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Cat. No.	Product Name	Target	Signaling Pathways
T73331	GSK3-IN-3	Mitophagy; GSK-3	Autophagy; PI3K/Akt/mTOR signaling; Stem Cells
	GSK3-IN-3 是一种线粒体自噬 (mitophagy) 诱导剂和GSK-3 抑制剂（IC50 ： 3.01 μM），可诱导帕金依赖性线粒体自噬。 GSK3-IN-3 具有非 ATP 和非底物竞争性，对 6-OHDA 有神经保护作用。
T9987	GSK3-IN-1	GSK-3	PI3K/Akt/mTOR signaling; Stem Cells
	GSK3-IN-1是一种 GSK3B-糖原合酶激酶3β抑制剂。
T35555	GSK-3/CDK5/CDK2-IN-1 GSK-3/CDK5/CDK2-IN-1
	GSK-3/CDK5/CDK2-IN-1 is an imidazole derivative compound that inhibits cdk5, cdk2, and GSK-3.it has demonstrated applications in cancer research and the study of neurodegenerative diseases [1].
T64366	GSK3-IN-4	GSK-3	PI3K/Akt/mTOR signaling; Stem Cells
	GSK3-IN-4是一种 GSK-3抑制剂，对 GSK-3α和 GSK-3β的IC50值为 0.101-1 μM。
T2608	CHIR-98014 CHIR 98014,CT98014,CHIR98014	FGFR; GSK-3; Src; S6 Kinase	Angiogenesis; MAPK; PI3K/Akt/mTOR signaling; Stem Cells; Tyrosine Kinase/Adaptors
	CHIR-98014 (CT98014) 是有效的，细胞通透的GSK-3抑制剂，可抑制 GSK-3α (IC50:0.65 nM) 和 GSK-3β (IC50:0.58 nM) 的活性，对 cdc2 和 erk2 的作用较弱。
T16670	PS210	PDK	PI3K/Akt/mTOR signaling
	PS210 是针对 PDK1的 PIF 结合口袋的、选择性的、有效的 PDK1激活剂，对其他蛋白激酶无活性。在细胞中，它的前药 PS423 可作为 PDK1的底物选择性抑制剂，抑制 S6K 的磷酸化和活化。
T30807	CG0009 CG-0009,CG 0009
	CG0009 is a potent and highly selective glycogen synthase kinase 3 (GSK3) inhibitor that inhibitions proliferation, induces apoptosis, and activates the p53-Bax pathway in breast cancer cells through cyclin D1 depletion. CG0009 inhibit breast cancer cell
T74033	6-Me-ATP
	6-Me-ATP（N6-Methyl-ATP）为ATP的N6修饰衍生物。该化合物与GSK3β结合亲和力显著，能有效作为GSK3β催化底物肽磷酸化的磷酸基团供体。
T35541	Lipoxygenin
	Lipoxygenin is an inhibitor of 5-lipoxygenase (5-LO) with an IC50value of 5 μM for inhibition of 5-LO product synthesis in isolated human granulocytes stimulated with the cation ionophore A23187 .1It inhibits hedgehog-dependent signaling in Shh-LIGHT2 cells and TGF-β-, activin A-, bone morphogenic protein (BMP)-, or Wnt-dependent signaling in HEK293T cells (IC50s = 9.3, 3.2, 8.2, 9.6, and 3.7 μM, respectively, in luciferase reporter assays). Lipoxygenin (5 and 10 μM) increases levels of troponin...