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Cat. No.	Product Name	Target	Signaling Pathways
T2192	Indazole	Sodium Channel	Membrane transporter/Ion channel
	Indazole 又称benzpyrazole 或isoindazone，它的衍生物表现出广泛的生物活性，吲哚唑及其衍生物可用于癌症、神经系统疾病、心血管疾病、胃肠道疾病的研究
T25534	Indazole-Cl Indazole Cl	Estrogen/progestogen Receptor	Endocrinology/Hormones
	Indazole-Cl 是一种选择性雌激素受体激动剂和选择性雌激素受体调节剂（SERM）。
T83625	iNOS-IN-14 3-bromo-1H-indazole-7-carbonitrile	NOS	Immunology/Inflammation
	iNOS-IN-14 (3-bromo-1H-indazole-7-carbonitrile) 是一种有效的一氧化氮合酶(NOS)抑制剂，抑制nNOS的NADPH氧化酶活性。
T22988	MK-4827 Racemate Niraparib Racemate,2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	MK-4827 Racemate (Niraparib Racemate) 是一种选择性 PARP1 和 PARP2 抑制剂，IC50 分别为 3.8 nM 和 2.1 nM，对 PARP3、V-PARP 和 Tank1 的选择性超过 330 倍。
T28886	Suprafenacine N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide	Microtubule Associated	Cytoskeletal Signaling
	Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) 是一种细胞渗透性微管去稳定剂，可在 G2/M 期诱导细胞周期停滞和细胞凋亡。它与微管结合并抑制秋水仙碱连接处的聚集。它对癌细胞有选择性，包括耐药癌细胞。
Fr21265	2-Methyl-2H-indazole-3-carboxylic acid
	2-Methyl-2H-indazole-3-carboxylic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 Fr21265，CAS号为 34252-44-3。
T32417	KP1019 FFC14A,KP 1019,indazolium trans-tetrachlorobis(1H-indazole)ruthenate-(III)
	KP1019 is now discontinued.
T7474	7-Nitroindazole	NOS	Immunology/Inflammation
	7-Nitroindazole 是一种具有抗损伤及心血管作用的选择性nNOS 抑制剂，也是评价一氧化氮在中枢神经系统中生物学效应的有效工具。
T1369	1-Methylindazole-3-carboxylic acid	Others	Others
	1-Methylindazole-3-carboxylic acid 是一种具有适当沸点的优良溶剂。
T10107	3-Bromo-7-nitroindazole	NOS	Immunology/Inflammation
	3-Bromo-7-nitroindazole 是有效的、选择性的神经元型一氧化氮合酶抑制剂，对 eNOS 或诱导型一氧化氮合酶的效果相对较弱。3-Bromo-7-nitroindazole 对全身和大脑中的细胞间信使一氧化氮的合成都有影响。
T67133	6-Hydroxyindazole
	6-Hydroxyindazole 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67133，CAS号为 23244-88-4。
T0239	Lonidamine AF1890,氯尼达明,DICA,Diclondazolic Acid	Apoptosis; Hexokinase; Mitochondrial Metabolism	Apoptosis; Metabolism
	Lonidamine (Diclondazolic Acid) 是一种抗肿瘤药物，是己糖激酶、线粒体丙酮酸载体和质膜单羧酸转运蛋白抑制剂，同时也抑制线粒体复合物 II。
T8807	Benzydamine	Others	Others
	Benzydamine 是一种苄基吲唑，具有镇痛、解热和抗炎作用。 Benzydamine 用于减少手术后和创伤后的疼痛和水肿，并促进愈合。
T64396	Antiviral agent 38	Antiviral	Immunology/Inflammation
	Antiviral agent 38具有抗菌和抗病毒活性，可用来研究乙肝病毒。
T28006	MDMB-CHMINACA (S)-MDMB-CHMINACA
	MDMB-CHMINACA, an indazole-based synthetic cannabinoid, acts as a potent agonist of the CB1 receptor.
T28310	PD 114595 PD-114595,PD114595
	PD 114595 is a Benzothiopyrano-indazole cpd. PD 114595 belongs to a class of DNA complexers, PD 114595 has curative properties against murine solid tumor models.
T19322	FKK	Others	Others
	FKK is an indazole derivative and also a novel bronchodilator.
T30103	APP-CHMINACA PX-3,PX3
	APP-CHMINACA is a synthetic cannabinoid (CB) featuring a 1-(cyclohexylmethyl)-1H-indazole-3-carboxamide (CHMINACA) base. It displays a 10-fold greater affinity for the central CB1 receptor than that of JWH 018.
T11416	Glucagon receptor antagonists-5	Others	Others
	Glucagon receptor antagonists-5 is an orally bioavailable indazole-based glucagon receptor antagonist (Ki: 32 nM). It has potential for the treatment of type 2 diabetes mellitus (T2DM).
T28320	PD 121373 PD121373,PD-121373
	PD 121373 is a Benzothiopyrano-indazole cpd. The benzothiopyranoindazoles are potent inhibitors of nucleic acid synthesis, reducing both DNA and RNA synthesis to the same extent at similar concentrations.
T27013	CHS-111 CHS 111
	CHS-111 is a benzyl indazole compound. CHS-111 inhibits superoxide anion (O(2)(-)) generation. CHS-111 reduces the fMLP-stimulated PLD activity (IC(50) 3.9±1.2μM). CHS-111 inhibits the interaction of PLD1 with ADP-ribosylation factor (Arf) 6 and Ras homol
T80922	Tubulin polymerization-IN-56
	Tubulin polymerization-IN-56（compound 8l），一种吲唑衍生的微管蛋白聚合抑制剂，通过与秋水仙碱位点的相互作用，能够引发细胞周期停滞与细胞凋亡。该化合物还能降低细胞迁移并在体内更有效地抑制肿瘤生长。
T60793	Tubulin inhibitor 26
	Tubulin inhibitor 26 (compound 3c) 是一种吲唑衍生物，是微管蛋白抑制剂，对 HepG2、HCT116、SW620、HT29 和 A549 癌细胞系具有显著的低纳摩尔效力。Tubulin inhibitor 26 抑制G2/M 期肿瘤细胞，并且诱导细胞凋亡。Tubulin inhibitor 26 在体内抑制肿瘤生长，并且不影响小鼠体重。

