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Search Results for " hip "

Targets Recommended: Hippo pathway Others

29

抑制剂 & 化合物

7

天然产物

9

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T22479	(±)-HIP-A	Others	Others
	(±)-HIP-A is an excitatory amino acid transporter blocker.
T22480	(±)-HIP-B	Others	Others
	(±)-HIP-B is an excitatory amino acid transporter blocker.
T20812	Azamethiphos 甲基吡啶磷,唑啶磷	AChE	Neuroscience
	Azamethiphos 是有机磷杀虫剂和神经毒性物质，能够抑制乙酰胆碱酯酶的活性。
T8365	Methenamine Hippurate	Antibacterial	Microbiology/Virology
	Methenamine hippurate 是一种口服活性尿液广谱抗菌剂。它对大多数常见的尿路病原体有效。
T12901	SHIP2-IN-1	Phosphatase	Metabolism
	SHIP2-IN-1 是一种 SHIP2 抑制剂，IC50=2 µM。它能够使 GSK3β 的 Ser9 位点磷酸化，抑制 GSK3β 的活化。它可用于研究阿尔滋海默症。
T5039	Aminohippurate sodium Sodium 4-aminohippurate Hydrate,Sodium p-aminohippurate,4-氨基马尿酸钠盐,p-Aminohippuric acid sodium salt	Others	Others
	Aminohippurate sodium (Sodium p-aminohippurate) 是能够利用肾血浆流量测量肾脏医学测试的诊断剂。
T50000	2-Iodohippuric Acid	Others	Others
	2-Iodohippuric Acid 可以用来测量肾脏的清除率用于肾功能研究，也用于某些疾病的诊断，如肝病和肾病。此外，它还用于某些药物的合成。
T34169	Prothipendyl
	Prothipendyl is a neuroleptic azaphenothiazine.
T76610	Hippuryl-His-Leu-OH
	Hippuryl-His-Leu-OH 是一种血管紧张素 I 转换酶的活性检测底物。Hippuryl-His-Leu-OH 释放的 His-Leu 能与邻苯二甲醛或荧光胺 (Fluorescamine) 反应，用于荧光检测。
T26711	Aza-THIP
	Aza-THIP is a GABA-C-selective antagonist.
T81368	Prothipendyl hydrochloride
	Prothipendyl hydrochloride 适用于研究老年人精神症状（例如焦虑）。
T32078	Hippuric acid, 5-amino-2-(octyloxy)-, hydrochloride
	Hippuric acid, 5-amino-2-(octyloxy)-, hydrochloride is a bioactive chemical.
T65235	Hexahydrohippuric acid
	Hexahydrohippuric acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65235，CAS号为 32377-88-1。
T28770	SHIP-2a SHIP 2a
	SHIP-2a is a cystathione γ lyase (CSE) inhibitor with IC50 value of 6.3 μM.
T33785	o-Iodohippurate sodium Hippodin,NSC-63351,Sodium iodohippurate NSC 63351,NSC63351
	o-Iodohippurate sodium is an analogue of p-aminohippuric acid used to determine effective renal plasma flow. Labelled OIH has a higher clearance than other radiopharmaceutical yet developed and is extremely suitable for renography. It is eliminated mainly
T24181	Isothipendyl hydrochloride NSC-169186,NSC 169186,NSC169186
	Isothipendyl hydrochloride is a 1st generation H1 antagonist.
T32077	Hippeastrine Hydrobromide (+)-Hippeastrine HBr,Hippeastrine HBr
	Hippeastrine hydrobromide is a natural alkaloid which demonstrates significant cytotoxicity against a panel of human and murine tumor cell lines.
T29464	5-OH-PhIP 5 OH PhIP
	5-OH-PhIP is a PhIP metabolite.
T32076	Hippadine
	Hippadine is isolated from Crinum bulbs and has reproductive effect.
T34027	PhIP-D3 PhIP D3
	PhIP-D3 is a deuterated internal standard for PhIP.
T32233	Isothipendyl Udantol,Isothipendylum,Odantol,Andanton,Nilergex
	Isothipendyl is the first generation of H1 antagonists (antihistamines) and anticholinergics and has an effect on itching.
T27544	Hippuristanol
	Hippuristanol is a potent steroid inhibitor of eukaryotic initiation factor 4A (eIF4A).
T24140	HIPP CtBP inhibitor
	HIPP is a highly selective inhibitor of antineoplastic CtBP.
T36224	N-Hippuryl-His-Leu (hydrate)
	N-Hippuryl-His-Leu (hydrate) is a synthetic substrate for angiotensin-converting enzyme (ACE) that has been used in the in vitro identification of ACE inhibitors.,
T33560	N2-OH-PhIP N-OH PhIP,N2OHPhIP,N2 OH PhIP,N-Hydroxy PhIP
	N2-OH-PhIP is a PhIP metabolite.
TF0050	Amphipol A8-35
	Amphipol A8-35 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TF0050，CAS号为 326856-53-5。
T6739	Zoledronic Acid CGP-4244,CGP42446A,唑来膦酸,Zoledronate,CGP 42446,ZOL 446,Zometa	Apoptosis; Rho; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint
	Zoledronic Acid (ZOL 446) 是一种含氮二磷酸盐，能抑制破骨细胞的分化和凋亡，具有高效的抗骨质再吸收活性，也有抗癌作用。
T71551	KAI-1678
	KAI-1678 is an inhibitor of epsilon protein kinase C (εPKC). KAI-1678 is effective in the treatment of postoperative pain following total hip or total knee replacement.
T68435	Cilazapril HCl
	Cilazapril, also known as Ro 31 2848, is a potent ACE inhibitor used for hypertension. Cilazapril is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. Cilazapril is a monoethyl ester, which acts as an angiotensin-converting enzyme (ACE) inhibitor. The inhibitor functions by inhibiting the ability of ACE to cleave bonds of angiotensin I and Hip-His-Leu. It is known that the diacid form of Cilazapril is more potent that enalapril at inhibiting ACE.

