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Search Results for " erbb1 "

Targets Recommended: EGFR

3

抑制剂 & 化合物

20

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T8758	Poziotinib hydrochloride HM 781-36B hydrochloride,NOV120101 hydrochloride,波齐替尼盐酸盐	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Poziotinib hydrochloride 不可逆地抑制 EGFR（HER1 或 ErbB1），包括 EGFR 突变体、HER2 和 HER4，从而抑制过度表达这些受体的肿瘤细胞的增殖。它是一种口服生物可利用的、基于喹唑啉的泛表皮生长因子受体（EGFR 或 HER）抑制剂，具有潜在的抗肿瘤活性。
T2518	ARRY-380 (analog ) HER2-Inhibitor-1,ARRY380,ARRY-380 analog	EGFR; HER	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	ARRY-380 analog (HER2-Inhibitor-1) 是EGFR (ErbB1)的抑制剂。
T20954	Varlitinib Tosylate Varlitinib-Tosylate,ARRY-334543 Tosylate,ARRY-543 Tosylate
	Varlitinib Tosylate is a selective and potent inhibitor of ErbB1(EGFR) and ErbB2(HER2).

化合物

Poziotinib hydrochloride

Cat.No: T8758

Synonym: HM 781-36B hydrochloride,NOV120101 hydrochloride,波齐替尼盐酸盐

Target: EGFR

ARRY-380 (analog )

