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Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0066 |
Human CD34+ Cell Enrichment Kit (positive selection)
人 CD34+ 细胞富集试剂盒 (阴选) |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T69057 |
Elliptinium acetate
NSC 264137,Celiptium,NSC 264137 ; Celiptium |
||
Elliptinium acetate (NSC 264137)为DNA插层剂,对L1210细胞显示出明显细胞毒性,并能与其核酸进行共价结合。该化合物主要用于癌症研究,特别是转移性乳腺癌。 | |||
T13462 |
(+)-DHMEQ
(1R,2R,6R)-Dehydroxymethylepoxyquinomicin,(1R,2R,6R)-DHMEQ |
Others | Others |
(+)-DHMEQ is an antioxidant transcription factor Nrf2 activator. (+)-DHMEQ is the enantiomer of (-)-DHMEQ. | |||
T11018 |
DHMEQ racemate
rel-DHMEQ |
NF-κB | NF-κB |
DHMEQ racemate is an NF-κB inhibitor. The activity of DHMEQ racemate is lower than (-)-DHMEQ. | |||
T82222 |
H-D-MeAla-EtVaI-VaI-MeLeu-AIa-D-AIa-MeLeu-MeLeu-MeVaI-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe
|
||
H-D-MeAla-EtVal-Val-MeLeu-AIa-D-AIa-MeLeu-MeLeu-MeVal-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe 是一种非免疫抑制性的环孢菌素A衍生物,具备研究先天性肌营养不良症潜力[1]。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN3525 |
Boehmenan
|
ERK; Phosphatase; EGFR; PARP; MEK; Wnt/beta-catenin; Akt; Caspase; STAT; p53 | Angiogenesis; Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; JAK/STAT signaling; MAPK; Metabolism; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells; Tyrosine Kinase/Adaptors |
(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in a competitive manner. Boehmenan exhibits the potent cytotoxic effects against many cancer cell | |||
TN5423 | Bisdemethoxyboehmenan | ||
Bisdemethoxyboehmenan 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5423,CAS号为 146918-26-5。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02869 |
MMP-12 Protein, Human, Recombinant (catalytic domain)
HME,ME,MMP-12,MME,matrix metallopeptidase 12 |
Human | E. coli |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, ... |