化合物

Cat.No: T22479

Target: Others

Cat.No: T22480

Target: Others

Cat.No: T20812

Synonym: 甲基吡啶磷,唑啶磷

Target: AChE

Methenamine Hippurate

Cat.No: T8365

Target: Antibacterial

Cat.No: T12901

Target: Phosphatase

Aminohippurate sodium

Cat.No: T5039

Synonym: Sodium 4-aminohippurate Hydrate,Sodium p-aminohippurate,4-氨基马尿酸钠盐,p-Aminohippuric acid sodium salt

Target: Others

2-Iodohippuric Acid

Cat.No: T50000

Target: Others

Cat.No: T34169

Hippuryl-His-Leu-OH

Cat.No: T76610

Cat.No: T26711

Prothipendyl hydrochloride

Cat.No: T81368

Hippuric acid, 5-amino-2-(octyloxy)-, hydrochloride

Cat.No: T32078

Hexahydrohippuric acid

Cat.No: T65235

Cat.No: T28770

Synonym: SHIP 2a

o-Iodohippurate sodium

Cat.No: T33785

Synonym: Hippodin,NSC-63351,Sodium iodohippurate NSC 63351,NSC63351

Isothipendyl hydrochloride

Cat.No: T24181

Synonym: NSC-169186,NSC 169186,NSC169186

Hippeastrine Hydrobromide

Cat.No: T32077

Synonym: (+)-Hippeastrine HBr,Hippeastrine HBr

Cat.No: T29464

Synonym: 5 OH PhIP

Cat.No: T32076

Cat.No: T34027

Synonym: PhIP D3

Cat.No: T32233

Synonym: Udantol,Isothipendylum,Odantol,Andanton,Nilergex

Hippuristanol

Cat.No: T27544

Cat.No: T24140

Synonym: CtBP inhibitor

N-Hippuryl-His-Leu (hydrate)

