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Cat. No.	Product Name	Target	Signaling Pathways
T1076	Dexamethasone MK 125,Prednisolone F,NSC 34521,Hexadecadrol,地塞米松	Glucocorticoid Receptor; Mitophagy; IL Receptor; SARS-CoV; Antibacterial; Antibiotic; Autophagy; Complement System	Autophagy; Endocrinology/Hormones; Immunology/Inflammation; Microbiology/Virology
	Dexamethasone (Hexadecadrol) 是一种糖皮质激素受体激动剂和一种 IL 受体调节剂。Dexamethasone 具有抗炎和免疫抑制活性，可诱导自噬。Dexamethasone 抑制 LPS 诱导的巨噬细胞炎症反应。
T0947	Dexamethasone acetate Dexamethasone 21-acetate,醋酸地塞米松,Dexamethason acetate,NSC 39471	Glucocorticoid Receptor; Mitophagy; IL Receptor; Annexin A; NOS; Antibacterial; Autophagy	Autophagy; Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology
	Dexamethasone acetate (NSC 39471) 是一种糖皮质素类甾体，有抗炎和免疫抑制活性。它可研究眼部感染。
T19277	Dexamethasone 9,11-epoxide	Others	Others
	Dexamethasone 9,11-epoxide 是一种萃取得到的化合物，是制备地塞米松的中间体。
T15102	Dexamethasone palmitate 地塞米松棕榈酸酯,DXP	Glucocorticoid Receptor	Endocrinology/Hormones
	Dexamethasone palmitate (DXP) (DXP) 是 Dexamethasone 的前药。Dexamethasone 是糖皮质激素受体激动剂。与Dexamethasone 相比， DXP 对糖皮质激素受体的亲和力低 47 倍。DXP 显示出抗炎活性。
T6465	Dexamethasone Sodium Phosphate Dexadreson,地塞米松磷酸钠,Dexagro,Dalalone	IL Receptor; COX	Immunology/Inflammation; Neuroscience
	Dexamethasone Sodium Phosphate (Dexadreson) 是一种白细胞介素受体调节剂，具有抗炎和免疫抑制作用。它属于类固醇合成药物的强效糖皮质激素类。
T0947L	Dexamethasone Phosphate disodium 地塞米松磷酸二钠,EGP-437,EGP437. Dex-Phos,EGP 437	Glucocorticoid Receptor	Endocrinology/Hormones
	Dexamethasone Phosphate disodium (EGP437. Dex-Phos) 是糖皮质激素受体激动剂。
T21074	Dexamethasone acetate Dexamethasone 21-acetate monohydrate,Decadron-LA,Decadron
	Dexamethasone acetate is an adrenocortical steroid. It is used in the treatment of many conditions, including rheumatic problems, a number of skin diseases, asthma, severe allergies, chronic obstructive lung disease, brain swelling, croup, and antibiotics
T39088	Mc-Dexamethasone
	Mc-Dexamethasone is a drug-linker conjugate for ADC . Mc-Dexamethasone is made toxin Dexamethasone conjugated to the non-cleavable MC linker. Dexamethasone is a glucocorticoid receptor agonist.
T37361	6β-hydroxy Dexamethasone
	6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound. Dexamethasone is metabolized by CYP3A4; therefore, quantification of the dexamethasone metabolites, 6α- and 6β-hydroxy dexamethasone, can be used to determine CYP3A4 enzyme activity in humans., The formation of 6-hydroxy dexamethasone metabolites is species-specific, with hamsters producing the highest amount. In rats, dexamethasone hydroxylation is sex-specific, with male rats producing ...
T27152	Dexamethasone Beloxil
	Dexamethasone Beloxil is a glucocorticoid, Anti-inflammatory Agent.
T69323	Dexamethasone sodium succinate
	Dexamethasone sodium succinate is the acetate salt form of dexamethasone, which is a synthetic glucocorticoid; it combines high anti-inflammatory effects with low mineralocorticoid activity. At high doses (e.g. 40 mg), it reduces the immune response. Dexamethasone acetate (NEOFORDEX®) is indicated in adults for the treatment of symptomatic multiple myeloma in combination with other medicinal products. Dexamethasone has been shown to induce multiple myeloma cell death (apoptosis) via a down-regul...
T27153	Dexamethasone cipecilate NS126,NS-126,NS 126
	Dexamethasone cipecilate is a long-acting intranasal corticosteroid and a highly lipophilic anti-inflammatory corticosteroid.
T23984	Dexamethasone phosphate Neodecadron,EGP437,Hexadrol phosphate,EGP 437,EGP-437
	Dexamethasone phosphate is a synthetic adrenal corticosteroid. It also has potent anti-inflammatory properties.
T61525	Dexamethasone oxetanone
