitoyl glutamic acid (N-Palmitoyl-L-glutamic acid) 是一种酰基氨基酸，可阻断主动脉收缩,可拮抗由氟哌啶醇诱发的口腔运动障碍。Palmitoyl glutamic acid 常常添加在化妆品中。
T20330	Lauroyl glutamic acid N-Lauroyl-L-glutamic acid,N-月桂酰-L-谷氨酸	Others	Others
	Lauroyl glutamic acid (N-Lauroyl-L-glutamic acid) 具有平喘作用。
T20362	Glutamyl-glutamic acid Glu-glu,Dipotassium glutamyl-glutamate,N-L-alpha-Glutamyl-L-glutamic acid	Amino Acids and Derivatives	Metabolism
	Glutamyl-glutamic acid (Glu-glu) 是一些微球菌和节杆菌属菌的胞壁中的肽桥。
T67579	H-Glu(OMe)-OH L-Glutamic acid 5-methyl ester	Amino Acids and Derivatives	Metabolism
	H-Glu(OMe)-OH 是一种谷氨酸衍生物，可用于合成多种化合物且与机体免疫和代谢有关。
T0755	Carglumic Acid Carbaglu,N-Carbamylglutamate,N-Carbamyl-L-glutamic acid,氨甲酰谷氨酸,Carbamylglutamic acid,Carbamino-L-glutamic acid,Ureidoglutaric acid	Others	Others
	Carglumic Acid (Ureidoglutaric acid) 是一种 N-乙酰谷氨酸 (NAG) 的功能类似物和氨甲酰磷酸合成酶 1(CPS1)的活化剂，可用于与 N-乙酰谷氨酸合成酶 (NAGS) 缺陷相关的急性和慢性高氨血症的研究。
T39565	L-Glutamic acid-15N
	L-Glutamic acid-15N is the 15N-labeled version of L-Glutamic acid, an excitatory neurotransmitter and an agonist at metabotropic, kainate, NMDA, and AMPA glutamate receptor subtypes. It directly activates the release of dopamine (DA) from dopaminergic terminals.
T32734	L-Glutamic-5-14C acid (1-14C)Glutamic acid
	L-Glutamic-5-14C acid is a bioactive chemical.
T19301	DUPA N,N''-Carbonylbis[L-glutamic acid],(2S,2'S)-2,2'-Carbonylbis(Azanediyl)Dipentanedioic Acid	Others; Ligands for Target Protein for PROTAC	Others; PROTAC
	DUPA (N,N''-Carbonylbis[L-glutamic acid]) 是谷氨酸脲，在药物偶联中作为靶向部分，可选择靶向性地将细胞毒性药物递送到前列腺癌细胞。
T37998	N-(4-Aminobenzoyl)-L-glutamic Acid (hydrate)
	N-(4-Aminobenzoyl)-L-glutamic acid is an oxidation product and a metabolite of tetrahydrofolate.1Levels of N-(4-aminobenzoyl)-L-glutamic acid are increased in the plasma of mice fed a high folic acid-containing diet.2 1.Reed, L.S., and Archer, M.C.Oxidation of tetrahydrofolic acid by airJ. Agric. Food Chem.28(4)801-805(1980) 2.Burton, M.A., Antoun, E., Penailillo, R.S., et al.Folic acid induces intake-related changes in the mammary tissue transcriptome of C57BL/6 miceNutrients12(9)2821(2020)
T32733	L-Glutamic acid, N-nicotinoyl-, disodium salt L-Glutamic acid, N-(3-pyridinylcarbonyl)-, disodium salt,N-(3-Pyridinylcarbonyl)glutamine disodium salt
	L-Glutamic acid, N-(3-pyridinylcarbonyl)-, disodium salt is a bioactive chemical.
T33540	Myristoyl glutamic acid N-Myristoyl-L-glutamic acid,N-Tetradecanoyl-L-glutamic acid,Glutamic acid, N-myristoyl-, l-	Antibacterial	Microbiology/Virology
	Myristoyl glutamic acid （N-Myristoyl-L-glutamic acid）是一种肉豆蔻酰谷氨酸，是一种可添加进化好妆品中的表面活性剂，具有发泡和部分抑菌活性。
T31943	Glutamic acid, N-stearoyl- N-Stearoyl-L-glutamic acid,Acide stearoylglutaminique,Stearoyl glutamic acid
	Glutamic acid, N-stearoyl- is a α-amino acid.
T31518	Dipinacoline glutamate L-Glutamic acid dipinacoline ester,DiPG
	Dipinacoline glutamate is a bioactive chemical.
T20264	Ala-Glu-OH L-Glutamic acid, N-L-alanyl-,Alanine glutamate,Alanylglutamic acid
	Alanine glutamate is an agent of the dipeptide.
T31497	Dineopentyl glutamate L-Glutamic acid bis(2,2-dimethylpropyl) ester,DNPE
	Dineopentyl glutamate is a bioactive chemical.
T34676	Sodium oleoyl glutamate N-Oleoyl-L-glutamic acid monosodium salt,Acylglutamate OS-11
	Sodium oleoyl glutamate is a sodium salt oleoyl glutamate.
T30691	Calcium diglutamate Calcium di-L-glutamate,Glutamic acid, calcium salt (2:1), L-
	Calcium diglutamate(CDG), calcium acid salt of glutamic acid. As a soluble source of calcium ions, this chemical is used as a first-aid treatment for exposure to hydrofluoric acid.
T33691	Nitrosofolic acid CCRIS 466,N-Nitrosofolic acid,Glutamic acid, N-nitroso-N-pteroyl-, L-
	Nitrosofolic acid is a folic acid derivaive.