Cat.No: T36224

Cat.No: T33560

Synonym: N-OH PhIP,N2OHPhIP,N2 OH PhIP,N-Hydroxy PhIP

Cat.No: TF0050

Zoledronic Acid

Cat.No: T6739

Synonym: CGP-4244,CGP42446A,唑来膦酸,Zoledronate,CGP 42446,ZOL 446,Zometa

Target: Apoptosis, Rho, Autophagy

Cat.No: T71551

Cat.No: T68435

Cat. No.	Product Name	Target	Signaling Pathways
T1436	4-Aminohippuric Acid p-Aminohippuric acid,对氨基马尿酸	Amino Acids and Derivatives; Endogenous Metabolite	Metabolism
	4-Aminohippuric Acid 是诊断剂，能够用于肾脏检测，在肾血浆流量的测定中使用。
T16525	PhIP	Others	Others
	PhIP 是来源于熟肉的一种杂环芳香胺(HAA)，属于吡啶类杂环胺，是2B 类致癌物，具有雌激素活性。PhIP 可与 DNA 形成加合物，从而促进癌症发生。
TN7118	Methylhippuric acid Methyl hippurate,N-苯甲酰基甘氨酸甲酯
	Methylhippuric acid (Methyl hippurate) 是人体尿液中二甲苯暴露的生物标志物。
T4815	Hippuric acid 马尿酸,2-Benzamidoacetic acid,Benzoylglycine	Others; Endogenous Metabolite	Metabolism; Others
	Hippuric acid (2-Benzamidoacetic acid) 是一种正常的尿液成分，是苯酸和甘氨酸结合作用下产生的一种酰基甘氨酸，来自食物的芳香化合物的代谢。
T14031	3-Hydroxyhippuric acid	Others	Others
	3-Hydroxyhippuric acid is an acyl glycine, which are normally minor metabolites of fatty acids.
T75655	Hippeastrine
	Hippeastrine 是一种活性生物碱，对拓扑异构酶 ITop I 具有良好的剂量依赖性抑制作用，IC50为7.25 μg/mL。具有抗增殖和抗癌活性。
T35972	4-Hydroxy-hippuric acid 4-Hydroxy-hippuric acid,p-Hydroxyhippuric Acid,para-Hydroxyhippuric Acid
	Polyphenol metabolite.

天然产物

4-Aminohippuric Acid

Cat.No: T1436

Synonym: p-Aminohippuric acid,对氨基马尿酸

Target: Amino Acids and Derivatives, Endogenous Metabolite

Cat.No: T16525

Target: Others

Methylhippuric acid

Cat.No: TN7118

Synonym: Methyl hippurate,N-苯甲酰基甘氨酸甲酯

Hippuric acid

Cat.No: T4815

Synonym: 马尿酸,2-Benzamidoacetic acid,Benzoylglycine

Target: Others, Endogenous Metabolite

3-Hydroxyhippuric acid

Cat.No: T14031

Target: Others

Cat.No: T75655

4-Hydroxy-hippuric acid

Cat.No: T35972

Synonym: 4-Hydroxy-hippuric acid,p-Hydroxyhippuric Acid,para-Hydroxyhippuric Acid