	Dexamethasone oxetanone (Dex-Ox) is a glucocorticoid-selective derivative of Dexamethasone (Dex) compound. It acts as an antiglucocorticoid and an antiprogestin, demonstrating notable agonist activity with both PR A and B isoforms [1] [2].
T31395	Dexamethason 21-tert-butylacetate Decadron TBA,Dexamethasone tert-butylacetate
	Dexamethason 21-tert-butylacetate is a biochemical.
T2334	Avanafil 阿伐那非,TA1790	PDE	Metabolism
	Avanafil (TA1790) 是一种高活性PDE-5抑制剂，IC50=5.2 nM，对PDE1，PDE6和PDE11活性较低。
T22818	GSK9027 GR agonist 23a,GSK 9027,GSK-9027	Glucocorticoid Receptor	Endocrinology/Hormones
	GSK9027 (GR agonist 23a) 是一种非甾体糖皮质激素受体 (GR) 激动剂。GSK9027 (GR agonist 23a) 在2×GRE报告基因上对比地塞米松的活性属于部分激动剂，活性较地塞米松活性较弱。
T35386	Elotuzumab Elotuzumab (anti-SLAMF7),BMS 901608,PDL 063,HuLuc 63	Others	Others
	Elotuzumab(HuLuc 63) (anti-SLAMF7) 是一种靶向 SLAMF7 受体的单克隆抗体。Elotuzumab (anti-SLAMF7) 是一种直接激活NK细胞并诱导抗体依赖性细胞毒性的化合物，可联合来那度胺和地塞米松（Ld）用于治疗多发性骨髓瘤。
T38034	MAO-IN-M30 dihydrochloride M 30 dihydrochloride	Monoamine Oxidase	Neuroscience
	MAO-IN-M30 dihydrochloride (M 30 dihydrochloride) 是一种口服活性，可通过血脑屏障的，脑选择性不可逆 MAO-A (IC50=37 nM) 和 MAO-B (IC50=57 nM) 抑制剂。MAO-IN-M30 dihydrochloride 是有效的铁螯合剂、自由基清除剂。MAO-IN-M30 dihydrochloride 对 Dexamethasone 诱导的脑细胞凋亡具有神经保护作用。MAO-IN-M30 dihydrochloride 在 MPTP 和 lactacystin 帕金森病模型中也显示出神经恢复活性。
T24189	J9 J-9,J 9
	J9 is an inhibitor of Glucocorticoid resistance. J9 reverses Dexamethasone Resistance in T-cell Acute Lymphoblastic Leukemia.
T27999	MDK-4624 AMPKα1 activator C13,C13, Compound 13
	MDK-4624 is a AMPKα1 activator. MDK-4624 inhibits Helicobacter pylori-induced oxidative stresses and gastric epithelial cell apoptosis. MDK-4624 attenuates dexamethasone-induced osteoblast cell death. MDK-4624 potently inhibits melanoma cell proliferation
T70904	Tylogenin
	Tylogenin, a steroidal aglycone generated by acid hydrolysis from two seasonal glycosides occurring in Tylophora sylvatica, inhibits IgE-induced basophil mediator release for allergic reactions. In the rabbit basophil-dependent serotonin release (BDSR) assay system, the inhibitory activity of tylogenin was significantly greater than that of its parent glycosides, tylophoroside and acetyltylophoroside, and that of dexamethasone. The activity of tylogenin was found to increase with the incubation ...
T27790	Labradimil RMP-7,ALK-01-040,Receptor-mediated permeabiliser-7,DRG0182,DRG 0182,DRG-0182
	Labradimil is a bradykinin B2 receptor agonist. Labradimil increases the permeability of human brain microvascular endothelial cell monolayers. Labradimil enhances delivery of hydrophilic chemotherapeutics and increases survival in rats with metastatic tu
T70346	TOP1362
	TOP1362 is a Narrow Spectrum Kinase Inhibitors Demonstrate Promise for the Treatment of Dry Eye Disease and Other Ocular Inflammatory Disorders. TOP1362 strongly inhibited the kinase targets p38α, Syk, Src, and Lck, blocked the rise in p38α expression in hyperosmolar Chang cells, and potently reduced inflammatory cytokine release in cellular models of innate and adaptive immunities. In the EIU model, TOP1362 dose-dependently attenuated the LPS-induced rise in inflammatory cell infiltration and o...
T68306	INCB16562
	INCB16562 is a novel, selective, and orally bioavailable small-molecule inhibitor of JAK1 and JAK2 markedly selective over JAK3. Treatment of myeloma cells with INCB16562 potently inhibited interleukin-6 (IL-6)-induced phosphorylation of STAT3. INCB16562 abrogated the protective effects of recombinant cytokines or bone marrow stromal cells and sensitized myeloma cells to cell death by exposure to dexamethasone, melphalan, or bortezomib. Oral administration of INCB16562 antagonized the growth of ...