Cat.No: T2518

Synonym: HER2-Inhibitor-1,ARRY380,ARRY-380 analog

Target: EGFR, HER

Varlitinib Tosylate

Cat.No: T20954

Synonym: Varlitinib-Tosylate,ARRY-334543 Tosylate,ARRY-543 Tosylate

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00742	EGFR Protein, Human, Recombinant (His) mENA,NISBD2,ERBB1,HER1,PIG61<...	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.8 kDa and the accession number is P00533-1.
TMPY-04529	EGFR Protein, Human, Recombinant (aa 668-1210, His & GST) epidermal growth factor receptor,PIG61,ERBB	Human	Baculovirus Insect Cells
	EGFR Protein, Human, Recombinant (aa 668-1210, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 89.1 kDa and the accession number is P00533-1.
TMPY-06549	EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His) ERBB,epidermal growth factor receptor,HER1...	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.09 kDa and the accession number is NP_001333870.1.
TMPK-00689	EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled EC 2.7.10.1,EC 2.7.10,ERBB	Human	HEK293 Cells
	The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled is expre...
TMPY-05612	EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated mENA,PIG61,HER1,ERBB1,	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 71.9 kDa and the accession number is P00533-1.
TMPY-05258	EGFR Protein, Human, Recombinant (Isoform Viii, hFc) NISBD2,epidermal growth factor receptor,ERBB,PIG6	Human	Baculovirus Insect Cells
	EGFR Protein, Human, Recombinant (Isoform Viii, hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 65.1 kDa and the accession number is NP_001333870.1.
TMPK-00692	EGFRVIII Protein, Human, Recombinant (His & Avi), Biotinylated EC 2.7.10.1,PIG61,NISBD2,HER1...	Human	HEK293 Cells
	The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRVIII Protein, Human, Recombinant (His & Avi), Biotinylated is exp...
TMPK-00691	EGFRVIII Protein, Human, Recombinant (His & Avi) EGFR,ErbB,mENA,HER1,LEGFR,EC 2.7.1	Human	HEK293 Cells
	The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRVIII Protein, Human, Recombinant (His & Avi) is expressed in HEK2...
TMPY-05211	EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His) NISBD2,PIG61,ERBB,mENA,epidermal growth fa...	Human	Baculovirus Insect Cells
	EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 39.3 kDa and the accession number is NP_001333870.1.
TMPY-01043	EGFR Protein, Human, Recombinant (hFc) ERBB,mENA,HER1,ERBB1,PIG...	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95 kDa and the accession number is P00533-1.
TMPY-05637	EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated epidermal growth factor receptor,HER1,mENA,ERBB...	Human	Baculovirus Insect Cells
	EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 41.8 kDa and the accession number is NP_001333870.1.
TMPY-06593	EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated PIG61,ERBB1,ERBB,NISBD2,...	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 41.90 kDa and the accession number is NP_001333870.1.
TMPK-00425	EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled EC 2.7.10.1,HER1,EGFR,PIG61	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.5 kDa and the accession number is P00533-1.
TMPK-00426	EGFR Protein, Human, Recombinant (His & Avi) PIG61,mENA,NISBD2,EC 2.7.10.1,HER...	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.5 kDa and the accession number is P00533-1.
TMPK-00427	EGFR Protein, Human, Recombinant (His & Avi), Biotinylated PIG61,ERBB,LEGFR,mENA,EC 2.7.10.<...	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.5 kDa and the accession number is P00533-1.
TMPK-00902	EGFR Protein, Rhesus macaque, Recombinant (His) HER1,EC 2.7.10,EGFR,NISBD2,ErbB,P...	Rhesus	HEK293 Cells
	EGFR Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.8 kDa and the accession number is P55245.
TMPK-00690	EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled LEGFR,ERBB1,EGFR,HER1,PIG61	Human	HEK293 Cells
	The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled is exp...
TMPY-02708	NRG4 Protein, Human, Recombinant HRG4,neuregulin 4	Human	E. coli
	NRG4 (neuregulin 4) is a member of the neuregulin protein family. The neuregulins consist of four structurally-related proteins that are part of the EGF family of proteins. It has been shown that these proteins have diverse functions in the development of the nervous system and play multiple essential roles in vertebrate embryogenesis including cardiac development, Schwann cell, and oligodendrocyte differentiation, some aspects of neuronal development, as well as the formation of neuromuscular s...
TMPJ-01286	proHB-EGF Protein, Human, Recombinant (His) heparin-binding EGF-like growth factor,HB-EGF,HEGFL,DTS,Diph...	Human	HEK293 Cells
	Heparin-binding EGF-like growth factor (HB-EGF) is a 1216 kDa member of the epidermal growth factor (EGF) family. It possesses an EGFlike domain, and a heparin-binding motif. Mature HBEGF is a soluble peptide that arises from proteolytic processing of the transmembrane form. Human HBEGF shows 76% and 73% aa sequence identity with rat and mouse HBEGF, respectively. It is required for normal cardiac valve formation and normal heart function, promotes smooth muscle cell proliferation. It may b...
TMPJ-00448	NRG1 beta 1 Protein, Human, Recombinant (aa 2-246) NRG1β,HGL,NDF,NRG1,HRGA,HRG1-beta...	Human	E. coli
	Pro-neuregulin-1,Neuregulin-1 beta 1（NRG1） is a single-pass type I membrane protein and belongs to the neuregulin family .It contains 1 EGF-like domain and 1 Ig-like C2-type (immunoglobulin-like) domain. Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. The protein concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and ...

重组蛋白

EGFR Protein, Human, Recombinant (His)

Cat.No: TMPY-00742

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)

Cat.No: TMPY-04529

Species: Human

Expression System: Baculovirus Insect Cells

EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His)

Cat.No: TMPY-06549

Species: Human

Expression System: HEK293 Cells

EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled

Cat.No: TMPK-00689

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated

Cat.No: TMPY-05612

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (Isoform Viii, hFc)

Cat.No: TMPY-05258

Species: Human

Expression System: Baculovirus Insect Cells

EGFRVIII Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00692

Species: Human

Expression System: HEK293 Cells

EGFRVIII Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00691

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His)

Cat.No: TMPY-05211

Species: Human

Expression System: Baculovirus Insect Cells

EGFR Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01043

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated

Cat.No: TMPY-05637

Species: Human

Expression System: Baculovirus Insect Cells

EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated

Cat.No: TMPY-06593

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled

Cat.No: TMPK-00425

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00426

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00427

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPK-00902

Species: Rhesus

Expression System: HEK293 Cells

EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled

Cat.No: TMPK-00690

Species: Human

Expression System: HEK293 Cells

NRG4 Protein, Human, Recombinant

Cat.No: TMPY-02708

Species: Human

Expression System: E. coli

proHB-EGF Protein, Human, Recombinant (His)

Cat.No: TMPJ-01286

Species: Human

Expression System: HEK293 Cells

NRG1 beta 1 Protein, Human, Recombinant (aa 2-246)

Cat.No: TMPJ-00448

Species: Human

Expression System: E. coli

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