T35369	L(+)-Monosodium glutamate monohydrate L(+)-Monosodium glutamate monohydrate,MSG monohydrate,L-Glutamic acid monosodium salt monohydrate,Monosodium L-glutamate monohydrate	Others	Others
	L(+)-Monosodium glutamate monohydrate (MSG monohydrate, L-Glutamic acid monosodium salt monohydrate, Monosodium L-glutamate monohydrate, Monosodium L-glutamate monohydrate)是一种广泛使用的营养添加剂和调味剂。L(+)-Monosodium glutamate monohydrate 可导致氧化应激介导的 DNA 损伤和细胞凋亡。
T33731	N-Phthaloylglutamic acid alpha-N-Phthaloylglutamic acid,N,N-Phthaloyl-L-glutamic acid,PhGA
	N-Phthaloylglutamic acid is a hydrolytic metabolite of thalidomide.
T24535	Ninopterin NSC-107137,NSC107137,9-Me-PGA,NSC 107137,L-Glutamic acid, 9-methylpteroyl-
	Ninopterin is an experimental antineoplastic and folic acid analog.
T2A2497L	Glutamic acid diethyl ester L-Glutamate diethylester,Diethyl glutamate,Glutamyl diethyl ester
	Glutamic acid diethyl ester is a glutamic acid antagonist.
T60243	Glycyl-L-glutamic acid
	Glycyl-L-glutamic acid 是一种体内神经营养因子 (NF)，发挥维持 AChE 含量和活性的作用。Glycyl-L-glutamic acid 不直接作用于 AChE 的合成，可能具有防止神经节前神经元退变的作用。
T15391	Glufosinate ammonium	Others	Others
	Glufosinate ammonium 是谷氨酸的一种膦酸类似物，是一种除草剂，在植物细胞中转化为 PT (L-phosphinothricin) 。Glufosinate ammonium 显示出神经毒性作用。
TP1079	(Arg)9 TFA (143413-47-2 free base) Nona-L-arginine (TFA),(Arg)9 TFA,Peptide R9 (TFA)	Others	Others
	(Arg)9 TFA (Peptide R9 TFA) 是一种可渗透细胞的多肽，在谷氨酸模型实验模型中保护神经(IC50:0.78 μM)。
T37190	L-Allylglycine	Dehydrogenase; GABA Receptor	Membrane transporter/Ion channel; Metabolism; Neuroscience
	L-Allylglycine 是 GABA 合成酶（谷氨酸脱羧酶）的有效抑制剂。
T15391L	Glufosinate	Others	Others
	Glufosinate, a phosphinic acid analog of glutamic acid, is a herbicide that is converted by plant cells into PT (L-phosphinothricin). It has neurotoxic activity.
T81914	L-Pyroglutamic acid β-naphthylamide PYR
	L-Pyroglutamic acid β-naphthylamide (PYR) 是一谷氨酸衍生物。
T31263	Deanol aceglumate Otrun,Deanolo aceglumato,Risatarun,Deanoli aceglumas
	Deanol aceglumate is combination of deanol and N-acetyl-L-glutamic acid. deanol aceglumate can effect Hepatoprotective on stress-induced gastropathy and diabetes mellitus.
T60112	H-Glu(OEt)-OEt.HCl Diethyl L-glutamate hydrochloride,(S)-Diethyl 2-aminopentanedioate hydrochloride,L-谷氨酸二乙酯盐酸盐,Diethyl glutamate hydrochloride	Amino Acids and Derivatives	Metabolism
	H-Glu(OEt)-OEt.HCl (Diethyl L-glutamate hydrochloride) 是一种谷氨酸衍生物。
T13976	(Arg)9 Peptide R9,Nona-L-arginine	Others	Others
	(Arg)9 (Nona-L-arginine;Peptide R9) is a cell-penetrating peptide,and exhibits neuroprotective activity(IC50 of 0.78 μM, in the glutamic acid model).
T16800	(RS)-AMPA (±)-AMPA	iGluR	Membrane transporter/Ion channel; Neuroscience
	(RS)-AMPA ((±)-AMPA) 是谷氨酸的一种类似物，对兴奋性神经递质 L-谷氨酸有激动作用。它不会干扰海藻酸或 NMDA 受体的结合位点。
T60242	(RS)-AMPA monohydrate
	(RS)-AMPA ((±)-AMPA) monohydrate 是谷氨酸的一种类似物，对兴奋性神经递质 L-谷氨酸 (L-glutamic acid) 有激动作用。(RS)-AMPA monohydrate 不会干扰海藻酸或 NMDA 受体的结合位点。
T77998	(Arg)9 acetate Peptide R9 acetate,Nona-L-arginine acetate
	(Arg)9 (Nona-L-arginine) acetate 是一种细胞穿透肽(CPP)，由9个L-精氨酸残基构成，显示出神经保护作用，其在谷氨酸模型中的IC50值为0.78 μM。
T71180	Oglufanide disodium
	Oglufanide disodium is t he disodium salt of a synthetic form of a naturally-occurring dipeptide consisting of L-glutamic acid and L-tryptophan with potential antiangiogenic and potential immunomodulating activities. Oglufanide inhibits vascular endothelial growth factor (VEGF), which may inhibit angiogenesis. This agent has also been reported to stimulate the immune response to hepatitic C virus and intracellular bacterial infections. Check for active clinical trials or closed clinical trials u...
T22509	3-Methyl-GABA	Others	Others
	3-Methyl-GABA 是一种有效的GABA 氨基转移酶激活剂。3-Methyl-GABA 能与 GABAA 受体 (GABAaR) 结合。3-Methyl-GABA 能够激活 L-谷氨酸脱羧酶 (GAD)，表现出抗惊厥作用。