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03673	REG3B Protein, Mouse, Recombinant (His) Pap,HIP,REG-III,PAP1	Mouse	HEK293 Cells
	Expression of REG3B was sufficient to inhibit cytokine-induced activation of STAT3 in IECs. The human REG3beta protein, the functional counterpart of mouse REG3B, inhibited STAT3 activity in human 293T cells, and its expression level in colorectal tumors correlated inversely with pSTAT3 level and survival times of patients. REG3B negatively regulates cytokine-induced activation of STAT3 in colon epithelial cells. This pathway might be targeted in patients with colitis to reduce carcinogenesis.
TMPY-01336	REG3A Protein, Human, Recombinant (His) HIP/PAP,INGAP,REG3,PAP1,PAP-H,regenerating family m...	Human	HEK293 Cells
	REG3A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18 kDa and the accession number is Q06141-1.
TMPJ-01038	UBE2K Protein, Human, Recombinant (GST) Ubiquitin-Conjugating Enzyme E2(25K),Ubiquitin Carrier Prote...	Human	E. coli
	UBE2K Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 45 KDa and the accession number is P61086.
TMPJ-01039	UBE2K Protein, Human, Recombinant (His & SUMO) Ubiquitin-Conjugating Enzyme E2-25 kDa,Huntingtin-Interactin...	Human	E. coli
	UBE2K Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis and SUMO tag. The predicted molecular weight is 38 KDa and the accession number is P61086.
TMPY-03501	Optineurin Protein, Human, Recombinant (His & GST) optineurin,HIP7,ALS12,HYPL,TFIIIA-INTP,FIP2,NRP,GLC...	Human	Baculovirus Insect Cells
	OPTN (Optineurin) is a Protein Coding gene. The Optineurin gene encodes the coiled-coil containing protein optineurin. Optineurin is a multifunctional adaptor protein intimately involved in various vesicular trafficking pathways. Through interactions with an array of proteins, such as myosin VI, huntingtin, Rab8, and Tank-binding kinase 1, as well as via its oligomerization, optineurin can act as an adaptor, scaffold, or signal regulator to coordinate many cellular processes associated with the ...
TMPY-03847	FRZB Protein, Human, Recombinant (His) frizzled-related protein,FRITZ,OS1,SFRP3,FRZB-PEN,FRP-3,FRE,...	Human	HEK293 Cells
	FRZB also known as sFRP-3, is a secreted protein containing a domain similar to the putative Wnt-binding region of the frizzled family of transmembrane receptors. FRZB is widely expressed in adult mammalian tissues. In the Xenopus gastrula, FRZB is regulated as a typical Spemann organizer component. FRZB also functions as a competitor for the cell-surface G-protein receptor Frizzled. It is espically important in embryonic development. Defects in FRZB gene can cause female-specific osteoarthritis...
TMPJ-00717	BAG2 Protein, Human, Recombinant (His) BAG-2,BAG Family Molecular Chaperone Regulator 2,BAG2,Bcl-2-...	Human	E. coli
	BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
TMPJ-00915	HSP40 Protein, Human, Recombinant (His) HDJ1,HSPF1,DNAJ1,Heat Shock 40 kDa Protein 1,HSP40,hDj-1,DNA...	Human	E. coli
	DnaJ Homolog Subfamily B Member 1 (DNAJB1) is a member of the heat shock protein family. Heat shock proteins (HSPs) are a highly conserved family of stress response proteins. HSPs function primarily as molecular chaperones, facilitating the folding of other cellular proteins, preventing protein aggregation, or targeting improperly folded proteins to specific degradative pathways. DNAJB1 regulates cellular processes by aiding in the folding, transport and assembly. DNAJB1 contains a J-domain whic...
TMPY-03384	CALM2 Protein, Human, Recombinant (His) caM,calmodulin 2 (phosphorylase kinase, delta),PHKD,calmodul...	Human	E. coli
	Calmodulin 2, also known as CALM2, is a calmodulin. Calmodulin 2 mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). It is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Calmodulin 2 gene may be a genetic determinant of hip osteoarthritis (OA). OA is a degenerative disease characterized by gradual loss of articular cartilage and is a leading cause of disability in elderly populations. CALM2 was most...

重组蛋白

REG3B Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03673

Species: Mouse

Expression System: HEK293 Cells

REG3A Protein, Human, Recombinant (His)

Cat.No: TMPY-01336

Species: Human

Expression System: HEK293 Cells

UBE2K Protein, Human, Recombinant (GST)

Cat.No: TMPJ-01038

Species: Human

Expression System: E. coli

UBE2K Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPJ-01039

Species: Human

Expression System: E. coli

Optineurin Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-03501

Species: Human

Expression System: Baculovirus Insect Cells

FRZB Protein, Human, Recombinant (His)

Cat.No: TMPY-03847

Species: Human

Expression System: HEK293 Cells

BAG2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00717

Species: Human

Expression System: E. coli

HSP40 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00915

Species: Human

Expression System: E. coli

CALM2 Protein, Human, Recombinant (His)

Cat.No: TMPY-03384

Species: Human

Expression System: E. coli

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