化合物

Cat.No: T2192

Target: Sodium Channel

Cat.No: T25534

Synonym: Indazole Cl

Target: Estrogen/progestogen Receptor

Cat.No: T83625

Synonym: 3-bromo-1H-indazole-7-carbonitrile

Target: NOS

MK-4827 Racemate

Cat.No: T22988

Synonym: Niraparib Racemate,2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide

Target: PARP

Cat.No: T28886

Synonym: N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide

Target: Microtubule Associated

2-Methyl-2H-indazole-3-carboxylic acid

Cat.No: Fr21265

Cat.No: T32417

Synonym: FFC14A,KP 1019,indazolium trans-tetrachlorobis(1H-indazole)ruthenate-(III)

7-Nitroindazole

Cat.No: T7474

Target: NOS

1-Methylindazole-3-carboxylic acid

Cat.No: T1369

Target: Others

3-Bromo-7-nitroindazole

Cat.No: T10107

Target: NOS

6-Hydroxyindazole

Cat.No: T67133

Cat.No: T0239

Synonym: AF1890,氯尼达明,DICA,Diclondazolic Acid

Target: Apoptosis, Hexokinase, Mitochondrial Metabolism

Cat.No: T8807

Target: Others

Antiviral agent 38

Cat.No: T64396

Target: Antiviral

Cat.No: T28006

Synonym: (S)-MDMB-CHMINACA

Cat.No: T28310

Synonym: PD-114595,PD114595

Cat.No: T19322

Target: Others

Cat.No: T30103

Synonym: PX-3,PX3

Glucagon receptor antagonists-5

Cat.No: T11416

Target: Others

Cat.No: T28320

Synonym: PD121373,PD-121373

Cat.No: T27013

Synonym: CHS 111

Tubulin polymerization-IN-56

Cat.No: T80922

Tubulin inhibitor 26

Cat.No: T60793

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