化合物

Fmoc-L-glutamic acid 5-tert-butyl ester

Cat.No: T64329

Synonym: Fmoc-Glu(OtBu)-OH

Target: Amino Acids and Derivatives

Palmitoyl glutamic acid

Cat.No: T33868

Synonym: N-Palmitoyl-L-glutamic acid,Palmitoylglutaminic acid

Lauroyl glutamic acid

Cat.No: T20330

Synonym: N-Lauroyl-L-glutamic acid,N-月桂酰-L-谷氨酸

Target: Others

Glutamyl-glutamic acid

Cat.No: T20362

Synonym: Glu-glu,Dipotassium glutamyl-glutamate,N-L-alpha-Glutamyl-L-glutamic acid

Target: Amino Acids and Derivatives

Cat.No: T67579

Synonym: L-Glutamic acid 5-methyl ester

Target: Amino Acids and Derivatives

Carglumic Acid

Cat.No: T0755

Synonym: Carbaglu,N-Carbamylglutamate,N-Carbamyl-L-glutamic acid,氨甲酰谷氨酸,Carbamylglutamic acid,Carbamino-L-glutamic acid,Ureidoglutaric acid

Target: Others

L-Glutamic acid-15N

Cat.No: T39565

L-Glutamic-5-14C acid

Cat.No: T32734

Synonym: (1-14C)Glutamic acid

Cat.No: T19301

Synonym: N,N''-Carbonylbis[L-glutamic acid],(2S,2'S)-2,2'-Carbonylbis(Azanediyl)Dipentanedioic Acid

Target: Others, Ligands for Target Protein for PROTAC

N-(4-Aminobenzoyl)-L-glutamic Acid (hydrate)

Cat.No: T37998

L-Glutamic acid, N-nicotinoyl-, disodium salt

Cat.No: T32733

Synonym: L-Glutamic acid, N-(3-pyridinylcarbonyl)-, disodium salt,N-(3-Pyridinylcarbonyl)glutamine disodium salt