化合物

Dexamethasone

Cat.No: T1076

Synonym: MK 125,Prednisolone F,NSC 34521,Hexadecadrol,地塞米松

Target: Glucocorticoid Receptor, Mitophagy, IL Receptor, SARS-CoV, Antibacterial, Antibiotic, Autophagy, Complement System

Dexamethasone acetate

Cat.No: T0947

Synonym: Dexamethasone 21-acetate,醋酸地塞米松,Dexamethason acetate,NSC 39471

Target: Glucocorticoid Receptor, Mitophagy, IL Receptor, Annexin A, NOS, Antibacterial, Autophagy

Dexamethasone 9,11-epoxide

Cat.No: T19277

Target: Others

Dexamethasone palmitate

Cat.No: T15102

Synonym: 地塞米松棕榈酸酯,DXP

Target: Glucocorticoid Receptor

Dexamethasone Sodium Phosphate

Cat.No: T6465

Synonym: Dexadreson,地塞米松磷酸钠,Dexagro,Dalalone

Target: IL Receptor, COX

Dexamethasone Phosphate disodium

Cat.No: T0947L

Synonym: 地塞米松磷酸二钠,EGP-437,EGP437. Dex-Phos,EGP 437

Target: Glucocorticoid Receptor

Dexamethasone acetate

Cat.No: T21074

Synonym: Dexamethasone 21-acetate monohydrate,Decadron-LA,Decadron

Mc-Dexamethasone

Cat.No: T39088

6β-hydroxy Dexamethasone

Cat.No: T37361

Dexamethasone Beloxil

Cat.No: T27152

Dexamethasone sodium succinate

Cat.No: T69323

Dexamethasone cipecilate

Cat.No: T27153

Synonym: NS126,NS-126,NS 126

Dexamethasone phosphate

Cat.No: T23984

Synonym: Neodecadron,EGP437,Hexadrol phosphate,EGP 437,EGP-437

Dexamethasone oxetanone

Cat.No: T61525

Dexamethason 21-tert-butylacetate

Cat.No: T31395

Synonym: Decadron TBA,Dexamethasone tert-butylacetate

Cat.No: T2334

Synonym: 阿伐那非,TA1790

Target: PDE

Cat.No: T22818

Synonym: GR agonist 23a,GSK 9027,GSK-9027

Target: Glucocorticoid Receptor

Cat.No: T35386

Synonym: Elotuzumab (anti-SLAMF7),BMS 901608,PDL 063,HuLuc 63

Target: Others

MAO-IN-M30 dihydrochloride

Cat.No: T38034

Synonym: M 30 dihydrochloride

Target: Monoamine Oxidase

Cat.No: T24189

Synonym: J-9,J 9

Cat.No: T27999

Synonym: AMPKα1 activator C13,C13, Compound 13

Cat.No: T70904

Cat.No: T27790

Synonym: RMP-7,ALK-01-040,Receptor-mediated permeabiliser-7,DRG0182,DRG 0182,DRG-0182

Cat.No: T70346

Cat.No: T68306

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