Myristoyl glutamic acid

Cat.No: T33540

Synonym: N-Myristoyl-L-glutamic acid,N-Tetradecanoyl-L-glutamic acid,Glutamic acid, N-myristoyl-, l-

Target: Antibacterial

Glutamic acid, N-stearoyl-

Cat.No: T31943

Synonym: N-Stearoyl-L-glutamic acid,Acide stearoylglutaminique,Stearoyl glutamic acid

Dipinacoline glutamate

Cat.No: T31518

Synonym: L-Glutamic acid dipinacoline ester,DiPG

Cat.No: T20264

Synonym: L-Glutamic acid, N-L-alanyl-,Alanine glutamate,Alanylglutamic acid

Dineopentyl glutamate

Cat.No: T31497

Synonym: L-Glutamic acid bis(2,2-dimethylpropyl) ester,DNPE

Sodium oleoyl glutamate

Cat.No: T34676

Synonym: N-Oleoyl-L-glutamic acid monosodium salt,Acylglutamate OS-11

Calcium diglutamate

Cat.No: T30691

Synonym: Calcium di-L-glutamate,Glutamic acid, calcium salt (2:1), L-

Nitrosofolic acid

Cat.No: T33691

Synonym: CCRIS 466,N-Nitrosofolic acid,Glutamic acid, N-nitroso-N-pteroyl-, L-

L(+)-Monosodium glutamate monohydrate

Cat.No: T35369

Synonym: L(+)-Monosodium glutamate monohydrate,MSG monohydrate,L-Glutamic acid monosodium salt monohydrate,Monosodium L-glutamate monohydrate

Target: Others

N-Phthaloylglutamic acid

Cat.No: T33731

Synonym: alpha-N-Phthaloylglutamic acid,N,N-Phthaloyl-L-glutamic acid,PhGA

Cat.No: T24535

Synonym: NSC-107137,NSC107137,9-Me-PGA,NSC 107137,L-Glutamic acid, 9-methylpteroyl-

Glutamic acid diethyl ester

Cat.No: T2A2497L

Synonym: L-Glutamate diethylester,Diethyl glutamate,Glutamyl diethyl ester

Glycyl-L-glutamic acid

Cat.No: T60243

Glufosinate ammonium

Cat.No: T15391

Target: Others

(Arg)9 TFA (143413-47-2 free base)

Cat.No: TP1079

Synonym: Nona-L-arginine (TFA),(Arg)9 TFA,Peptide R9 (TFA)

Target: Others

Cat.No: T37190

Target: Dehydrogenase, GABA Receptor

Cat.No: T15391L

Target: Others

L-Pyroglutamic acid β-naphthylamide

Cat.No: T81914

Synonym: PYR

Deanol aceglumate

Cat.No: T31263

Synonym: Otrun,Deanolo aceglumato,Risatarun,Deanoli aceglumas

H-Glu(OEt)-OEt.HCl

Cat.No: T60112

Synonym: Diethyl L-glutamate hydrochloride,(S)-Diethyl 2-aminopentanedioate hydrochloride,L-谷氨酸二乙酯盐酸盐,Diethyl glutamate hydrochloride

Target: Amino Acids and Derivatives

Cat.No: T13976

Synonym: Peptide R9,Nona-L-arginine

Target: Others

Cat.No: T16800

Synonym: (±)-AMPA

Target: iGluR

(RS)-AMPA monohydrate

Cat.No: T60242

Cat.No: T77998

Synonym: Peptide R9 acetate,Nona-L-arginine acetate

Oglufanide disodium

Cat.No: T71180

Cat.No: T22509

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T2A2497	L-Glutamic acid 谷氨酸,(S)-Glutamic acid,glutamic acid,(+)-L-Glutamic acid,Aciglut,L-谷氨酸,glutacid,Glutaminol	Apoptosis; Ferroptosis; Endogenous Metabolite; iGluR	Apoptosis; Membrane transporter/Ion channel; Metabolism; Neuroscience
	L-Glutamic acid (Glutaminol) 作为一种兴奋性氨基酸神经递质，为谷氨酸盐受体所有亚型的激动剂，对多巴胺从神经末梢释放的过程有激动作用。
T6871	L-Glutamic acid monosodium salt Monosodium glutamate,谷氨酸单钠盐,Glutacyl,Glutavene,L-谷氨酸单钠盐,Ajinomoto,MSG	Apoptosis; Ferroptosis; GluR; iGluR	Apoptosis; Membrane transporter/Ion channel; Neuroscience
	L-Glutamic acid monosodium salt (MSG) 作为兴奋性氨基酸神经递质，是谷氨酸盐受体所有亚型的激动剂，对多巴胺从神经末梢释放的过程有激动作用。
T5267	N-Acetyl-L-glutamic acid Ac-L-Glu-OH,N-乙酰-L-谷氨酰胺,N-Acetylglutamic acid	Others; Endogenous Metabolite	Metabolism; Others
	N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) 是一种 N-Acyl-L-氨基酸，是动物细胞培养基的组成成分，是一种酿酒酵母和人类的代谢物。
T0326L	L-Glutamine L-Glutamic acid 5-amide,L-谷氨酰胺	Ferroptosis; Endogenous Metabolite; GluR	Apoptosis; Metabolism; Neuroscience
	L-Glutamine (L-Glutamic acid 5-amide) 是在人体中大量存在的一种非必需氨基酸，由谷氨酸和氨合成。它为某些细胞中的氧化提供了碳源。
T10935	D-Glutamic acid (R)-Glutamic acid,D-谷氨酸	Endogenous Metabolite	Metabolism
	D-Glutamic acid ((R)-Glutamic acid) 是一种广泛用于药物和食品中的L-glutamic acid 对映异构体。
T0507	L-Pyroglutamic acid L-焦谷氨酸,pidolic acid,L-pyroglutamate,5-Oxoproline	Others; Endogenous Metabolite	Metabolism; Others
	L-Pyroglutamic acid (pidolic acid) 是 Pyroglutamic acid 的左旋异构体，是人体中具有生物特性的对映异构体。Pyroglutamic acid 是谷胱甘肽代谢中的中间体。
T4901	5'-Guanylic acid disodium salt Guanosine 5'-monophosphate disodium salt,5'-鸟苷酸二钠,鸟苷钠5'-单磷酸,GMP-5	Others; Endogenous Metabolite	Metabolism; Others
	5'-Guanylic acid disodium salt (GMP-5) 由鸟嘌呤，核糖和磷酸组成，是信使 RNA 中的一种核苷酸单体。鸟苷衍生物参与细胞内信号转导，并已鉴定存在于端粒，核糖体 DNA，免疫球蛋白重链转换区和原癌基因的控制区中的重复基因组序列中。
T37520	DL-Glutamic acid
	DL-Glutamic acid, the conjugate acid of Glutamic acid, serves as a crucial metabolite. In comparison to the α and β polymorphs of L-Glutamic acid's second phase, DL-Glutamic acid exhibits enhanced stability[1].

天然产物

L-Glutamic acid

Cat.No: T2A2497

Synonym: 谷氨酸,(S)-Glutamic acid,glutamic acid,(+)-L-Glutamic acid,Aciglut,L-谷氨酸,glutacid,Glutaminol

Target: Apoptosis, Ferroptosis, Endogenous Metabolite, iGluR

L-Glutamic acid monosodium salt

Cat.No: T6871

Synonym: Monosodium glutamate,谷氨酸单钠盐,Glutacyl,Glutavene,L-谷氨酸单钠盐,Ajinomoto,MSG

Target: Apoptosis, Ferroptosis, GluR, iGluR

N-Acetyl-L-glutamic acid

Cat.No: T5267

Synonym: Ac-L-Glu-OH,N-乙酰-L-谷氨酰胺,N-Acetylglutamic acid

Target: Others, Endogenous Metabolite

Cat.No: T0326L

Synonym: L-Glutamic acid 5-amide,L-谷氨酰胺

Target: Ferroptosis, Endogenous Metabolite, GluR

D-Glutamic acid

Cat.No: T10935

Synonym: (R)-Glutamic acid,D-谷氨酸

Target: Endogenous Metabolite

L-Pyroglutamic acid

Cat.No: T0507

Synonym: L-焦谷氨酸,pidolic acid,L-pyroglutamate,5-Oxoproline

Target: Others, Endogenous Metabolite

5'-Guanylic acid disodium salt

Cat.No: T4901

Synonym: Guanosine 5'-monophosphate disodium salt,5'-鸟苷酸二钠,鸟苷钠5'-单磷酸,GMP-5

Target: Others, Endogenous Metabolite

DL-Glutamic acid

Cat.No: T37520

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